ZA201007524B - Purine pi3k inhibitor compounds and methods of use - Google Patents

Purine pi3k inhibitor compounds and methods of use

Info

Publication number
ZA201007524B
ZA201007524B ZA2010/07524A ZA201007524A ZA201007524B ZA 201007524 B ZA201007524 B ZA 201007524B ZA 2010/07524 A ZA2010/07524 A ZA 2010/07524A ZA 201007524 A ZA201007524 A ZA 201007524A ZA 201007524 B ZA201007524 B ZA 201007524B
Authority
ZA
South Africa
Prior art keywords
purine
methods
inhibitor compounds
pi3k inhibitor
pi3k
Prior art date
Application number
ZA2010/07524A
Other languages
English (en)
Inventor
Georgette Castanedo
Irina Chuckowree
Adrian FOLKES
Daniel P Sutherlin
Nan Chi Wan
Original Assignee
Genentech Inc
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech Inc, Hoffmann La Roche filed Critical Genentech Inc
Publication of ZA201007524B publication Critical patent/ZA201007524B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
    • C07D473/32—Nitrogen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ZA2010/07524A 2008-05-30 2010-10-21 Purine pi3k inhibitor compounds and methods of use ZA201007524B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US5755908P 2008-05-30 2008-05-30
PCT/US2009/045603 WO2009146406A1 (en) 2008-05-30 2009-05-29 Purine pi3k inhibitor compounds and methods of use

Publications (1)

Publication Number Publication Date
ZA201007524B true ZA201007524B (en) 2012-01-25

Family

ID=41017038

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA2010/07524A ZA201007524B (en) 2008-05-30 2010-10-21 Purine pi3k inhibitor compounds and methods of use

Country Status (14)

Country Link
US (2) US8158624B2 (enExample)
EP (1) EP2279188B1 (enExample)
JP (1) JP2011521968A (enExample)
KR (1) KR20110042153A (enExample)
CN (1) CN102105474B (enExample)
AU (1) AU2009251291B2 (enExample)
BR (1) BRPI0909614A2 (enExample)
CA (1) CA2721851A1 (enExample)
ES (1) ES2533788T3 (enExample)
IL (1) IL208838A0 (enExample)
MX (1) MX2010012583A (enExample)
RU (1) RU2509081C2 (enExample)
WO (1) WO2009146406A1 (enExample)
ZA (1) ZA201007524B (enExample)

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Also Published As

Publication number Publication date
US20090318411A1 (en) 2009-12-24
IL208838A0 (en) 2011-01-31
EP2279188B1 (en) 2015-01-28
BRPI0909614A2 (pt) 2015-09-22
AU2009251291A1 (en) 2009-12-03
JP2011521968A (ja) 2011-07-28
RU2509081C2 (ru) 2014-03-10
CN102105474A (zh) 2011-06-22
CA2721851A1 (en) 2009-12-03
US20120135988A1 (en) 2012-05-31
CN102105474B (zh) 2014-01-08
US8158624B2 (en) 2012-04-17
US8445487B2 (en) 2013-05-21
ES2533788T3 (es) 2015-04-14
WO2009146406A1 (en) 2009-12-03
RU2010154428A (ru) 2012-07-10
AU2009251291B2 (en) 2013-05-02
EP2279188A1 (en) 2011-02-02
MX2010012583A (es) 2011-02-24
KR20110042153A (ko) 2011-04-25

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