YU44821B - Process for obtaiing new pyridyl derivatives - Google Patents

Process for obtaiing new pyridyl derivatives

Info

Publication number
YU44821B
YU44821B YU221/83A YU22183A YU44821B YU 44821 B YU44821 B YU 44821B YU 221/83 A YU221/83 A YU 221/83A YU 22183 A YU22183 A YU 22183A YU 44821 B YU44821 B YU 44821B
Authority
YU
Yugoslavia
Prior art keywords
hydrogen
obtaiing
compounds
nitrogen
symptomatic treatment
Prior art date
Application number
YU221/83A
Other languages
English (en)
Other versions
YU22183A (en
Inventor
G G Coker
J W A Findlay
Original Assignee
Wellcome Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wellcome Found filed Critical Wellcome Found
Priority to SI8310221A priority Critical patent/SI8310221A8/sl
Publication of YU22183A publication Critical patent/YU22183A/xx
Publication of YU44821B publication Critical patent/YU44821B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/79—Acids; Esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/485—Morphinan derivatives, e.g. morphine, codeine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/55—Acids; Esters
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/56—Amides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/61—Halogen atoms or nitro radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D295/155—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Emergency Medicine (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Superconductors And Manufacturing Methods Therefor (AREA)
  • Peptides Or Proteins (AREA)
  • Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Polyoxymethylene Polymers And Polymers With Carbon-To-Carbon Bonds (AREA)
  • Polyesters Or Polycarbonates (AREA)
YU221/83A 1982-02-04 1983-02-01 Process for obtaiing new pyridyl derivatives YU44821B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
SI8310221A SI8310221A8 (en) 1982-02-04 1983-02-01 Process for obtaining new pyridil compounds

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB8203261 1982-02-04
GB8229705 1982-10-18

Publications (2)

Publication Number Publication Date
YU22183A YU22183A (en) 1986-02-28
YU44821B true YU44821B (en) 1991-02-28

Family

ID=26281898

Family Applications (1)

Application Number Title Priority Date Filing Date
YU221/83A YU44821B (en) 1982-02-04 1983-02-01 Process for obtaiing new pyridyl derivatives

Country Status (32)

Country Link
EP (2) EP0249950B1 (ko)
JP (2) JPS6479153A (ko)
KR (6) KR880001466B1 (ko)
AT (2) ATE64596T1 (ko)
AU (1) AU555083B2 (ko)
BG (6) BG41822A3 (ko)
CA (2) CA1249830A (ko)
CS (1) CS235306B2 (ko)
CY (1) CY1627A (ko)
DD (1) DD209446A5 (ko)
DE (2) DE3379654D1 (ko)
DK (1) DK164662C (ko)
ES (6) ES519491A0 (ko)
FI (1) FI82450C (ko)
GB (1) GB2114565B (ko)
GR (1) GR77407B (ko)
HK (1) HK25892A (ko)
HU (1) HU189223B (ko)
IE (1) IE54600B1 (ko)
IL (3) IL78419A (ko)
MC (1) MC1498A1 (ko)
NL (1) NL930057I2 (ko)
NO (2) NO162556C (ko)
NZ (1) NZ203171A (ko)
PH (1) PH21348A (ko)
PL (6) PL140812B1 (ko)
PT (1) PT76192B (ko)
SG (1) SG106091G (ko)
SI (1) SI8310221A8 (ko)
SU (1) SU1301312A3 (ko)
UY (1) UY23404A1 (ko)
YU (1) YU44821B (ko)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4562258A (en) * 1982-02-04 1985-12-31 Findlay John W A 6-[3-Amino-1-(4-tolyl)prop-1E-enyl]pyridine-2-carboxylic acid derivatives having antihistaminic activity
US4610995A (en) * 1984-07-27 1986-09-09 Coker Geoffrey G Certain 1,1-diaryl-propenyl-3-(1-pyrrolidino-2-carboxylic acids, derivatives thereof and their anti-histaminic properties
LU86387A1 (fr) * 1986-04-04 1987-12-07 Oreal Composes aromatiques,leur procede de preparation et leur utilisation en medicine humaine et veterinaire et en cosmetique
GB8707416D0 (en) * 1987-03-27 1987-04-29 Wellcome Found Pharmaceutical formulations
DE3711866A1 (de) * 1987-04-08 1988-10-27 Hoechst Ag Synthese von peptidamiden mittels festphasenmethode unter verwendung von saeurelabilen ankergruppen
IL94768A (en) * 1989-06-19 1995-08-31 Wellcome Found Use of Reliable History Transformed by Aril for the Preparation of Pharmaceuticals
GB8914060D0 (en) * 1989-06-19 1989-08-09 Wellcome Found Agents for potentiating the effects of antitumour agents and combating multiple drug resistance
GB8914040D0 (en) * 1989-06-19 1989-08-09 Wellcome Found Agents for potentiating the effects of antitumour agents and combating multiple drug resistance
FR2711651B1 (fr) * 1993-10-28 1995-12-22 Adir Nouveaux analogues cyclisés de métabolites d'acides gras, leur procédé de préparation et les compositions pharmaceutiques les renfermant.
US5420866A (en) * 1994-03-29 1995-05-30 Scientific-Atlanta, Inc. Methods for providing conditional access information to decoders in a packet-based multiplexed communications system
GB9508748D0 (en) * 1995-04-28 1995-06-14 British Biotech Pharm Benzimidazole derivatives
JPH11510180A (ja) * 1995-08-05 1999-09-07 ブリティッシュ バイオテック ファーマシューティカルズ リミテッド イミダゾピリジン誘導体
IT1277597B1 (it) * 1995-09-15 1997-11-11 Smithkline Beecham Spa Derivati di diarilalchenilammina
CN101838235B (zh) * 2009-06-12 2013-08-07 重庆华邦制药有限公司 3-苯基-3＇-吡啶基丙烯胺类化合物及其合成方法
CN103124723A (zh) * 2010-09-23 2013-05-29 先正达参股股份有限公司 新颖的杀微生物剂
CN104254589B (zh) 2012-04-23 2016-06-15 沙特基础工业公司 基于太阳能的连续方法和用于通过相应的烷烃脱氢生产烯烃的反应器系统

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2567245A (en) * 1948-05-10 1951-09-11 Schering Corp Aryl-(2-pyridyl)-amino alkanes and their production
DE1227464B (de) * 1951-09-10 1966-10-27 Wellcome Found Verfahren zur Herstellung der trans-Form des neuen 1-(4'-Methylphenyl)-1-(2''-pyridyl)-3-pyrrolidinopropens-(1)
FR1228801A (fr) * 1954-05-03 1960-09-02 Farbwerke Hoechst Ag Vomals Me Procédé de préparation de composés tertio-amino carboxyliques et des composés tertio-amino cétoniques correspondants
FR2197583B1 (ko) * 1972-09-07 1975-10-17 Rhone Poulenc Ind

Also Published As

Publication number Publication date
AU1098283A (en) 1983-08-11
PL140708B1 (en) 1987-05-30
SG106091G (en) 1992-03-20
PT76192A (en) 1983-03-01
PT76192B (en) 1986-01-24
EP0085959A2 (en) 1983-08-17
DD209446A5 (de) 1984-05-09
SI8310221A8 (en) 1995-10-31
DK43683D0 (da) 1983-02-03
BG41822A3 (en) 1987-08-14
ES523415A0 (es) 1984-10-01
FI830380L (fi) 1983-08-05
ES8500235A1 (es) 1984-10-01
NL930057I1 (nl) 1993-09-01
ES8500233A1 (es) 1984-10-01
ES523418A0 (es) 1984-10-01
GR77407B (ko) 1984-09-13
KR840003628A (ko) 1984-09-15
EP0085959B1 (en) 1989-04-19
PL240412A1 (en) 1985-01-30
EP0249950A1 (en) 1987-12-23
PL140811B1 (en) 1987-05-30
KR880001466B1 (ko) 1988-08-11
KR870001915B1 (ko) 1987-10-22
ES523417A0 (es) 1984-10-01
NL930057I2 (nl) 1994-02-16
UY23404A1 (es) 1992-10-19
CA1275102A (en) 1990-10-09
AU555083B2 (en) 1986-09-11
DK43683A (da) 1983-08-05
PL140809B1 (en) 1987-05-30
CA1249830A (en) 1989-02-07
ES523414A0 (es) 1984-10-01
EP0249950B1 (en) 1991-06-19
NO874330L (no) 1983-08-05
ATE64596T1 (de) 1991-07-15
JPH0251897B2 (ko) 1990-11-08
IE54600B1 (en) 1989-12-06
CS235306B2 (en) 1985-05-15
PL245842A1 (en) 1985-01-30
PL245845A1 (en) 1985-01-30
PL140812B1 (en) 1987-05-30
ES8500231A1 (es) 1984-10-01
DK164662B (da) 1992-07-27
YU22183A (en) 1986-02-28
ES8403872A1 (es) 1984-04-01
PL141639B1 (en) 1987-08-31
JPS6479153A (en) 1989-03-24
JPH01301661A (ja) 1989-12-05
PL245843A1 (en) 1985-01-30
JPH0468B2 (ko) 1992-01-06
PL140810B1 (en) 1987-05-30
DE3382321D1 (de) 1991-07-25
NO172341B (no) 1993-03-29
NO830368L (no) 1983-08-05
FI82450C (fi) 1991-03-11
BG42003A3 (en) 1987-09-15
NZ203171A (en) 1986-12-05
IL67829A (en) 1988-06-30
BG42185A3 (en) 1987-10-15
IE830213L (en) 1983-08-04
DE3379654D1 (en) 1989-05-24
ES8500232A1 (es) 1984-10-01
MC1498A1 (fr) 1983-11-17
IL78419A0 (en) 1986-08-31
GB2114565A (en) 1983-08-24
HU189223B (en) 1986-06-30
PL245844A1 (en) 1985-01-30
EP0085959A3 (en) 1984-07-18
KR870001916B1 (ko) 1987-10-22
IL78419A (en) 1989-01-31
GB8302971D0 (en) 1983-03-09
ATE42282T1 (de) 1989-05-15
SU1301312A3 (ru) 1987-03-30
ES8500234A1 (es) 1984-10-01
DK164662C (da) 1992-12-14
HK25892A (en) 1992-04-16
BG41821A3 (en) 1987-08-14
KR870001927B1 (ko) 1987-10-22
CY1627A (en) 1992-07-10
FI82450B (fi) 1990-11-30
GB2114565B (en) 1985-06-26
ES523416A0 (es) 1984-10-01
BG42004A3 (en) 1987-09-15
NO172341C (no) 1993-07-07
FI830380A0 (fi) 1983-02-03
NO162556B (no) 1989-10-09
PL245841A1 (en) 1985-01-30
BG42005A3 (en) 1987-09-15
NO874330D0 (no) 1987-10-16
NO162556C (no) 1990-01-17
IL67829A0 (en) 1983-06-15
PH21348A (en) 1987-10-13
ES519491A0 (es) 1984-04-01
KR870001918B1 (ko) 1987-10-22
KR870001917B1 (ko) 1987-10-22
CA1275102C (ko) 1990-10-09

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Publication Publication Date Title
YU22183A (en) Process for obtaiing new pyridyl derivatives