ZA793293B - (di)-16-phenoxy and 16-substituted phenoxy-9-keto prostatrienoic acid derivatives and processes for the production thereof - Google Patents

(di)-16-phenoxy and 16-substituted phenoxy-9-keto prostatrienoic acid derivatives and processes for the production thereof

Info

Publication number
ZA793293B
ZA793293B ZA793293A ZA793293A ZA793293B ZA 793293 B ZA793293 B ZA 793293B ZA 793293 A ZA793293 A ZA 793293A ZA 793293 A ZA793293 A ZA 793293A ZA 793293 B ZA793293 B ZA 793293B
Authority
ZA
South Africa
Prior art keywords
phenoxy
keto
processes
production
acid derivatives
Prior art date
Application number
ZA793293A
Other languages
English (en)
Inventor
G Garay
A Van Horn
J Edwards
Original Assignee
Syntex Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Syntex Inc filed Critical Syntex Inc
Priority to IE1294/79A priority Critical patent/IE48656B1/en
Publication of ZA793293B publication Critical patent/ZA793293B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
    • C07C2601/06Systems containing only non-condensed rings with a five-membered ring
    • C07C2601/08Systems containing only non-condensed rings with a five-membered ring the ring being saturated
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/582Recycling of unreacted starting or intermediate materials

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
ZA793293A 1978-07-10 1979-07-03 (di)-16-phenoxy and 16-substituted phenoxy-9-keto prostatrienoic acid derivatives and processes for the production thereof ZA793293B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
IE1294/79A IE48656B1 (en) 1978-07-10 1979-08-08 (di)-16-phenoxy-and 16-substituted phenoxy-9-keto prostatrienoic acid derivatives and processes for the production thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/922,957 US4178457A (en) 1978-07-10 1978-07-10 (dl)-16-Phenoxy- and 16-substituted phenoxy-9-keto prostatrienoic acid derivatives and processes for the production thereof

Publications (1)

Publication Number Publication Date
ZA793293B true ZA793293B (en) 1981-02-25

Family

ID=25447871

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA793293A ZA793293B (en) 1978-07-10 1979-07-03 (di)-16-phenoxy and 16-substituted phenoxy-9-keto prostatrienoic acid derivatives and processes for the production thereof

Country Status (26)

Country Link
US (1) US4178457A (no)
EP (1) EP0008003B1 (no)
JP (1) JPS5513282A (no)
KR (1) KR890002773B1 (no)
AT (1) ATE2427T1 (no)
AU (1) AU527516B2 (no)
CA (1) CA1149802A (no)
CS (1) CS209927B2 (no)
DD (1) DD146179A5 (no)
DE (2) DE2964709D1 (no)
DK (1) DK157753C (no)
ES (1) ES482330A1 (no)
FI (1) FI69061C (no)
FR (1) FR2430939A1 (no)
GB (1) GB2025413B (no)
HK (1) HK41384A (no)
HU (1) HU184185B (no)
IT (1) IT1121462B (no)
MY (1) MY8500576A (no)
NO (4) NO150836C (no)
NZ (1) NZ190924A (no)
PL (4) PL120633B1 (no)
SG (1) SG82483G (no)
SU (1) SU1031407A3 (no)
YU (3) YU41870B (no)
ZA (1) ZA793293B (no)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4328245A (en) * 1981-02-13 1982-05-04 Syntex (U.S.A.) Inc. Carbonate diester solutions of PGE-type compounds
US4358603A (en) * 1981-04-16 1982-11-09 Syntex (U.S.A.) Inc. Acetal stabilized prostaglandin compositions
US4409239A (en) * 1982-01-21 1983-10-11 Syntex (U.S.A.) Inc. Propylene glycol diester solutions of PGE-type compounds
US4600785A (en) * 1983-12-22 1986-07-15 Syntex (U.S.A.) Inc. Processes and intermediates for making 16-phenoxy and 16-substituted phenoxy-prostatrienoic acid derivatives
US4912235A (en) * 1983-12-22 1990-03-27 Syntex (U.S.A.) Inc. Processes and intermediates for making 16-phenoxy- and 16-substituted phenoxy-prostatrienoic acid derivatives and their stereoisomers
US4804787A (en) * 1983-12-22 1989-02-14 Syntex (U.S.A.) Inc. Processes and intermediates for making 16-phenoxy and 16-substituted phenoxy-prostatrienoic acid derivatives
DE3414509A1 (de) * 1984-04-13 1985-10-24 Schering AG, 1000 Berlin und 4709 Bergkamen Neue 9-halogen-prostaglandine
US5057621A (en) * 1984-07-31 1991-10-15 Syntex (U.S.A.) Inc. 11-substituted-16-phenoxy and 16-substituted phenoxy-prostatrienoic acid derivatives
US4618696A (en) * 1984-07-31 1986-10-21 Syntex (U.S.A.) Inc. 9-oxo-15α-hydroxy-16-phenoxy and 16-substituted phenoxy 17,18,19,20-tetranorprosta-4,5,13,(E)-trienoates
ZA855740B (en) * 1984-07-31 1987-03-25 Syntex Inc 11-substituted-16-phenoxy and 16-substituted phenoxy-prostatrienoic acid derivatives
US4792617A (en) * 1984-07-31 1988-12-20 Syntex (U.S.A.) Inc. 11-substituted-16-phenoxy and 16-substituted phenoxy-prostatrienioc acid derivatives
US4778904A (en) * 1985-09-13 1988-10-18 Syntex (U.S.A.) Inc. Intermediates for making 16-phenoxy- and 16-(substituted phenoxy)-prostatrienoic acid derivatives
DK185987A (da) * 1986-04-11 1987-10-12 Syntex Inc Anvendelse af prostaglandiner
US4755531A (en) * 1986-08-11 1988-07-05 Syntex (U.S.A.) Inc. Thiol esters of 4,5-allenyl prostaglandins and use thereof as antigastric secretion agents
GB8625321D0 (en) * 1986-10-22 1986-11-26 Glaxo Group Ltd Chemical compounds
US4689419A (en) * 1986-11-14 1987-08-25 G. D. Searle & Co. Novel intermediate compounds in a process for producing 16-phenoxy- and 16-substituted phenoxy-9-keto-prostatrienoic acid derivatives
US6103765A (en) 1997-07-09 2000-08-15 Androsolutions, Inc. Methods for treating male erectile dysfunction
KR20010021625A (ko) 1997-07-09 2001-03-15 추후보정 개선된 남성발기 기능장애 치료방법 및 그 조성물
US20020013294A1 (en) 2000-03-31 2002-01-31 Delong Mitchell Anthony Cosmetic and pharmaceutical compositions and methods using 2-decarboxy-2-phosphinico derivatives
US20020037914A1 (en) 2000-03-31 2002-03-28 Delong Mitchell Anthony Compositions and methods for treating hair loss using C16-C20 aromatic tetrahydro prostaglandins
US20020172693A1 (en) 2000-03-31 2002-11-21 Delong Michell Anthony Compositions and methods for treating hair loss using non-naturally occurring prostaglandins
US8966971B2 (en) * 2008-07-28 2015-03-03 Ford Global Technologies, Llc Vehicle engine with fluid measuring system
US8722739B2 (en) 2008-10-29 2014-05-13 Novaer Holdings, Inc. Amino acid salts of prostaglandins
US8623918B2 (en) 2008-10-29 2014-01-07 Novaer Holdings, Inc. Amino acid salts of prostaglandins
EP2349242B1 (en) * 2008-10-29 2018-12-05 Novaer Holdings, Inc. Amino acid salts of prostaglandins
US20110293549A1 (en) 2009-02-03 2011-12-01 Athena Cosmetics, Inc. Composition, method and kit for enhancing hair

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES449162A1 (es) * 1975-06-23 1977-12-16 Syntex Inc Un procedimiento para la preparacion de un compuesto racemi-co u 8r-antimerico.

Also Published As

Publication number Publication date
GB2025413A (en) 1980-01-23
FR2430939A1 (fr) 1980-02-08
IT1121462B (it) 1986-04-02
JPS5513282A (en) 1980-01-30
AU4864179A (en) 1980-02-07
NO152296C (no) 1985-09-04
PL217001A1 (no) 1980-03-24
PL120632B1 (en) 1982-03-31
FR2430939B1 (no) 1981-08-14
JPS6210227B2 (no) 1987-03-05
HU184185B (en) 1984-07-30
KR890002773B1 (ko) 1989-07-28
DE2927715A1 (de) 1980-01-24
MY8500576A (en) 1985-12-31
DK288879A (da) 1980-01-11
DK157753C (da) 1990-07-09
NO152212C (no) 1985-08-21
YU73586A (en) 1986-12-31
YU73686A (en) 1986-12-31
NO792283L (no) 1980-01-11
NZ190924A (en) 1980-11-28
YU41870B (en) 1988-02-29
NO152211B (no) 1985-05-13
PL120633B1 (en) 1982-03-31
AU527516B2 (en) 1983-03-10
GB2025413B (en) 1982-07-28
FI69061C (fi) 1985-12-10
IT7968428A0 (it) 1979-07-09
YU44553B (en) 1990-08-31
SG82483G (en) 1984-08-03
US4178457A (en) 1979-12-11
EP0008003B1 (en) 1983-02-09
NO840257L (no) 1980-01-11
DE2964709D1 (en) 1983-03-17
NO152211C (no) 1985-08-21
DE2927715C2 (no) 1987-08-27
FI792149A (fi) 1980-01-11
SU1031407A3 (ru) 1983-07-23
NO150836B (no) 1984-09-17
ES482330A1 (es) 1980-08-16
EP0008003A1 (en) 1980-02-20
NO840258L (no) 1980-01-11
DD146179A5 (de) 1981-01-28
CS209927B2 (en) 1981-12-31
FI69061B (fi) 1985-08-30
NO152212B (no) 1985-05-13
ATE2427T1 (de) 1983-03-15
CA1149802A (en) 1983-07-12
NO150836C (no) 1985-01-09
YU168579A (en) 1983-02-28
HK41384A (en) 1984-05-18
DK157753B (da) 1990-02-12
NO152296B (no) 1985-05-28
YU44554B (en) 1990-08-31
PL121778B1 (en) 1982-05-31
NO840256L (no) 1980-01-11
PL120604B1 (en) 1982-03-31

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