ZA756185B - Improvements relating to 2,6-disubstituted 2-phenylimino imidazolidines - Google Patents

Improvements relating to 2,6-disubstituted 2-phenylimino imidazolidines

Info

Publication number
ZA756185B
ZA756185B ZA756185A ZA756185A ZA756185B ZA 756185 B ZA756185 B ZA 756185B ZA 756185 A ZA756185 A ZA 756185A ZA 756185 A ZA756185 A ZA 756185A ZA 756185 B ZA756185 B ZA 756185B
Authority
ZA
South Africa
Prior art keywords
imidazolidines
phenylimino
disubstituted
improvements relating
relating
Prior art date
Application number
ZA756185A
Other languages
English (en)
Inventor
H Staehle
W Hoefke
H Koeppe
W Kummer
Original Assignee
Boehringer Sohn Ingelheim
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Sohn Ingelheim filed Critical Boehringer Sohn Ingelheim
Publication of ZA756185B publication Critical patent/ZA756185B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/44—Nitrogen atoms not forming part of a nitro radical
    • C07D233/50—Nitrogen atoms not forming part of a nitro radical with carbocyclic radicals directly attached to said nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
ZA756185A 1974-10-01 1975-09-30 Improvements relating to 2,6-disubstituted 2-phenylimino imidazolidines ZA756185B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2446758A DE2446758C3 (de) 1974-10-01 1974-10-01 2-(2-Fluor-6-trifluormethylphenylimino)-imidazolidin, dessen Säureadditionssalze, Verfahren zur Herstellung dieser Verbindungen und deren Verwendung bei der Bekämpfung der Hypertonie

Publications (1)

Publication Number Publication Date
ZA756185B true ZA756185B (en) 1977-06-29

Family

ID=5927202

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA756185A ZA756185B (en) 1974-10-01 1975-09-30 Improvements relating to 2,6-disubstituted 2-phenylimino imidazolidines

Country Status (27)

Country Link
JP (1) JPS6018653B2 (pl)
AT (1) AT344159B (pl)
BE (1) BE834051A (pl)
BG (2) BG25220A3 (pl)
CA (1) CA1056836A (pl)
CH (5) CH620682A5 (pl)
CS (1) CS193524B2 (pl)
DD (1) DD123602A5 (pl)
DE (1) DE2446758C3 (pl)
DK (1) DK441875A (pl)
ES (4) ES441385A1 (pl)
FI (1) FI61883C (pl)
FR (1) FR2286649A1 (pl)
GB (1) GB1515019A (pl)
HU (1) HU178469B (pl)
IE (1) IE42130B1 (pl)
IL (1) IL48214A (pl)
LU (1) LU73472A1 (pl)
NL (1) NL7511490A (pl)
NO (1) NO143459C (pl)
NZ (1) NZ178810A (pl)
PH (1) PH13653A (pl)
PL (2) PL97003B1 (pl)
SE (1) SE418497B (pl)
SU (1) SU575026A3 (pl)
YU (1) YU230281A (pl)
ZA (1) ZA756185B (pl)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2630060C2 (de) * 1976-07-03 1984-04-19 C.H. Boehringer Sohn, 6507 Ingelheim 2-(2-Brom-6-fluor-phenylimino)-imidazolidin, dessen Säureadditionssalze, diese enthaltende Arzneimittel und Verfahren zu deren Herstellung
DE2806775A1 (de) * 1978-02-17 1979-08-30 Boehringer Sohn Ingelheim Neue substituierte 2-phenylimino- imidazolidine deren saeureadditionssalze, diese enthaltende arzneimittel und verfahren zur herstellung derselben
DE2806811A1 (de) * 1978-02-17 1979-08-23 Boehringer Sohn Ingelheim Neue substituierte 2-phenylimino- imidazolidine, deren saeureadditionssalze, diese enthaltene arzneimittel und verfahren zur herstellung derselben
ZA801680B (en) * 1979-04-03 1981-03-25 Fujisawa Pharmaceutical Co 2-imidazoline derivatives,process for the preparation thereof and the pharmaceutical composition of the same
HU192986B (en) 1984-05-23 1987-08-28 Egyt Gyogyszervegyeszeti Gyar Process for production of imidasodiline derivatives
CA2637292A1 (en) * 2006-01-27 2007-08-16 F. Hoffmann-La Roche Ag Use of 2-imidazoles for the treatment of cns disorders
JP5248528B2 (ja) 2007-02-02 2013-07-31 エフ．ホフマン−ラ ロシュ アーゲー Ｃｎｓ疾患用のｔａａｒ１リガンドとしての新規２−アミノオキサゾリン
CA2676944C (en) 2007-02-15 2016-01-19 F. Hoffmann-La Roche Ag 2-aminooxazolines as taar1 ligands
US8242153B2 (en) 2008-07-24 2012-08-14 Hoffmann-La Roche Inc. 4,5-dihydro-oxazol-2YL derivatives
US8354441B2 (en) 2009-11-11 2013-01-15 Hoffmann-La Roche Inc. Oxazoline derivatives
US9452980B2 (en) 2009-12-22 2016-09-27 Hoffmann-La Roche Inc. Substituted benzamides
SG11201807516UA (en) 2016-03-17 2018-09-27 Hoffmann La Roche 5-ethyl-4-methyl-pyrazole-3-carboxamide derivative having activity as agonist of taar

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3236857A (en) * 1961-10-09 1966-02-22 Boehringer Sohn Ingelheim 2-(phenyl-amino)-1, 3-diazacyclopentene-(2) substitution products
DE1670807A1 (de) * 1967-02-17 1971-03-11 Bayer Ag Verfahren zur Herstellung von cyclischen Guanidinen
DE1670918A1 (de) * 1967-09-07 1971-04-08 Bayer Ag Verfahren zur Herstellung von 2-Aryl-amino-substituierten stickstoffhaltigen Heterocyclen
BE787683A (fr) * 1971-08-20 1973-02-19 Boehringer Sohn Ingelheim 2-phenylimino-imidazolidines, leurs sels d'addition avec des acides et procedes pour les fabriquer

Also Published As

Publication number Publication date
DD123602A5 (pl) 1977-01-05
FR2286649A1 (fr) 1976-04-30
FR2286649B1 (pl) 1979-09-14
IE42130L (en) 1976-04-01
ES441385A1 (es) 1977-08-01
CH627454A5 (en) 1982-01-15
BE834051A (fr) 1976-03-30
ES444898A1 (es) 1977-05-16
FI61883C (fi) 1982-10-11
FI752728A (pl) 1976-04-02
JPS5159863A (en) 1976-05-25
DE2446758C3 (de) 1979-01-04
NZ178810A (en) 1978-04-03
CS193524B2 (en) 1979-10-31
DE2446758A1 (de) 1976-04-22
PL97003B1 (pl) 1978-01-31
ATA722875A (de) 1977-11-15
CH627453A5 (en) 1982-01-15
NO143459C (no) 1981-02-18
CH627452A5 (en) 1982-01-15
AU8529875A (en) 1977-04-07
BG25221A3 (en) 1978-08-10
IL48214A0 (en) 1975-11-25
SE418497B (sv) 1981-06-09
JPS6018653B2 (ja) 1985-05-11
PL98984B1 (pl) 1978-06-30
BG25220A3 (en) 1978-08-10
FI61883B (fi) 1982-06-30
YU230281A (en) 1982-02-28
NO753314L (pl) 1976-04-02
CH626352A5 (en) 1981-11-13
ES444900A1 (es) 1977-04-16
IE42130B1 (en) 1980-06-04
CA1056836A (en) 1979-06-19
DE2446758B2 (de) 1978-05-18
ES444901A1 (es) 1977-04-16
GB1515019A (en) 1978-06-21
SU575026A3 (ru) 1977-09-30
PH13653A (en) 1980-08-21
HU178469B (en) 1982-05-28
DK441875A (da) 1976-04-02
SE7511028L (sv) 1976-04-02
NO143459B (no) 1980-11-10
IL48214A (en) 1979-10-31
NL7511490A (nl) 1976-04-05
AT344159B (de) 1978-07-10
LU73472A1 (pl) 1977-05-16
CH620682A5 (en) 1980-12-15

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