ZA200202411B - Controlled release compositions comprising nimesulide. - Google Patents
Controlled release compositions comprising nimesulide. Download PDFInfo
- Publication number
- ZA200202411B ZA200202411B ZA200202411A ZA200202411A ZA200202411B ZA 200202411 B ZA200202411 B ZA 200202411B ZA 200202411 A ZA200202411 A ZA 200202411A ZA 200202411 A ZA200202411 A ZA 200202411A ZA 200202411 B ZA200202411 B ZA 200202411B
- Authority
- ZA
- South Africa
- Prior art keywords
- composition
- nimesulide
- controlled release
- active drug
- release
- Prior art date
Links
- 229960000965 nimesulide Drugs 0.000 title claims description 51
- HYWYRSMBCFDLJT-UHFFFAOYSA-N nimesulide Chemical compound CS(=O)(=O)NC1=CC=C([N+]([O-])=O)C=C1OC1=CC=CC=C1 HYWYRSMBCFDLJT-UHFFFAOYSA-N 0.000 title claims description 50
- 239000000203 mixture Substances 0.000 title claims description 49
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Classifications
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5084—Mixtures of one or more drugs in different galenical forms, at least one of which being granules, microcapsules or (coated) microparticles according to A61K9/16 or A61K9/50, e.g. for obtaining a specific release pattern or for combining different drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/2853—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers, poly(lactide-co-glycolide)
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- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pain & Pain Management (AREA)
- General Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Rheumatology (AREA)
- Neurology (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN1297DE1999 | 1999-09-28 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA200202411B true ZA200202411B (en) | 2003-06-26 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA200202411A ZA200202411B (en) | 1999-09-28 | 2002-03-26 | Controlled release compositions comprising nimesulide. |
Country Status (26)
| Country | Link |
|---|---|
| US (2) | US20070128276A1 (de) |
| EP (1) | EP1218889B1 (de) |
| JP (2) | JP4359412B2 (de) |
| KR (1) | KR100621281B1 (de) |
| CN (2) | CN101804041A (de) |
| AP (1) | AP1954A (de) |
| AT (1) | ATE450865T1 (de) |
| AU (1) | AU774099B2 (de) |
| BG (1) | BG66093B1 (de) |
| BR (1) | BR0014383A (de) |
| CA (1) | CA2385890C (de) |
| CZ (1) | CZ20021076A3 (de) |
| DE (1) | DE60043447D1 (de) |
| DK (1) | DK1218889T3 (de) |
| ES (1) | ES2337547T3 (de) |
| HU (1) | HUP0204451A3 (de) |
| IL (2) | IL148864A0 (de) |
| MX (1) | MXPA02003321A (de) |
| NO (1) | NO20021540L (de) |
| NZ (1) | NZ518052A (de) |
| PT (1) | PT1218889E (de) |
| RS (1) | RS50303B (de) |
| RU (1) | RU2238087C2 (de) |
| UA (1) | UA80667C2 (de) |
| WO (1) | WO2001022791A2 (de) |
| ZA (1) | ZA200202411B (de) |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
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| JP2007522079A (ja) * | 2003-10-31 | 2007-08-09 | エラン ファーマ インターナショナル リミテッド | ニメスリド組成物 |
| WO2005079752A2 (en) * | 2004-02-11 | 2005-09-01 | Rubicon Research Private Limited | Controlled release pharmaceutical compositions with improved bioavailability |
| US20080153779A1 (en) * | 2005-02-01 | 2008-06-26 | Jun Liao | Gastric Retention and Controlled Release Delivery System |
| EP1906933A2 (de) * | 2005-07-20 | 2008-04-09 | Panacea Biotec Ltd. | Neue pharmazeutische dosierform mit modifizierter freisetzung von cyclooxygenase-enzym-hemmer |
| CN100346778C (zh) * | 2005-07-22 | 2007-11-07 | 海南康力元药业有限公司 | 尼美舒利缓释组合物 |
| AU2007242405A1 (en) * | 2006-04-24 | 2007-11-01 | Panacea Biotec Ltd. | Novel low dose pharmaceutical compositions comprising nimesulide, preparation and use thereof |
| MX2009013384A (es) * | 2007-06-08 | 2010-01-25 | Addrenex Pharmaceuticals Inc | Formulacion de liberacion extendida, y metodo para tratar disregulacion adrenergica. |
| BE1018280A3 (fr) * | 2008-09-09 | 2010-08-03 | Squarepoint Pointcarre Sprl | Composition de nimesulide a liberation prolongee. |
| US10463623B2 (en) * | 2008-09-22 | 2019-11-05 | Rubicon Research Private Limited | Compositions exhibiting delayed transit through the gastrointestinal tract |
| WO2010100657A2 (en) * | 2009-03-04 | 2010-09-10 | Fdc Limited | A novel oral controlled release dosage forms for water soluble drugs |
| WO2010138441A1 (en) * | 2009-05-28 | 2010-12-02 | Aptapharma, Inc. | Multilayer oral tablets containing a non-steroidal anti-inflammatory drug and/or acetaminophen |
| US8263581B2 (en) | 2009-07-03 | 2012-09-11 | Jdp Therapeutics, Inc. | Non-sedating antihistamine injection formulations and methods of use thereof |
| US8513259B2 (en) | 2009-07-03 | 2013-08-20 | Jdp Therapeutics, Inc. | Non-sedating antihistamine injection formulations and methods of use thereof |
| CN102188386B (zh) * | 2010-03-02 | 2013-09-04 | 海南葫芦娃制药有限公司 | 尼美舒利缓释微丸及其制备方法 |
| CN102232928A (zh) * | 2010-04-20 | 2011-11-09 | 广州艾格生物科技有限公司 | 一种尼美舒利缓释干混悬剂及其制备方法 |
| US20120010216A1 (en) * | 2010-07-06 | 2012-01-12 | Brown Arthur M | Pharmaceutical compositions containing vanoxerine |
| CN102485220A (zh) * | 2010-12-03 | 2012-06-06 | 沈阳药科大学 | 尼美舒利单层渗透泵控释片 |
| WO2012159077A2 (en) * | 2011-05-18 | 2012-11-22 | Board Of Regents, The University Of Texas System | Multiple dosing regimen oral drug delivery platform |
| CN103142565B (zh) * | 2012-04-18 | 2015-04-29 | 中国人民解放军军事医学科学院毒物药物研究所 | 一种尼美舒利的缓释药物组合物及其制备方法 |
| KR102421235B1 (ko) | 2014-02-13 | 2022-07-15 | 인사이트 코포레이션 | Lsd1 저해제로서 사이클로프로필아민 |
| CR20160395A (es) | 2014-02-13 | 2016-12-20 | Incyte Corp | Ciclopropilaminas como inhibidores de lsd1 |
| US20150275167A1 (en) * | 2014-03-28 | 2015-10-01 | Corning Incorporated | Composition and method for cell culture sustained release |
| US9695167B2 (en) | 2014-07-10 | 2017-07-04 | Incyte Corporation | Substituted triazolo[1,5-a]pyridines and triazolo[1,5-a]pyrazines as LSD1 inhibitors |
| CN105435239B (zh) * | 2014-08-29 | 2019-04-26 | 武汉光谷人福生物医药有限公司 | 美索舒利薄膜衣片及其制备方法 |
| MY191796A (en) | 2015-04-03 | 2022-07-15 | Incyte Corp | Heterocyclic compounds as lsd1 inhibitors |
| CA2987177A1 (en) * | 2015-05-25 | 2016-12-01 | Sun Pharmaceutical Industries Limited | Once-daily oral pharmaceutical composition of isotretinoin |
| CN110402244B (zh) | 2015-08-12 | 2023-02-03 | 因赛特公司 | Lsd1抑制剂的盐 |
| US9687475B1 (en) | 2016-03-24 | 2017-06-27 | Ezra Pharma Llc | Extended release pharmaceutical formulations with controlled impurity levels |
| US9675585B1 (en) | 2016-03-24 | 2017-06-13 | Ezra Pharma | Extended release pharmaceutical formulations |
| WO2018190621A1 (ko) * | 2017-04-10 | 2018-10-18 | 성균관대학교 산학협력단 | 다공성 위체류층을 포함하는 서방성 제제 및 이의 제조방법 |
| WO2020047198A1 (en) | 2018-08-31 | 2020-03-05 | Incyte Corporation | Salts of an lsd1 inhibitor and processes for preparing the same |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4424235A (en) * | 1981-09-14 | 1984-01-03 | Hoffmann-La Roche Inc. | Hydrodynamically balanced controlled release compositions containing L-dopa and a decarboxylase inhibitor |
| US4666928A (en) * | 1984-08-30 | 1987-05-19 | Merck Frosst Canada, Ind. | Propylphenoxy pyridine carboxylates as leukotriene antagonists |
| IT1215726B (it) * | 1988-01-18 | 1990-02-22 | Alfa Wassermann Spa | Formulazioni galeniche a cessione programmata. |
| IN187379B (de) * | 1996-04-12 | 2002-04-13 | Panacea Biotec Ltd | |
| JP2000510858A (ja) * | 1996-05-23 | 2000-08-22 | ノバルティス アクチエンゲゼルシャフト | ６―フルオロウルソデオキシコール酸（６―ｆｕｄｃａ）による結腸直腸癌の予防および治療 |
| IN186315B (de) * | 1996-12-12 | 2001-08-04 | Panacea Biotec Ltd | |
| ES2129010B1 (es) * | 1997-01-02 | 2000-01-16 | Gold Oscar | Composicion de accion prolongada en granulos que contienen 4-nitro-2- fenoximetansulfonanilida y su procedimiento de preparacion. |
| US5948787A (en) * | 1997-02-28 | 1999-09-07 | Alza Corporation | Compositions containing opiate analgesics |
| AU9062998A (en) * | 1997-09-11 | 1999-03-29 | Nycomed Danmark A/S | Modified release multiple-units compositions of non-steroid anti-inflammatory drug substances (nsaids) |
| IN188720B (de) * | 1997-11-06 | 2002-11-02 | Panacea Biotec Ltd | |
| FR2772615B1 (fr) * | 1997-12-23 | 2002-06-14 | Lipha | Comprime multicouche pour la liberation instantanee puis prolongee de substances actives |
| US6184220B1 (en) * | 1998-03-27 | 2001-02-06 | Boehringer Ingelheim Pharma Kg | Oral suspension of pharmaceutical substance |
| BR9804993A (pt) * | 1998-11-10 | 2000-06-06 | Panacea Biotec Ltd | Composição antialérgica e antiinflamatória |
-
2000
- 2000-09-27 CN CN200910159790A patent/CN101804041A/zh active Pending
- 2000-09-27 KR KR1020027003996A patent/KR100621281B1/ko not_active IP Right Cessation
- 2000-09-27 DE DE60043447T patent/DE60043447D1/de not_active Expired - Lifetime
- 2000-09-27 MX MXPA02003321A patent/MXPA02003321A/es active IP Right Grant
- 2000-09-27 EP EP00992052A patent/EP1218889B1/de not_active Expired - Lifetime
- 2000-09-27 PT PT00992052T patent/PT1218889E/pt unknown
- 2000-09-27 WO PCT/IN2000/000094 patent/WO2001022791A2/en not_active Application Discontinuation
- 2000-09-27 CN CN00814424A patent/CN1399543A/zh active Pending
- 2000-09-27 CA CA002385890A patent/CA2385890C/en not_active Expired - Fee Related
- 2000-09-27 CZ CZ20021076A patent/CZ20021076A3/cs unknown
- 2000-09-27 ES ES00992052T patent/ES2337547T3/es not_active Expired - Lifetime
- 2000-09-27 AT AT00992052T patent/ATE450865T1/de active
- 2000-09-27 AP APAP/P/2002/002450A patent/AP1954A/en active
- 2000-09-27 IL IL14886400A patent/IL148864A0/xx active IP Right Grant
- 2000-09-27 UA UA2002032356A patent/UA80667C2/uk unknown
- 2000-09-27 RU RU2002111365/15A patent/RU2238087C2/ru not_active IP Right Cessation
- 2000-09-27 AU AU28799/01A patent/AU774099B2/en not_active Ceased
- 2000-09-27 NZ NZ518052A patent/NZ518052A/en not_active IP Right Cessation
- 2000-09-27 DK DK00992052.1T patent/DK1218889T3/da active
- 2000-09-27 HU HU0204451A patent/HUP0204451A3/hu unknown
- 2000-09-27 RS YUP-234/02A patent/RS50303B/sr unknown
- 2000-09-27 JP JP2001526021A patent/JP4359412B2/ja not_active Expired - Fee Related
- 2000-09-27 BR BR0014383-9A patent/BR0014383A/pt not_active IP Right Cessation
-
2002
- 2002-03-25 IL IL148864A patent/IL148864A/en unknown
- 2002-03-26 ZA ZA200202411A patent/ZA200202411B/en unknown
- 2002-03-27 NO NO20021540A patent/NO20021540L/no not_active Application Discontinuation
- 2002-04-11 BG BG106605A patent/BG66093B1/bg unknown
-
2006
- 2006-10-10 US US11/545,718 patent/US20070128276A1/en not_active Abandoned
-
2007
- 2007-06-01 JP JP2007147523A patent/JP2007217436A/ja active Pending
- 2007-10-26 US US11/978,162 patent/US20080160082A1/en not_active Abandoned
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