YU47207B - Postupak za dobijanje estarskih derivata ftalazinsirćetne kiseline i odgovarajućeg intermedijara - Google Patents

Postupak za dobijanje estarskih derivata ftalazinsirćetne kiseline i odgovarajućeg intermedijara

Info

Publication number
YU47207B
YU47207B YU42489A YU42489A YU47207B YU 47207 B YU47207 B YU 47207B YU 42489 A YU42489 A YU 42489A YU 42489 A YU42489 A YU 42489A YU 47207 B YU47207 B YU 47207B
Authority
YU
Yugoslavia
Prior art keywords
acid
formula
solvent
phthalasin
procedure
Prior art date
Application number
YU42489A
Other languages
English (en)
Other versions
YU42489A (en
Inventor
T. Genesinay
R.J. Sysko
Original Assignee
Pfizer Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Inc. filed Critical Pfizer Inc.
Publication of YU42489A publication Critical patent/YU42489A/xx
Publication of YU47207B publication Critical patent/YU47207B/sh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/26—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings condensed with carbocyclic rings or ring systems
    • C07D237/30—Phthalazines
    • C07D237/34—Phthalazines with nitrogen atoms directly attached to carbon atoms of the nitrogen-containing ring, e.g. hydrazine radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/26—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings condensed with carbocyclic rings or ring systems
    • C07D237/30—Phthalazines
    • C07D237/32—Phthalazines with oxygen atoms directly attached to carbon atoms of the nitrogen-containing ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Separation Of Suspended Particles By Flocculating Agents (AREA)
  • Steroid Compounds (AREA)
  • Furan Compounds (AREA)

Abstract

POSTUPAK ZA DOBIJANJE ESTARSKIH DERIVATA FTALAZINSIRĆETNE KISELINE I ODGOVARAJUĆEG INTERMEDIJARA, formule: naznačen time, što jedinjenje formule reaguje sa hidrazinom u prisustvu rastvarača kao što je niži alkil alkohol, na temperaturi nižoj od oko 40В°C. Postupak za dobijanje jedinjenja formule u kojoj R predstavlja (C1-C4) alkil, naznačen time, što jedinjenje formule reaguje sa hidrazinom u prisustvu rastvarača kao što je niži alkil alkohol, na temperaturi nižoj od 40В°C, što se iz reakcione smese uklanja hidrazin i što preostala smeša reaguje sa kiselinom u prisustvu rastvarača, pri čemu rastvarač ima formulu ROH u kojoj je R kao što je prethodno definisano, i što se doda dodatna količina kiseline. Prijava sadrži još 3 nezavisna i 15 zavisnih zahteva.
YU42489A 1988-02-29 1989-02-27 Postupak za dobijanje estarskih derivata ftalazinsirćetne kiseline i odgovarajućeg intermedijara YU47207B (sh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/161,540 US4904782A (en) 1988-02-29 1988-02-29 Process for the production of phthalazineacetic acid ester derivatives and a novel intermediate

Publications (2)

Publication Number Publication Date
YU42489A YU42489A (en) 1990-12-31
YU47207B true YU47207B (sh) 1995-01-31

Family

ID=22581597

Family Applications (1)

Application Number Title Priority Date Filing Date
YU42489A YU47207B (sh) 1988-02-29 1989-02-27 Postupak za dobijanje estarskih derivata ftalazinsirćetne kiseline i odgovarajućeg intermedijara

Country Status (26)

Country Link
US (1) US4904782A (sh)
EP (1) EP0331314B1 (sh)
JP (1) JPH029867A (sh)
KR (1) KR910000664B1 (sh)
CN (1) CN1021222C (sh)
AT (1) ATE103904T1 (sh)
AU (1) AU610347B2 (sh)
CA (1) CA1308412C (sh)
DD (1) DD290190A5 (sh)
DE (1) DE68914309T2 (sh)
DK (1) DK93089A (sh)
EG (1) EG18597A (sh)
FI (1) FI890929A (sh)
HU (1) HU202845B (sh)
IE (1) IE890643L (sh)
IL (1) IL89360A (sh)
MX (1) MX15078A (sh)
MY (1) MY104951A (sh)
NO (1) NO890815L (sh)
NZ (1) NZ228142A (sh)
PL (4) PL159836B1 (sh)
PT (1) PT89871B (sh)
RU (1) RU1830066C (sh)
SU (3) SU1757465A3 (sh)
YU (1) YU47207B (sh)
ZA (1) ZA891486B (sh)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1991009019A1 (en) * 1989-12-15 1991-06-27 Pfizer Inc. Substituted oxophthalazinyl acetic acids and analogs thereof
EP0982306A3 (en) * 1998-08-21 2000-07-05 Pfizer Products Inc. Polymorph of zopolrestat monohydrate
CN116970317A (zh) * 2023-03-20 2023-10-31 安徽庆丰涂料科技有限公司 可呼吸的负离子抗菌涂料及其加工工艺

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE47592B1 (en) * 1977-12-29 1984-05-02 Ici Ltd Enzyme inhibitory phthalazin-4-ylacetic acid derivatives, pharmaceutical compositions thereof,and process for their manufacture
CA1143733A (en) * 1979-07-31 1983-03-29 Masao Yoshida Producing 7-alkoxycarbonyl-6,8-dimethyl-4- hydroxymethyl-1-phthalazone and intermediates
ES2032749T3 (es) * 1985-11-07 1993-03-01 Pfizer Inc. Acidos oxoftalazinil-aceticos heterociclicos.
JPH0676391B2 (ja) * 1987-06-09 1994-09-28 フアイザー・インコーポレイテツド ベンゾチアゾール等の複素環側鎖を有するオキソフタラジニル酢酸類の製造方法

Also Published As

Publication number Publication date
KR910000664B1 (ko) 1991-01-31
DE68914309T2 (de) 1994-07-14
SU1757465A3 (ru) 1992-08-23
HU202845B (en) 1991-04-29
PT89871A (pt) 1989-10-04
KR890012975A (ko) 1989-09-20
DE68914309D1 (de) 1994-05-11
PL159837B1 (pl) 1993-01-29
RU1830066C (ru) 1993-07-23
ATE103904T1 (de) 1994-04-15
MX15078A (es) 1993-05-01
NO890815L (no) 1989-08-30
MY104951A (en) 1994-07-30
PL159784B1 (en) 1993-01-29
AU3077289A (en) 1989-08-31
US4904782A (en) 1990-02-27
JPH029867A (ja) 1990-01-12
EG18597A (en) 1993-08-30
CN1036953A (zh) 1989-11-08
FI890929A0 (fi) 1989-02-27
DK93089A (da) 1989-08-30
FI890929A (fi) 1989-08-30
DD290190A5 (de) 1991-05-23
IL89360A (en) 1994-08-26
EP0331314B1 (en) 1994-04-06
EP0331314A3 (en) 1991-06-12
PL160288B1 (pl) 1993-02-26
IL89360A0 (en) 1989-09-10
YU42489A (en) 1990-12-31
SU1766256A3 (ru) 1992-09-30
DK93089D0 (da) 1989-02-27
PT89871B (pt) 1994-04-29
EP0331314A2 (en) 1989-09-06
CA1308412C (en) 1992-10-06
NZ228142A (en) 1990-10-26
CN1021222C (zh) 1993-06-16
IE890643L (en) 1989-08-29
NO890815D0 (no) 1989-02-27
PL277923A1 (en) 1989-09-04
SU1736340A3 (ru) 1992-05-23
PL159836B1 (pl) 1993-01-29
ZA891486B (en) 1990-10-31
AU610347B2 (en) 1991-05-16
HUT51259A (en) 1990-04-28

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