ZA708590B - Isoquinoline derivatives - Google Patents

Isoquinoline derivatives

Info

Publication number
ZA708590B
ZA708590B ZA708590A ZA708590A ZA708590B ZA 708590 B ZA708590 B ZA 708590B ZA 708590 A ZA708590 A ZA 708590A ZA 708590 A ZA708590 A ZA 708590A ZA 708590 B ZA708590 B ZA 708590B
Authority
ZA
South Africa
Prior art keywords
isoquinoline derivatives
isoquinoline
derivatives
Prior art date
Application number
ZA708590A
Other languages
English (en)
Inventor
A Rheiner
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of ZA708590B publication Critical patent/ZA708590B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/18—Aralkyl radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/14—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
ZA708590A 1970-01-06 1970-12-21 Isoquinoline derivatives ZA708590B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH10370A CH527194A (de) 1970-01-06 1970-01-06 Verfahren zur Herstellung von Isochinolin-Derivaten

Publications (1)

Publication Number Publication Date
ZA708590B true ZA708590B (en) 1971-09-29

Family

ID=4179328

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA708590A ZA708590B (en) 1970-01-06 1970-12-21 Isoquinoline derivatives

Country Status (19)

Country Link
JP (1) JPS5515476B1 (no)
AT (1) AT303041B (no)
BE (1) BE761219A (no)
CA (1) CA999866A (no)
CH (2) CH527194A (no)
DE (1) DE2062001C2 (no)
DK (1) DK125021B (no)
ES (1) ES387016A1 (no)
FI (1) FI49503C (no)
FR (1) FR2081412B1 (no)
GB (1) GB1335261A (no)
IE (1) IE34859B1 (no)
IL (1) IL35916A (no)
NL (1) NL171444C (no)
NO (1) NO135315C (no)
PH (1) PH9682A (no)
SE (3) SE386672B (no)
YU (1) YU33660B (no)
ZA (1) ZA708590B (no)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA844402B (en) * 1983-06-23 1986-01-29 Mcneil Pharmaceutical Hexahydropyrrolo(2,1-a)isoquinoline derivatives
US4719216A (en) * 1983-06-23 1988-01-12 Mcneilab, Inc. Hexahydropyrrolo(2,1-A)isoquinoline derivatives as antidepressants
US4595688A (en) * 1983-06-23 1986-06-17 Mcneilab, Inc. Hexahydropyrrolo[2,1-a]isoquinoline derivatives and antidepressant use thereof
GB2271566A (en) * 1992-10-14 1994-04-20 Merck & Co Inc HIV integrase inhibitors
AU784280B2 (en) * 1999-11-03 2006-03-02 Albany Molecular Research, Inc. 4-phenyl-substituted tetrahydroisoquinolines and use thereof to block reuptake of norepinephrine, dopamine and serotonin
US7163949B1 (en) * 1999-11-03 2007-01-16 Amr Technology, Inc. 4-phenyl substituted tetrahydroisoquinolines and use thereof
KR100885986B1 (ko) 1999-11-03 2009-03-03 에이엠알 테크놀로지, 인크. 노르에피네프린, 도파민 및 세로토닌의 재흡수를 방지하기위한 아릴 및 헤테로아릴 치환된테트라하이드로이소퀴놀린 및 이들의 용도
EP1113007A1 (en) 1999-12-24 2001-07-04 Pfizer Inc. Tetrahydroisoquinoline compounds as estrogen agonists/antagonists
NZ523456A (en) 2000-07-11 2004-11-26 Albany Molecular Res Inc Novel 4-phenyl substituted tetrahydroisoquinolines and therapeutic use thereof
KR101389246B1 (ko) 2004-07-15 2014-04-24 브리스톨-마이어스스퀴브컴파니 아릴- 및 헤테로아릴-치환된 테트라히드로이소퀴놀린, 및 이것의 노르에피네프린, 도파민 및 세로토닌의 재흡수를 차단하기 위한 용도
ES2314933T3 (es) * 2005-06-17 2009-03-16 Janssen Pharmaceutica Nv Compuestos de naftiridina.
JP5258561B2 (ja) 2005-07-15 2013-08-07 アルバニー モレキュラー リサーチ， インコーポレイテッド アリール置換およびヘテロアリール置換テトラヒドロベンズアゼピンならびにノルエピネフリン、ドーパミンおよびセロトニンの再取り込みを遮断するためのその使用
US9156812B2 (en) 2008-06-04 2015-10-13 Bristol-Myers Squibb Company Crystalline form of 6-[(4S)-2-methyl-4-(2-naphthyl)-1,2,3,4-tetrahydroisoquinolin-7-yl]pyridazin-3-amine
AR071997A1 (es) 2008-06-04 2010-07-28 Bristol Myers Squibb Co Forma cristalina de 6-((4s)-2-metil-4-(2-naftil)-1,2,3,4-tetrahidroisoquinolin-7-il)piridazin-3-amina
AU2010247763B2 (en) 2009-05-12 2015-12-24 Albany Molecular Research, Inc. 7-([1,2,4,]triazolo[1,5,-a]pyridin-6-yl)-4-(3,4-dichlorophenyl)-1,2,3,4- tetrahydroisoquinoline and use thereof
ES2528404T3 (es) 2009-05-12 2015-02-10 Bristol-Myers Squibb Company Formas cristalinas de (S)-7-([1,2,4]triazol[1,5-a]piridin-6-il)-4-(3,4-diclorofenil)-1,2,3,4-tetrahidroisoquinolina y sus usos
AU2010247849B2 (en) 2009-05-12 2015-11-19 Albany Molecular Research, Inc. Aryl, heteroaryl, and heterocycle substituted tetrahydroisoquinolines and use thereof

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1670694B2 (de) * 1966-05-05 1976-07-22 Hoechst Ag, 6000 Frankfurt Verfahren zur herstellung von tetrahydroisochinolinen

Also Published As

Publication number Publication date
SE368401B (no) 1974-07-01
GB1335261A (en) 1973-10-24
YU1971A (en) 1977-06-30
IE34859B1 (en) 1975-09-03
IL35916A0 (en) 1971-02-25
FR2081412B1 (no) 1974-04-12
SE386672B (sv) 1976-08-16
NO135315B (no) 1976-12-13
FI49503B (no) 1975-04-01
FR2081412A1 (no) 1971-12-03
NL171444B (nl) 1982-11-01
CA999866A (en) 1976-11-16
CH527194A (de) 1972-08-31
AT303041B (de) 1972-11-10
NO135315C (no) 1977-03-23
IE34859L (en) 1971-07-06
FI49503C (fi) 1975-07-10
IL35916A (en) 1973-11-28
JPS5515476B1 (no) 1980-04-23
CH538477A (de) 1973-06-30
BE761219A (fr) 1971-07-05
DE2062001C2 (de) 1986-10-16
PH9682A (en) 1976-02-10
NL7018956A (no) 1971-07-08
NL171444C (nl) 1983-04-05
DE2062001A1 (de) 1971-07-15
SE399879B (sv) 1978-03-06
DK125021B (da) 1972-12-18
ES387016A1 (es) 1976-05-01
YU33660B (en) 1977-12-31

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