ZA200406730B - Indazole substituted with an anti-cancerous activity. - Google Patents

Indazole substituted with an anti-cancerous activity. Download PDF

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Publication number
ZA200406730B
ZA200406730B ZA200406730A ZA200406730A ZA200406730B ZA 200406730 B ZA200406730 B ZA 200406730B ZA 200406730 A ZA200406730 A ZA 200406730A ZA 200406730 A ZA200406730 A ZA 200406730A ZA 200406730 B ZA200406730 B ZA 200406730B
Authority
ZA
South Africa
Prior art keywords
indazol
benzenesulfonamide
phenyl
methanesulfonyl
substituted
Prior art date
Application number
ZA200406730A
Other languages
English (en)
Inventor
Dominique Damour
Patrick Nemecek
Frederico Nardi
Marie-Pierre Cherrier
Jean-Christophe Carry
Corine Terrier
Bruno Filoche
Daniel Bezard
Original Assignee
Aventis Pharma Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Sa filed Critical Aventis Pharma Sa
Publication of ZA200406730B publication Critical patent/ZA200406730B/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/54—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings condensed with carbocyclic rings or ring systems
    • C07D231/56—Benzopyrazoles; Hydrogenated benzopyrazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond

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  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Cosmetics (AREA)
ZA200406730A 2002-03-11 2004-08-24 Indazole substituted with an anti-cancerous activity. ZA200406730B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0202996A FR2836914B1 (fr) 2002-03-11 2002-03-11 Indazoles substitues, compositions les contenant, procede de fabrication et utilisation

Publications (1)

Publication Number Publication Date
ZA200406730B true ZA200406730B (en) 2005-08-24

Family

ID=27763684

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200406730A ZA200406730B (en) 2002-03-11 2004-08-24 Indazole substituted with an anti-cancerous activity.

Country Status (29)

Country Link
US (2) US6858638B2 (https=)
EP (1) EP1487803A1 (https=)
JP (1) JP4643910B2 (https=)
KR (1) KR20040091128A (https=)
CN (1) CN100369899C (https=)
AR (1) AR038914A1 (https=)
AU (1) AU2003242808B2 (https=)
BR (1) BR0308339A (https=)
CA (1) CA2478540A1 (https=)
EC (1) ECSP045286A (https=)
FR (1) FR2836914B1 (https=)
GT (1) GT200300031A (https=)
HN (1) HN2003000094A (https=)
HR (1) HRP20040825A2 (https=)
IL (2) IL163805A0 (https=)
MA (1) MA27176A1 (https=)
MX (1) MXPA04008446A (https=)
NO (1) NO20044261L (https=)
OA (1) OA12784A (https=)
PA (1) PA8566701A1 (https=)
PE (1) PE20040071A1 (https=)
PL (1) PL372389A1 (https=)
RU (1) RU2004130280A (https=)
SV (1) SV2003001493A (https=)
TN (1) TNSN04175A1 (https=)
TW (1) TW200303863A (https=)
UY (1) UY27712A1 (https=)
WO (1) WO2003078402A1 (https=)
ZA (1) ZA200406730B (https=)

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WO2011050245A1 (en) * 2009-10-23 2011-04-28 Yangbo Feng Bicyclic heteroaryls as kinase inhibitors
CN102247361B (zh) * 2010-05-20 2015-04-29 中国医学科学院药物研究所 5-硝基-1氢-吲唑-3-腈在制备药物中的应用
UA113500C2 (xx) 2010-10-29 2017-02-10 Одержані екструзією розплаву тверді дисперсії, що містять індукуючий апоптоз засіб
CA3152557A1 (en) 2010-10-29 2012-05-03 Abbvie Inc. Solid dispersions containing an apoptosis-inducing agent
PT2643322T (pt) 2010-11-23 2017-11-13 Abbvie Inc Sais e formas cristalinas de um agente indutor de apoptose
ES2603129T3 (es) 2010-11-23 2017-02-23 Abbvie Ireland Unlimited Company Métodos de tratamiento utilizando inhibidores selectivos de Bcl-2
US20140275082A1 (en) 2013-03-14 2014-09-18 Abbvie Inc. Apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseases
WO2016071293A2 (en) 2014-11-03 2016-05-12 Iomet Pharma Ltd Pharmaceutical compound
GB201511382D0 (en) 2015-06-29 2015-08-12 Imp Innovations Ltd Novel compounds and their use in therapy
US11926596B2 (en) 2017-07-21 2024-03-12 Kadmon Corporation, Llc Inhibitors of Rho associated coiled-coil containing protein kinase
US11186549B2 (en) 2017-08-29 2021-11-30 Rutgers, The State University Of New Jersey Therapeutic indazoles
IL310724A (en) 2021-08-10 2024-04-01 Ifm Due Inc COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF CONDITIONS ASSOCIATED WITH STING ACTIVITY
CN118715205A (zh) * 2022-01-12 2024-09-27 艾福姆德尤股份有限公司 用于治疗与sting活性相关的病症的化合物和组合物
CN116693519A (zh) 2022-03-04 2023-09-05 上海璎黎药业有限公司 一种含五元杂芳环结构化合物、其药物组合物及应用
CN114605329B (zh) * 2022-03-28 2024-01-26 河南中医药大学 取代的吲唑甲酰胺或取代的氮杂吲唑甲酰胺类flt3抑制剂及其用途
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Also Published As

Publication number Publication date
OA12784A (fr) 2006-07-10
UY27712A1 (es) 2003-09-30
MA27176A1 (fr) 2005-01-03
HN2003000094A (es) 2003-12-15
ECSP045286A (es) 2004-10-26
HRP20040825A2 (en) 2005-06-30
RU2004130280A (ru) 2005-06-27
US6858638B2 (en) 2005-02-22
US20040106667A1 (en) 2004-06-03
PA8566701A1 (es) 2003-12-10
FR2836914B1 (fr) 2008-03-14
EP1487803A1 (fr) 2004-12-22
IL163805A (en) 2009-08-03
BR0308339A (pt) 2005-02-01
US20050059722A1 (en) 2005-03-17
MXPA04008446A (es) 2004-12-06
NO20044261L (no) 2004-11-25
PL372389A1 (en) 2005-07-25
CN1642922A (zh) 2005-07-20
PE20040071A1 (es) 2004-02-13
JP4643910B2 (ja) 2011-03-02
SV2003001493A (es) 2003-07-10
JP2005533004A (ja) 2005-11-04
AU2003242808A1 (en) 2003-09-29
IL163805A0 (en) 2005-12-18
CA2478540A1 (fr) 2003-09-25
TW200303863A (en) 2003-09-16
WO2003078402A1 (fr) 2003-09-25
GT200300031A (es) 2006-05-26
CN100369899C (zh) 2008-02-20
AU2003242808B2 (en) 2008-09-18
KR20040091128A (ko) 2004-10-27
US7473701B2 (en) 2009-01-06
FR2836914A1 (fr) 2003-09-12
AR038914A1 (es) 2005-02-02
TNSN04175A1 (fr) 2007-03-12

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