DK0477903T3 - Substituerede 4-amino-3-pyridinoler, fremgangsmåde til deres fremstilling og deres anvendelse som lægemidler - Google Patents
Substituerede 4-amino-3-pyridinoler, fremgangsmåde til deres fremstilling og deres anvendelse som lægemidlerInfo
- Publication number
- DK0477903T3 DK0477903T3 DK91116336.8T DK91116336T DK0477903T3 DK 0477903 T3 DK0477903 T3 DK 0477903T3 DK 91116336 T DK91116336 T DK 91116336T DK 0477903 T3 DK0477903 T3 DK 0477903T3
- Authority
- DK
- Denmark
- Prior art keywords
- loweralkyl
- chem
- hydrogen
- preparation
- pyridinols
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/26—Radicals substituted by halogen atoms or nitro radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Surface Treatment Of Glass (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US58911390A | 1990-09-27 | 1990-09-27 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0477903T3 true DK0477903T3 (da) | 1996-07-29 |
Family
ID=24356648
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK91116336.8T DK0477903T3 (da) | 1990-09-27 | 1991-09-25 | Substituerede 4-amino-3-pyridinoler, fremgangsmåde til deres fremstilling og deres anvendelse som lægemidler |
Country Status (22)
| Country | Link |
|---|---|
| US (3) | US5821239A (da) |
| EP (1) | EP0477903B1 (da) |
| JP (1) | JP3090511B2 (da) |
| KR (1) | KR100215357B1 (da) |
| AT (1) | ATE136297T1 (da) |
| AU (1) | AU637720B2 (da) |
| CA (1) | CA2052433C (da) |
| CZ (1) | CZ282002B6 (da) |
| DE (1) | DE69118470T2 (da) |
| DK (1) | DK0477903T3 (da) |
| ES (1) | ES2085940T3 (da) |
| FI (1) | FI914504A (da) |
| GR (1) | GR3019742T3 (da) |
| HU (1) | HUT60247A (da) |
| IE (1) | IE73874B1 (da) |
| IL (1) | IL99581A (da) |
| NO (1) | NO913778L (da) |
| NZ (1) | NZ239935A (da) |
| PT (1) | PT99073B (da) |
| TW (1) | TW200462B (da) |
| YU (1) | YU158591A (da) |
| ZA (1) | ZA917692B (da) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6218383B1 (en) | 1998-08-07 | 2001-04-17 | Targacept, Inc. | Pharmaceutical compositions for the prevention and treatment of central nervous system disorders |
| FR2813891B1 (fr) * | 2000-09-14 | 2005-01-14 | Immunotech Sa | Reactif multifonctionnel pour erythrocytes mettant en jeu des carbamates et applications |
| DE10102791B4 (de) * | 2001-01-22 | 2004-04-15 | Ifm Electronic Gmbh | Elektrischer Meßumformer |
| AU2002351731A1 (en) * | 2001-12-14 | 2003-06-30 | Novo Nordisk A/S | Compounds and uses thereof for decreasing activity of hormone-sensitive lipase |
| KR100443983B1 (ko) | 2002-01-15 | 2004-08-09 | 삼성전자주식회사 | 냉장고 |
| US8007826B2 (en) | 2003-12-11 | 2011-08-30 | Acorda Therapeutics, Inc. | Sustained release aminopyridine composition |
| US8354437B2 (en) | 2004-04-09 | 2013-01-15 | Acorda Therapeutics, Inc. | Method of using sustained release aminopyridine compositions |
| ES2528674T3 (es) | 2005-02-17 | 2015-02-11 | Astellas Pharma Inc. | Piperidina y carboxilatos de piperacina como inhibidores de FAAH |
| US20100061935A1 (en) * | 2008-09-10 | 2010-03-11 | Acorda Therapeutics, Inc. | Methods of using sustained release aminopyridine compositions |
| EP2533645B1 (en) | 2010-02-09 | 2016-07-27 | The Johns Hopkins University | Methods and compositions for improving cognitive function |
| EP2919788A4 (en) | 2012-11-14 | 2016-05-25 | Univ Johns Hopkins | METHODS AND COMPOSITIONS FOR THE TREATMENT OF SCHIZOPHRENIA |
| MX362886B (es) | 2012-12-13 | 2019-02-22 | H Lundbeck As | Composición sinérgica que comprende vortioxetina y donepezilo para incrementar los niveles de acetilcolina en el cerebro, y el uso de la misma en el tratamiento de una disfunción cognitiva. |
| DK2968220T3 (da) | 2013-03-15 | 2021-06-14 | Agenebio Inc | Fremgangsmåder og sammensætninger til forbedring af kognitiv funktion |
| EP2968237A4 (en) | 2013-03-15 | 2016-08-31 | Univ Johns Hopkins | METHOD AND COMPOSITIONS FOR IMPROVING COGNITIVE FUNCTION |
| BR112017025031B1 (pt) | 2015-05-22 | 2023-03-21 | Agenebio, Inc | Composições farmacêuticas de liberação prolongada de levetiracetam |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4179563A (en) * | 1978-05-19 | 1979-12-18 | Warner-Lambert Company | 3-Aryloxy-substituted-aminopyridines and methods for their production |
| US4734275A (en) * | 1983-08-19 | 1988-03-29 | Research Corporation | Anti-curare agents |
| DE3514073A1 (de) * | 1985-04-18 | 1986-10-23 | Hoechst Ag, 6230 Frankfurt | Mehrfach substituierte pyridin-1-oxide, verfahren zu ihrer herstellung, die sie enthaltenden arzneimittel und ihre verwendung |
| US4735958A (en) * | 1986-12-22 | 1988-04-05 | Warner-Lambert Company | Trans-6-[2-[2-(substituted-phenyl)-3- (or 4-) heteroaryl-5-substituted-1H-pyrrol-1-yl]-ethyl]tetrahydro-4-hydroxy-2H-pyran-2-one inhibitors of cholesterol biosynthesis |
| US4831044A (en) * | 1987-10-29 | 1989-05-16 | Ici Americas Inc. | Fungicidal pyridyl cyclopropane carboxamidines |
| US4994473A (en) * | 1987-11-17 | 1991-02-19 | Ici Americas Inc. | Pyridyl containing insecticides |
| EP0361489A3 (en) * | 1988-09-30 | 1991-06-12 | Chugai Seiyaku Kabushiki Kaisha | Novel 3,4-diaminoquinoline and pyridine compounds |
| NZ231376A (en) * | 1988-11-16 | 1992-05-26 | Hoechst Roussel Pharma | Hydroxy-1,2,3,4-tetrahydroaminoacridine derivatives, preparation and pharmaceutical compositions thereof |
| US4931457B1 (en) * | 1989-06-28 | 1993-11-16 | Hoechst-Roussel Pharmaceuticals Incorporated | Naphthylamino-and naphthyloxy-pyridineamin compounds useful as topical antiinflammatory agents for the treatment of skin disorders |
-
1991
- 1991-08-31 TW TW080106907A patent/TW200462B/zh active
- 1991-09-25 EP EP91116336A patent/EP0477903B1/en not_active Expired - Lifetime
- 1991-09-25 CZ CS912936A patent/CZ282002B6/cs not_active IP Right Cessation
- 1991-09-25 DK DK91116336.8T patent/DK0477903T3/da active
- 1991-09-25 NZ NZ239935A patent/NZ239935A/en unknown
- 1991-09-25 DE DE69118470T patent/DE69118470T2/de not_active Expired - Fee Related
- 1991-09-25 AT AT91116336T patent/ATE136297T1/de not_active IP Right Cessation
- 1991-09-25 FI FI914504A patent/FI914504A/fi not_active Application Discontinuation
- 1991-09-25 ES ES91116336T patent/ES2085940T3/es not_active Expired - Lifetime
- 1991-09-26 HU HU913075A patent/HUT60247A/hu unknown
- 1991-09-26 PT PT99073A patent/PT99073B/pt not_active IP Right Cessation
- 1991-09-26 CA CA002052433A patent/CA2052433C/en not_active Expired - Fee Related
- 1991-09-26 IL IL9958191A patent/IL99581A/en not_active IP Right Cessation
- 1991-09-26 ZA ZA917692A patent/ZA917692B/xx unknown
- 1991-09-26 NO NO91913778A patent/NO913778L/no unknown
- 1991-09-26 YU YU158591A patent/YU158591A/sh unknown
- 1991-09-26 IE IE338991A patent/IE73874B1/en not_active IP Right Cessation
- 1991-09-26 AU AU84756/91A patent/AU637720B2/en not_active Expired - Fee Related
- 1991-09-26 JP JP03273439A patent/JP3090511B2/ja not_active Expired - Fee Related
- 1991-09-27 KR KR1019910016850A patent/KR100215357B1/ko not_active IP Right Cessation
-
1996
- 1996-02-16 US US08/602,693 patent/US5821239A/en not_active Expired - Fee Related
- 1996-04-24 GR GR960401135T patent/GR3019742T3/el unknown
-
1998
- 1998-06-02 US US09/088,928 patent/US5869480A/en not_active Expired - Fee Related
- 1998-06-02 US US09/088,926 patent/US5866565A/en not_active Expired - Fee Related
Also Published As
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