YU140991A - 3-(1,2-benzizoksazol-3-il)-4-piridinamini i derivati - Google Patents

3-(1,2-benzizoksazol-3-il)-4-piridinamini i derivati

Info

Publication number
YU140991A
YU140991A YU140991A YU140991A YU140991A YU 140991 A YU140991 A YU 140991A YU 140991 A YU140991 A YU 140991A YU 140991 A YU140991 A YU 140991A YU 140991 A YU140991 A YU 140991A
Authority
YU
Yugoslavia
Prior art keywords
hydrogen
derivatives
pyridinamines
benzisoxazol
loweralkyl
Prior art date
Application number
YU140991A
Other languages
English (en)
Inventor
Y.T. Klein
R. Ch. Effland
Original Assignee
Hoechst-Roussel Pharmaceuticals Incorporated
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst-Roussel Pharmaceuticals Incorporated filed Critical Hoechst-Roussel Pharmaceuticals Incorporated
Publication of YU140991A publication Critical patent/YU140991A/sh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Rheumatology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

3-(1,2-BENZIZOKSAZOL-3-IL)-4-PIRIDINAMINI I DERIVATI, predloženi pronalazak se odnosi na 3-(1,2-benzizok-sazol-3-il)-4 piridinamine formule: u kojoj je R1 vodonik, nižialkil, arilalkil ili acil; R2 vodonik, nižialkil ili arilalkil; X vodonik, halogen, nitro ili amino njihove farmaceutski prihvatljive adicione soli, geometrijske i optičke izomere kao i njihove racemske smeše. Jedinjenja prema pronalasku su korisna kao analgetici; za regulisanje disfunkcije pamćenja, koju karakteriše pomanjkanje antiholinergina; zatim kao stimulatori kod lečenja senilnosti kao što je Alzheimerijeva bolest i za lokalno lečenje raznih dermatoza.
YU140991A 1990-08-13 1991-08-14 3-(1,2-benzizoksazol-3-il)-4-piridinamini i derivati YU140991A (sh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/566,932 US5055476A (en) 1990-08-13 1990-08-13 3-(1,2-benzisoxazol-3-yl)-4-pyridinamines and derivatives

Publications (1)

Publication Number Publication Date
YU140991A true YU140991A (sh) 1995-01-31

Family

ID=24265033

Family Applications (1)

Application Number Title Priority Date Filing Date
YU140991A YU140991A (sh) 1990-08-13 1991-08-14 3-(1,2-benzizoksazol-3-il)-4-piridinamini i derivati

Country Status (24)

Country Link
US (1) US5055476A (sh)
EP (1) EP0471297B1 (sh)
JP (1) JP3057829B2 (sh)
KR (1) KR100191386B1 (sh)
AT (1) ATE130004T1 (sh)
AU (1) AU633791B2 (sh)
CA (1) CA2048959C (sh)
CZ (1) CZ280568B6 (sh)
DE (1) DE69114405T2 (sh)
DK (1) DK0471297T3 (sh)
ES (1) ES2079531T3 (sh)
FI (1) FI103970B (sh)
GR (1) GR3018184T3 (sh)
HU (1) HU213201B (sh)
IE (1) IE70597B1 (sh)
IL (1) IL99166A (sh)
MX (1) MX9100639A (sh)
NO (1) NO179519C (sh)
NZ (1) NZ239326A (sh)
PT (1) PT98645B (sh)
RU (1) RU2012561C1 (sh)
TW (1) TW202446B (sh)
YU (1) YU140991A (sh)
ZA (1) ZA916342B (sh)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5308826A (en) * 1993-04-22 1994-05-03 Zeneca Limited Herbicidal 4-substituted pyridyl-3-carbinols
US5595958A (en) * 1994-05-02 1997-01-21 Zeneca Limited 3-substituted pyridine compounds and derivatives thereof
AU2313995A (en) * 1994-05-02 1995-11-29 Zeneca Limited Herbicidal hydroxybenzyl-substituted heteroaryl compounds and derivatives thereof
DK2718270T3 (da) 2011-06-10 2022-08-01 Merck Patent Gmbh Sammensætninger og fremgangsmåder til fremstillingen af pyrimidin- og pyridinforbindelser med btk-hæmmende aktivitet
RU2626650C2 (ru) * 2015-08-31 2017-07-31 Федеральное государственное бюджетное образовательное учреждение высшего образования "Пермский государственный национальный исследовательский университет" 2-Арил-2,4-дигидрокси-2,5-дигидро-3-гетерил-5-оксо-1Н-пиррол-1-ил-4-метилбелзолсульфаниламиды, обладающие анальгетической активностью
WO2023083445A1 (en) 2021-11-10 2023-05-19 Symrise Ag Compositions comprising trpm8 agonistic cooling agents

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4355037A (en) * 1981-11-12 1982-10-19 Hoechst-Roussel Pharmaceuticals 3-(4-Piperidyl)-1,2-benzisoxales
IL66866A (en) * 1982-04-09 1987-08-31 Hoechst Roussel Pharma 1-(3-(6-fluoro-1,2-benzisoxazol-3-yl)propyl)-4-(substituted)-piperazines and-piperidines,a process for the preparation thereof,and pharmaceutical compositions containing them
CA1335289C (en) * 1987-10-26 1995-04-18 Fujio Antoku Piperidinyl benzisoxazole derivatives, their production and pharmaceutical use
IE74711B1 (en) * 1990-07-27 1997-07-30 Ici Plc Fungicides

Also Published As

Publication number Publication date
NO913142L (no) 1992-02-14
FI103970B1 (fi) 1999-10-29
PT98645B (pt) 1999-01-29
IL99166A (en) 1995-12-08
EP0471297A1 (en) 1992-02-19
CZ280568B6 (cs) 1996-02-14
MX9100639A (es) 1992-04-01
GR3018184T3 (en) 1996-02-29
NO913142D0 (no) 1991-08-12
JPH05112562A (ja) 1993-05-07
NO179519C (no) 1996-10-23
JP3057829B2 (ja) 2000-07-04
EP0471297B1 (en) 1995-11-08
DE69114405T2 (de) 1996-05-02
HU213201B (en) 1997-03-28
CS248991A3 (en) 1992-03-18
US5055476A (en) 1991-10-08
IE912851A1 (en) 1992-02-26
IL99166A0 (en) 1992-07-15
ES2079531T3 (es) 1996-01-16
DK0471297T3 (da) 1996-03-04
RU2012561C1 (ru) 1994-05-15
TW202446B (sh) 1993-03-21
NZ239326A (en) 1994-04-27
FI913800A0 (fi) 1991-08-09
IE70597B1 (en) 1996-12-11
PT98645A (pt) 1992-06-30
CA2048959C (en) 2003-07-29
AU8176591A (en) 1992-02-20
ZA916342B (en) 1992-04-29
DE69114405D1 (de) 1995-12-14
ATE130004T1 (de) 1995-11-15
KR100191386B1 (ko) 1999-06-15
CA2048959A1 (en) 1992-02-14
NO179519B (no) 1996-07-15
KR920004383A (ko) 1992-03-27
HU912673D0 (en) 1992-01-28
FI913800A (fi) 1992-02-14
HUT61755A (en) 1993-03-01
AU633791B2 (en) 1993-02-04
FI103970B (fi) 1999-10-29

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