ES8600196A1 - Un procedimiento para preparar derivados de biciclooctano - Google Patents
Un procedimiento para preparar derivados de biciclooctanoInfo
- Publication number
- ES8600196A1 ES8600196A1 ES529281A ES529281A ES8600196A1 ES 8600196 A1 ES8600196 A1 ES 8600196A1 ES 529281 A ES529281 A ES 529281A ES 529281 A ES529281 A ES 529281A ES 8600196 A1 ES8600196 A1 ES 8600196A1
- Authority
- ES
- Spain
- Prior art keywords
- group
- hydrogen atom
- alkyl group
- image
- alkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- NLUNLVTVUDIHFE-UHFFFAOYSA-N cyclooctylcyclooctane Chemical class C1CCCCCCC1C1CCCCCCC1 NLUNLVTVUDIHFE-UHFFFAOYSA-N 0.000 title 1
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 7
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 7
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 6
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 4
- 125000005843 halogen group Chemical group 0.000 abstract 3
- 125000000623 heterocyclic group Chemical group 0.000 abstract 3
- 125000004400 (C1-C12) alkyl group Chemical group 0.000 abstract 2
- 125000006376 (C3-C10) cycloalkyl group Chemical group 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 125000000392 cycloalkenyl group Chemical group 0.000 abstract 2
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 2
- 125000004642 (C1-C12) alkoxy group Chemical group 0.000 abstract 1
- 125000000229 (C1-C4)alkoxy group Chemical group 0.000 abstract 1
- 125000006710 (C2-C12) alkenyl group Chemical group 0.000 abstract 1
- 125000006711 (C2-C12) alkynyl group Chemical group 0.000 abstract 1
- 208000007536 Thrombosis Diseases 0.000 abstract 1
- 208000025865 Ulcer Diseases 0.000 abstract 1
- 125000002947 alkylene group Chemical group 0.000 abstract 1
- 230000002785 anti-thrombosis Effects 0.000 abstract 1
- 230000000767 anti-ulcer Effects 0.000 abstract 1
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 125000004465 cycloalkenyloxy group Chemical group 0.000 abstract 1
- 125000000000 cycloalkoxy group Chemical group 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- 231100000252 nontoxic Toxicity 0.000 abstract 1
- 230000003000 nontoxic effect Effects 0.000 abstract 1
- 125000000951 phenoxy group Chemical group [H]C1=C([H])C([H])=C(O*)C([H])=C1[H] 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 231100000397 ulcer Toxicity 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
- C07C405/005—Analogues or derivatives having the five membered ring replaced by other rings
- C07C405/0075—Analogues or derivatives having the five membered ring replaced by other rings having the side-chains or their analogues or derivatives attached to a condensed ring system
- C07C405/0083—Analogues or derivatives having the five membered ring replaced by other rings having the side-chains or their analogues or derivatives attached to a condensed ring system which is only ortho or peri condensed, e.g. carbacyclins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C33/00—Unsaturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
- C07C33/05—Alcohols containing rings other than six-membered aromatic rings
- C07C33/14—Alcohols containing rings other than six-membered aromatic rings containing six-membered rings
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrane Compounds (AREA)
Abstract
/Q/BBBRJBCBBBFW
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP58015837A JPS59141536A (ja) | 1983-02-01 | 1983-02-01 | 新規ビシクロオクタン誘導体 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES8600196A1 true ES8600196A1 (es) | 1985-10-01 |
| ES529281A0 ES529281A0 (es) | 1985-10-01 |
Family
ID=11899945
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES529281A Granted ES529281A0 (es) | 1983-02-01 | 1984-01-30 | Un procedimiento para preparar derivados de biciclooctano |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US4680307A (es) |
| EP (1) | EP0115954B1 (es) |
| JP (1) | JPS59141536A (es) |
| AT (1) | ATE29024T1 (es) |
| AU (1) | AU567911B2 (es) |
| CA (1) | CA1252461A (es) |
| DE (1) | DE3465470D1 (es) |
| DK (1) | DK171295B1 (es) |
| ES (1) | ES529281A0 (es) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3428266A1 (de) * | 1984-07-27 | 1986-01-30 | Schering AG, 1000 Berlin und 4709 Bergkamen | Neue carbacycline, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel |
| US5523321A (en) * | 1985-07-19 | 1996-06-04 | Schering Aktiengeselleschaft | Prostacyclins, their analogs or prostaglandins and thromboxane antagonists for treatment of thrombotic and thromboembolic syndromes |
| JPS62153259A (ja) * | 1985-12-26 | 1987-07-08 | Sagami Chem Res Center | （２−クロロ−３−オキソ−１−アルケニル）−ビシクロ〔３．３．０〕オクテン誘導体及びその製法 |
| DE3608088C2 (de) * | 1986-03-07 | 1995-11-16 | Schering Ag | Pharmazeutische Präparate, enthaltend Cyclodextrinclathrate von Carbacyclinderivaten |
| GB2192395B (en) * | 1986-07-08 | 1990-11-14 | Kotobuki Seiyaku Co Ltd | Carbacyclin derivatives |
| JPH01110644A (ja) * | 1986-12-04 | 1989-04-27 | Sagami Chem Res Center | ホモイソカルバサイクリン類縁体並びにそれを有効成分とする循環改善剤及び抗潰瘍剤 |
| ATE306256T1 (de) | 1999-08-05 | 2005-10-15 | Teijin Ltd | Mittel zur besserung der neuropathie, die als wirkstoff stickstoffhaltige verbindungen enthalten |
| ES2525748T3 (es) | 2009-11-13 | 2014-12-29 | Toray Industries, Inc. | Agente terapéutico o profiláctico para la diabetes |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3923861A (en) * | 1969-07-29 | 1975-12-02 | Upjohn Co | 3-Oxa prostaglandin F{331 -type compounds |
| JPS5495552A (en) * | 1978-01-06 | 1979-07-28 | Sankyo Co Ltd | Prostacyline derivative and its preparation |
| DE2912409A1 (de) * | 1978-03-31 | 1979-10-11 | Ono Pharmaceutical Co | 6,9-methano-pgi tief 2 -analoge |
| DE3168001D1 (en) * | 1980-03-21 | 1985-02-14 | Sumitomo Chemical Co | Bicyclooctane derivatives, processes for producing them, pharmaceutical compositions containing them, their use as pharmaceuticals and precursors thereof |
| DE3048906A1 (de) * | 1980-12-19 | 1982-07-15 | Schering Ag, 1000 Berlin Und 4619 Bergkamen | Neue carbacycline, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel |
| DE3104044A1 (de) * | 1981-02-02 | 1982-08-26 | Schering Ag, 1000 Berlin Und 4619 Bergkamen | Neue prostacyclin-derivate, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel |
| JPS58110539A (ja) * | 1981-12-25 | 1983-07-01 | Sankyo Co Ltd | カルバプロスタサイクリン類 |
| GR77976B (es) * | 1982-03-12 | 1984-09-25 | Schering Ag | |
| DE3225288A1 (de) * | 1982-07-02 | 1984-01-19 | Schering AG, 1000 Berlin und 4709 Bergkamen | Neue carbacycline, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel |
| DE3226550A1 (de) * | 1982-07-13 | 1984-01-19 | Schering AG, 1000 Berlin und 4709 Bergkamen | Neue carbacycline, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel |
| JPS5913747A (ja) * | 1982-07-14 | 1984-01-24 | Ota Seiyaku Kk | シス−ビシクロ〔３，３，０〕オクタン化合物及びその製造法 |
| JPS5916852A (ja) * | 1982-07-19 | 1984-01-28 | Ota Seiyaku Kk | シス−ビシクロ〔３，３，０〕オクタン化合物 |
-
1983
- 1983-02-01 JP JP58015837A patent/JPS59141536A/ja active Granted
-
1984
- 1984-01-24 AU AU23726/84A patent/AU567911B2/en not_active Ceased
- 1984-01-25 CA CA000446010A patent/CA1252461A/en not_active Expired
- 1984-01-26 US US06/574,125 patent/US4680307A/en not_active Expired - Lifetime
- 1984-01-30 ES ES529281A patent/ES529281A0/es active Granted
- 1984-01-31 AT AT84300597T patent/ATE29024T1/de not_active IP Right Cessation
- 1984-01-31 EP EP84300597A patent/EP0115954B1/en not_active Expired
- 1984-01-31 DE DE8484300597T patent/DE3465470D1/de not_active Expired
- 1984-01-31 DK DK043384A patent/DK171295B1/da not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| JPH0414091B2 (es) | 1992-03-11 |
| DK43384D0 (da) | 1984-01-31 |
| ATE29024T1 (de) | 1987-09-15 |
| DK43384A (da) | 1984-08-02 |
| US4680307A (en) | 1987-07-14 |
| EP0115954A3 (en) | 1984-11-07 |
| DK171295B1 (da) | 1996-08-26 |
| AU2372684A (en) | 1984-08-02 |
| EP0115954A2 (en) | 1984-08-15 |
| EP0115954B1 (en) | 1987-08-19 |
| DE3465470D1 (en) | 1987-09-24 |
| CA1252461A (en) | 1989-04-11 |
| JPS59141536A (ja) | 1984-08-14 |
| ES529281A0 (es) | 1985-10-01 |
| AU567911B2 (en) | 1987-12-10 |
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