BE761219A - Derives d'isoquinoleine - Google Patents

Derives d'isoquinoleine

Info

Publication number
BE761219A
BE761219A BE761219A BE761219A BE761219A BE 761219 A BE761219 A BE 761219A BE 761219 A BE761219 A BE 761219A BE 761219 A BE761219 A BE 761219A BE 761219 A BE761219 A BE 761219A
Authority
BE
Belgium
Prior art keywords
isoquinoleine
derivatives
isoquinoleine derivatives
Prior art date
Application number
BE761219A
Other languages
English (en)
French (fr)
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of BE761219A publication Critical patent/BE761219A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/18—Aralkyl radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/14—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
BE761219A 1970-01-06 1971-01-05 Derives d'isoquinoleine BE761219A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH10370A CH527194A (de) 1970-01-06 1970-01-06 Verfahren zur Herstellung von Isochinolin-Derivaten

Publications (1)

Publication Number Publication Date
BE761219A true BE761219A (fr) 1971-07-05

Family

ID=4179328

Family Applications (1)

Application Number Title Priority Date Filing Date
BE761219A BE761219A (fr) 1970-01-06 1971-01-05 Derives d'isoquinoleine

Country Status (19)

Country Link
JP (1) JPS5515476B1 (no)
AT (1) AT303041B (no)
BE (1) BE761219A (no)
CA (1) CA999866A (no)
CH (2) CH527194A (no)
DE (1) DE2062001C2 (no)
DK (1) DK125021B (no)
ES (1) ES387016A1 (no)
FI (1) FI49503C (no)
FR (1) FR2081412B1 (no)
GB (1) GB1335261A (no)
IE (1) IE34859B1 (no)
IL (1) IL35916A (no)
NL (1) NL171444C (no)
NO (1) NO135315C (no)
PH (1) PH9682A (no)
SE (3) SE368401B (no)
YU (1) YU33660B (no)
ZA (1) ZA708590B (no)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4719216A (en) * 1983-06-23 1988-01-12 Mcneilab, Inc. Hexahydropyrrolo(2,1-A)isoquinoline derivatives as antidepressants
US4595688A (en) * 1983-06-23 1986-06-17 Mcneilab, Inc. Hexahydropyrrolo[2,1-a]isoquinoline derivatives and antidepressant use thereof
ZA844402B (en) * 1983-06-23 1986-01-29 Mcneil Pharmaceutical Hexahydropyrrolo(2,1-a)isoquinoline derivatives
GB2271566A (en) * 1992-10-14 1994-04-20 Merck & Co Inc HIV integrase inhibitors
KR100878855B1 (ko) * 1999-11-03 2009-01-15 에이엠알 테크놀로지, 인크. 4-페닐-치환 테트라히드로이소퀴놀린, 및 노르에피네프린과 도파민과 세로토닌의 재흡수를 차단하기 위한 이의 용도
US7163949B1 (en) * 1999-11-03 2007-01-16 Amr Technology, Inc. 4-phenyl substituted tetrahydroisoquinolines and use thereof
ES2304984T3 (es) 1999-11-03 2008-11-01 Amr Technology, Inc. Tetra-hidroisoquinolinas de sustitucion arilica y heteroarilica y su utilizacion para bloquear la recaptacion de norepinefrina, dopamina y serotonina.
EP1113007A1 (en) 1999-12-24 2001-07-04 Pfizer Inc. Tetrahydroisoquinoline compounds as estrogen agonists/antagonists
CA2415532C (en) 2000-07-11 2010-05-11 Albany Molecular Research, Inc. Novel 4-phenyl substituted tetrahydroisoquinolines therapeutic use thereof
JP5007226B2 (ja) 2004-07-15 2012-08-22 エーエムアール テクノロジー インコーポレイテッド アリールおよびヘテロアリール置換テトラヒドロイソキノリンならびにノルエピネフリン、ドーパミン、およびセロトニンの再取り込みを遮断するためのその利用方法
EP1899334B1 (en) 2005-06-17 2008-09-24 Janssen Pharmaceutica N.V. Naphthyridine compounds
KR101589551B1 (ko) 2005-07-15 2016-02-02 알바니 몰레큘라 리써치, 인크. 아릴- 및 헤테로아릴-치환된 테트라히드로벤자제핀, 및 노르에피네프린, 도파민 및 세로토닌의 재흡수를 차단하기 위한 용도
US9156812B2 (en) 2008-06-04 2015-10-13 Bristol-Myers Squibb Company Crystalline form of 6-[(4S)-2-methyl-4-(2-naphthyl)-1,2,3,4-tetrahydroisoquinolin-7-yl]pyridazin-3-amine
AR071997A1 (es) 2008-06-04 2010-07-28 Bristol Myers Squibb Co Forma cristalina de 6-((4s)-2-metil-4-(2-naftil)-1,2,3,4-tetrahidroisoquinolin-7-il)piridazin-3-amina
CN102458123A (zh) 2009-05-12 2012-05-16 阿尔巴尼分子研究公司 芳基、杂芳基和杂环取代的四氢异喹啉及其用途
JP5739415B2 (ja) 2009-05-12 2015-06-24 ブリストル−マイヤーズ スクウィブ カンパニー （Ｓ）−７−（［１，２，４］トリアゾロ［１，５−ａ］ピリジン−６−イル）−４−（３，４−ジクロロフェニル）−１，２，３，４−テトラヒドロイソキノリンの結晶形態およびその使用
KR101830447B1 (ko) 2009-05-12 2018-02-20 알바니 몰레큘라 리써치, 인크. 7-(［1,2,4］트리아졸로［1,5-α］피리딘-6-일)-4-(3,4-디클로로페닐)-1,2,3,4-테트라하이드로이소퀴놀린 및 이의 용도

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1670694B2 (de) * 1966-05-05 1976-07-22 Hoechst Ag, 6000 Frankfurt Verfahren zur herstellung von tetrahydroisochinolinen

Also Published As

Publication number Publication date
NL171444C (nl) 1983-04-05
SE368401B (no) 1974-07-01
JPS5515476B1 (no) 1980-04-23
NO135315C (no) 1977-03-23
SE386672B (sv) 1976-08-16
IE34859L (en) 1971-07-06
DE2062001C2 (de) 1986-10-16
IL35916A (en) 1973-11-28
YU1971A (en) 1977-06-30
YU33660B (en) 1977-12-31
DK125021B (da) 1972-12-18
ES387016A1 (es) 1976-05-01
FI49503C (fi) 1975-07-10
FR2081412B1 (no) 1974-04-12
PH9682A (en) 1976-02-10
CA999866A (en) 1976-11-16
DE2062001A1 (de) 1971-07-15
IL35916A0 (en) 1971-02-25
GB1335261A (en) 1973-10-24
NL7018956A (no) 1971-07-08
IE34859B1 (en) 1975-09-03
FI49503B (no) 1975-04-01
FR2081412A1 (no) 1971-12-03
SE399879B (sv) 1978-03-06
AT303041B (de) 1972-11-10
CH538477A (de) 1973-06-30
NL171444B (nl) 1982-11-01
NO135315B (no) 1976-12-13
ZA708590B (en) 1971-09-29
CH527194A (de) 1972-08-31

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Legal Events

Date Code Title Description
RE Patent lapsed

Owner name: F. HOFFMANN-LA ROCHE & CIE S.A.

Effective date: 19880131