YU158591A - Substituirani 4-amino-3-piridinoli i postupak za njihovo dobijanje - Google Patents

Substituirani 4-amino-3-piridinoli i postupak za njihovo dobijanje

Info

Publication number
YU158591A
YU158591A YU158591A YU158591A YU158591A YU 158591 A YU158591 A YU 158591A YU 158591 A YU158591 A YU 158591A YU 158591 A YU158591 A YU 158591A YU 158591 A YU158591 A YU 158591A
Authority
YU
Yugoslavia
Prior art keywords
lower alkyl
hydrogen
amino
substituted
pyridinols
Prior art date
Application number
YU158591A
Other languages
English (en)
Serbo-Croatian (sh)
Inventor
G.M. Shutske
K.Y. Kapples
Y.D. Tomer
N.Y. Hrib
J.G. Jurcak
Original Assignee
Hoechst-Roussel Pharmaceuticals Incorporated
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst-Roussel Pharmaceuticals Incorporated filed Critical Hoechst-Roussel Pharmaceuticals Incorporated
Publication of YU158591A publication Critical patent/YU158591A/sh

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/26Radicals substituted by halogen atoms or nitro radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72Nitrogen atoms
    • C07D213/74Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Surface Treatment Of Glass (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
YU158591A 1990-09-27 1991-09-26 Substituirani 4-amino-3-piridinoli i postupak za njihovo dobijanje YU158591A (sh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US58911390A 1990-09-27 1990-09-27

Publications (1)

Publication Number Publication Date
YU158591A true YU158591A (sh) 1994-12-28

Family

ID=24356648

Family Applications (1)

Application Number Title Priority Date Filing Date
YU158591A YU158591A (sh) 1990-09-27 1991-09-26 Substituirani 4-amino-3-piridinoli i postupak za njihovo dobijanje

Country Status (22)

Country Link
US (3) US5821239A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
EP (1) EP0477903B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
JP (1) JP3090511B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
KR (1) KR100215357B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AT (1) ATE136297T1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AU (1) AU637720B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CA (1) CA2052433C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CZ (1) CZ282002B6 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DE (1) DE69118470T2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DK (1) DK0477903T3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ES (1) ES2085940T3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
FI (1) FI914504A7 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
GR (1) GR3019742T3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
HU (1) HUT60247A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IE (1) IE73874B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IL (1) IL99581A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NO (1) NO913778L (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NZ (1) NZ239935A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
PT (1) PT99073B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
TW (1) TW200462B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
YU (1) YU158591A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ZA (1) ZA917692B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6218383B1 (en) 1998-08-07 2001-04-17 Targacept, Inc. Pharmaceutical compositions for the prevention and treatment of central nervous system disorders
FR2813891B1 (fr) * 2000-09-14 2005-01-14 Immunotech Sa Reactif multifonctionnel pour erythrocytes mettant en jeu des carbamates et applications
DE10102791B4 (de) * 2001-01-22 2004-04-15 Ifm Electronic Gmbh Elektrischer Meßumformer
AU2002351731A1 (en) * 2001-12-14 2003-06-30 Novo Nordisk A/S Compounds and uses thereof for decreasing activity of hormone-sensitive lipase
KR100443983B1 (ko) 2002-01-15 2004-08-09 삼성전자주식회사 냉장고
US8007826B2 (en) 2003-12-11 2011-08-30 Acorda Therapeutics, Inc. Sustained release aminopyridine composition
US8354437B2 (en) 2004-04-09 2013-01-15 Acorda Therapeutics, Inc. Method of using sustained release aminopyridine compositions
TW200640864A (en) 2005-02-17 2006-12-01 Astellas Pharma Inc Pyridyl non-aromatic nitrogenated heterocyclic-1-carboxylate ester derivative
BRPI0903914A2 (pt) * 2008-09-10 2015-07-21 Acorda Therapeutics Inc Uso de um composto, método para analisar a eficácia de uma composição de liberação prolongada, e, composição farmacêutica.
CN109662964A (zh) 2010-02-09 2019-04-23 约翰斯.霍普金斯大学 用于改善认知功能的方法和组合物
WO2014078568A1 (en) 2012-11-14 2014-05-22 The Johns Hopkins University Methods and compositions for treating schizophrenia
KR102171152B1 (ko) 2012-12-13 2020-10-29 하. 룬드벡 아크티에셀스카브 보르티옥세틴 및 도네페질을 포함하는 조성물
WO2014144663A1 (en) 2013-03-15 2014-09-18 The Johns Hopkins University Methods and compositions for improving cognitive function
CN105142623A (zh) 2013-03-15 2015-12-09 艾吉因生物股份有限公司 用于改善认知功能的方法和组合物
NZ738682A (en) 2015-05-22 2022-01-28 Agenebio Inc Extended release pharmaceutical compositions of levetiracetam
JP6899120B2 (ja) * 2016-10-12 2021-07-07 株式会社ナノエッグ アセチルコリンエステラーゼ(AChE)阻害剤

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4179563A (en) * 1978-05-19 1979-12-18 Warner-Lambert Company 3-Aryloxy-substituted-aminopyridines and methods for their production
US4734275A (en) * 1983-08-19 1988-03-29 Research Corporation Anti-curare agents
DE3514073A1 (de) * 1985-04-18 1986-10-23 Hoechst Ag, 6230 Frankfurt Mehrfach substituierte pyridin-1-oxide, verfahren zu ihrer herstellung, die sie enthaltenden arzneimittel und ihre verwendung
US4735958A (en) * 1986-12-22 1988-04-05 Warner-Lambert Company Trans-6-[2-[2-(substituted-phenyl)-3- (or 4-) heteroaryl-5-substituted-1H-pyrrol-1-yl]-ethyl]tetrahydro-4-hydroxy-2H-pyran-2-one inhibitors of cholesterol biosynthesis
US4831044A (en) * 1987-10-29 1989-05-16 Ici Americas Inc. Fungicidal pyridyl cyclopropane carboxamidines
US4994473A (en) * 1987-11-17 1991-02-19 Ici Americas Inc. Pyridyl containing insecticides
EP0361489A3 (en) * 1988-09-30 1991-06-12 Chugai Seiyaku Kabushiki Kaisha Novel 3,4-diaminoquinoline and pyridine compounds
EP0369388B1 (en) * 1988-11-16 1993-05-19 Hoechst-Roussel Pharmaceuticals Incorporated Hydroxy-1,2,3,4-tetrahydroaminoacridines, a process for their preparation and their use as medicaments
US4931457B1 (en) * 1989-06-28 1993-11-16 Hoechst-Roussel Pharmaceuticals Incorporated Naphthylamino-and naphthyloxy-pyridineamin compounds useful as topical antiinflammatory agents for the treatment of skin disorders

Also Published As

Publication number Publication date
NO913778D0 (no) 1991-09-26
FI914504A0 (fi) 1991-09-25
US5866565A (en) 1999-02-02
IL99581A0 (en) 1992-08-18
TW200462B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1993-02-21
EP0477903A2 (en) 1992-04-01
ZA917692B (en) 1992-05-27
GR3019742T3 (en) 1996-07-31
DK0477903T3 (da) 1996-07-29
IE913389A1 (en) 1992-04-08
PT99073A (pt) 1992-08-31
IL99581A (en) 1995-07-31
ES2085940T3 (es) 1996-06-16
CA2052433C (en) 2003-04-15
NZ239935A (en) 1995-07-26
AU8475691A (en) 1992-04-02
DE69118470T2 (de) 1996-09-19
FI914504A7 (fi) 1992-03-28
AU637720B2 (en) 1993-06-03
KR100215357B1 (ko) 1999-08-16
JP3090511B2 (ja) 2000-09-25
HUT60247A (en) 1992-08-28
PT99073B (pt) 1999-02-26
CA2052433A1 (en) 1992-03-28
JPH04261157A (ja) 1992-09-17
ATE136297T1 (de) 1996-04-15
EP0477903A3 (en) 1992-08-05
IE73874B1 (en) 1997-07-02
US5821239A (en) 1998-10-13
CS293691A3 (en) 1992-04-15
DE69118470D1 (de) 1996-05-09
US5869480A (en) 1999-02-09
KR920006318A (ko) 1992-04-27
NO913778L (no) 1992-03-30
EP0477903B1 (en) 1996-04-03
CZ282002B6 (cs) 1997-04-16
HU913075D0 (en) 1992-01-28

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