ES2533788T3 - Compuestos inhibidores de PI3K de tipo purina y métodos de uso - Google Patents

Compuestos inhibidores de PI3K de tipo purina y métodos de uso Download PDF

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Publication number
ES2533788T3
ES2533788T3 ES09755767.2T ES09755767T ES2533788T3 ES 2533788 T3 ES2533788 T3 ES 2533788T3 ES 09755767 T ES09755767 T ES 09755767T ES 2533788 T3 ES2533788 T3 ES 2533788T3
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ES
Spain
Prior art keywords
morpholino
purin
alkylene
methyl
heterocyclyl
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Active
Application number
ES09755767.2T
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English (en)
Spanish (es)
Inventor
Georgette Castanedo
Irina Chuckowree
Adrian Folkes
Daniel P. Sutherlin
Nan Chi Wan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Genentech Inc
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F Hoffmann La Roche AG
Genentech Inc
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
    • C07D473/32—Nitrogen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ES09755767.2T 2008-05-30 2009-05-29 Compuestos inhibidores de PI3K de tipo purina y métodos de uso Active ES2533788T3 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US57559 1987-06-03
US5755908P 2008-05-30 2008-05-30
PCT/US2009/045603 WO2009146406A1 (en) 2008-05-30 2009-05-29 Purine pi3k inhibitor compounds and methods of use

Publications (1)

Publication Number Publication Date
ES2533788T3 true ES2533788T3 (es) 2015-04-14

Family

ID=41017038

Family Applications (1)

Application Number Title Priority Date Filing Date
ES09755767.2T Active ES2533788T3 (es) 2008-05-30 2009-05-29 Compuestos inhibidores de PI3K de tipo purina y métodos de uso

Country Status (14)

Country Link
US (2) US8158624B2 (enExample)
EP (1) EP2279188B1 (enExample)
JP (1) JP2011521968A (enExample)
KR (1) KR20110042153A (enExample)
CN (1) CN102105474B (enExample)
AU (1) AU2009251291B2 (enExample)
BR (1) BRPI0909614A2 (enExample)
CA (1) CA2721851A1 (enExample)
ES (1) ES2533788T3 (enExample)
IL (1) IL208838A0 (enExample)
MX (1) MX2010012583A (enExample)
RU (1) RU2509081C2 (enExample)
WO (1) WO2009146406A1 (enExample)
ZA (1) ZA201007524B (enExample)

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CN105209466B (zh) * 2013-05-02 2018-05-18 豪夫迈·罗氏有限公司 作为cb2受体激动剂的嘌呤衍生物
TW201520215A (zh) * 2013-05-13 2015-06-01 Daiichi Sankyo Co Ltd Ｎ－□啉基嘌呤衍生物之製造方法
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CN103804380B (zh) * 2014-01-24 2016-05-18 温州医科大学 以IKK-β为靶点的2-氨基-8-取代鸟嘌呤衍生物、应用及其制备方法
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Also Published As

Publication number Publication date
ZA201007524B (en) 2012-01-25
AU2009251291A1 (en) 2009-12-03
WO2009146406A1 (en) 2009-12-03
CN102105474A (zh) 2011-06-22
US8445487B2 (en) 2013-05-21
RU2010154428A (ru) 2012-07-10
US20090318411A1 (en) 2009-12-24
KR20110042153A (ko) 2011-04-25
EP2279188A1 (en) 2011-02-02
AU2009251291B2 (en) 2013-05-02
CN102105474B (zh) 2014-01-08
RU2509081C2 (ru) 2014-03-10
CA2721851A1 (en) 2009-12-03
BRPI0909614A2 (pt) 2015-09-22
IL208838A0 (en) 2011-01-31
US8158624B2 (en) 2012-04-17
JP2011521968A (ja) 2011-07-28
EP2279188B1 (en) 2015-01-28
MX2010012583A (es) 2011-02-24
US20120135988A1 (en) 2012-05-31

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