YU47594B - KRISTALNA SO (4-DI-N-PROPIL)AMINO-6-AMINOKARBONIL-1,3,4,5-TETRAHIDROBENZ/cd/INDOLA I POSTUPAK ZA NJENO DOBIJANJE - Google Patents

KRISTALNA SO (4-DI-N-PROPIL)AMINO-6-AMINOKARBONIL-1,3,4,5-TETRAHIDROBENZ/cd/INDOLA I POSTUPAK ZA NJENO DOBIJANJE

Info

Publication number
YU47594B
YU47594B YU32791A YU32791A YU47594B YU 47594 B YU47594 B YU 47594B YU 32791 A YU32791 A YU 32791A YU 32791 A YU32791 A YU 32791A YU 47594 B YU47594 B YU 47594B
Authority
YU
Yugoslavia
Prior art keywords
indola
aminocarbonyl
propyl
amino
obtaining
Prior art date
Application number
YU32791A
Other languages
English (en)
Serbo-Croatian (sh)
Other versions
YU32791A (sh
Inventor
T.J. Kress
D.L. Varie
Original Assignee
Eli Lilly And Company
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly And Company filed Critical Eli Lilly And Company
Publication of YU32791A publication Critical patent/YU32791A/sh
Publication of YU47594B publication Critical patent/YU47594B/sh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56—Ring systems containing three or more rings
    • C07D209/80—[b, c]- or [b, d]-condensed
    • C07D209/90—Benzo [c, d] indoles; Hydrogenated benzo [c, d] indoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/32—Alcohol-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Addiction (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Anesthesiology (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Child & Adolescent Psychology (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
YU32791A 1990-02-26 1991-02-25 KRISTALNA SO (4-DI-N-PROPIL)AMINO-6-AMINOKARBONIL-1,3,4,5-TETRAHIDROBENZ/cd/INDOLA I POSTUPAK ZA NJENO DOBIJANJE YU47594B (sh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US48518590A 1990-02-26 1990-02-26

Publications (2)

Publication Number Publication Date
YU32791A YU32791A (sh) 1994-01-20
YU47594B true YU47594B (sh) 1995-10-24

Family

ID=23927224

Family Applications (1)

Application Number Title Priority Date Filing Date
YU32791A YU47594B (sh) 1990-02-26 1991-02-25 KRISTALNA SO (4-DI-N-PROPIL)AMINO-6-AMINOKARBONIL-1,3,4,5-TETRAHIDROBENZ/cd/INDOLA I POSTUPAK ZA NJENO DOBIJANJE

Country Status (28)

Country Link
US (1) US5397799A (index.php)
EP (1) EP0444852B1 (index.php)
JP (1) JP3157007B2 (index.php)
KR (1) KR100208114B1 (index.php)
CN (1) CN1027503C (index.php)
AT (1) ATE126506T1 (index.php)
AU (1) AU629453B2 (index.php)
BR (1) BR9100767A (index.php)
CA (1) CA2037099C (index.php)
CY (1) CY1887A (index.php)
DE (1) DE69112099T2 (index.php)
DK (1) DK0444852T3 (index.php)
ES (1) ES2077796T3 (index.php)
FI (1) FI95464C (index.php)
GR (1) GR3017940T3 (index.php)
HK (1) HK175495A (index.php)
HU (1) HU217118B (index.php)
IE (1) IE67801B1 (index.php)
IL (1) IL97306A (index.php)
LV (1) LV10251B (index.php)
NO (1) NO174149C (index.php)
NZ (1) NZ237181A (index.php)
PT (1) PT96852B (index.php)
RU (2) RU2034837C1 (index.php)
SG (1) SG69975A1 (index.php)
TW (1) TW219933B (index.php)
YU (1) YU47594B (index.php)
ZA (1) ZA911258B (index.php)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5302612A (en) * 1990-02-26 1994-04-12 Eli Lilly And Company 6-substituted-hexahydrobenz[cd]indoles
IL97309A (en) * 1990-02-26 1996-11-14 Lilly Co Eli Intermediates for hexahydrobenz Úcd¾ indoles and process for the preparation of pure enantiomers thereof
IL97308A (en) * 1990-02-26 1996-10-31 Lilly Co Eli 6-Substituted-hexahydrobenz (cd) indoles process for their preparation and pharmaceutical compositions containing them
US5633273A (en) * 1991-03-28 1997-05-27 Eli Lilly And Company 6-heterocyclic-4-amino-1,2,2a,3,4,5-hexahydrobenz[cd] indoles
US5364856A (en) * 1991-03-28 1994-11-15 Eli Lilly And Company 6-heterocyclic-4-amino-1,3,4,5-tetrahydrobenz[CD]indoles
TW248556B (index.php) * 1993-01-18 1995-06-01 Takeda Pharm Industry Co
UA53205C2 (en) * 2002-04-03 2006-06-15 Pharmatech Close Joint Stock C Antidepressant formulation and method for its manufacture
US7588924B2 (en) 2006-03-07 2009-09-15 Procter & Gamble Company Crystal of hypoxia inducible factor 1 alpha prolyl hydroxylase
SI3357911T1 (sl) * 2006-06-26 2022-10-28 Akebia Therapeutics Inc. Inhibitorji prolil hidroksilaze in postopki uporabe
KR20120088833A (ko) 2009-11-06 2012-08-08 에르피오 세러퓨틱스 인코포레이티드 저산소증 유발 인자-1 알파의 안정화 증가 방법
AU2012268400C1 (en) 2011-06-06 2016-12-22 Akebia Therapeutics Inc. Compounds and compositions for stabilizing hypoxia inducible factor-2 alpha as a method for treating cancer
NO2686520T3 (index.php) 2011-06-06 2018-03-17
CN114404414A (zh) 2013-06-13 2022-04-29 阿克比治疗有限公司 用于治疗贫血症的组合物和方法
MX2021001169A (es) 2013-11-15 2023-02-10 Akebia Therapeutics Inc Formas sólidas de ácido {[5-(3-clorofenil)-3-hidroxipiridin-2-carb onil]amino}acético, composiciones, y usos de las mismas.
EP3247355A4 (en) 2015-01-23 2018-06-13 Akebia Therapeutics, Inc. Solid forms of 2-(5-(3-fluorophenyl)-3-hydroxypicolinamido)acetic acid, compositions, and uses thereof
KR102866021B1 (ko) 2015-04-01 2025-09-30 아케비아 테라퓨틱스 인코포레이티드 빈혈 치료용 조성물 및 방법
WO2019217550A1 (en) 2018-05-09 2019-11-14 Akebia Therapeutics, Inc. Process for preparing 2-[[5-(3-chlorophenyl)-3-hydroxypyridine-2-carbonyl]amino]acetic acid
US11524939B2 (en) 2019-11-13 2022-12-13 Akebia Therapeutics, Inc. Solid forms of {[5-(3-chlorophenyl)-3-hydroxypyridine-2-carbonyl]amino} acetic acid

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4110339A (en) * 1977-11-25 1978-08-29 Eli Lilly And Company 4-(Di-n-propyl)amino-1,3,4,5-tetrahydrobenz[cd]indole
US4576959A (en) * 1984-02-06 1986-03-18 Eli Lilly And Company 6-Substituted-4-dialkylaminotetrahydrobenz[c,d]indoles
US4745126A (en) * 1987-03-12 1988-05-17 Eli Lilly And Company Method of treating anxiety with tetrahydrobenz[c,d]indole-6-carboxamides
DE3809155A1 (de) * 1988-03-18 1989-09-28 Bayer Ag 1,3,4,5-tetrahydrobenz-(c,d)-indole
US5204340A (en) * 1989-04-11 1993-04-20 Eli Lilly And Company Tetrahydrobenz(c,d)indole serotonin agonists
US5229409A (en) * 1990-08-15 1993-07-20 Eli Lilly And Company 6-substituted-tetrahydrobenz[cd]indoles

Also Published As

Publication number Publication date
US5397799A (en) 1995-03-14
EP0444852A3 (en) 1992-02-19
IL97306A (en) 1996-10-16
DE69112099D1 (de) 1995-09-21
NO174149B (no) 1993-12-13
ZA911258B (en) 1992-10-28
NO174149C (no) 1994-03-23
FI95464C (fi) 1996-02-12
EP0444852A2 (en) 1991-09-04
HUT56542A (en) 1991-09-30
CN1054589A (zh) 1991-09-18
DE69112099T2 (de) 1996-02-08
HK175495A (en) 1995-11-24
IL97306A0 (en) 1992-05-25
FI95464B (fi) 1995-10-31
PT96852A (pt) 1991-10-31
HU217118B (hu) 1999-11-29
AU629453B2 (en) 1992-10-01
IE67801B1 (en) 1996-05-01
CA2037099A1 (en) 1991-08-27
YU32791A (sh) 1994-01-20
RU2034837C1 (ru) 1995-05-10
NZ237181A (en) 1992-06-25
IE910625A1 (en) 1991-08-28
NO910735D0 (no) 1991-02-25
RU2083561C1 (ru) 1997-07-10
KR100208114B1 (ko) 1999-07-15
JPH04217662A (ja) 1992-08-07
TW219933B (index.php) 1994-02-01
BR9100767A (pt) 1991-10-29
ATE126506T1 (de) 1995-09-15
JP3157007B2 (ja) 2001-04-16
NO910735L (no) 1991-08-27
GR3017940T3 (en) 1996-02-29
LV10251B (en) 1995-04-20
CA2037099C (en) 2001-09-11
SG69975A1 (en) 2000-01-25
KR910021375A (ko) 1991-12-20
FI910895L (fi) 1991-08-27
CY1887A (en) 1996-04-05
AU7197191A (en) 1991-08-29
EP0444852B1 (en) 1995-08-16
LV10251A (lv) 1994-10-20
ES2077796T3 (es) 1995-12-01
CN1027503C (zh) 1995-01-25
DK0444852T3 (da) 1995-12-11
PT96852B (pt) 1998-07-31
FI910895A0 (fi) 1991-02-25

Similar Documents

Publication Publication Date Title
YU47594B (sh) KRISTALNA SO (4-DI-N-PROPIL)AMINO-6-AMINOKARBONIL-1,3,4,5-TETRAHIDROBENZ/cd/INDOLA I POSTUPAK ZA NJENO DOBIJANJE
FI954944A7 (fi) Indolijohdannaisia 5-HT1-kaltaisina agonisteina käytettäväksi migreenin hoitoon
RU94036004A (ru) Промежуточные соединения для получения ароматических аминоспиртовых производных
ATE114151T1 (de) Benzocyclobutyl- oder indanyl-alkyl-amino-alkyl substituierte 3-benzazepin-2-ones, verwendbar in der behandlung von kardiovaskularen krankheiten.
MY131298A (en) 5-heteroyl indole derivatives
ES2175087T3 (es) Compuestos triciclicos utiles en el tratamiento de trastornos de proliferacion celular.
NO905608L (no) Fremgangsmaate for fremstilling av a-nor-steroid-3-karboksylsyrederivater.
DE69528273D1 (de) 1,2-substituierte imidazolylverbindungen zur behandlung von entzündungen
NO924433D0 (no) Isoksazol-4-karboksylsyreamider og hydroksyalkyliden-cyaneddiksyreamider, legemidler inneholdende disse forbindelsene og deres anvendelse
NO914092D0 (no) Fremgangsmaate for fremstilling av mercaptoacetylamidderivater
ATE187965T1 (de) Substituierte pyrazolyl-benzolsulfonamide zur behandlung von entzündungen
RU95114376A (ru) Нитроэфиры, обладающие фармакологической активностью, и способ их получения
NO301542B1 (no) Nye pyrazin-derivater
DK0533824T3 (da) Piperidylsubstituerede indoler
AU3582095A (en) Isothiourea derivatives as no synthase inhibitors
ATE222492T1 (de) Verwendung von indolderivaten als 5ht1-agonisten
ATE81976T1 (de) 2-pyrimidinyl-1-piperazin-derivate zur behandlung von alkoholismus.
YU140391A (sh) 6-supstituisani-heksahidrobenz (cd)-indoli
NO175098C (no) Analogifremgangsmåte for fremstilling av substituerte indoler
BG37839A3 (bg) Метод за получаване на производни на ортокондензиран пирол
DK23392D0 (da) Heterocykliske forbindelser, deres anvendelse og fremstilling
MX10256A (es) Procedimiento para preparar nuevas 3-fenil-7h-tiazolo(3, 2-b) (1, 2, 4) triazin-7-onas.
EA199900710A1 (ru) Кристаллическая гидратированная натриевая соль (е)-4,6-дихлор-3-(2-оксо-1-фенилпирролидин-3-илиденметил)-1н-индол-2-карбоновой кислоты
ES8601997A1 (es) Un procedimiento para preparar derivados de pirrolo (3,2,1-hi)indol
YU46150B (sh) Racemski i optički aktivni derivati 14-hidrpksi-imino-eburnana kao i postupak za njihovo dobijanje