FI914504A0 - Substituerade 4-amino-3-pyridinoler, foerfarande foer deras framstaellning och deras anvaendning som laekemedel. - Google Patents

Substituerade 4-amino-3-pyridinoler, foerfarande foer deras framstaellning och deras anvaendning som laekemedel.

Info

Publication number
FI914504A0
FI914504A0 FI914504A FI914504A FI914504A0 FI 914504 A0 FI914504 A0 FI 914504A0 FI 914504 A FI914504 A FI 914504A FI 914504 A FI914504 A FI 914504A FI 914504 A0 FI914504 A0 FI 914504A0
Authority
FI
Finland
Prior art keywords
deras
pyridinoler
substituer
amino
loweralkyl
Prior art date
Application number
FI914504A
Other languages
English (en)
Other versions
FI914504A (fi
Inventor
Gregory Michael Shutske
Kevin James Kapples
John Dick Tomer
Nicholas Joseph Hrib
John Gerard Jurcak
Original Assignee
Hoechst Roussel Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Roussel Pharma filed Critical Hoechst Roussel Pharma
Publication of FI914504A0 publication Critical patent/FI914504A0/fi
Publication of FI914504A publication Critical patent/FI914504A/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/26—Radicals substituted by halogen atoms or nitro radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hospice & Palliative Care (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Psychiatry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Surface Treatment Of Glass (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
FI914504A 1990-09-27 1991-09-25 Substituerade 4-amino-3-pyridinoler, foerfarande foer deras framstaellning och deras anvaendning som laekemedel. FI914504A (fi)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US58911390A 1990-09-27 1990-09-27

Publications (2)

Publication Number Publication Date
FI914504A0 true FI914504A0 (fi) 1991-09-25
FI914504A FI914504A (fi) 1992-03-28

Family

ID=24356648

Family Applications (1)

Application Number Title Priority Date Filing Date
FI914504A FI914504A (fi) 1990-09-27 1991-09-25 Substituerade 4-amino-3-pyridinoler, foerfarande foer deras framstaellning och deras anvaendning som laekemedel.

Country Status (22)

Country Link
US (3) US5821239A (fi)
EP (1) EP0477903B1 (fi)
JP (1) JP3090511B2 (fi)
KR (1) KR100215357B1 (fi)
AT (1) ATE136297T1 (fi)
AU (1) AU637720B2 (fi)
CA (1) CA2052433C (fi)
CZ (1) CZ282002B6 (fi)
DE (1) DE69118470T2 (fi)
DK (1) DK0477903T3 (fi)
ES (1) ES2085940T3 (fi)
FI (1) FI914504A (fi)
GR (1) GR3019742T3 (fi)
HU (1) HUT60247A (fi)
IE (1) IE73874B1 (fi)
IL (1) IL99581A (fi)
NO (1) NO913778L (fi)
NZ (1) NZ239935A (fi)
PT (1) PT99073B (fi)
TW (1) TW200462B (fi)
YU (1) YU158591A (fi)
ZA (1) ZA917692B (fi)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6218383B1 (en) 1998-08-07 2001-04-17 Targacept, Inc. Pharmaceutical compositions for the prevention and treatment of central nervous system disorders
FR2813891B1 (fr) * 2000-09-14 2005-01-14 Immunotech Sa Reactif multifonctionnel pour erythrocytes mettant en jeu des carbamates et applications
DE10102791B4 (de) * 2001-01-22 2004-04-15 Ifm Electronic Gmbh Elektrischer Meßumformer
US7067517B2 (en) * 2001-12-14 2006-06-27 Nero Nordisk A/S Use of compounds for decreasing activity of hormone-sensitive lipase
KR100443983B1 (ko) 2002-01-15 2004-08-09 삼성전자주식회사 냉장고
US8007826B2 (en) 2003-12-11 2011-08-30 Acorda Therapeutics, Inc. Sustained release aminopyridine composition
US8354437B2 (en) 2004-04-09 2013-01-15 Acorda Therapeutics, Inc. Method of using sustained release aminopyridine compositions
KR101063585B1 (ko) * 2005-02-17 2011-09-07 아스텔라스세이야쿠 가부시키가이샤 피리딜 비방향족 질소 함유 헤테로환-1-카르복실산에스테르 유도체
WO2010030755A1 (en) * 2008-09-10 2010-03-18 Acorda Therapeutics, Inc. Methods of using sustained release aminopyridine compositions
EA037187B1 (ru) 2010-02-09 2021-02-17 Дзе Джонс Хопкинс Юниверсити Способ и композиция для лечения когнитивного расстройства
US10154988B2 (en) 2012-11-14 2018-12-18 The Johns Hopkins University Methods and compositions for treating schizophrenia
MX362886B (es) 2012-12-13 2019-02-22 H Lundbeck As Composición sinérgica que comprende vortioxetina y donepezilo para incrementar los niveles de acetilcolina en el cerebro, y el uso de la misma en el tratamiento de una disfunción cognitiva.
WO2014144801A1 (en) 2013-03-15 2014-09-18 Agenebio Inc. Methods and compositions for improving cognitive function
WO2014144663A1 (en) 2013-03-15 2014-09-18 The Johns Hopkins University Methods and compositions for improving cognitive function
US10925834B2 (en) 2015-05-22 2021-02-23 Agenebio, Inc. Extended release pharmaceutical compositions of levetiracetam

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4179563A (en) * 1978-05-19 1979-12-18 Warner-Lambert Company 3-Aryloxy-substituted-aminopyridines and methods for their production
US4734275A (en) * 1983-08-19 1988-03-29 Research Corporation Anti-curare agents
DE3514073A1 (de) * 1985-04-18 1986-10-23 Hoechst Ag, 6230 Frankfurt Mehrfach substituierte pyridin-1-oxide, verfahren zu ihrer herstellung, die sie enthaltenden arzneimittel und ihre verwendung
US4735958A (en) * 1986-12-22 1988-04-05 Warner-Lambert Company Trans-6-[2-[2-(substituted-phenyl)-3- (or 4-) heteroaryl-5-substituted-1H-pyrrol-1-yl]-ethyl]tetrahydro-4-hydroxy-2H-pyran-2-one inhibitors of cholesterol biosynthesis
US4831044A (en) * 1987-10-29 1989-05-16 Ici Americas Inc. Fungicidal pyridyl cyclopropane carboxamidines
US4994473A (en) * 1987-11-17 1991-02-19 Ici Americas Inc. Pyridyl containing insecticides
EP0361489A3 (en) * 1988-09-30 1991-06-12 Chugai Seiyaku Kabushiki Kaisha Novel 3,4-diaminoquinoline and pyridine compounds
ATE89553T1 (de) * 1988-11-16 1993-06-15 Hoechst Roussel Pharma Hydroxy-1,2,3,4-tetrahydroaminoacridine, verfahren fuer ihre herstellung und ihre verwendung als arzneimittel.
US4931457B1 (en) * 1989-06-28 1993-11-16 Hoechst-Roussel Pharmaceuticals Incorporated Naphthylamino-and naphthyloxy-pyridineamin compounds useful as topical antiinflammatory agents for the treatment of skin disorders

Also Published As

Publication number Publication date
IL99581A (en) 1995-07-31
ATE136297T1 (de) 1996-04-15
EP0477903B1 (en) 1996-04-03
KR920006318A (ko) 1992-04-27
YU158591A (sh) 1994-12-28
EP0477903A3 (en) 1992-08-05
ZA917692B (en) 1992-05-27
HUT60247A (en) 1992-08-28
DE69118470D1 (de) 1996-05-09
IL99581A0 (en) 1992-08-18
US5869480A (en) 1999-02-09
HU913075D0 (en) 1992-01-28
AU637720B2 (en) 1993-06-03
NO913778D0 (no) 1991-09-26
US5821239A (en) 1998-10-13
ES2085940T3 (es) 1996-06-16
KR100215357B1 (ko) 1999-08-16
CA2052433C (en) 2003-04-15
IE913389A1 (en) 1992-04-08
DK0477903T3 (da) 1996-07-29
TW200462B (fi) 1993-02-21
JP3090511B2 (ja) 2000-09-25
JPH04261157A (ja) 1992-09-17
NO913778L (no) 1992-03-30
IE73874B1 (en) 1997-07-02
PT99073B (pt) 1999-02-26
AU8475691A (en) 1992-04-02
CA2052433A1 (en) 1992-03-28
NZ239935A (en) 1995-07-26
CZ282002B6 (cs) 1997-04-16
GR3019742T3 (en) 1996-07-31
PT99073A (pt) 1992-08-31
US5866565A (en) 1999-02-02
EP0477903A2 (en) 1992-04-01
CS293691A3 (en) 1992-04-15
FI914504A (fi) 1992-03-28
DE69118470T2 (de) 1996-09-19

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Legal Events

Date Code Title Description
FD Application lapsed