YU42485B - Process for obtaining cephalosporin derivatives - Google Patents

Process for obtaining cephalosporin derivatives

Info

Publication number
YU42485B
YU42485B YU1233/79A YU123379A YU42485B YU 42485 B YU42485 B YU 42485B YU 1233/79 A YU1233/79 A YU 1233/79A YU 123379 A YU123379 A YU 123379A YU 42485 B YU42485 B YU 42485B
Authority
YU
Yugoslavia
Prior art keywords
triazin
methyl
group
cephalosporin derivatives
dioxo
Prior art date
Application number
YU1233/79A
Other languages
English (en)
Other versions
YU123379A (en
Inventor
M Montavon
R Reiner
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CH588278A external-priority patent/CH641468A5/de
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Priority to SI7911233A priority Critical patent/SI7911233A8/sl
Publication of YU123379A publication Critical patent/YU123379A/xx
Publication of YU42485B publication Critical patent/YU42485B/xx
Priority to HRP-1233/79A priority patent/HRP930529B1/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D501/00Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/207-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/247-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/36Methylene radicals, substituted by sulfur atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Mutual Connection Of Rods And Tubes (AREA)
  • Reinforcement Elements For Buildings (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Fats And Perfumes (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Steroid Compounds (AREA)
YU1233/79A 1978-05-30 1979-05-25 Process for obtaining cephalosporin derivatives YU42485B (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
SI7911233A SI7911233A8 (sl) 1978-05-30 1979-05-25 Postopek za pripravo derivatov cefalosporina
HRP-1233/79A HRP930529B1 (en) 1978-05-30 1993-03-26 Process for the preparation of cephalosphorine derivatives

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH588278A CH641468A5 (de) 1978-05-30 1978-05-30 Cephemderivate.
CH224879 1979-03-08

Publications (2)

Publication Number Publication Date
YU123379A YU123379A (en) 1983-04-30
YU42485B true YU42485B (en) 1988-10-31

Family

ID=25689901

Family Applications (3)

Application Number Title Priority Date Filing Date
YU1233/79A YU42485B (en) 1978-05-30 1979-05-25 Process for obtaining cephalosporin derivatives
YU745/85A YU45257B (en) 1978-05-30 1985-05-06 Process for obtaining salt-hydrates derivatives of cephalosporine
YU744/85A YU45256B (en) 1978-05-30 1985-05-06 Process for obtaining derivatives of cephalosporine

Family Applications After (2)

Application Number Title Priority Date Filing Date
YU745/85A YU45257B (en) 1978-05-30 1985-05-06 Process for obtaining salt-hydrates derivatives of cephalosporine
YU744/85A YU45256B (en) 1978-05-30 1985-05-06 Process for obtaining derivatives of cephalosporine

Country Status (40)

Country Link
EP (2) EP0045525B1 (https=)
JP (2) JPS54157596A (https=)
AT (3) AT367764B (https=)
BG (1) BG50163A3 (https=)
BR (1) BR7903368A (https=)
CA (1) CA1141373A (https=)
CS (1) CS219254B2 (https=)
CU (1) CU35088A (https=)
CY (1) CY1182A (https=)
DD (1) DD143911A5 (https=)
DE (4) DE2966946D1 (https=)
DK (1) DK149282C (https=)
EG (1) EG14153A (https=)
ES (2) ES480990A1 (https=)
FI (1) FI65434C (https=)
FR (2) FR2427337A1 (https=)
GB (2) GB2022090B (https=)
GR (1) GR72242B (https=)
HK (1) HK31383A (https=)
HU (1) HU183089B (https=)
IE (1) IE49047B1 (https=)
IL (1) IL57392A (https=)
IS (1) IS1203B6 (https=)
IT (1) IT1121517B (https=)
KE (1) KE3268A (https=)
LU (1) LU81325A1 (https=)
MC (1) MC1259A1 (https=)
MT (1) MTP845B (https=)
MY (1) MY8400127A (https=)
NL (1) NL7904083A (https=)
NO (1) NO159797C (https=)
NZ (1) NZ190532A (https=)
OA (1) OA06263A (https=)
PH (1) PH15148A (https=)
PL (1) PL122458B1 (https=)
PT (1) PT69698A (https=)
RO (1) RO77560A (https=)
SE (1) SE437522B (https=)
SG (1) SG10483G (https=)
YU (3) YU42485B (https=)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI67385C (fi) * 1979-11-21 1985-03-11 Hoffmann La Roche Foerfarande foer framstaellning av (6r 7r)-7-(2-(2-amino-4-tiazolyl)-2-(z-metoxiimino)acetamido)-3-cefem-4-karboxylsyraderivat
US4349672A (en) * 1979-11-29 1982-09-14 Hoffmann-La Roche Inc. Cephalosporin derivatives
CA1177823A (en) * 1980-03-25 1984-11-13 Andre Furlenmeier Cephalosporin derivatives
CA1154009A (en) * 1980-03-25 1983-09-20 Roland Reiner Cephalosporin derivatives
GR75706B (https=) * 1980-06-30 1984-08-02 Sanofi Sa
US4308267A (en) 1980-07-03 1981-12-29 Smithkline Corporation 7-[2-Alkoxyimino-2-(amino-thiazole)acetamido]-3-[1-(sulfaminoalkly)tetrazolthiomethyl]cephalosporins
DK379581A (da) * 1980-10-06 1982-04-07 Hoffmann La Roche Fremgangsmaade til fremstilling af acylderivater
FR2494278A1 (fr) * 1980-11-20 1982-05-21 Rhone Poulenc Ind Nouveaux derives de la cephalosporine, leurs preparations et les medicaments qui les contiennent
EP0058250A3 (de) * 1981-02-17 1983-08-17 F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft Cephalosporinderivate, deren Herstellung und entsprechende pharmazeutische Präparate
EP0185220A3 (de) * 1984-12-19 1987-09-02 F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft Zwischenprodukte zur Herstellung von Cephalosporinen
CA1296012C (en) 1986-03-19 1992-02-18 Susumu Nakagawa 6,7-dihydroxy-isoquinoline derivatives
RU2021274C1 (ru) 1991-05-17 1994-10-15 Польска Акадэмия Наук Институт Хэмии Органичнэй Способ получения аминотиазолильных производных цефалоспорина
KR950014571B1 (ko) * 1991-11-18 1995-12-08 제일제당주식회사 세펨 유도체의 제조방법
AT398764B (de) * 1992-01-28 1995-01-25 Lek Tovarna Farmacevtskih Verfahren zur herstellung von ceftriaxondinatrium-salzhemiheptahydrat
AT399877B (de) * 1992-02-20 1995-08-25 Biochemie Gmbh Neues verfahren zur herstellung von ceftriaxon
KR100197788B1 (ko) * 1995-06-30 1999-06-15 김충환 세펨 유도체의 제조방법
DE102011117421A1 (de) 2011-11-02 2013-05-02 Hans-Peter Gabel Pharmazeutische Zusammensetzung zur Behandlung von Borreliose
RU2504548C1 (ru) * 2012-09-28 2014-01-20 Федеральное Государственное Автономное Образовательное Учреждение Высшего Профессионального Образования "Сибирский Федеральный Университет" (Сфу) ПРОИЗВОДНОЕ β-ЛАКТАМНОГО АНТИБИОТИКА ЦЕФТРИАКСОНА

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH609989A5 (en) * 1974-06-21 1979-03-30 Hoffmann La Roche Process for the preparation of acyl derivatives
CA1100129A (en) * 1974-08-02 1981-04-28 William H.W. Lunn Cephalosporin compounds
FR2345153A1 (fr) * 1976-03-25 1977-10-21 Roussel Uclaf Nouvelles alcoyloximes derivees de l'acide 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments
DK162391C (da) 1976-04-12 1992-03-09 Fujisawa Pharmaceutical Co Analogifremgangsmaade til fremstilling af syn-isomerer af 3,7-disubstituerede 3-cephem-4-carboxylsyreforbindelser
DE2760484C2 (https=) * 1976-04-14 1992-12-03 Takeda Chemical Industries, Ltd., Osaka, Jp
JPS5329936A (en) * 1976-08-31 1978-03-20 Takeda Chem Ind Ltd Antibiotic composition
NL7805715A (nl) * 1977-06-03 1978-12-05 Hoffmann La Roche Werkwijze voor het bereiden van acylderivaten.
US4200745A (en) * 1977-12-20 1980-04-29 Eli Lilly And Company 7[2-(2-Aminothiazol-4-yl)-2-alkoxyimino]acetamido 3[4-alkyl-5-oxo-6-hydroxy-3,4 dihydro 1,2,4-triazin 3-yl]thio methyl cephalosporins

Also Published As

Publication number Publication date
NL7904083A (nl) 1979-12-04
YU45257B (en) 1992-05-28
SE437522B (sv) 1985-03-04
NO791776L (no) 1979-12-03
OA06263A (fr) 1981-06-30
FR2427337A1 (fr) 1979-12-28
FR2509312B1 (https=) 1984-06-29
IE49047B1 (en) 1985-07-24
EP0045525A2 (de) 1982-02-10
BG50163A3 (bg) 1992-05-15
NO159797B (no) 1988-10-31
IL57392A0 (en) 1979-09-30
YU74485A (en) 1987-12-31
DE2922036A1 (de) 1979-12-06
GR72242B (https=) 1983-10-04
ES488687A0 (es) 1980-12-16
IT7923049A0 (it) 1979-05-28
EP0045525B1 (de) 1984-04-25
ATA390479A (de) 1981-12-15
PH15148A (en) 1982-08-24
NO159797C (no) 1989-02-08
DE2922036C2 (de) 1983-02-17
EG14153A (en) 1983-03-31
GB2099418B (en) 1983-06-02
RO77560A (ro) 1982-04-12
SE7904682L (sv) 1979-12-01
FI65434B (fi) 1984-01-31
EP0005830B1 (de) 1982-09-22
DE2954159C2 (de) 1983-10-06
IE791041L (en) 1979-11-30
HU183089B (en) 1984-04-28
DD143911A5 (de) 1980-09-17
SG10483G (en) 1983-12-16
AT367764B (de) 1982-07-26
CA1141373A (en) 1983-02-15
ATE1586T1 (de) 1982-10-15
MC1259A1 (fr) 1980-01-14
DK222679A (da) 1979-12-01
KE3268A (en) 1983-05-13
JPS613355B2 (https=) 1986-01-31
FI791703A7 (fi) 1979-12-01
ATE7229T1 (de) 1984-05-15
CS219254B2 (en) 1983-03-25
ES8101606A1 (es) 1980-12-16
GB2099418A (en) 1982-12-08
PL215972A1 (https=) 1980-02-11
YU123379A (en) 1983-04-30
BR7903368A (pt) 1979-12-11
EP0005830A1 (de) 1979-12-12
FR2509312A1 (fr) 1983-01-14
GB2022090A (en) 1979-12-12
DE2963720D1 (en) 1982-11-04
IS1203B6 (is) 1986-03-24
IL57392A (en) 1982-05-31
IT1121517B (it) 1986-04-02
JPS6016994A (ja) 1985-01-28
CU35088A (en) 1982-08-24
JPS54157596A (en) 1979-12-12
EP0045525A3 (en) 1982-02-17
PL122458B1 (en) 1982-07-31
YU74585A (en) 1987-12-31
DK149282C (da) 1986-09-01
CY1182A (en) 1983-10-07
AU524230B2 (en) 1982-09-09
GB2022090B (en) 1982-12-15
FI65434C (fi) 1984-05-10
JPS613795B2 (https=) 1986-02-04
HK31383A (en) 1983-09-02
MTP845B (en) 1980-07-21
LU81325A1 (de) 1980-12-16
ES480990A1 (es) 1980-08-16
PT69698A (en) 1979-06-01
YU45256B (en) 1992-05-28
IS2490A7 (is) 1979-12-01
NZ190532A (en) 1983-03-15
AU4736679A (en) 1979-12-06
MY8400127A (en) 1984-12-31
DK149282B (da) 1986-04-21
DE2966946D1 (en) 1984-05-30

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Publication Publication Date Title
YU42485B (en) Process for obtaining cephalosporin derivatives