AU2009251291B2 - Purine PI3K inhibitor compounds and methods of use - Google Patents

Purine PI3K inhibitor compounds and methods of use Download PDF

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Publication number
AU2009251291B2
AU2009251291B2 AU2009251291A AU2009251291A AU2009251291B2 AU 2009251291 B2 AU2009251291 B2 AU 2009251291B2 AU 2009251291 A AU2009251291 A AU 2009251291A AU 2009251291 A AU2009251291 A AU 2009251291A AU 2009251291 B2 AU2009251291 B2 AU 2009251291B2
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AU
Australia
Prior art keywords
purin
morpholino
methyl
carcinoma
aminopyrimidin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU2009251291A
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English (en)
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AU2009251291A1 (en
Inventor
Georgette Castanedo
Irina Chuckowree
Adrian Folkes
Daniel P. Sutherlin
Nan Chi Wan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Genentech Inc
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F Hoffmann La Roche AG
Genentech Inc
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Publication of AU2009251291A1 publication Critical patent/AU2009251291A1/en
Application granted granted Critical
Publication of AU2009251291B2 publication Critical patent/AU2009251291B2/en
Ceased legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
    • C07D473/32—Nitrogen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU2009251291A 2008-05-30 2009-05-29 Purine PI3K inhibitor compounds and methods of use Ceased AU2009251291B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US5755908P 2008-05-30 2008-05-30
US61/057,559 2008-05-30
PCT/US2009/045603 WO2009146406A1 (en) 2008-05-30 2009-05-29 Purine pi3k inhibitor compounds and methods of use

Publications (2)

Publication Number Publication Date
AU2009251291A1 AU2009251291A1 (en) 2009-12-03
AU2009251291B2 true AU2009251291B2 (en) 2013-05-02

Family

ID=41017038

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2009251291A Ceased AU2009251291B2 (en) 2008-05-30 2009-05-29 Purine PI3K inhibitor compounds and methods of use

Country Status (14)

Country Link
US (2) US8158624B2 (enExample)
EP (1) EP2279188B1 (enExample)
JP (1) JP2011521968A (enExample)
KR (1) KR20110042153A (enExample)
CN (1) CN102105474B (enExample)
AU (1) AU2009251291B2 (enExample)
BR (1) BRPI0909614A2 (enExample)
CA (1) CA2721851A1 (enExample)
ES (1) ES2533788T3 (enExample)
IL (1) IL208838A0 (enExample)
MX (1) MX2010012583A (enExample)
RU (1) RU2509081C2 (enExample)
WO (1) WO2009146406A1 (enExample)
ZA (1) ZA201007524B (enExample)

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JP6701088B2 (ja) 2014-03-19 2020-05-27 インフィニティー ファーマシューティカルズ， インコーポレイテッド Ｐｉ３ｋ−ガンマ媒介障害の治療で使用するための複素環式化合物
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Also Published As

Publication number Publication date
RU2010154428A (ru) 2012-07-10
CN102105474B (zh) 2014-01-08
BRPI0909614A2 (pt) 2015-09-22
MX2010012583A (es) 2011-02-24
US20090318411A1 (en) 2009-12-24
ES2533788T3 (es) 2015-04-14
KR20110042153A (ko) 2011-04-25
US8445487B2 (en) 2013-05-21
JP2011521968A (ja) 2011-07-28
US20120135988A1 (en) 2012-05-31
IL208838A0 (en) 2011-01-31
CA2721851A1 (en) 2009-12-03
EP2279188B1 (en) 2015-01-28
EP2279188A1 (en) 2011-02-02
US8158624B2 (en) 2012-04-17
ZA201007524B (en) 2012-01-25
CN102105474A (zh) 2011-06-22
AU2009251291A1 (en) 2009-12-03
RU2509081C2 (ru) 2014-03-10
WO2009146406A1 (en) 2009-12-03

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