PT1373263E - Compostos heterociclicos para complicacoes relacionadas com a idade e complicacoes vasculares diabeticas - Google Patents

Compostos heterociclicos para complicacoes relacionadas com a idade e complicacoes vasculares diabeticas

Info

Publication number
PT1373263E
PT1373263E PT02722547T PT02722547T PT1373263E PT 1373263 E PT1373263 E PT 1373263E PT 02722547 T PT02722547 T PT 02722547T PT 02722547 T PT02722547 T PT 02722547T PT 1373263 E PT1373263 E PT 1373263E
Authority
PT
Portugal
Prior art keywords
age
complications
discloses
compounds
diabetic vascular
Prior art date
Application number
PT02722547T
Other languages
English (en)
Inventor
Sankaranarayanan Alangudi
Original Assignee
Torrent Pharmaceuticals Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Torrent Pharmaceuticals Ltd filed Critical Torrent Pharmaceuticals Ltd
Publication of PT1373263E publication Critical patent/PT1373263E/pt

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10Drugs for genital or sexual disorders; Contraceptives for impotence
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/10Anti-acne agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/16Emollients or protectives, e.g. against radiation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/12Ophthalmic agents for cataracts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00General protective or antinoxious agents
    • A61P39/06Free radical scavengers or antioxidants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06Antianaemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
PT02722547T 2001-04-05 2002-04-02 Compostos heterociclicos para complicacoes relacionadas com a idade e complicacoes vasculares diabeticas PT1373263E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US28138001P 2001-04-05 2001-04-05

Publications (1)

Publication Number Publication Date
PT1373263E true PT1373263E (pt) 2005-03-31

Family

ID=23077044

Family Applications (1)

Application Number Title Priority Date Filing Date
PT02722547T PT1373263E (pt) 2001-04-05 2002-04-02 Compostos heterociclicos para complicacoes relacionadas com a idade e complicacoes vasculares diabeticas

Country Status (22)

Country Link
US (2) US7223777B2 (pt)
EP (1) EP1373263B1 (pt)
JP (2) JP4485744B2 (pt)
KR (1) KR100785109B1 (pt)
CN (1) CN1259316C (pt)
AT (1) ATE280766T1 (pt)
AU (1) AU2002253432B2 (pt)
BR (1) BR0208561A (pt)
CA (1) CA2439593C (pt)
CZ (1) CZ20032013A3 (pt)
DE (1) DE60201740T2 (pt)
DK (1) DK1373263T3 (pt)
ES (1) ES2231685T3 (pt)
HK (1) HK1061234A1 (pt)
HU (1) HUP0400823A3 (pt)
MX (1) MXPA03008089A (pt)
PL (1) PL365441A1 (pt)
PT (1) PT1373263E (pt)
RU (1) RU2291154C2 (pt)
SI (1) SI1373263T1 (pt)
WO (1) WO2002085897A1 (pt)
ZA (1) ZA200306370B (pt)

Families Citing this family (54)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002067851A2 (en) * 2000-12-29 2002-09-06 Alteon, Inc. Method for treating fibrotic diseases or other indications iiic
SI1373263T1 (en) * 2001-04-05 2005-04-30 Torrent Pharmaceuticals Ltd Heterocyclic compounds for aging-related and diabetic vascular complications
ZA200505734B (en) * 2003-02-07 2006-12-27 Daiichi Seiyaku Co Pyrazole Derivative
CA2515119A1 (en) 2003-02-07 2004-08-19 Daiichi Pharmaceutical Co., Ltd. Pyrazole derivative
US7932272B2 (en) 2003-09-30 2011-04-26 Eisai R&D Management Co., Ltd. Antifungal agent containing heterocyclic compound
US7354938B2 (en) * 2004-03-23 2008-04-08 Amgen Inc. Pyrazole compounds and uses related thereto
US20050241110A1 (en) * 2004-04-09 2005-11-03 Bruce Baker Ergonomic handles, especially for garden tools
WO2006002983A1 (en) * 2004-07-06 2006-01-12 Novartis Ag Combination of organic compounds
JPWO2006016548A1 (ja) * 2004-08-09 2008-05-01 エーザイ・アール・アンド・ディー・マネジメント株式会社 ヘテロ環化合物を含有する新規な抗マラリア剤
AU2005287170B2 (en) 2004-09-17 2012-03-29 Exelixis, Inc Pyrazole kinase modulators and methods of use
ES2349110T5 (es) 2004-12-20 2013-11-27 Genentech, Inc. Inhibidores de IAP derivados de pirrolidina
EP1858499A4 (en) * 2005-02-24 2010-03-03 Univ Washington METHODS OF TREATING RETINAL DEGENERATIVE DISEASE
EP1864980A4 (en) 2005-03-30 2010-08-18 Eisai R&D Man Co Ltd A PYRIDINE DERIVATIVE ANTIPILIC AGENT
KR101003569B1 (ko) 2005-10-31 2010-12-22 에자이 알앤드디 매니지먼트 가부시키가이샤 헤테로환 치환 피리딘 유도체 및 이들을 함유하는 항진균제
CN101300250B (zh) * 2005-10-31 2012-09-05 卫材R&D管理有限公司 杂环取代吡啶衍生物及含有该衍生物的抗真菌剂
TWI385169B (zh) * 2005-10-31 2013-02-11 Eisai R&D Man Co Ltd 經雜環取代之吡啶衍生物及含有彼之抗真菌劑
SA07280004B1 (ar) 2006-02-02 2011-10-29 استرازينيكا ايه بي ملح سترات من مركب 2- هيدروكسي –3- [5- (مورفولين –4- يل ميثيل) بيريدين –2- يل] 1h- إندول –5- كربونيتريل سترات
CA2660031A1 (en) 2006-07-05 2008-01-10 Pfizer Products Inc. Pyrazole derivatives as cytochrome p450 inhibitors
WO2008035726A1 (fr) 2006-09-21 2008-03-27 Eisai R & D Management Co., Ltd. Dérivé de pyridine substitué par un cycle hétéroaryle, et agent antifongique le comprenant
CA2670736A1 (en) 2006-11-29 2008-06-05 Abbott Laboratories Inhibitors of diacylglycerol o-acyltransferase type 1 enzyme
US20090197819A1 (en) * 2007-03-20 2009-08-06 Clarence Albert Johnson Compositions for improving and repairing skin
US20080312169A1 (en) * 2007-03-20 2008-12-18 Clarence Albert Johnson Cosmetic use of D-ribose
AU2008246798A1 (en) 2007-04-27 2008-11-13 Eisai R&D Management Co., Ltd. Salt of heterocycle-substituted pyridine derivative or crystal thereof
TW200841879A (en) * 2007-04-27 2008-11-01 Eisai R&D Man Co Ltd Pyridine derivatives substituted by heterocyclic ring and phosphonoamino group, and anti-fungal agent containing same
KR20100024923A (ko) * 2007-04-30 2010-03-08 제넨테크, 인크. Iap의 억제제
FR2918570B1 (fr) * 2007-07-09 2012-10-05 Engelhard Lyon DIGLYCATION DES AGEs.
CA2700274C (en) * 2007-09-26 2017-08-22 Indiana University Research And Technology Corporation Quinone derivatives, pharmaceutical compositions, and uses thereof
CN101910159B (zh) * 2007-12-26 2013-06-19 卫材R&D管理有限公司 杂环取代吡啶衍生物的制备方法
US8513287B2 (en) 2007-12-27 2013-08-20 Eisai R&D Management Co., Ltd. Heterocyclic ring and phosphonoxymethyl group substituted pyridine derivatives and antifungal agent containing same
KR100989093B1 (ko) 2008-01-18 2010-10-25 한화제약주식회사 생강나무 가지의 추출물을 포함하는 심혈관계 질환의 예방 및 치료용 조성물
US20110034378A1 (en) * 2008-01-25 2011-02-10 Chaitanya Dutt Pharmaceutical Combinations Comprising Specified Age Breaker and Further Drugs, I.A. Antihypertensive Drugs, Antidiabetic Drugs Etc.
US20090232750A1 (en) * 2008-03-13 2009-09-17 St Cyr John A Compositions for indoor tanning
JP2011529962A (ja) 2008-08-02 2011-12-15 ジェネンテック, インコーポレイテッド Iapのインヒビター
US20110201649A1 (en) * 2008-09-19 2011-08-18 Sumitomo Chemical Company, Limited agricultural composition
EP2346505B1 (en) * 2008-10-16 2014-04-23 Janssen Pharmaceuticals, Inc. Indole and benzomorpholine derivatives as modulators of metabotropic glutamate receptors
US8188119B2 (en) 2008-10-24 2012-05-29 Eisai R&D Management Co., Ltd Pyridine derivatives substituted with heterocyclic ring and γ-glutamylamino group, and antifungal agents containing same
CA2764232A1 (en) 2009-05-07 2010-11-11 Torrent Pharmaceuticals Limited Novel heterocyclic compounds
KR101040162B1 (ko) * 2009-05-12 2011-06-09 주식회사 카모스 감시카메라의 브라켓
WO2011051198A2 (de) 2009-10-30 2011-05-05 Bayer Cropscience Ag Pyridin-derivate als pflanzenschutzmittel
KR101018881B1 (ko) * 2009-11-03 2011-03-04 주식회사 엑스트론아이앤티 감시카메라용 브라켓
BR122021002784B1 (pt) * 2010-04-28 2021-08-31 Toray Industries, Inc Agente terapêutico ou agente profilático para a doença de alzheimer
WO2012020738A1 (ja) * 2010-08-09 2012-02-16 武田薬品工業株式会社 複素環化合物およびその用途
PT2968249T (pt) 2013-02-22 2019-02-06 Samumed Llc Gama-dicetonas como ativadores da via de sinalização wnt/beta-catenina
US9226890B1 (en) 2013-12-10 2016-01-05 Englewood Lab, Llc Polysilicone base for scar treatment
WO2015177110A1 (en) * 2014-05-22 2015-11-26 F. Hoffmann-La Roche Ag INDOLIN-2-ONE AND 1,3-DIHYDRO-PYRROLO[3,2-c]PYRIDIN-2-ONE DERIVATIVES
US9795550B2 (en) 2014-08-20 2017-10-24 Samumed, Llc Gamma-diketones for treatment and prevention of aging skin and wrinkles
FR3026947B1 (fr) * 2014-10-10 2017-12-08 Basf Beauty Care Solutions France Sas Activite deglycation d'une combinaison d'un extrait de salvia miltiorrhiza et de niacine et/ou de niacinamide
AU2016245418B2 (en) 2015-04-08 2020-03-26 Torrent Pharmaceuticals Limited Novel pyridinium compounds
CN106806886B (zh) * 2015-12-01 2021-07-16 华中科技大学 一种快速消除口臭的口气清新剂及其医药用途
KR20200096941A (ko) 2017-12-07 2020-08-14 앰플릭스 파마슈티컬스, 인크. 헤테로사이클 치환된 피리딘 유도체 항진균제
CN108157405B (zh) * 2018-02-06 2020-10-02 上海应用技术大学 一种灭蟑螂饵剂及其制备方法和应用
KR20210023984A (ko) 2018-06-25 2021-03-04 앰플릭스 파마슈티컬스, 인크. 헤테로환형 고리 및 아미노기로 치환된 피리딘 유도체
CA3121202A1 (en) 2018-11-30 2020-06-04 Nuvation Bio Inc. Pyrrole and pyrazole compounds and methods of use thereof
DE202022104072U1 (de) 2022-07-19 2022-07-29 Siva Subramanian Narayanasamy Heterozyklisch substituierte pyridinderivate antimykotische Mittel

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3501484A (en) * 1968-01-15 1970-03-17 Miles Lab Certain substituted 3 - (2-indolyl)-1,2,5,6-tetrahydropyridines and derivatives thereof
US3501312A (en) * 1968-07-22 1970-03-17 Eastman Kodak Co Direct positive silver halide emulsions containing trimethine cyanine dyes
US3957805A (en) * 1974-07-24 1976-05-18 American Cyanamid Company Substituted pyridines and diazines and methods of preparing the same
US5272176A (en) 1984-03-19 1993-12-21 The Rockefeller University Advanced glycation inhibitors containing amino-benzoic acids and derivatives, and methods of use
US4758583A (en) 1984-03-19 1988-07-19 The Rockefeller University Method and agents for inhibiting protein aging
US5137916A (en) 1985-11-14 1992-08-11 The Rockefeller University Advanced glycation inhibitors containing amino-benzoic acids and derivatives, and methods of use
US5514676A (en) 1984-03-19 1996-05-07 The Rockefeller University Amino-benzoic acids and derivatives, and methods of use
GB8714789D0 (en) * 1987-06-24 1987-07-29 Lundbeck & Co As H Heterocyclic compounds
EP0339496A3 (en) 1988-04-26 1991-05-08 Ono Pharmaceutical Co., Ltd. Aminoguanidine derivatives
US5330994A (en) * 1992-03-24 1994-07-19 Warner-Lambert Company Tetrahydropyridine isoxazoline derivatives
DE4210502A1 (de) * 1992-03-31 1993-10-07 Bayer Ag Verwendung von 3-aminosubstituierten Isoxazolderivaten zur Bekämpfung von Endoparasiten, neue 3-aminosubstituierte Isoxazolderivate und Verfahren zu ihrer Herstellung
US5656261A (en) 1995-01-18 1997-08-12 The Picower Institute For Medical Research Preventing and reversing advanced glycosylation endproducts
MX9705449A (es) 1995-01-18 1998-02-28 Alteon Inc Uso de compuestos de tiazolio para evitar y revertir la formacion de productos finales de glicosilacion avanzada.
US6228858B1 (en) * 1995-09-12 2001-05-08 University Of Kansas Medical Center Advanced glycation end-product intermediaries and post-amadori inhibition
JPH09291082A (ja) * 1996-02-27 1997-11-11 Sankyo Co Ltd イソキサゾール誘導体
AU7553198A (en) * 1997-06-12 1998-12-30 Sumitomo Pharmaceuticals Company, Limited Pyrazole derivatives
AU3512400A (en) * 1999-03-05 2000-09-21 Kansas University Medical Center Novel post-amadori inhibitors of advanced glycation reactions
US20010044445A1 (en) * 1999-04-08 2001-11-22 Bamaung Nwe Y. Azole inhibitors of cytokine production
WO2000066101A2 (en) * 1999-04-30 2000-11-09 City Of Hope Method of inhibiting glycation product formation
FR2796278B1 (fr) 1999-07-16 2002-05-03 Oreal Utilisation d'au moins un hydroxystilbene comme agent anti-glycation
MXPA02003496A (es) * 1999-10-06 2005-06-20 Torrent Pharmaceuticals Ltd Derivados de piridinio para el tratamiento de complicaciones vasculares diabeticas y relacionadas con la edad.
JP4068843B2 (ja) * 1999-10-06 2008-03-26 トレント・ファーマシューティカルズ・リミテッド 老化関連及び糖尿病性血管合併症の管理のためのピリジニウム誘導体、それらの製造方法並びにそれらの治療的使用
FR2802420B1 (fr) 1999-12-21 2002-02-22 Oreal Utilisation du 3,3', 5,5'-tetrahydroxystilbene comme agent anti-glycation
SI1373263T1 (en) * 2001-04-05 2005-04-30 Torrent Pharmaceuticals Ltd Heterocyclic compounds for aging-related and diabetic vascular complications

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ATE280766T1 (de) 2004-11-15
PL365441A1 (en) 2005-01-10
CA2439593A1 (en) 2002-10-31
ZA200306370B (en) 2004-06-07
CN1259316C (zh) 2006-06-14
US7223777B2 (en) 2007-05-29
US20030045554A1 (en) 2003-03-06
MXPA03008089A (es) 2004-01-22
SI1373263T1 (en) 2005-04-30
JP2004529154A (ja) 2004-09-24
HUP0400823A3 (en) 2010-06-28
EP1373263A1 (en) 2004-01-02
HUP0400823A2 (hu) 2004-07-28
CZ20032013A3 (cs) 2003-12-17
RU2003128076A (ru) 2005-04-10
JP4485744B2 (ja) 2010-06-23
DE60201740D1 (de) 2004-12-02
ES2231685T3 (es) 2005-05-16
WO2002085897A1 (en) 2002-10-31
DK1373263T3 (da) 2005-03-07
WO2002085897A9 (en) 2004-04-01
AU2002253432B2 (en) 2005-03-24
DE60201740T2 (de) 2005-11-03
RU2291154C2 (ru) 2007-01-10
CA2439593C (en) 2010-02-09
HK1061234A1 (en) 2004-09-10
BR0208561A (pt) 2004-03-30
JP2010100640A (ja) 2010-05-06
EP1373263B1 (en) 2004-10-27
WO2002085897A8 (en) 2002-11-28
KR20030086340A (ko) 2003-11-07
CN1498217A (zh) 2004-05-19
US20070167493A1 (en) 2007-07-19
KR100785109B1 (ko) 2007-12-12

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