ZA200306370B - Heterocyclic compounds for aging-related and diabetic vascular complications. - Google Patents

Heterocyclic compounds for aging-related and diabetic vascular complications. Download PDF

Info

Publication number
ZA200306370B
ZA200306370B ZA200306370A ZA200306370A ZA200306370B ZA 200306370 B ZA200306370 B ZA 200306370B ZA 200306370 A ZA200306370 A ZA 200306370A ZA 200306370 A ZA200306370 A ZA 200306370A ZA 200306370 B ZA200306370 B ZA 200306370B
Authority
ZA
South Africa
Prior art keywords
pyrazol
oxoethyl
acceptable salt
pharmaceutically acceptable
methyl
Prior art date
Application number
ZA200306370A
Other languages
English (en)
Inventor
Alangudi Sankaranarayanan
Original Assignee
Torrent Pharmaceuticals Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Torrent Pharmaceuticals Ltd filed Critical Torrent Pharmaceuticals Ltd
Publication of ZA200306370B publication Critical patent/ZA200306370B/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10Drugs for genital or sexual disorders; Contraceptives for impotence
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/10Anti-acne agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/16Emollients or protectives, e.g. against radiation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/12Ophthalmic agents for cataracts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00General protective or antinoxious agents
    • A61P39/06Free radical scavengers or antioxidants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06Antianaemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
ZA200306370A 2001-04-05 2003-08-15 Heterocyclic compounds for aging-related and diabetic vascular complications. ZA200306370B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US28138001P 2001-04-05 2001-04-05

Publications (1)

Publication Number Publication Date
ZA200306370B true ZA200306370B (en) 2004-06-07

Family

ID=23077044

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200306370A ZA200306370B (en) 2001-04-05 2003-08-15 Heterocyclic compounds for aging-related and diabetic vascular complications.

Country Status (22)

Country Link
US (2) US7223777B2 (hu)
EP (1) EP1373263B1 (hu)
JP (2) JP4485744B2 (hu)
KR (1) KR100785109B1 (hu)
CN (1) CN1259316C (hu)
AT (1) ATE280766T1 (hu)
AU (1) AU2002253432B2 (hu)
BR (1) BR0208561A (hu)
CA (1) CA2439593C (hu)
CZ (1) CZ20032013A3 (hu)
DE (1) DE60201740T2 (hu)
DK (1) DK1373263T3 (hu)
ES (1) ES2231685T3 (hu)
HK (1) HK1061234A1 (hu)
HU (1) HUP0400823A3 (hu)
MX (1) MXPA03008089A (hu)
PL (1) PL365441A1 (hu)
PT (1) PT1373263E (hu)
RU (1) RU2291154C2 (hu)
SI (1) SI1373263T1 (hu)
WO (1) WO2002085897A1 (hu)
ZA (1) ZA200306370B (hu)

Families Citing this family (54)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1355645A4 (en) * 2000-12-29 2005-02-23 Alteon Inc METHOD FOR THE TREATMENT OF FIBROUS OR OTHER IIIC INDICATIONS
HUP0400823A3 (en) * 2001-04-05 2010-06-28 Torrent Pharmaceuticals Ltd Heterocyclic compounds for treating aging-related and diabetic vascular complications, their preparation and pharmaceutical compositions containing them
CN100436445C (zh) * 2003-02-07 2008-11-26 第一制药株式会社 吡唑衍生物
PL377848A1 (pl) 2003-02-07 2006-02-20 Daiichi Pharmaceutical Co., Ltd. Pochodne pirazoli
EP1669348A4 (en) 2003-09-30 2009-03-11 Eisai R&D Man Co Ltd NEW ANTIPILIC AGENT CONTAINING A HETEROCYCLIC COMPOUND
US7354938B2 (en) * 2004-03-23 2008-04-08 Amgen Inc. Pyrazole compounds and uses related thereto
US20050241110A1 (en) * 2004-04-09 2005-11-03 Bruce Baker Ergonomic handles, especially for garden tools
WO2006002983A1 (en) * 2004-07-06 2006-01-12 Novartis Ag Combination of organic compounds
US20090227799A1 (en) * 2004-08-09 2009-09-10 Kazutaka Nakamoto Novel Antimalarial Agent Containing Heterocyclic Compound
WO2006033943A2 (en) 2004-09-17 2006-03-30 Exelixis, Inc Pyrazole kinase modulators and methods of use
WO2006069063A1 (en) 2004-12-20 2006-06-29 Genentech, Inc. Pyrrolidine inhibitors of iap
WO2006091761A1 (en) * 2005-02-24 2006-08-31 University Of Washington Methods for treatment of retinal degenerative disease
EP1864980A4 (en) 2005-03-30 2010-08-18 Eisai R&D Man Co Ltd A PYRIDINE DERIVATIVE ANTIPILIC AGENT
KR101003569B1 (ko) 2005-10-31 2010-12-22 에자이 알앤드디 매니지먼트 가부시키가이샤 헤테로환 치환 피리딘 유도체 및 이들을 함유하는 항진균제
CN101300250B (zh) * 2005-10-31 2012-09-05 卫材R&D管理有限公司 杂环取代吡啶衍生物及含有该衍生物的抗真菌剂
TWI385169B (zh) 2005-10-31 2013-02-11 Eisai R&D Man Co Ltd 經雜環取代之吡啶衍生物及含有彼之抗真菌劑
SA07280004B1 (ar) 2006-02-02 2011-10-29 استرازينيكا ايه بي ملح سترات من مركب 2- هيدروكسي –3- [5- (مورفولين –4- يل ميثيل) بيريدين –2- يل] 1h- إندول –5- كربونيتريل سترات
AU2007270814B2 (en) 2006-07-05 2011-07-14 Pfizer Products Inc. Pyrazole derivatives as cytochrome P450 inhibitors
WO2008035726A1 (fr) 2006-09-21 2008-03-27 Eisai R & D Management Co., Ltd. Dérivé de pyridine substitué par un cycle hétéroaryle, et agent antifongique le comprenant
ES2421326T3 (es) 2006-11-29 2013-08-30 Abbvie Inc. Inhibidores de la enzima diacilglicerol O-aciltransferasa de tipo 1
US20090197819A1 (en) * 2007-03-20 2009-08-06 Clarence Albert Johnson Compositions for improving and repairing skin
US20080312169A1 (en) * 2007-03-20 2008-12-18 Clarence Albert Johnson Cosmetic use of D-ribose
CN102702185A (zh) 2007-04-27 2012-10-03 卫材R&D管理有限公司 杂环取代吡啶衍生物的盐的结晶
TW200841879A (en) 2007-04-27 2008-11-01 Eisai R&D Man Co Ltd Pyridine derivatives substituted by heterocyclic ring and phosphonoamino group, and anti-fungal agent containing same
KR20100024923A (ko) 2007-04-30 2010-03-08 제넨테크, 인크. Iap의 억제제
FR2918570B1 (fr) * 2007-07-09 2012-10-05 Engelhard Lyon DIGLYCATION DES AGEs.
WO2009042542A1 (en) * 2007-09-26 2009-04-02 Indiana University Research And Technology Corporation Benzoquinone derivative e3330 in combination with chemotherapeutic agents for the treatment of cancer and angiogenesis
US8410277B2 (en) 2007-12-26 2013-04-02 Eisai R&D Managment Co., Ltd. Method for manufacturing heterocycle substituted pyridine derivatives
US8513287B2 (en) 2007-12-27 2013-08-20 Eisai R&D Management Co., Ltd. Heterocyclic ring and phosphonoxymethyl group substituted pyridine derivatives and antifungal agent containing same
KR100989093B1 (ko) 2008-01-18 2010-10-25 한화제약주식회사 생강나무 가지의 추출물을 포함하는 심혈관계 질환의 예방 및 치료용 조성물
RU2010135524A (ru) * 2008-01-25 2012-02-27 Торрент Фармасьютикалз Лтд. (In) Фармацевтические комбинации
US20090232750A1 (en) * 2008-03-13 2009-09-17 St Cyr John A Compositions for indoor tanning
EP2318395A4 (en) 2008-08-02 2011-10-26 Genentech Inc IPA INHIBITORS
EP2345328A4 (en) * 2008-09-19 2014-06-25 Sumitomo Chemical Co COMPOSITION FOR USE IN AGRICULTURE
CN102186477B (zh) * 2008-10-16 2013-07-17 奥梅-杨森制药有限公司 作为代谢型谷氨酸受体调节剂的吲哚和苯并吗啉衍生物
US8188119B2 (en) 2008-10-24 2012-05-29 Eisai R&D Management Co., Ltd Pyridine derivatives substituted with heterocyclic ring and γ-glutamylamino group, and antifungal agents containing same
EP2427432A2 (en) 2009-05-07 2012-03-14 Torrent Pharmaceuticals Limited Novel heterocyclic compounds
KR101040162B1 (ko) * 2009-05-12 2011-06-09 주식회사 카모스 감시카메라의 브라켓
WO2011051198A2 (de) 2009-10-30 2011-05-05 Bayer Cropscience Ag Pyridin-derivate als pflanzenschutzmittel
KR101018881B1 (ko) * 2009-11-03 2011-03-04 주식회사 엑스트론아이앤티 감시카메라용 브라켓
CN102858748B (zh) * 2010-04-28 2015-06-17 东丽株式会社 阿尔茨海默病的治疗剂或预防剂
WO2012020738A1 (ja) * 2010-08-09 2012-02-16 武田薬品工業株式会社 複素環化合物およびその用途
SI2968249T1 (sl) 2013-02-22 2019-04-30 Samumed, Llc Gama-diketoni kot aktivatorji signalne poti Wnt/beta-katenin
US9226890B1 (en) 2013-12-10 2016-01-05 Englewood Lab, Llc Polysilicone base for scar treatment
EP3145923B1 (en) * 2014-05-22 2019-01-30 F. Hoffmann-La Roche AG Indolin-2-one and 1,3-dihydro-pyrrolo[3,2-c]pyridin-2-one derivatives
CN107106549B (zh) 2014-08-20 2020-06-16 萨穆梅德有限公司 用于治疗和预防老化皮肤和皱纹的γ–二酮
FR3026947B1 (fr) * 2014-10-10 2017-12-08 Basf Beauty Care Solutions France Sas Activite deglycation d'une combinaison d'un extrait de salvia miltiorrhiza et de niacine et/ou de niacinamide
MX2017012943A (es) 2015-04-08 2018-01-30 Torrent Pharmaceuticals Ltd Nuevos compuestos de piridinio.
CN106806886B (zh) * 2015-12-01 2021-07-16 华中科技大学 一种快速消除口臭的口气清新剂及其医药用途
CN111698989B (zh) 2017-12-07 2023-08-01 安普利克斯制药公司 杂环取代的吡啶衍生物抗真菌剂
CN108157405B (zh) * 2018-02-06 2020-10-02 上海应用技术大学 一种灭蟑螂饵剂及其制备方法和应用
WO2020005860A1 (en) * 2018-06-25 2020-01-02 Amplyx Pharmaceuticals, Inc. Pyridine derivatives substituted by heterocyclic ring and amino group
EP3886854A4 (en) 2018-11-30 2022-07-06 Nuvation Bio Inc. PYRROLE AND PYRAZOLE COMPOUNDS AND METHODS OF USE THERE
DE202022104072U1 (de) 2022-07-19 2022-07-29 Siva Subramanian Narayanasamy Heterozyklisch substituierte pyridinderivate antimykotische Mittel

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3501484A (en) * 1968-01-15 1970-03-17 Miles Lab Certain substituted 3 - (2-indolyl)-1,2,5,6-tetrahydropyridines and derivatives thereof
US3501312A (en) * 1968-07-22 1970-03-17 Eastman Kodak Co Direct positive silver halide emulsions containing trimethine cyanine dyes
US3957805A (en) * 1974-07-24 1976-05-18 American Cyanamid Company Substituted pyridines and diazines and methods of preparing the same
US5514676A (en) 1984-03-19 1996-05-07 The Rockefeller University Amino-benzoic acids and derivatives, and methods of use
US5272176A (en) * 1984-03-19 1993-12-21 The Rockefeller University Advanced glycation inhibitors containing amino-benzoic acids and derivatives, and methods of use
US4758583A (en) 1984-03-19 1988-07-19 The Rockefeller University Method and agents for inhibiting protein aging
US5137916A (en) 1985-11-14 1992-08-11 The Rockefeller University Advanced glycation inhibitors containing amino-benzoic acids and derivatives, and methods of use
GB8714789D0 (en) * 1987-06-24 1987-07-29 Lundbeck & Co As H Heterocyclic compounds
EP0339496A3 (en) 1988-04-26 1991-05-08 Ono Pharmaceutical Co., Ltd. Aminoguanidine derivatives
US5330994A (en) * 1992-03-24 1994-07-19 Warner-Lambert Company Tetrahydropyridine isoxazoline derivatives
DE4210502A1 (de) * 1992-03-31 1993-10-07 Bayer Ag Verwendung von 3-aminosubstituierten Isoxazolderivaten zur Bekämpfung von Endoparasiten, neue 3-aminosubstituierte Isoxazolderivate und Verfahren zu ihrer Herstellung
US5656261A (en) 1995-01-18 1997-08-12 The Picower Institute For Medical Research Preventing and reversing advanced glycosylation endproducts
DE69629176T2 (de) 1995-01-18 2004-06-03 Alteon Inc. Verwendung von thiazoliumverbindungen zum verhindern und umkehren der bildung von endprodukten der fortgeschrittenen glykosylierung
US6228858B1 (en) * 1995-09-12 2001-05-08 University Of Kansas Medical Center Advanced glycation end-product intermediaries and post-amadori inhibition
JPH09291082A (ja) * 1996-02-27 1997-11-11 Sankyo Co Ltd イソキサゾール誘導体
AU7553198A (en) * 1997-06-12 1998-12-30 Sumitomo Pharmaceuticals Company, Limited Pyrazole derivatives
AU3512400A (en) * 1999-03-05 2000-09-21 Kansas University Medical Center Novel post-amadori inhibitors of advanced glycation reactions
US20010044445A1 (en) * 1999-04-08 2001-11-22 Bamaung Nwe Y. Azole inhibitors of cytokine production
WO2000066101A2 (en) * 1999-04-30 2000-11-09 City Of Hope Method of inhibiting glycation product formation
FR2796278B1 (fr) 1999-07-16 2002-05-03 Oreal Utilisation d'au moins un hydroxystilbene comme agent anti-glycation
HU227523B1 (en) * 1999-10-06 2011-07-28 Torrent Pharmaceuticals Ltd Pyridinium derivatives for the management of aging-related and diabetic vascular complications, process for their preparation and therapeutic uses thereof
CA2351075A1 (en) * 1999-10-06 2001-04-12 Torrent Pharmaceuticals Ltd. Pyridinium derivatives for the treatment of diabetic and aging-related vascular complications
FR2802420B1 (fr) 1999-12-21 2002-02-22 Oreal Utilisation du 3,3', 5,5'-tetrahydroxystilbene comme agent anti-glycation
HUP0400823A3 (en) * 2001-04-05 2010-06-28 Torrent Pharmaceuticals Ltd Heterocyclic compounds for treating aging-related and diabetic vascular complications, their preparation and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
ES2231685T3 (es) 2005-05-16
AU2002253432B2 (en) 2005-03-24
JP2004529154A (ja) 2004-09-24
CN1498217A (zh) 2004-05-19
BR0208561A (pt) 2004-03-30
ATE280766T1 (de) 2004-11-15
DE60201740T2 (de) 2005-11-03
PL365441A1 (en) 2005-01-10
KR20030086340A (ko) 2003-11-07
WO2002085897A1 (en) 2002-10-31
US20070167493A1 (en) 2007-07-19
KR100785109B1 (ko) 2007-12-12
JP2010100640A (ja) 2010-05-06
HUP0400823A2 (hu) 2004-07-28
WO2002085897A9 (en) 2004-04-01
WO2002085897A8 (en) 2002-11-28
SI1373263T1 (en) 2005-04-30
US7223777B2 (en) 2007-05-29
HK1061234A1 (en) 2004-09-10
DK1373263T3 (da) 2005-03-07
RU2003128076A (ru) 2005-04-10
HUP0400823A3 (en) 2010-06-28
US20030045554A1 (en) 2003-03-06
MXPA03008089A (es) 2004-01-22
RU2291154C2 (ru) 2007-01-10
EP1373263A1 (en) 2004-01-02
PT1373263E (pt) 2005-03-31
EP1373263B1 (en) 2004-10-27
CN1259316C (zh) 2006-06-14
CA2439593A1 (en) 2002-10-31
JP4485744B2 (ja) 2010-06-23
CA2439593C (en) 2010-02-09
DE60201740D1 (de) 2004-12-02
CZ20032013A3 (cs) 2003-12-17

Similar Documents

Publication Publication Date Title
ZA200306370B (en) Heterocyclic compounds for aging-related and diabetic vascular complications.
AU2002253432A1 (en) Heterocyclic compounds for aging-related and diabetic vascular complications
KR20080055874A (ko) 당뇨병 치료용 디펩티딜 펩티다아제 억제제
WO2005044192A2 (en) Triazole compounds and uses related thereto
JP2002535256A (ja) 化合物および方法
JP4068843B2 (ja) 老化関連及び糖尿病性血管合併症の管理のためのピリジニウム誘導体、それらの製造方法並びにそれらの治療的使用
EP1304101A1 (en) Composition and method for use of pyridinium derivatives in cosmetic and therapeutic applications
JPH07500811A (ja) アミノ置換ピリミジン、その誘導体及びその使用方法
MXPA02003496A (es) Derivados de piridinio para el tratamiento de complicaciones vasculares diabeticas y relacionadas con la edad.
US6608094B2 (en) Compounds for the management of aging-related and diabetic vascular complications, process for their preparation and therapeutic uses thereof
US20020103228A1 (en) Composition and method for use of pyridinium derivatives in cosmetic and therapeutic applications
JP4471141B2 (ja) 老化関連及び糖尿病脈管合併症の管理のための新規化合物、その製造方法及び治療的使用
US20010018524A1 (en) Novel compounds for the management of aging-related and diabetic vascular complications, process for their preparation and therapeutic uses thereof
JP2002515033A (ja) 置換イミダゾリウム塩、及びタンパク質老化を阻止するためのそれらの使用
WO2015003625A1 (zh) 噻唑内盐类化合物、其制备方法及用途
JP2014070051A (ja) ニペコチン酸誘導体及びその医薬用途
AU8936901A (en) Composition and method for use of pyridinium derivatives in cosmetic and therapeutic applications
MXPA06004674A (en) Triazole compounds and uses related thereto