ZA200400406B - Novel cyclohexyl sulphones. - Google Patents

Novel cyclohexyl sulphones. Download PDF

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Publication number
ZA200400406B
ZA200400406B ZA200400406A ZA200400406A ZA200400406B ZA 200400406 B ZA200400406 B ZA 200400406B ZA 200400406 A ZA200400406 A ZA 200400406A ZA 200400406 A ZA200400406 A ZA 200400406A ZA 200400406 B ZA200400406 B ZA 200400406B
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South Africa
Prior art keywords
pharmaceutically acceptable
compound according
halogen
acceptable salt
amino
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ZA200400406A
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English (en)
Inventor
Ian Churcher
Timothy Harrison
Nadin Alan John
Shaw Duncan Edward
Williams Brian John
Kevin Dinnell
Sonia Kerrad
Oakley Paul Joseph
Teall Martin Richard
Susannah Williams
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Merck Sharp & Dohme
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Publication of ZA200400406B publication Critical patent/ZA200400406B/en

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    • C07D271/02—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
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    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
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    • C07D285/02—Thiadiazoles; Hydrogenated thiadiazoles
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    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/096—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
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    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182—Radicals derived from carboxylic acids
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ZA200400406A 2001-08-21 2004-01-20 Novel cyclohexyl sulphones. ZA200400406B (en)

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AR047666A1 (es) * 2004-02-20 2006-02-01 Merck Sharp & Dohme Sintesis estereoselectiva del acido ciclohexanopropanoico 4,4-disubstituido
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US20060041020A1 (en) 2006-02-23
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CN1545501A (zh) 2004-11-10
RS51296B (sr) 2010-12-31
BR0211635A (pt) 2004-07-13
DE60223692D1 (en) 2008-01-03
PT1421062E (pt) 2008-01-23
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US6984663B2 (en) 2006-01-10
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US7304094B2 (en) 2007-12-04
RS8504A (en) 2007-02-05
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KR20040027961A (ko) 2004-04-01
US20080045533A1 (en) 2008-02-21
CY1107116T1 (el) 2012-10-24
AR036215A1 (es) 2004-08-18
TWI328573B (en) 2010-08-11
KR100908993B1 (ko) 2009-07-22
US20030114496A1 (en) 2003-06-19
DE60223692T2 (de) 2008-10-30
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