ZA200109595B - 13-methyl-erythromycin derivatives. - Google Patents

13-methyl-erythromycin derivatives.

Info

Publication number
ZA200109595B
ZA200109595B ZA200109595A ZA200109595A ZA200109595B ZA 200109595 B ZA200109595 B ZA 200109595B ZA 200109595 A ZA200109595 A ZA 200109595A ZA 200109595 A ZA200109595 A ZA 200109595A ZA 200109595 B ZA200109595 B ZA 200109595B
Authority
ZA
South Africa
Prior art keywords
methyl
erythromycin derivatives
erythromycin
derivatives
Prior art date
Application number
ZA200109595A
Other languages
English (en)
Inventor
Dirlam John Philip
Takushi Keneko
Mcarthur Hamish Alastai Irvine
Wei-Guo Su
Yong-Jin Wu
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of ZA200109595B publication Critical patent/ZA200109595B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
ZA200109595A 1999-05-24 2001-11-21 13-methyl-erythromycin derivatives. ZA200109595B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US13546899P 1999-05-24 1999-05-24

Publications (1)

Publication Number Publication Date
ZA200109595B true ZA200109595B (en) 2003-05-28

Family

ID=22468240

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200109595A ZA200109595B (en) 1999-05-24 2001-11-21 13-methyl-erythromycin derivatives.

Country Status (32)

Country Link
US (2) US20030100518A1 (xx)
EP (1) EP1180110A1 (xx)
JP (1) JP2003500414A (xx)
KR (1) KR20020016799A (xx)
CN (1) CN1351608A (xx)
AP (1) AP2001002302A0 (xx)
AR (1) AR020032A1 (xx)
AU (1) AU3832100A (xx)
BG (1) BG106127A (xx)
BR (1) BR0010938A (xx)
CA (1) CA2373117C (xx)
CZ (1) CZ20013733A3 (xx)
DZ (1) DZ3045A1 (xx)
EA (1) EA200100983A1 (xx)
EE (1) EE200100613A (xx)
HK (1) HK1045523A1 (xx)
HR (1) HRP20010866A2 (xx)
HU (1) HUP0201516A3 (xx)
IL (1) IL145739A0 (xx)
IS (1) IS6128A (xx)
MA (1) MA26740A1 (xx)
NO (1) NO20015172L (xx)
OA (1) OA11945A (xx)
PA (1) PA8495101A1 (xx)
PE (1) PE20010171A1 (xx)
PL (1) PL352720A1 (xx)
SK (1) SK15162001A3 (xx)
TN (1) TNSN00108A1 (xx)
TR (1) TR200103395T2 (xx)
UY (1) UY26161A1 (xx)
WO (1) WO2000071557A1 (xx)
ZA (1) ZA200109595B (xx)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AP9801420A0 (en) 1998-01-02 1998-12-31 Pfizer Prod Inc Novel macrolides.
AP1060A (en) 1998-01-02 2002-04-23 Pfizer Prod Inc Novel erythromycin derivatives.
ID28286A (id) 1998-11-03 2001-05-10 Pfizer Prod Inc Antibiotik-antibiotik makrolida baru
KR20020002380A (ko) 1999-01-27 2002-01-09 실버스타인 아써 에이. 케톨라이드 항생물질
US6590083B1 (en) 1999-04-16 2003-07-08 Ortho-Mcneil Pharmaceutical, Inc. Ketolide antibacterials
JP2002542197A (ja) 1999-04-16 2002-12-10 オーソ−マクニール・フアーマシユーチカル・インコーポレーテツド ケトライド抗菌剤
US6939861B2 (en) 1999-04-16 2005-09-06 Kosan Biosciences, Inc. Amido macrolides
US6451768B1 (en) 1999-04-16 2002-09-17 Kosan Biosciences, Inc. Macrolide antiinfective agents
US6514944B2 (en) 1999-04-16 2003-02-04 Kosan Biosciences, Inc. Macrolide antiinfective agents
AU773678B2 (en) 1999-04-16 2004-06-03 Kosan Biosciences, Inc. Macrolide antiinfective agents
AP2001002302A0 (en) 1999-05-24 2001-10-25 Pfizer Prod Inc 13-Methyl erythromycin derivatives.
DK1167376T3 (da) 2000-06-30 2004-10-25 Pfizer Prod Inc Makrolidantibiotika
GB0127349D0 (en) 2001-11-14 2002-01-02 Glaxo Group Ltd Macrolides
CA2469304A1 (en) 2001-12-05 2003-06-19 Ortho-Mcneil Pharmaceutical, Inc. 6-o acyl ketolide antibacterials
WO2003090761A1 (en) * 2002-04-25 2003-11-06 Abbott Laboratories 9-oxime macrolide antibacterials
EP1579864A1 (en) * 2002-04-25 2005-09-28 Abbott Laboratories Oxolide antibacterials
GB0225384D0 (en) 2002-10-31 2002-12-11 Glaxo Group Ltd Novel compounds
US7414030B2 (en) * 2004-01-07 2008-08-19 Enanta Pharmaceuticals, Inc. 6-11 Bicyclic erythromycin derivatives
EP1836211B1 (en) 2004-12-21 2010-03-03 Pfizer Products Inc. Macrolides
CN101568343A (zh) 2006-06-12 2009-10-28 雷蒙特亚特特拉维夫大学有限公司 用于治疗癌症的方法
CN101175322B (zh) * 2007-11-16 2010-12-15 华为技术有限公司 一种小区选择的方法
KR101043637B1 (ko) * 2009-07-13 2011-06-24 태석정공 주식회사 휴대용 듀얼 모니터의 카메라 모듈 결합구조
AR085286A1 (es) 2011-02-21 2013-09-18 Taisho Pharmaceutical Co Ltd Derivado de macrolido sustituido en la posicion c-4
US10987370B2 (en) 2012-12-24 2021-04-27 Ramot At Tel-Aviv University Ltd. Methods of inducing read-through of a nonsense mutation associated with ataxia telangiectasia, Rett syndrome or spinal muscular atrophy by erythromycin or azithromycin
WO2014165792A2 (en) 2013-04-04 2014-10-09 President And Fellows Of Harvard College Macrolides and methods of their preparation and use
CA2963815A1 (en) * 2014-10-08 2016-04-14 President And Fellows Of Harvard College 14-membered ketolides and methods of their preparation and use
US10640528B2 (en) 2015-03-25 2020-05-05 President And Fellows Of Havard College Macrolides with modified desosamine sugars and uses thereof

Family Cites Families (102)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US77302A (en) * 1868-04-28 mat son
US61858A (en) * 1867-02-05 Improved washing machine
US52328A (en) * 1866-01-30 Improved mode of attaching car-wheels to axles
US100518A (en) * 1870-03-08 Roland s
US25937A (en) * 1859-11-01 ballou
US40007A (en) * 1863-09-22 Improvement in railroad-car brakes
US111317A (en) * 1871-01-31 Improvement in culinary vessels
US13662A (en) * 1855-10-09 Improvement in sewing-machines
US100742A (en) * 1870-03-15 Improvement in lawn-mowers
US13665A (en) * 1855-10-09 Daguerreotype-plate holder
US156027A (en) * 1874-10-20 Improvement in loom-shuttles
US61857A (en) * 1867-02-05 Improvement in top-drivers or spinners
US61856A (en) * 1867-02-05 Enos s
US13281A (en) * 1855-07-17 Churn
US50254A (en) * 1865-10-03 Improvement in portable scales
US3923784A (en) * 1973-09-10 1975-12-02 Hoffmann La Roche Erythromycin a derivatives
YU43116B (en) * 1979-04-02 1989-04-30 Pliva Pharm & Chem Works Process for preparing 11-aza-4-o-cladinosyl-6-o-desosaminyl-15-ethyl-7,13,14-trihydroxy-3,5,7,9,12,14-hexamethyl-oxacyclopentadecane-2-one(11-aza-10-deox
US4331803A (en) * 1980-06-04 1982-05-25 Taisho Pharmaceutical Co., Ltd. Novel erythromycin compounds
YU43006B (en) * 1981-03-06 1989-02-28 Pliva Pharm & Chem Works Process for preparing n-methyl-11-aza-10-deoxo-10-dihydro erythromycin and derivatives thereof
US4474768A (en) * 1982-07-19 1984-10-02 Pfizer Inc. N-Methyl 11-aza-10-deoxo-10-dihydro-erytromycin A, intermediates therefor
JPS61103890A (ja) * 1984-10-26 1986-05-22 Taisho Pharmaceut Co Ltd ６−０−メチルエリスロマイシンａ誘導体
JPS61229895A (ja) * 1985-04-03 1986-10-14 Nippon Zeon Co Ltd 保護化デス−ｎ−メチルエリスロマイシン誘導体
GB8521402D0 (en) * 1985-08-28 1985-10-02 Beecham Group Plc Chemical compounds
US4672056A (en) * 1985-11-12 1987-06-09 Abbott Laboratories Erythromycin A derivatives and method of use
EP0283055B1 (en) * 1987-09-03 1990-08-29 SOUR PLIVA farmaceutska, Kemijska prehrambena i kozmeticka industrija, n.sol.o. 10-dihydro-10-deoxo-11-azaerythronolide-a-compounds, methods and intermediates for the manufacture thereof and their use in pharmaceuticals and in the manufacture thereof
US5141926A (en) * 1990-04-18 1992-08-25 Abbott Laboratories Erythromycin derivatives
IL114589A (en) * 1990-11-21 1999-12-22 Roussel Uclaf Intermediates for the preparation of the history of erythromycin
US5824513A (en) * 1991-01-17 1998-10-20 Abbott Laboratories Recombinant DNA method for producing erythromycin analogs
US6060234A (en) 1991-01-17 2000-05-09 Abbott Laboratories Polyketide derivatives and recombinant methods for making same
US5985844A (en) * 1992-03-26 1999-11-16 Merck & Co., Inc. Homoerythromycin A derivatives modified at the 4"-and 8A-positions
CA2064634C (en) 1991-04-04 1998-08-04 James V. Heck 9-deoxo-8a-aza-8a-homoerythromycin a derivatives modified at the 4"- and8a-positions
US5523399A (en) * 1991-12-27 1996-06-04 Taisho Pharmaceutical Co., Ltd. 5-O-desosaminylerythronolide derivatives
FR2691464B1 (fr) 1992-05-21 1995-06-02 Roussel Uclaf Nouveaux dérivés de la 1-oxa 6-azacyclopentadécane 13,15-dione, leur procédé de préparation et leur application comme médicaments.
US5414926A (en) * 1992-10-09 1995-05-16 Sumitomo Wiring Systems, Ltd. Terminal crimping apparatus
FR2697524B1 (fr) * 1992-11-05 1994-12-23 Roussel Uclaf Nouveaux dérivés de l'érythromycine, leur procédé de préparation et leur application comme médicaments.
US5527780A (en) * 1992-11-05 1996-06-18 Roussel Uclaf Erythromycin derivatives
US5332807A (en) 1993-04-14 1994-07-26 Merck & Co., Inc. Process of producing 8A- and 9A-azalide antibiotics
FR2702480B1 (fr) * 1993-03-09 1995-04-28 Roussel Uclaf Nouveaux dérivés de l'érythromycine, leur procédé de préparation et leur application comme médicaments.
HRP931480B1 (en) * 1993-12-08 1997-08-31 Sour Pliva 9a-N-(N'-CARBAMONYL) and 9a-N-(N'-THIOCARBAMONYL) DERIVATES OF 9-DEOXO-9a-HOMOERYTHROMYCIN A
US5441939A (en) * 1994-03-04 1995-08-15 Pfizer Inc. 3"-desmethoxy derivatives of erythromycin and azithromycin
FR2718450B1 (fr) * 1994-04-08 1997-01-10 Roussel Uclaf Nouveaux dérivés de l'érythromycine, leur procédé de préparation et leur application comme médicaments.
FR2719587B1 (fr) * 1994-05-03 1996-07-12 Roussel Uclaf Nouveaux dérivés de l'érythromycine, leur procédé de préparation et leur application comme médicaments.
FR2727969B1 (fr) 1994-12-09 1997-01-17 Roussel Uclaf Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
FR2732023B1 (fr) 1995-03-22 1997-04-30 Roussel Uclaf Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
FR2732684B1 (fr) 1995-04-06 1997-04-30 Roussel Uclaf Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
US5747466A (en) * 1995-11-08 1998-05-05 Abbott Laboratories 3-deoxy-3-descladinose derivatives of erythromycins A and B
US6274715B1 (en) * 1995-11-08 2001-08-14 Abbott Laboratories Tricyclic erythromycin derivatives
FR2742757B1 (fr) * 1995-12-22 1998-01-30 Roussel Uclaf Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
FR2745290B1 (fr) * 1996-02-28 1998-04-03 Roussel Uclaf Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
US6077943A (en) * 1996-03-01 2000-06-20 Takeda Chemical Industries, Ltd. Method of producing erythromycin derivative
US5719272A (en) 1996-04-02 1998-02-17 Abbott Laboratories 2'-protected 3'-dimethylamine, 9-etheroxime erythromycin A derivatives
US5750510A (en) * 1997-04-04 1998-05-12 Abbott Laboratories 3-descladinose-2,3-anhydroerythromycin derivatives
WO1997042204A1 (en) * 1996-05-07 1997-11-13 Abbott Laboratories 6-o-substituted erythromycins and method for making them
NZ332320A (en) * 1996-05-07 2000-07-28 Abbott Lab 6-0-substituted erythromycin compounds and medicaments
FR2748746B1 (fr) * 1996-05-14 1998-08-14 Hoechst Marion Roussel Inc Nouveau procede d'isomerisation du radical methyle en 10 de derives de l'erythromycine
DE19626036A1 (de) 1996-06-28 1998-01-02 Whitaker Corp Optischer Steckverbinder
AP1029A (en) 1996-07-05 2001-12-11 Biotica Tech Limited Erythromycins and process for their preparation.
US6271255B1 (en) * 1996-07-05 2001-08-07 Biotica Technology Limited Erythromycins and process for their preparation
FR2751656B1 (fr) * 1996-07-24 1998-10-16 Hoechst Marion Roussel Inc Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
UA51730C2 (uk) * 1996-09-04 2002-12-16 Ебботт Лабораторіз 6-o-заміщені кетоліди з антибактеріальною активністю, спосіб їх одержання (варіанти), фармацевтична композиція та спосіб регулювання бактеріальної інфекції у ссавців
US5804565A (en) 1996-09-24 1998-09-08 Taisho Pharmaceutical Co., Ltd. Erythromycin A derivatives
FR2754821B1 (fr) 1996-10-23 2003-04-04 Hoechst Marion Roussel Inc Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
JP4077882B2 (ja) 1996-11-27 2008-04-23 大正製薬株式会社 エリスロマイシンａ誘導体
FR2757168B1 (fr) 1996-12-12 1999-06-11 Hoechst Marion Roussel Inc Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
FR2760017B1 (fr) 1997-02-27 1999-04-30 Hoechst Marion Roussel Inc Nouveaux derives de l'erytromycine, leur procede de preparation et leur application comme medicaments
WO1998040392A1 (fr) * 1997-03-10 1998-09-17 Taisho Pharmaceutical Co., Ltd. Derives d'erythromycine a
WO1998051696A1 (en) 1997-05-09 1998-11-19 Pfizer Products Inc. Erythromycin derivatives
US6407074B1 (en) * 1997-06-11 2002-06-18 Pfizer Inc C-4″-substituted macrolide derivatives
ID24529A (id) 1997-06-11 2000-07-20 Pfizer Prod Inc Turunan-turunan 9-oksima eritromisin
HN1998000086A (es) 1997-06-11 1999-03-08 Pfizer Prod Inc Derivados de 9 - desofo - 9 aza - 9a - homoeritromicina a - c - 4 sustituidos.
US20020025937A1 (en) 2000-03-20 2002-02-28 Yong-Jin Wu 9-oxime erythromycin derivatives
EP0895999A1 (en) * 1997-08-06 1999-02-10 Pfizer Products Inc. C-4" substituted macrolide antibiotics
US5868549A (en) * 1997-08-29 1999-02-09 Hk Systems, Inc. Palletizer with air assisted slide plate assembly and indexing pallet hoist
PA8461401A1 (es) * 1997-10-29 2000-05-24 Pfizer Prod Inc Derivados de eritromicina triciclicos
HN1998000159A (es) * 1997-10-29 1999-02-09 Monsanto Co Derivados de 9- amino - 3 ceto eritromicina
EP1044985A4 (en) 1997-12-11 2001-04-18 Hokuriku Pharmaceutical ERYTHROMYCIN DERIVATIVES
AP1060A (en) * 1998-01-02 2002-04-23 Pfizer Prod Inc Novel erythromycin derivatives.
AP9801420A0 (en) 1998-01-02 1998-12-31 Pfizer Prod Inc Novel macrolides.
EP0941998B1 (en) * 1998-03-03 2004-09-01 Pfizer Products Inc. 3,6-ketal macrolide antibiotics
FR2777282B1 (fr) * 1998-04-08 2001-04-20 Hoechst Marion Roussel Inc Nouveaux derives de la 2-fluoro 3-de((2,6-dideoxy 3-c-methyl 3-0-methyl-alpha-l-ribohexopyranosyl) oxyl) 6-o-methyl 3-oxo erythromycine, leur procede de preparation et leur application a la synthese de principes actifs de medicaments
WO1999062920A1 (en) 1998-06-03 1999-12-09 Pfizer Products Inc. Tricyclic 3-keto derivatives of 6-o-methylerythromycin
US6043227A (en) * 1998-08-19 2000-03-28 Pfizer Inc. C11 carbamates of macrolide antibacterials
EP1115732B1 (en) * 1998-09-22 2005-06-29 Pfizer Products Inc. Carbamate and carbazate ketolide antibiotics
US6100240A (en) * 1998-10-09 2000-08-08 Pfizer Inc Macrolide derivatives
FR2785612A1 (fr) 1998-11-10 2000-05-12 Hoechst Marion Roussel Inc Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
ID28286A (id) 1998-11-03 2001-05-10 Pfizer Prod Inc Antibiotik-antibiotik makrolida baru
UA70972C2 (uk) * 1998-11-20 2004-11-15 Пфайзер Продактс Інк. 13-членні азаліди і їх застосування як антибіотиків
FR2786188B1 (fr) 1998-11-24 2002-10-31 Hoechst Marion Roussel Inc Nouveaux derives de l'erythromycine, leur procede de preparation et leur applicaion comme medicaments
KR20020002380A (ko) 1999-01-27 2002-01-09 실버스타인 아써 에이. 케톨라이드 항생물질
FR2789392B1 (fr) * 1999-02-04 2001-10-05 Hoechst Marion Roussel Inc Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
JP2002542197A (ja) 1999-04-16 2002-12-10 オーソ−マクニール・フアーマシユーチカル・インコーポレーテツド ケトライド抗菌剤
US20020061857A1 (en) 1999-04-23 2002-05-23 Yong-Jin Wu 9-amino-3-oxo erythromycin derivatives
US20020077302A1 (en) 1999-04-23 2002-06-20 Yong-Jin Wu Tricyclic erythromycin derivatives
US6355620B1 (en) * 1999-05-14 2002-03-12 Abbott Laboratories C-2 modified erythromycin derivatives
AP2001002302A0 (en) 1999-05-24 2001-10-25 Pfizer Prod Inc 13-Methyl erythromycin derivatives.
EP1114826A3 (en) 1999-12-29 2001-10-31 Pfizer Products Inc. Novel antibacterial and prokinetic macrolides
EP1122261A3 (en) 2000-01-31 2001-09-26 Pfizer Products Inc. 13 and 14-membered antibacterial macrolides
EP1146051A3 (en) 2000-04-10 2001-10-31 Pfizer Products Inc. Erythromycin A derivatives
US20020061856A1 (en) 2000-04-24 2002-05-23 Yong-Jin Wu Novel tricyclic erythromycin derivatives
DK1167376T3 (da) 2000-06-30 2004-10-25 Pfizer Prod Inc Makrolidantibiotika
US20020115621A1 (en) 2000-08-07 2002-08-22 Wei-Gu Su Macrolide antibiotics
US20020111317A1 (en) 2000-09-25 2002-08-15 Leonard Katz Sixteen-membered macrolide compounds

Also Published As

Publication number Publication date
CA2373117A1 (en) 2000-11-30
KR20020016799A (ko) 2002-03-06
SK15162001A3 (sk) 2003-02-04
AU3832100A (en) 2000-12-12
BR0010938A (pt) 2002-03-19
NO20015172L (no) 2002-01-23
JP2003500414A (ja) 2003-01-07
IL145739A0 (en) 2002-07-25
AR020032A1 (es) 2002-03-27
CA2373117C (en) 2006-02-28
CN1351608A (zh) 2002-05-29
HRP20010866A2 (en) 2003-06-30
BG106127A (bg) 2002-05-31
MA26740A1 (fr) 2004-12-20
EE200100613A (et) 2003-02-17
US20030229031A1 (en) 2003-12-11
CZ20013733A3 (cs) 2002-11-13
HUP0201516A2 (en) 2002-08-28
AP2001002302A0 (en) 2001-10-25
HUP0201516A3 (en) 2003-03-28
EP1180110A1 (en) 2002-02-20
EA200100983A1 (ru) 2002-10-31
US6777543B2 (en) 2004-08-17
PL352720A1 (en) 2003-09-08
US20030100518A1 (en) 2003-05-29
WO2000071557A1 (en) 2000-11-30
PA8495101A1 (es) 2002-08-26
OA11945A (en) 2006-04-13
UY26161A1 (es) 2000-12-29
HK1045523A1 (zh) 2002-11-29
IS6128A (is) 2001-10-26
DZ3045A1 (fr) 2004-03-27
PE20010171A1 (es) 2001-02-10
TR200103395T2 (tr) 2002-04-22
NO20015172D0 (no) 2001-10-23
TNSN00108A1 (fr) 2002-05-30

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