ZA200602755B - Modulators of ATP-binding cassette transporters - Google Patents

Modulators of ATP-binding cassette transporters Download PDF

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Publication number
ZA200602755B
ZA200602755B ZA200602755A ZA200602755A ZA200602755B ZA 200602755 B ZA200602755 B ZA 200602755B ZA 200602755 A ZA200602755 A ZA 200602755A ZA 200602755 A ZA200602755 A ZA 200602755A ZA 200602755 B ZA200602755 B ZA 200602755B
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South Africa
Prior art keywords
aliphatic
optionally substituted
ors
phenyl
ring
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ZA200602755A
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English (en)
Inventor
Mark T Miller
Ruah Sara S Hadida
Ashavini K Singh
Cleveland Thomas
Lewis R Markings
Hamilton Matthew
Peter D J Grootenhuis
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Vertex Pharma
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Publication of ZA200602755B publication Critical patent/ZA200602755B/en

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    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
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ZA200602755A 2003-09-06 2004-09-07 Modulators of ATP-binding cassette transporters ZA200602755B (en)

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EP (1) EP1664006A2 (https=)
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KR (1) KR20060088537A (https=)
CN (1) CN1898221A (https=)
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UA80295C2 (en) 2002-09-06 2007-09-10 Biogen Inc Pyrazolopyridines and using the same
TW200519106A (en) 2003-05-02 2005-06-16 Novartis Ag Organic compounds
RU2006111093A (ru) 2003-09-06 2007-10-27 Вертекс Фармасьютикалз Инкорпорейтед (Us) Модуляторы атр-связывающих кассетных транспортеров
CN101675928A (zh) * 2003-11-14 2010-03-24 沃泰克斯药物股份有限公司 可用作atp-结合弹夹转运蛋白调控剂的噻唑和噁唑
CA2551611C (en) * 2003-12-26 2013-06-25 Kyowa Kirin Co., Ltd. Thiazole derivatives for treating or preventing parkinson's disease
US7977322B2 (en) 2004-08-20 2011-07-12 Vertex Pharmaceuticals Incorporated Modulators of ATP-binding cassette transporters
US7384968B2 (en) * 2004-04-01 2008-06-10 Pfizer Inc. Thiazole-amine compounds for the treatment of neurodegenerative disorders
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