WO2020082039A1 - Adjustable medical device - Google Patents

Adjustable medical device Download PDF

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Publication number
WO2020082039A1
WO2020082039A1 PCT/US2019/057082 US2019057082W WO2020082039A1 WO 2020082039 A1 WO2020082039 A1 WO 2020082039A1 US 2019057082 W US2019057082 W US 2019057082W WO 2020082039 A1 WO2020082039 A1 WO 2020082039A1
Authority
WO
WIPO (PCT)
Prior art keywords
medical device
configuration
shuttle
elongate body
shape
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2019/057082
Other languages
English (en)
French (fr)
Inventor
Claudio Argento
Andrew Backus
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Shifamed Holdings LLC
Original Assignee
Shifamed Holdings LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shifamed Holdings LLC filed Critical Shifamed Holdings LLC
Priority to EP25223071.9A priority Critical patent/EP4721804A2/en
Priority to CN201980076303.2A priority patent/CN113056302B/zh
Priority to US17/286,724 priority patent/US12403008B2/en
Priority to JP2021521239A priority patent/JP7489975B2/ja
Priority to EP19874300.7A priority patent/EP3866900B1/en
Priority to AU2019362078A priority patent/AU2019362078B2/en
Priority to CA3115714A priority patent/CA3115714A1/en
Publication of WO2020082039A1 publication Critical patent/WO2020082039A1/en
Anticipated expiration legal-status Critical
Priority to JP2024078328A priority patent/JP7821839B2/ja
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/00064—Constructional details of the endoscope body
    • A61B1/00071—Insertion part of the endoscope body
    • A61B1/00078—Insertion part of the endoscope body with stiffening means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/005—Flexible endoscopes
    • A61B1/0051—Flexible endoscopes with controlled bending of insertion part
    • A61B1/0055—Constructional details of insertion parts, e.g. vertebral elements
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A61B18/14—Probes or electrodes therefor
    • A61B18/1492—Probes or electrodes therefor having a flexible, catheter-like structure, e.g. for heart ablation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/24—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
    • A61F2/2442—Annuloplasty rings or inserts for correcting the valve shape; Implants for improving the function of a native heart valve
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/24—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
    • A61F2/2442—Annuloplasty rings or inserts for correcting the valve shape; Implants for improving the function of a native heart valve
    • A61F2/2466—Delivery devices therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/01—Introducing, guiding, advancing, emplacing or holding catheters
    • A61M25/09—Guide wires
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/005—Flexible endoscopes
    • A61B1/0058—Flexible endoscopes using shape-memory elements
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/00234—Surgical instruments, devices or methods for minimally invasive surgery
    • A61B2017/00292—Surgical instruments, devices or methods for minimally invasive surgery mounted on or guided by flexible, e.g. catheter-like, means
    • A61B2017/003—Steerable
    • A61B2017/00305—Constructional details of the flexible means
    • A61B2017/00309—Cut-outs or slits
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B2017/00831—Material properties
    • A61B2017/00867—Material properties shape memory effect
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00315—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for treatment of particular body parts
    • A61B2018/00345—Vascular system
    • A61B2018/00351—Heart
    • A61B2018/00357—Endocardium
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00571—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for achieving a particular surgical effect
    • A61B2018/00577—Ablation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A61B18/14—Probes or electrodes therefor
    • A61B2018/1467—Probes or electrodes therefor using more than two electrodes on a single probe
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/24—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
    • A61F2/2442—Annuloplasty rings or inserts for correcting the valve shape; Implants for improving the function of a native heart valve
    • A61F2/2454—Means for preventing inversion of the valve leaflets, e.g. chordae tendineae prostheses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2220/00—Fixations or connections for prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2220/0008—Fixation appliances for connecting prostheses to the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2230/00—Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2230/0063—Three-dimensional shapes
    • A61F2230/0091—Three-dimensional shapes helically-coiled or spirally-coiled, i.e. having a 2-D spiral cross-section
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2250/00—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2250/0014—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof having different values of a given property or geometrical feature, e.g. mechanical property or material property, at different locations within the same prosthesis
    • A61F2250/0029—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof having different values of a given property or geometrical feature, e.g. mechanical property or material property, at different locations within the same prosthesis differing in bending or flexure capacity
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/01—Introducing, guiding, advancing, emplacing or holding catheters
    • A61M25/09—Guide wires
    • A61M2025/09133—Guide wires having specific material compositions or coatings; Materials with specific mechanical behaviours, e.g. stiffness, strength to transmit torque
    • A61M2025/09141—Guide wires having specific material compositions or coatings; Materials with specific mechanical behaviours, e.g. stiffness, strength to transmit torque made of shape memory alloys which take a particular shape at a certain temperature

Definitions

  • Shape-memory devices are commonly used for minimally-invasive medical procedures due to their ability to return to a desired configuration upon release from a delivery device (in which the shape-memory devices are typically constrained in a narrower profile delivery configuration).
  • many shape-memory devices require specialized delivery devices and methods to maintain the devices in a delivery configuration which enables minimally-invasive delivery to a target tissue, which may be less than ideal.
  • shape-memory devices may not be sufficiently strong enough to be applied in certain medical procedures which may otherwise be accessible for minimally-invasive techniques.
  • the present disclosure generally relates to medical devices and more particularly to elongate medical devices capable of being transitioned from a smaller profile delivery configuration to larger profile delivered configuration.
  • a medical device comprising an elongate body having a first configuration and a second configuration, the second configuration having a different shape from the first configuration; shape changing features on the elongate body configured to allow the elongate body to change shape from the first configuration to the second configuration; and a locking mechanism configured to lock the elongate body in the second configuration.
  • a medical device in another aspect, comprises an elongate body; a spine portion extending along a sidewall of the elongate body; a plurality of openings extending from the spine portion; a shuttle axially movable along the elongate body; a tension member connecting a connection point positioned distally of the shuttle and the shuttle; a pull member extending proximally from the shuttle; and a locking mechanism configured to hold the shuttle in a proximally pulled position, wherein the medical device comprises a relaxed configuration before the shuttle is pulled proximally and a stiffened configuration after the shuttle is pulled proximally, the stiffened configuration causing the medical device to assume a predetermined, curved configuration, and wherein the plurality of openings is configured to have a first shape in the relaxed configuration and a second shape, different from the first shape in the stiffened configuration.
  • a width of the openings changes between the first shape and the second shape.
  • the radius of curvature of the predetermined, curved configuration can be determined by a width of the openings.
  • the plurality of openings comprises openings of varying size.
  • the spine portion can curve around at least a portion of the elongate body.
  • the spine portion is arranged in a helical pattern around the elongate body.
  • a pitch or coil angle alpha of the predetermined, curved configuration can be determined by a pitch or coil angle of the spine portion.
  • the spine can be straight and the slots angled relative to the spine.
  • the device can comprise a second connection point proximal to the connection point and a second wire connecting the second connection point to a second shuttle positioned proximally to the second connection point.
  • the device comprises a plurality of shuttles and a plurality of locking mechanisms.
  • the locking mechanism comprises a pin attached to the shuttle positioned in and configured to slide along a track extending along a length of the elongate body. The track can twist as it extends proximally, forming a locking area for the pin.
  • the elongate body further comprises a release window configured to allow disengagement of the pull member from the shuttle. The device can be configured to expose the pull member to the release window when the pin is moved to the locking area.
  • the locking mechanism comprises a flexible screw positioned proximally to the shuttle, the flexible screw configured to be screwed to the shuttle or a component attached to the shuttle.
  • the flexible screw can be configured to be screwed to a spring attached to the shuttle.
  • the flexible screw is configured to be screwed to a clip attached to the shuttle.
  • the device can be configured to be delivered by a catheter.
  • a center portion of the device is configured to allow passage of a guidewire therethrough.
  • the device can comprise a catheter through which the medical device can be inserted.
  • the device is configured to be connected to an end of a catheter.
  • a method of deploying a medical device comprises advancing an elongate medical device to a target area in a patient’s body, the medical device comprising a plurality of openings extending from a spine portion of a wall of the anchor, the medical device advanced in a first slack configuration; moving the medical device into a stiffened configuration by pulling proximally on a shuttle movable along the medical device, causing a tension member connecting the shuttle to a distal connection point to pull the distal connection point proximally; and locking the medical device in the stiff, activated configuration, the activated configuration comprising a predetermined curved shape.
  • the method comprising activating the anchor comprises pulling proximally on a pull member attached to the shuttle while maintaining the position of the proximal end of the anchor.
  • Locking the anchor can comprise moving a pin into a stop position along a track.
  • locking the anchor comprises screwing a screw to a component attached to the shuttle.
  • the target area comprises a native valve in a heart in the patient’s body.
  • the method further comprises advancing the elongate medical device from a first side of the native valve to a second side of the native valve.
  • the method further comprises capturing one or more structures on the second side of the native valve with the elongate medical device in the first slack
  • the native valve comprises a mitral valve
  • the first side comprises a left atrium
  • the second side comprises a left ventricle
  • the one or more structures comprise one or more chordae tendineae or native leaflets.
  • the method further comprises, after moving the medical device into the stiffened configuration, expanding at least a portion of an expandable valve prosthesis within at least a portion the elongate medical device adjacent the native valve, thereby anchoring the valve prosthesis to the native valve. Expanding the valve prosthesis can capture one or more structures of the native valve between the valve prosthesis and the elongate medical device.
  • the native valve comprises a mitral valve
  • the first side comprises a left atrium
  • the second side comprises a left ventricle
  • the one or more structures comprise one or more chordae tendineae or native leaflets.
  • a method of advancing a medical device to a target area comprises advancing an elongate body towards the target area and out of a distal end of a delivery catheter, the elongate body comprising a first curved shape as the elongate body is advanced towards the target area; locking at least a portion of the elongate body into the first curved shape; moving the elongate body into a second curved shape at or near the target area, the second curved shape different from the first curved shape; and locking the elongate body into the second curved shape.
  • a distal portion of the device can be curved during navigation from a distal end of a delivery catheter to the target area.
  • a larger or different portion of the device can be locked into a desired final shape.
  • the elongate body is delivered out of the delivery catheter such that it follows the shape of the delivery catheter and then upon delivery to the target area the elongate body is locked into its delivery curved shape.
  • an anchor for use in transcatheter mitral valve repair comprises an elongate body; a spine portion along a sidewall of the elongate body; a plurality of openings extending from the spine portion; a connection point fixed to the elongate body; a shuttle positioned proximally to the connection point and axially movable along the elongate body; a wire connecting the connection point and the shuttle; a pull member extending proximally from the shuttle; and a locking mechanism for holding the shuttle in a proximally pulled position, the proximally pulled position causing the anchor to assume a predetermined, curved configuration.
  • the spine portion is arranged to traverse a helical path around the elongate body.
  • the slots are angled relative to the spine.
  • the anchor can comprise a second connection point proximal to the connection point and a second wire connecting the second connection point to a second shuttle positioned proximally to the second connection point.
  • a method of performing transcatheter mitral valve repair comprises advancing a guidewire or guide catheter through an opening in the atrial septum, across a location near the anteromedial commissure; advancing an elongate anchor comprising a plurality of openings extending from a spine portion of a sidewall of the anchor over the guidewire such that the anchor forms at least one coil around the chordae and one coil in the left atrium, the anchor advanced in a first slack configuration; activating the anchor into a stiffened configuration having a predetermined curved shape by pulling proximally on a shuttle movable along the anchor, causing a wire connecting the shuttle to a distal connection point to pull the distal connection point proximally; and locking the anchor in the stiffened configuration.
  • the anchor is delivered around the chordae and/or the leaflets. In the stiffened configuration, the anchor can be tightened around the chordae and/or the leaflets.
  • a device for performing non-occlusive ablation comprises an elongate body; one or more electrodes positioned along the elongate body; a spine portion along a sidewall of the elongate body; a plurality of openings extending from the spine portion; a connection point fixed to the elongate body; a shuttle positioned proximally to the connection point and axially movable along the elongate body; a tension member connecting the connection point and the shuttle; a pull member extending proximally from the shuttle; and a locking mechanism for holding the shuttle in a proximally pulled position, the proximally pulled position causing the device to assume a predetermined, curved configuration.
  • a method for performing non occlusive ablation comprises advancing an elongate ablation device comprising a plurality of openings extending from a spine portion of a sidewall of the ablation device through the vasculature to a target site to be ablated, the ablation device advanced in a first slack configuration; moving the device into a stiffened configuration having a predetermined, curved shape by pulling proximally on a shuttle movable along the device, causing a wire connecting the shuttle to a distal connection point to pull the distal connection point proximally; and energizing one or more electrodes positioned along the device to ablate tissue near the device.
  • the spine portion is in the outer most position when the device is in a stiffened configuration.
  • the spine portion can comprise electrodes.
  • the entire spine portion can comprise a metal and act as the electrode.
  • the method comprises locking the device into a stiffened configuration.
  • the method can comprise positioning the device against a tissue site to be ablated.
  • locking the ablation device causes the one or more electrodes to be in contact with the target site.
  • FIGS. 1A and 1B show side and top views, respectively, of an adjustable medical device having undeployed and deployed configurations, according to embodiments of the present disclosure.
  • FIGS. 1C, 1D, and 1E show side and perspective views of an adjustable medical device in a relaxed and in a stiffened configuration, according to embodiments of the present disclosure.
  • FIGS. 2A and 2B illustrate perspective and section views, respectively, of a locking mechanism on an adjustable medical device, according to embodiments of the present disclosure.
  • FIGS. 3A-3F show magnified side views of a locking and release mechanism on an adjustable medical device, according to embodiments of the present disclosure.
  • FIGS 4A-5D show schematics of various embodiments of shape changing features for adjustable medical devices, according to embodiments of the present disclosure.
  • FIG. 6 illustrates a perspective view of another adjustable medical device, according to embodiments of the present disclosure.
  • FIGS. 7A-7E are section views of the left side of the heart illustrating a method of deploying an adjustable medical device at the mitral valve, according to embodiments of the present disclosure.
  • FIGS. 8A-8D are section views of the left side of the heart illustrating another embodiment of a method of deploying a, adjustable medical device at the mitral valve, according to embodiments of the present disclosure.
  • an adjustable medical device can comprise a slackened configuration and one or more stiffened configurations, the stiffened configurations comprising a predetermined curved shape.
  • the device can be locked into the stiffened configuration(s).
  • the device is percutaneously advanced to a target area within a patient in a slackened or relaxed configuration. Once the device is deployed to or positioned within a target area, it can be locked into a stiffened configuration comprising a predetermined curved shape.
  • Such a device can be used in a number of different applications, as described below.
  • FIG. 1A depicts an embodiment of an adjustable medical device 100 in an undeployed, straightened configuration lOOa.
  • the device 100 can comprise an elongate body.
  • the device 100 comprises an elongate, tubular body.
  • the device 100 can be shaped to be delivered percutaneously through or at the end of a catheter.
  • the device 100 comprises a plurality of slots openings 102 surrounding or extending from a spine portion 108.
  • the portion(s) of the device 100 comprising the openings 102 is the collapsing portion(s) 105 of the device 100.
  • the spine portion 108 of the device may be defined by an area of the bending portion 105 of the device 100 without openings 102.
  • the collapsing of the collapsing portion 105 allows the device 100 to bend at the spine portion 108 of the device 100.
  • the spine portion 108 can be thin, for example, comprising a width of about 0-10% of a circumference of the elongate body. In other embodiments, the spine portion 108 can be wider, for example, comprising greater than about 10% of a circumference of the elongate body.
  • the openings 102 surrounding the spine portion 108 are wedged-shaped. Other configurations for the openings are also possible (e.g., slit-shaped, rounded, etc.) as described herein.
  • the device 100 can be formed from a hyptotube.
  • the openings 102 can be formed by laser cutting, a blade, or the like as will be understood by one of ordinary skill in the art based on the description herein.
  • the device 100 may comprise a flexible covering or sleeve (e.g., a polymer covering). The cover can help protect surrounding tissue from trauma which may be caused by the openings 102 as the device 100 bends.
  • the shape or amount of bending of the device 100 in the stiffened configuration lOOb is defined by the difference in length between the outer edge of the curve (the spine portion 108) and the inner edge of the curve comprising the openings 102. This difference in length is determined by the width of the openings 102, the sum of which defines the difference in length between the inner and outer edge of the curve.
  • the device 100 may comprise a plug 112 positioned at a distal portion of the device 100.
  • a tension member 106 e.g., a wire, an elastic wire, or spring, or the like
  • the tension member 106 can hold the length of the inner radial surface of the curved portion of the device 100 at its minimal length. It will be appreciated by one of ordinary skill in the art based on the description herein that, in some embodiments, the device 100 may not comprise a plug 112, and the tension member 106 may be connected via another means to another distal point of the device 100.
  • the shuttle 104 is axially movable along a length of the device 100.
  • the shuttle 104 can comprise a cylinder, in some embodiments.
  • the shuttle 104 can be movable within the device 100, over the device 100, or partially within and over the device 100.
  • a pull member 110 e.g., wire, rod, etc.
  • the proximal end of the device 100 can be pushed distally while the shuttle 104 and/or pull member 110 is held in place.
  • the reduction in distance between the shuttle 104 and the proximal end of the device 100 may define the minimum length of the inner radial surface of the device 100.
  • the pull member 110 can be used to pull proximally, in the direction indicated by the arrow 114, on the shuttle 104.
  • the shuttle 104 moving proximally may cause the shape of the openings 102 to change.
  • the width of the openings 102 may decrease as the shuttle 104 moves proximally, thus shortening the side of device 100 positioned away from spine 108.
  • the shortening of one side of the device 100 causes the device 100 to curve away from the spine portion 108, as shown in FIG. 1B.
  • the device 100 can comprise a variety of shapes.
  • the device 100 shown in FIG. 1A may deform into the shape of a portion of a circle as shown in FIG. 1B.
  • the device 100 comprises a helical shaped device 140 as in FIGS. 1C and 1D in the stiffened configuration lOOa, l40a.
  • the helical shape can have a coil angle a, and a pitch p.
  • the coil angle a and coil pitch p of the device 140 in the stiffened configuration l40b can be determined by the angle and pitch of the spine portion 108 of the device 140.
  • the device 140 can comprise any combination of a spiral shape, a conical shape, a frustoconical shape, a helical shape, etc. As shown in the device 140 of FIGS. 1C and 1D, the openings 142 can be arranged at an angle relative to the spine 108 to facilitate helical coiling.
  • FIG. 1D illustrates a device 140 in a relaxed, straight configuration l40a, and in a stiffened, coiled configuration l40b.
  • FIG. 1E illustrates a magnified view of the portion of FIG. 1D shown in section A.
  • the slots or openings 142 are shown open in the relaxed, straight configuration l40a.
  • the slots or openings 142 may be collapsed, allowing the device 100 to curve.
  • the device 100 can comprise a locking mechanism to lock the shuttle 104 in a proximally pulled position.
  • FIGS. 2A and 2B show an embodiment of a locking mechanism 200.
  • FIG. 2A shows an external view of the device 100.
  • FIG. 2B shows a cut-away view of the device 100, showing the shuttle 104 within the device 100.
  • the locking mechanism 200 may comprise a track 202.
  • a pin 204 may be attached to the shuttle 104 and configured to slide along the track 202.
  • the track 202 may lead to a slot or opening 206 having a distal wall against which the pin 204 can rest, thereby preventing the pin 204 from moving distally and locking the shuttle 104 into position.
  • Other locking mechanisms 200 are also possible.
  • the shuttle 104 can be locked into position using a flexible screw running on the upper side of the shuttle 104.
  • the screw can be configured to be screwed into an anchor portion of the device 100 (e.g., plug 112). Turning the screw can cause the shuttle 104 to move towards or away from the anchor.
  • the screw can extend along the length of the spine portion 108. The screw may not extend out of the anchor when in the stiffened configuration as the spine 108 maintains its length between the collapsed and stiff configurations.
  • a screw and clip mechanism can be used.
  • FIGS. 3A-3B illustrate a detailed view of a locking mechanism 300 like the locking mechanism 200, further comprising a disengagement feature configured to allow the pull member 110 to disengage from the shuttle 104 when the shuttle 104 is pulled into a locked position.
  • FIGS. 3A and 3B illustrate the device 100 with the shuttle 104 pulled proximally along the track 202, but not yet placed into a locked position.
  • FIG. 3A shows the track 202 and the locking opening 206.
  • FIG. 3B shows a release window 302 positioned at a different portion of the device 100.
  • the shuttle 104 may twist, as shown in FIGS. 3C and 3D.
  • Various factors can influence the radius of curvature of the device 100 in the locked or stiffened configuration lOOb.
  • the configuration of the spine 108 can influence the configuration of the locked curvature.
  • a spine portion 108 that coils around the device 100 can produce a locked device with a helical configuration.
  • the coil angle and pitch of the spine portion 108 can determine the shape of the stiffened device as described herein.
  • the radius of curvature can be dependent on a total width of the openings.
  • FIGS. 4A and 4B show a device 400 with narrower openings 402 than those openings 412 shown in the device 410 of FIGS. 4C and 4D.
  • the device 410 with the wider openings 412 has a deeper curve (smaller radius of curvature) (FIG. 4D) that that of the device 400 with the smaller openings 402 (FIG. 4B).
  • the density of the openings or the frequency of the openings along the length of the device can also determine a radius of curvature of the device, as a device with a higher density of openings has a higher total width of the openings.
  • FIGS. 5A and 5B show a device 500 with fewer openings 502 than the device 510 of FIGS. 5C and 5D.
  • the device 510 with a higher density of openings 512 has a higher radius of curvature (FIG. 5D) than that of the device 500 with the less dense openings 502 (FIG. 5B).
  • any of the devices described herein may comprise any number, shape, or density of openings (e.g., 102, 142, 402, 412, 502, 512) as desired.
  • the device 100 may comprise multiple locking mechanisms 602 along a length of the device 100 as shown in FIG. 6.
  • multiple shuttles, tension members, and locking mechanisms can be used to separately and/or independently stiffen and lock various bending portions of the device 100.
  • Each bending portion may comprise a proximal anchor portion comprising a locking mechanism (e.g., similar to locking portion 206 of FIGS. 2A-2B) that can be placed into contact with the corresponding shuttle to cause the corresponding bending portion to curve.
  • a configuration can be used to sequentially lock portions of the device 100 and/or to achieve more complex stiffened configurations.
  • the deployed portions can be stiffened and locked.
  • This sequential locking can be performed manually by a clinician or, alternatively, can be performed by an automated system (e.g., a delivery system).
  • the act of exposing the device 100 or the relative motion between the delivery catheter and the device 100 can cause the exposed portions to be curved and locked.
  • a portion of the device 100 can comprise a first shape for delivery and a second, different shape when deployed.
  • a tip of the device 100 can be curved during delivery to aid with navigation.
  • the device 100 can be stiffened into a different shape when deployed.
  • multiple shuttles are used with the different locking mechanisms.
  • one shuttle can be locked into different positions, causing different portions of the device 100 to be curved. Allowing this sort of sequential stiffening of the device 100 can allow the device 100 to form the path it takes after exiting the delivery catheter, which can diminish the need for a guide wire or guide catheter.
  • the device 100 can be used as a dock for anchoring a valve prosthesis during a mitral valve repair or replacement procedure, as shown in FIGS. 7A-7E.
  • FIG. 7A illustrates delivery catheter 702 positioned through the atrial septum after transseptal puncture.
  • a guidewire 704 may be inserted into the heart via the delivery catheter 702 and through tissue at or near the anteromedial commissure, as shown in FIG. 7B.
  • the guidewire 704 may be advanced such that it coils around the chordae tendineae in the left ventricle, as shown in FIGS. 7B and 7C.
  • the device 100, or any of the devices described herein, may then be advanced through the catheter 702 and over the guidewire 704, as shown in FIG.
  • the device 100 can be inserted in a slackened configuration lOOa.
  • the shape of the device 100 may mimic the guidewire 704 during delivery to the chordae tendineae.
  • the device 100 Once the device 100 is deployed around the chordae tendineae, it can be locked into the stiffened configuration lOOb, as shown in FIG. 7E.
  • the device 100 may form a helical shape in the stiffened configuration lOOb with at least one coil around the chordae tendineae in the left ventricle and one coil in the left atrium.
  • the entire device 100 may be located in the left ventricle, with no coils sitting in the left atrium after deployment.
  • the guidewire 704 can be retracted once the device 100 is in place.
  • the device 100 may comprise multiple bending portions as described above with respect to FIG. 6. Retracting the guidewire 704 from the device 100 can be coordinated with locking the device 100 so that the device 100 is locked into shape from its distal end towards its proximal end as the distal tip of the guidewire 704 moves from the distal end towards the proximal end of the device 100 as it is retracted.
  • a valve prosthesis (not shown) may be delivered to the mitral valve and anchored to the mitral valve with the device 100 after the device 100 is deployed as described in U.S. Patent Application Nos. 16/594,946 and
  • FIGS. 8A-8D illustrate a similar method to that shown in FIGS. 7A-7E; however, in the method of FIGS. 8A-8D, the device 100 is deployed through a guide catheter 806 instead of over a guidewire 802.
  • FIG. 8A shows the delivery catheter 806 positioned through the atrial septum after transseptal puncture.
  • a guidewire 802 may then be inserted through tissue at or near the anteromedial commissure and advanced such that it coils around the chordae tendineae in the left ventricle, as shown in FIG. 8A.
  • the guide catheter 806 may be advanced over the guidewire 802, as shown in FIG. 8B.
  • the guidewire 802 may then be withdrawn.
  • the device 100 may then be advanced through the guide catheter 806, as shown in FIG. 8B.
  • the guide catheter 806 may then be withdrawn, as shown in FIG. 8C.
  • the device 100 may form a helical shape in the stiffened configuration with at least one coil around the chordae tendineae in the left ventricle and one coil in the left atrium.
  • the entire device 100 may be located in the left ventricle, with no coils sitting in the left atrium after deployment.
  • the guide catheter 806 can be retracted once the device 100 is in place.
  • the device 100 may comprise multiple bending portions as described above with respect to FIG. 6.
  • Retracting the guide catheter 806 from the device 100 can be coordinated with locking the device 100 so that the device 100 is locked into shape from its distal end towards its proximal end as the distal tip of the guide catheter 806 moves from the distal end towards the proximal end of the device 100 as it is retracted.
  • a valve prosthesis (not shown) may be delivered to the mitral valve and anchored to the mitral valve with the device 100 after the device 100 is deployed as described in U.S. Patent Application Nos. 16/594,946 and 16/546,901, and U.S. Provisional Application Nos.
  • the device 100 can be used in other configurations as well.
  • the device 100 can be used for non-occlusive ablation.
  • the device 100 can be advanced to an area to be treated in a slackened or relaxed configuration.
  • the device 100 can be locked into a stiffened configuration. In some embodiments, the device 100 can be moved into the stiffened
  • the stiffened configuration can comprise a predetermined curve configured to put the device 100 into contact with an area to be ablated.
  • the device 100 can be configured to coil around a perimeter of a blood vessel. The shape of the curve can be selected to ensure good contact between the device 100 and the area to be ablated.
  • the spine portion 108 can be the outer most portion of the device 100 when in the stiffened configuration.
  • the device 100 can comprise at least one electrode (e.g., 1, 2, 3, 4, 5, 6, 7, 8, or more electrodes) located such that they can be positioned against an area to be ablated in the stiffened
  • the device 100 can comprise a metal and serve as the electrode.
  • the device 100 in which the device 100 is used for non-occlusive ablation, the device 100 comprises a lumen through which blood can flow.
  • the device 100 can be used in an anchor for an embolic protection device such as a filter for use during a cardiac intervention procedure.
  • the device 100 can advantageously be delivered in a small profile and then deployed to a larger desired shape.
  • the devices described herein can have certain advantages over shape memory devices that are able to be delivered in a slack configuration and then assume a deployed shape upon delivery.
  • the devices described herein can comprise greater stiffness and strength in the deployed position than shape memory devices in a deployed position.
  • Shape memory devices having deployed configurations with a much greater diameter than the delivered configuration e.g., a coil
  • the devices of the current application are not biased during delivery and do not need to be held in place during delivery by a stronger or thicker catheter.
  • a feature or element When a feature or element is herein referred to as being“on” another feature or element, it can be directly on the other feature or element or intervening features and/or elements may also be present. In contrast, when a feature or element is referred to as being“directly on” another feature or element, there are no intervening features or elements present. It will also be understood that, when a feature or element is referred to as being“connected”,“attached” or “coupled” to another feature or element, it can be directly connected, attached or coupled to the other feature or element or intervening features or elements may be present.
  • references to a structure or feature that is disposed“adjacent” another feature may have portions that overlap or underlie the adjacent feature.
  • Terminology used herein is for the purpose of describing particular embodiments only and is not intended to be limiting of the invention.
  • the singular forms“a”,“an” and“the” are intended to include the plural forms as well, unless the context clearly indicates otherwise.
  • the terms“comprises” and/or “comprising,” when used in this specification, specify the presence of stated features, steps, operations, elements, and/or components, but do not preclude the presence or addition of one or more other features, steps, operations, elements, components, and/or groups thereof.
  • the term“and/or” includes any and all combinations of one or more of the associated listed items and may be abbreviated as“/”.
  • spatially relative terms such as“under”,“below”,“lower”,“over”,“upper” and the like, may be used herein for ease of description to describe one element or feature’s relationship to another element(s) or feature(s) as illustrated in the figures. It will be understood that the spatially relative terms are intended to encompass different orientations of the device in use or operation in addition to the orientation depicted in the figures. For example, if a device in the figures is inverted, elements described as“under” or“beneath” other elements or features would then be oriented“over” the other elements or features. Thus, the exemplary term“under” can encompass both an orientation of over and under.
  • the device may be otherwise oriented (rotated 90 degrees or at other orientations) and the spatially relative descriptors used herein interpreted accordingly.
  • the terms“upwardly”,“downwardly”,“vertical”,“horizontal” and the like are used herein for the purpose of explanation only unless specifically indicated otherwise.
  • first feature/element discussed below could be termed a second feature/element, and similarly, a second feature/element discussed below could be termed a first feature/element without departing from the teachings of the present disclosure.
  • the word“comprise”, and variations such as“comprises” and“comprising” means various components can be co-jointly employed in the methods and articles (e.g., compositions and apparatuses including device and methods).
  • the term“comprising” will be understood to imply the inclusion of any stated elements or steps but not the exclusion of any other elements or steps.
  • a numeric value may have a value that is +/- 0.1% of the stated value (or range of values), +/- 1% of the stated value (or range of values), +/- 2% of the stated value (or range of values), +/- 5% of the stated value (or range of values), +/- 10% of the stated value (or range of values), etc.
  • Any numerical values given herein should also be understood to include about or approximately that value, unless the context indicates otherwise. For example, if the value“10” is disclosed, then“about 10” is also disclosed. Any numerical range recited herein is intended to include all sub-ranges subsumed therein.

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CN201980076303.2A CN113056302B (zh) 2018-10-19 2019-10-18 可调节医疗装置
US17/286,724 US12403008B2 (en) 2018-10-19 2019-10-18 Adjustable medical device
JP2021521239A JP7489975B2 (ja) 2018-10-19 2019-10-18 調整可能な医療デバイス
EP19874300.7A EP3866900B1 (en) 2018-10-19 2019-10-18 Adjustable medical device
AU2019362078A AU2019362078B2 (en) 2018-10-19 2019-10-18 Adjustable medical device
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Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2021183610A1 (en) 2020-03-13 2021-09-16 Shifamed Holdings, Llc Prosthetic cardiac valve devices, systems, and methods
WO2021207545A1 (en) 2020-04-08 2021-10-14 Shifamed Holdings, Llc Valve delivery system
WO2022046678A1 (en) 2020-08-31 2022-03-03 Shifamed Holdings, Llc Interface for prosthetic cardiac valve and delivery systems
US11471282B2 (en) 2019-03-19 2022-10-18 Shifamed Holdings, Llc Prosthetic cardiac valve devices, systems, and methods
WO2022262117A1 (zh) * 2021-06-17 2022-12-22 上海臻亿医疗科技有限公司 一种心脏瓣膜的锚固装置
US11672657B2 (en) 2018-10-05 2023-06-13 Shifamed Holdings, Llc Prosthetic cardiac valve devices, systems, and methods
US11833034B2 (en) 2016-01-13 2023-12-05 Shifamed Holdings, Llc Prosthetic cardiac valve devices, systems, and methods
US12290456B2 (en) 2018-08-21 2025-05-06 Shifamed Holdings, Llc Prosthetic cardiac valve devices, systems, and methods

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114340562B (zh) * 2019-07-11 2025-07-29 梅德坦提亚国际有限公司 瓣环成形术装置
EP4203860A4 (en) 2020-08-31 2024-10-09 Shifamed Holdings, LLC PROSTHETIC IMPLANT DELIVERY SYSTEM
WO2022066720A1 (en) * 2020-09-22 2022-03-31 Shifamed Holdings, Llc Prosthetic cardiac valve sensor devices, systems, and methods with imaging
US12329635B2 (en) 2020-12-04 2025-06-17 Shifamed Holdings, Llc Flared prosthetic cardiac valve delivery devices and systems
US12201521B2 (en) 2021-03-22 2025-01-21 Shifamed Holdings, Llc Anchor position verification for prosthetic cardiac valve devices
CN114392013B (zh) * 2022-01-27 2025-08-19 科凯(南通)生命科学有限公司 通过收拢腱索修复三尖瓣反流的装置
CN114652432B (zh) * 2022-02-16 2023-06-20 上海玮启医疗器械有限公司 电极装置及消融导管
CN117045393A (zh) * 2022-05-06 2023-11-14 上海臻亿医疗科技有限公司 人工心脏瓣膜的锚固装置及人工心脏瓣膜系统

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5327905A (en) * 1992-02-14 1994-07-12 Boaz Avitall Biplanar deflectable catheter for arrhythmogenic tissue ablation
US8323241B2 (en) * 2009-06-24 2012-12-04 Shifamed Holdings, Llc Steerable medical delivery devices and methods of use
US8920369B2 (en) 2009-06-24 2014-12-30 Shifamed Holdings, Llc Steerable delivery sheaths
US9017408B2 (en) * 2010-02-16 2015-04-28 Nlt Spine Ltd. Medical device lock mechanism
WO2018112429A1 (en) 2016-12-16 2018-06-21 Edwards Lifesciences Corporation Deployment systems, tools, and methods for delivering an anchoring device for a prosthetic valve
US20180235443A1 (en) * 2011-01-31 2018-08-23 Boston Scientific Scimed, Inc. Articulation section with locking

Family Cites Families (629)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4725274A (en) 1986-10-24 1988-02-16 Baxter Travenol Laboratories, Inc. Prosthetic heart valve
US5002563A (en) 1990-02-22 1991-03-26 Raychem Corporation Sutures utilizing shape memory alloys
US5370685A (en) 1991-07-16 1994-12-06 Stanford Surgical Technologies, Inc. Endovascular aortic valve replacement
US5356424A (en) 1993-02-05 1994-10-18 American Cyanamid Co. Laparoscopic suturing device
US5873835A (en) 1993-04-29 1999-02-23 Scimed Life Systems, Inc. Intravascular pressure and flow sensor
US5582616A (en) 1994-08-05 1996-12-10 Origin Medsystems, Inc. Surgical helical fastener with applicator
JPH08131551A (ja) 1994-11-04 1996-05-28 Yoshimasa Obayashi 血栓除去用カテーテル
US5997526A (en) 1996-03-25 1999-12-07 The Uab Research Foundation Shape memory catheter
US7238197B2 (en) 2000-05-30 2007-07-03 Devax, Inc. Endoprosthesis deployment system for treating vascular bifurcations
US5779669A (en) 1996-10-28 1998-07-14 C. R. Bard, Inc. Steerable catheter with fixed curve
US5716397A (en) 1996-12-06 1998-02-10 Medtronic, Inc. Annuloplasty device with removable stiffening element
EP0850607A1 (en) 1996-12-31 1998-07-01 Cordis Corporation Valve prosthesis for implantation in body channels
WO1998029030A1 (en) 1997-01-03 1998-07-09 Biosense Inc. Pressure-sensing stent
US5944690A (en) 1997-03-17 1999-08-31 C.R. Bard, Inc. Slidable control mechanism for steerable catheter
US5755601A (en) 1997-03-17 1998-05-26 Brunswick Corporation Brake system for personal watercraft
US6530952B2 (en) 1997-12-29 2003-03-11 The Cleveland Clinic Foundation Bioprosthetic cardiovascular valve system
US6048339A (en) 1998-06-29 2000-04-11 Endius Incorporated Flexible surgical instruments with suction
DE69914609T2 (de) 1998-08-19 2005-01-05 Cook Inc., Bloomington Vorgeformter Führungsdraht
DE19857887B4 (de) 1998-12-15 2005-05-04 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Verankerungsstütze für eine Herzklappenprothese
US7811296B2 (en) 1999-04-09 2010-10-12 Evalve, Inc. Fixation devices for variation in engagement of tissue
ATE484241T1 (de) 1999-04-09 2010-10-15 Evalve Inc Verfahren und vorrichtung zur herzklappenreperation
US20040044350A1 (en) 1999-04-09 2004-03-04 Evalve, Inc. Steerable access sheath and methods of use
US6752813B2 (en) 1999-04-09 2004-06-22 Evalve, Inc. Methods and devices for capturing and fixing leaflets in valve repair
US10327743B2 (en) 1999-04-09 2019-06-25 Evalve, Inc. Device and methods for endoscopic annuloplasty
US8216256B2 (en) 1999-04-09 2012-07-10 Evalve, Inc. Detachment mechanism for implantable fixation devices
US7666204B2 (en) 1999-04-09 2010-02-23 Evalve, Inc. Multi-catheter steerable guiding system and methods of use
ATE342089T1 (de) 1999-06-02 2006-11-15 Boston Scient Ltd Arzneimittelabgabevorrichtungen
DE19933278C2 (de) 1999-07-14 2001-11-29 Biotronik Mess & Therapieg Steuerbarer Katheter
US8579966B2 (en) 1999-11-17 2013-11-12 Medtronic Corevalve Llc Prosthetic valve for transluminal delivery
US6458153B1 (en) 1999-12-31 2002-10-01 Abps Venture One, Ltd. Endoluminal cardiac and venous valve prostheses and methods of manufacture and delivery thereof
US6797002B2 (en) 2000-02-02 2004-09-28 Paul A. Spence Heart valve repair apparatus and methods
US6419695B1 (en) 2000-05-22 2002-07-16 Shlomo Gabbay Cardiac prosthesis for helping improve operation of a heart valve
US6419696B1 (en) 2000-07-06 2002-07-16 Paul A. Spence Annuloplasty devices and related heart valve repair methods
US7077861B2 (en) 2000-07-06 2006-07-18 Medtentia Ab Annuloplasty instrument
US6974476B2 (en) 2003-05-05 2005-12-13 Rex Medical, L.P. Percutaneous aortic valve
US8202315B2 (en) 2001-04-24 2012-06-19 Mitralign, Inc. Catheter-based annuloplasty using ventricularly positioned catheter
FR2826863B1 (fr) 2001-07-04 2003-09-26 Jacques Seguin Ensemble permettant la mise en place d'une valve prothetique dans un conduit corporel
EP1432369B1 (en) 2001-08-31 2008-02-27 Mitral Interventions Apparatus for valve repair
US20060052821A1 (en) 2001-09-06 2006-03-09 Ovalis, Inc. Systems and methods for treating septal defects
US6893460B2 (en) 2001-10-11 2005-05-17 Percutaneous Valve Technologies Inc. Implantable prosthetic valve
US6908478B2 (en) 2001-12-05 2005-06-21 Cardiac Dimensions, Inc. Anchor and pull mitral valve device and method
US7201771B2 (en) 2001-12-27 2007-04-10 Arbor Surgical Technologies, Inc. Bioprosthetic heart valve
US8308797B2 (en) 2002-01-04 2012-11-13 Colibri Heart Valve, LLC Percutaneously implantable replacement heart valve device and method of making same
WO2003105670A2 (en) 2002-01-10 2003-12-24 Guided Delivery Systems, Inc. Devices and methods for heart valve repair
AU2003225766A1 (en) 2002-03-11 2003-09-29 Wardle, John, L. Surgical coils and methods of deploying
AU2003247526A1 (en) 2002-06-12 2003-12-31 Mitral Interventions, Inc. Method and apparatus for tissue connection
US8641727B2 (en) 2002-06-13 2014-02-04 Guided Delivery Systems, Inc. Devices and methods for heart valve repair
US7753924B2 (en) 2003-09-04 2010-07-13 Guided Delivery Systems, Inc. Delivery devices and methods for heart valve repair
US7594903B2 (en) 2002-09-25 2009-09-29 Abbott Cardiovascular Systems Inc. Controlling shaft bending moment and whipping in a tendon deflection or other tendon system
US20050119735A1 (en) 2002-10-21 2005-06-02 Spence Paul A. Tissue fastening systems and methods utilizing magnetic guidance
JP2004154177A (ja) 2002-11-01 2004-06-03 Olympus Corp 内視鏡
US7175656B2 (en) 2003-04-18 2007-02-13 Alexander Khairkhahan Percutaneous transcatheter heart valve replacement
US10631871B2 (en) 2003-05-19 2020-04-28 Evalve, Inc. Fixation devices, systems and methods for engaging tissue
US20070255396A1 (en) 2003-06-20 2007-11-01 Medtronic Vascular, Inc. Chrodae Tendinae Girdle
AU2004258942B2 (en) 2003-07-21 2009-12-03 The Trustees Of The University Of Pennsylvania Percutaneous heart valve
US7160322B2 (en) 2003-08-13 2007-01-09 Shlomo Gabbay Implantable cardiac prosthesis for mitigating prolapse of a heart valve
US8021421B2 (en) 2003-08-22 2011-09-20 Medtronic, Inc. Prosthesis heart valve fixturing device
EP1689329A2 (en) * 2003-11-12 2006-08-16 Medtronic Vascular, Inc. Cardiac valve annulus reduction system
US20050165344A1 (en) 2003-11-26 2005-07-28 Dobak John D.Iii Method and apparatus for treating heart failure
US9526609B2 (en) 2003-12-23 2016-12-27 Boston Scientific Scimed, Inc. Methods and apparatus for endovascularly replacing a patient's heart valve
US7445631B2 (en) 2003-12-23 2008-11-04 Sadra Medical, Inc. Methods and apparatus for endovascularly replacing a patient's heart valve
US20050137686A1 (en) 2003-12-23 2005-06-23 Sadra Medical, A Delaware Corporation Externally expandable heart valve anchor and method
US8287584B2 (en) 2005-11-14 2012-10-16 Sadra Medical, Inc. Medical implant deployment tool
US8343213B2 (en) 2003-12-23 2013-01-01 Sadra Medical, Inc. Leaflet engagement elements and methods for use thereof
US7748389B2 (en) 2003-12-23 2010-07-06 Sadra Medical, Inc. Leaflet engagement elements and methods for use thereof
US20050137691A1 (en) 2003-12-23 2005-06-23 Sadra Medical Two piece heart valve and anchor
US20050137694A1 (en) 2003-12-23 2005-06-23 Haug Ulrich R. Methods and apparatus for endovascularly replacing a patient's heart valve
US7381219B2 (en) 2003-12-23 2008-06-03 Sadra Medical, Inc. Low profile heart valve and delivery system
US8182528B2 (en) 2003-12-23 2012-05-22 Sadra Medical, Inc. Locking heart valve anchor
US8603160B2 (en) 2003-12-23 2013-12-10 Sadra Medical, Inc. Method of using a retrievable heart valve anchor with a sheath
US7824442B2 (en) 2003-12-23 2010-11-02 Sadra Medical, Inc. Methods and apparatus for endovascularly replacing a heart valve
US7824443B2 (en) 2003-12-23 2010-11-02 Sadra Medical, Inc. Medical implant delivery and deployment tool
US7959666B2 (en) 2003-12-23 2011-06-14 Sadra Medical, Inc. Methods and apparatus for endovascularly replacing a heart valve
US7329279B2 (en) 2003-12-23 2008-02-12 Sadra Medical, Inc. Methods and apparatus for endovascularly replacing a patient's heart valve
US9005273B2 (en) 2003-12-23 2015-04-14 Sadra Medical, Inc. Assessing the location and performance of replacement heart valves
US20050137696A1 (en) 2003-12-23 2005-06-23 Sadra Medical Apparatus and methods for protecting against embolization during endovascular heart valve replacement
US8828078B2 (en) 2003-12-23 2014-09-09 Sadra Medical, Inc. Methods and apparatus for endovascular heart valve replacement comprising tissue grasping elements
US8579962B2 (en) 2003-12-23 2013-11-12 Sadra Medical, Inc. Methods and apparatus for performing valvuloplasty
US8840663B2 (en) 2003-12-23 2014-09-23 Sadra Medical, Inc. Repositionable heart valve method
US20050137687A1 (en) 2003-12-23 2005-06-23 Sadra Medical Heart valve anchor and method
US7780725B2 (en) 2004-06-16 2010-08-24 Sadra Medical, Inc. Everting heart valve
US7166127B2 (en) 2003-12-23 2007-01-23 Mitralign, Inc. Tissue fastening systems and methods utilizing magnetic guidance
US8500774B2 (en) 2004-01-22 2013-08-06 Rex Medical, L.P. Vein filter
EP1718246A4 (en) 2004-02-05 2009-11-18 Childrens Medical Center TRANSCATHETER DELIVERY OF A HEARTLAPPROTHESIS
WO2005087139A1 (en) 2004-03-15 2005-09-22 Baker Medical Research Institute Treating valve failure
US20050240202A1 (en) 2004-04-21 2005-10-27 Hani Shennib Devices and methods of repairing cardiac valves
EP1750592B1 (en) 2004-05-14 2016-12-28 Evalve, Inc. Locking mechanisms for fixation devices
US7678135B2 (en) 2004-06-09 2010-03-16 Usgi Medical, Inc. Compressible tissue anchor assemblies
US20050277839A1 (en) 2004-06-10 2005-12-15 Honeywell International, Inc. Wireless flow measurement in arterial stent
US20050278023A1 (en) 2004-06-10 2005-12-15 Zwirkoski Paul A Method and apparatus for filling a cavity
US20070135913A1 (en) 2004-06-29 2007-06-14 Micardia Corporation Adjustable annuloplasty ring activation system
US9061120B2 (en) 2004-08-05 2015-06-23 Oscor Inc. Catheter control mechanism and steerable catheter
JP2008513060A (ja) 2004-09-14 2008-05-01 エドワーズ ライフサイエンシーズ アーゲー 心臓弁逆流の処置のためのデバイスおよび方法
AU2004324043A1 (en) 2004-10-02 2006-04-20 Christoph Hans Huber Methods and devices for repair or replacement of heart valves or adjacent tissue without the need for full cardiopulmonary support
WO2009053952A2 (en) 2007-10-26 2009-04-30 Mednua Limited A medical device for use in treatment of a valve
EP1841383A1 (en) 2004-12-15 2007-10-10 Mednua Limited A medical device suitable for use in treatment of a valve
US7731705B2 (en) 2005-01-10 2010-06-08 Wardle John L Eluting coils and methods of deploying and retrieving
US10064540B2 (en) 2005-02-02 2018-09-04 Intuitive Surgical Operations, Inc. Visualization apparatus for transseptal access
AU2006212750B2 (en) 2005-02-07 2011-11-17 Evalve, Inc. Methods, systems and devices for cardiac valve repair
US20100312333A1 (en) 2009-04-29 2010-12-09 The Cleveland Clinic Foundation Apparatus and method for replacing a diseased cardiac valve
US7955385B2 (en) 2005-02-28 2011-06-07 Medtronic Vascular, Inc. Device, system, and method for aiding valve annuloplasty
CN101340861B (zh) 2005-02-28 2011-08-10 梅德坦提亚国际有限公司 用于改善心脏瓣膜功能的装置和成套工具
US7914569B2 (en) 2005-05-13 2011-03-29 Medtronics Corevalve Llc Heart valve prosthesis and methods of manufacture and use
US20060293698A1 (en) 2005-06-28 2006-12-28 Medtronic Vascular, Inc. Retainer device for mitral valve leaflets
JP2007020797A (ja) 2005-07-14 2007-02-01 Olympus Medical Systems Corp 内視鏡
US20070027533A1 (en) 2005-07-28 2007-02-01 Medtronic Vascular, Inc. Cardiac valve annulus restraining device
US20070038292A1 (en) 2005-08-09 2007-02-15 Moise Danielpour Bio-absorbable stent
US20070055206A1 (en) 2005-08-10 2007-03-08 Guided Delivery Systems, Inc. Methods and devices for deployment of tissue anchors
MX2008002552A (es) 2005-09-07 2008-04-21 Medtentia Ab Un dispositivo y un metodo para mejorar la funcion de una valvula cardiaca.
DE102005052628B4 (de) 2005-11-04 2014-06-05 Jenavalve Technology Inc. Selbstexpandierendes, flexibles Drahtgeflecht mit integrierter Klappenprothese für den transvaskulären Herzklappenersatz und ein System mit einer solchen Vorrichtung und einem Einführkatheter
US20080275540A1 (en) 2005-11-09 2008-11-06 Ning Wen Artificial Heart Valve Stent and Weaving Method Thereof
US20070118151A1 (en) 2005-11-21 2007-05-24 The Brigham And Women's Hospital, Inc. Percutaneous cardiac valve repair with adjustable artificial chordae
WO2007100410A2 (en) 2005-12-15 2007-09-07 Georgia Tech Research Corporation Systems and methods for enabling heart valve replacement
US20070142907A1 (en) 2005-12-16 2007-06-21 Micardia Corporation Adjustable prosthetic valve implant
US20070213813A1 (en) 2005-12-22 2007-09-13 Symetis Sa Stent-valves for valve replacement and associated methods and systems for surgery
WO2007081820A1 (en) 2006-01-09 2007-07-19 Children's Medical Center Corporation Transcatheter delivery of a replacement heart valve
US8562645B2 (en) 2006-09-29 2013-10-22 Biomet Sports Medicine, Llc Method and apparatus for forming a self-locking adjustable loop
US7637946B2 (en) 2006-02-09 2009-12-29 Edwards Lifesciences Corporation Coiled implant for mitral valve repair
EP1988851A2 (en) 2006-02-14 2008-11-12 Sadra Medical, Inc. Systems and methods for delivering a medical implant
EP2583640B1 (en) 2006-02-16 2022-06-22 Venus MedTech (HangZhou), Inc. Minimally invasive replacement heart valve
US8403981B2 (en) 2006-02-27 2013-03-26 CardiacMC, Inc. Methods and devices for delivery of prosthetic heart valves and other prosthetics
US8147541B2 (en) 2006-02-27 2012-04-03 Aortx, Inc. Methods and devices for delivery of prosthetic heart valves and other prosthetics
US9402633B2 (en) 2006-03-13 2016-08-02 Pneumrx, Inc. Torque alleviating intra-airway lung volume reduction compressive implant structures
US8075615B2 (en) 2006-03-28 2011-12-13 Medtronic, Inc. Prosthetic cardiac valve formed from pericardium material and methods of making same
US8070800B2 (en) 2006-05-05 2011-12-06 Children's Medical Center Corporation Transcatheter heart valve prostheses
IE20070428A1 (en) 2006-06-15 2007-12-21 Mednua Ltd A medical device suitable for use in treatment of a valve
US8449605B2 (en) 2006-06-28 2013-05-28 Kardium Inc. Method for anchoring a mitral valve
US20080004696A1 (en) 2006-06-29 2008-01-03 Valvexchange Inc. Cardiovascular valve assembly with resizable docking station
US8870916B2 (en) 2006-07-07 2014-10-28 USGI Medical, Inc Low profile tissue anchors, tissue anchor systems, and methods for their delivery and use
JP2008018139A (ja) 2006-07-14 2008-01-31 Terumo Corp 骨補填材及び骨補填材組立体
FR2905260B1 (fr) 2006-09-04 2010-06-04 Univ Paris Curie Endoprothese et procede de fabrication d'une endoprothese.
US8834564B2 (en) 2006-09-19 2014-09-16 Medtronic, Inc. Sinus-engaging valve fixation member
US8876894B2 (en) 2006-09-19 2014-11-04 Medtronic Ventor Technologies Ltd. Leaflet-sensitive valve fixation member
US7534261B2 (en) 2006-10-02 2009-05-19 Edwards Lifesciences Corporation Sutureless heart valve attachment
US7935144B2 (en) 2006-10-19 2011-05-03 Direct Flow Medical, Inc. Profile reduction of valve implant
AU2012261727B2 (en) 2006-11-13 2015-10-29 Medtentia International Ltd Oy Device and Method for Improving Function of Heart Valve
SE530568C2 (sv) 2006-11-13 2008-07-08 Medtentia Ab Anordning och metod för förbättring av funktionen hos en hjärtklaff
AU2007231733B2 (en) 2006-11-28 2014-03-13 Cathrx Ltd A catheter steering system
US20080208327A1 (en) 2007-02-27 2008-08-28 Rowe Stanton J Method and apparatus for replacing a prosthetic valve
US11660190B2 (en) 2007-03-13 2023-05-30 Edwards Lifesciences Corporation Tissue anchors, systems and methods, and devices
FR2915087B1 (fr) 2007-04-20 2021-11-26 Corevalve Inc Implant de traitement d'une valve cardiaque, en particulier d'une valve mitrale, materiel inculant cet implant et materiel de mise en place de cet implant.
US20090030504A1 (en) 2007-07-27 2009-01-29 Boston Scientific Scimed, Inc. Medical devices comprising porous inorganic fibers for the release of therapeutic agents
US9814611B2 (en) 2007-07-31 2017-11-14 Edwards Lifesciences Cardiaq Llc Actively controllable stent, stent graft, heart valve and method of controlling same
EP2219558B8 (en) 2007-08-21 2015-09-23 Symetis SA Stent-valves for valve replacement and associated systems for surgery
AU2008288796B2 (en) 2007-08-23 2014-03-20 Dfm, Llc Cardiovascular prosthetic valve
BRPI0817708A2 (pt) 2007-09-26 2017-05-16 St Jude Medical válvula cardíaca protética, e, estrutura de lamela para a mesma.
US9532868B2 (en) 2007-09-28 2017-01-03 St. Jude Medical, Inc. Collapsible-expandable prosthetic heart valves with structures for clamping native tissue
US8454686B2 (en) 2007-09-28 2013-06-04 St. Jude Medical, Inc. Two-stage collapsible/expandable prosthetic heart valves and anchoring systems
US20090093826A1 (en) 2007-10-05 2009-04-09 Cardica, Inc. Patent Foramen Ovale Closure System
US20090138079A1 (en) 2007-10-10 2009-05-28 Vector Technologies Ltd. Prosthetic heart valve for transfemoral delivery
US10856970B2 (en) 2007-10-10 2020-12-08 Medtronic Ventor Technologies Ltd. Prosthetic heart valve for transfemoral delivery
US8313526B2 (en) 2007-11-19 2012-11-20 Cook Medical Technologies Llc Valve frame
US9526487B2 (en) 2007-12-05 2016-12-27 Indiana University Research & Technology Corporation Methods and apparatuses for delivering anchoring devices into body passage walls
EP2231070B1 (en) 2007-12-14 2013-05-22 Edwards Lifesciences Corporation Leaflet attachment frame for a prosthetic valve
EP2072027B1 (en) 2007-12-21 2020-06-17 Medtentia International Ltd Oy pre-annuloplasty device and method
US8157853B2 (en) 2008-01-24 2012-04-17 Medtronic, Inc. Delivery systems and methods of implantation for prosthetic heart valves
AU2009206340B2 (en) 2008-01-24 2012-06-14 Medtronic Vascular Inc. Infundibular reducer device delivery system and related methods
AU2009212393B2 (en) 2008-02-06 2014-07-24 Ancora Heart, Inc. Multi-window guide tunnel
US20090209950A1 (en) 2008-02-20 2009-08-20 Guided Delivery Systems Inc. Electrophysiology catheter system
US8998933B2 (en) 2008-02-28 2015-04-07 Medtronic, Inc. Surgical fastening clips, systems and methods for proximating tissue
US8968393B2 (en) 2008-02-28 2015-03-03 Medtronic, Inc. System and method for percutaneous mitral valve repair
DE102008012113A1 (de) 2008-03-02 2009-09-03 Transcatheter Technologies Gmbh Stent, welcher vom expandierten Zustand erneut im Durchmesser kontrolliert verringerbar ist
US8382829B1 (en) 2008-03-10 2013-02-26 Mitralign, Inc. Method to reduce mitral regurgitation by cinching the commissure of the mitral valve
FR2930137B1 (fr) 2008-04-18 2010-04-23 Corevalve Inc Materiel de traitement d'une valve cardiaque, en particulier d'une valve mitrale.
DK3967274T4 (da) 2008-04-23 2025-08-25 Medtronic Inc Hjerteklapanordninger med stent
BRPI0911351B8 (pt) 2008-04-23 2021-06-22 Medtronic Inc estrutura de stent para uma válvula cardíaca protética, e, prótese de válvula cardíaca
US20090276040A1 (en) 2008-05-01 2009-11-05 Edwards Lifesciences Corporation Device and method for replacing mitral valve
US8096985B2 (en) 2008-05-07 2012-01-17 Guided Delivery Systems Inc. Deflectable guide
US20090287304A1 (en) 2008-05-13 2009-11-19 Kardium Inc. Medical Device for Constricting Tissue or a Bodily Orifice, for example a mitral valve
US8323335B2 (en) 2008-06-20 2012-12-04 Edwards Lifesciences Corporation Retaining mechanisms for prosthetic valves and methods for using
US20100010520A1 (en) 2008-07-11 2010-01-14 Olympus Medical Systems Corp. Tissue fastener
US8652202B2 (en) 2008-08-22 2014-02-18 Edwards Lifesciences Corporation Prosthetic heart valve and delivery apparatus
US9314335B2 (en) 2008-09-19 2016-04-19 Edwards Lifesciences Corporation Prosthetic heart valve configured to receive a percutaneous prosthetic heart valve implantation
US8287591B2 (en) 2008-09-19 2012-10-16 Edwards Lifesciences Corporation Transformable annuloplasty ring configured to receive a percutaneous prosthetic heart valve implantation
CN102292053A (zh) 2008-09-29 2011-12-21 卡迪尔克阀门技术公司 心脏瓣膜
JP5607639B2 (ja) 2008-10-10 2014-10-15 サドラ メディカル インコーポレイテッド 医療用デバイス・システム
US20110046600A1 (en) 2008-12-05 2011-02-24 Crank Justin M Devices, systems, and related methods for delivery of fluid to tissue
US8940044B2 (en) 2011-06-23 2015-01-27 Valtech Cardio, Ltd. Closure element for use with an annuloplasty structure
US8545553B2 (en) 2009-05-04 2013-10-01 Valtech Cardio, Ltd. Over-wire rotation tool
US10517719B2 (en) 2008-12-22 2019-12-31 Valtech Cardio, Ltd. Implantation of repair devices in the heart
US8147542B2 (en) 2008-12-22 2012-04-03 Valtech Cardio, Ltd. Adjustable repair chords and spool mechanism therefor
EP3848002A1 (en) 2008-12-22 2021-07-14 Valtech Cardio, Ltd. Adjustable annuloplasty devices and adjustment mechanisms therefor
US8926697B2 (en) 2011-06-23 2015-01-06 Valtech Cardio, Ltd. Closed band for percutaneous annuloplasty
US8241351B2 (en) 2008-12-22 2012-08-14 Valtech Cardio, Ltd. Adjustable partial annuloplasty ring and mechanism therefor
US8808368B2 (en) 2008-12-22 2014-08-19 Valtech Cardio, Ltd. Implantation of repair chords in the heart
US8715342B2 (en) 2009-05-07 2014-05-06 Valtech Cardio, Ltd. Annuloplasty ring with intra-ring anchoring
US9011530B2 (en) 2008-12-22 2015-04-21 Valtech Cardio, Ltd. Partially-adjustable annuloplasty structure
US20100198208A1 (en) 2009-01-20 2010-08-05 Napp Malte I Diagnostic catheters, guide catheters, visualization devices and chord manipulation devices, and related kits and methods
WO2010085456A1 (en) 2009-01-20 2010-07-29 Guided Delivery Systems Inc. Anchor deployment devices and related methods
WO2010093837A2 (en) 2009-02-11 2010-08-19 Tendyne Medical, Inc. Percutaneous mitral annular stitch to decrease mitral regurgitation
US8348997B2 (en) 2009-02-24 2013-01-08 Medtronic Vascular, Inc. One-way replacement valve
WO2010098857A1 (en) 2009-02-27 2010-09-02 St. Jude Medical, Inc. Stent features for collapsible prosthetic heart valves
CN101919753A (zh) 2009-03-30 2010-12-22 卡迪万蒂奇医药公司 人工主动脉瓣膜或二尖瓣膜的无缝合移植方法和装置
AU2010236288A1 (en) 2009-04-15 2011-10-20 Cardiaq Valve Technologies, Inc. Vascular implant and delivery system
US9968452B2 (en) 2009-05-04 2018-05-15 Valtech Cardio, Ltd. Annuloplasty ring delivery cathethers
US8523881B2 (en) 2010-07-26 2013-09-03 Valtech Cardio, Ltd. Multiple anchor delivery tool
WO2010141847A1 (en) 2009-06-05 2010-12-09 Ats Medical, Inc. Flexible commissure structure for attaching valve bioprosthesis
CA2767035C (en) 2009-07-02 2015-07-21 The Cleveland Clinic Foundation Apparatus and method for replacing a diseased cardiac valve
JP5744028B2 (ja) 2009-08-27 2015-07-01 メドトロニック，インコーポレイテッド 経カテーテル弁搬送システムおよび方法
CN102548508B (zh) 2009-09-21 2015-06-03 麦德托尼克公司 带支架的经导管假体心脏瓣膜输送系统及方法
US9730790B2 (en) 2009-09-29 2017-08-15 Edwards Lifesciences Cardiaq Llc Replacement valve and method
US8652203B2 (en) 2010-09-23 2014-02-18 Cardiaq Valve Technologies, Inc. Replacement heart valves, delivery devices and methods
US9180007B2 (en) 2009-10-29 2015-11-10 Valtech Cardio, Ltd. Apparatus and method for guide-wire based advancement of an adjustable implant
WO2011154942A2 (en) 2010-06-07 2011-12-15 Valtech Cardio, Ltd. Apparatus and method for guide-wire based advancement of a rotation assembly
DE102009055969A1 (de) 2009-11-27 2011-06-01 Transcatheter Technologies Gmbh Vorrichtung und Set zum Falten oder Entfalten eines medizinischen Implantats und Verfahren
US8449599B2 (en) 2009-12-04 2013-05-28 Edwards Lifesciences Corporation Prosthetic valve for replacing mitral valve
WO2011069154A2 (en) 2009-12-05 2011-06-09 Integrated Sensing Systems, Inc. Delivery system, method, and anchor for medical implant placement
US8715300B2 (en) 2009-12-05 2014-05-06 Integrated Sensing Systems, Inc. Delivery system, method, and anchor for medical implant placement
EP3300695B1 (en) 2009-12-08 2023-05-24 Avalon Medical Ltd. Device and system for transcatheter mitral valve replacement
US8870950B2 (en) 2009-12-08 2014-10-28 Mitral Tech Ltd. Rotation-based anchoring of an implant
CN102113921A (zh) 2009-12-30 2011-07-06 微创医疗器械(上海)有限公司 一种介入式心脏瓣膜
US9072603B2 (en) 2010-02-24 2015-07-07 Medtronic Ventor Technologies, Ltd. Mitral prosthesis and methods for implantation
US8795354B2 (en) 2010-03-05 2014-08-05 Edwards Lifesciences Corporation Low-profile heart valve and delivery system
CN102869321B (zh) 2010-03-05 2015-05-06 爱德华兹生命科学公司 人工瓣膜锁紧机构
US20110224785A1 (en) 2010-03-10 2011-09-15 Hacohen Gil Prosthetic mitral valve with tissue anchors
US9320597B2 (en) 2010-03-30 2016-04-26 Medtronic, Inc. Transcatheter prosthetic heart valve delivery system with recapturing feature and method
US8652204B2 (en) 2010-04-01 2014-02-18 Medtronic, Inc. Transcatheter valve with torsion spring fixation and related systems and methods
US8998980B2 (en) 2010-04-09 2015-04-07 Medtronic, Inc. Transcatheter prosthetic heart valve delivery system with recapturing feature and method
US8512401B2 (en) 2010-04-12 2013-08-20 Medtronic, Inc. Transcatheter prosthetic heart valve delivery system with funnel recapturing feature and method
US8465541B2 (en) 2010-04-19 2013-06-18 Medtronic, Inc. Transcatheter prosthetic heart valve delivery system and method with expandable stability tube
US8740976B2 (en) 2010-04-21 2014-06-03 Medtronic, Inc. Transcatheter prosthetic heart valve delivery system with flush report
US8623075B2 (en) 2010-04-21 2014-01-07 Medtronic, Inc. Transcatheter prosthetic heart valve delivery system and method with controlled expansion of prosthetic heart valve
WO2011139746A1 (en) 2010-04-27 2011-11-10 Medtronic Inc. Transcatheter prosthetic heart valve delivery device with passive trigger release
AU2011248658B2 (en) 2010-04-27 2014-09-11 Medtronic Inc. Transcatheter prosthetic heart valve delivery device with biased release features
US8579964B2 (en) 2010-05-05 2013-11-12 Neovasc Inc. Transcatheter mitral valve prosthesis
CN103002833B (zh) 2010-05-25 2016-05-11 耶拿阀门科技公司 人工心脏瓣及包括人工心脏瓣和支架的经导管输送的内假体
US9561102B2 (en) 2010-06-02 2017-02-07 Medtronic, Inc. Transcatheter delivery system and method with controlled expansion and contraction of prosthetic heart valve
EP3061422B1 (en) 2010-06-21 2021-11-03 Edwards Lifesciences CardiAQ LLC Replacement heart valve
EP2962664B1 (en) 2010-07-09 2022-05-11 Highlife SAS Transcatheter atrio-ventricular valve prosthesis
US8657872B2 (en) 2010-07-19 2014-02-25 Jacques Seguin Cardiac valve repair system and methods of use
US9132009B2 (en) 2010-07-21 2015-09-15 Mitraltech Ltd. Guide wires with commissural anchors to advance a prosthetic valve
WO2012012761A2 (en) 2010-07-23 2012-01-26 Edwards Lifesciences Corporation Retaining mechanisms for prosthetic valves
US10130470B2 (en) 2010-08-17 2018-11-20 St. Jude Medical, Llc Sleeve for facilitating movement of a transfemoral catheter
US20120053680A1 (en) 2010-08-24 2012-03-01 Bolling Steven F Reconfiguring Heart Features
WO2012030598A2 (en) 2010-09-01 2012-03-08 Medtronic Vascular Galway Limited Prosthetic valve support structure
US10105224B2 (en) 2010-09-01 2018-10-23 Mvalve Technologies Ltd. Cardiac valve support structure
EP2611391B1 (en) 2010-09-01 2017-11-22 Mvalve Technologies Ltd. Cardiac valve support structure
AU2011300644B2 (en) 2010-09-10 2015-08-20 Symetis Sa Valve replacement devices and a system comprising the valve replacement device and a delivery device therefor
CN103118630B (zh) 2010-09-24 2016-05-04 西美蒂斯股份公司 支架瓣膜、输送设备和输送方法
US8940002B2 (en) 2010-09-30 2015-01-27 Kardium Inc. Tissue anchor system
PL3593762T3 (pl) 2010-10-05 2021-05-04 Edwards Lifesciences Corporation Zastawka protetyczna serca i urządzenie do wprowadzania
EP2629699B1 (en) 2010-10-21 2017-01-04 Medtronic, Inc. Mitral bioprosthesis with low ventricular profile
IT1402571B1 (it) 2010-11-12 2013-09-13 Ht Consultant Di Giovanni Righini Sistema protesico per valvola cardio-vascolare con struttura di ancoraggio separata
CA2822381C (en) 2010-12-23 2019-04-02 Foundry Newco Xii, Inc. System for mitral valve repair and replacement
EP2474287A1 (en) 2011-01-11 2012-07-11 Symetis Sa Delivery catheter for stent-valve, and sub-assembly therefor
EP2478868A1 (en) 2011-01-25 2012-07-25 The Provost, Fellows, Foundation Scholars, and the other Members of Board, of the College of the Holy and Undivided Trinity of Queen Elizabeth Implant device
US8845717B2 (en) 2011-01-28 2014-09-30 Middle Park Medical, Inc. Coaptation enhancement implant, system, and method
US8888843B2 (en) 2011-01-28 2014-11-18 Middle Peak Medical, Inc. Device, system, and method for transcatheter treatment of valve regurgitation
US9155619B2 (en) 2011-02-25 2015-10-13 Edwards Lifesciences Corporation Prosthetic heart valve delivery apparatus
US8454656B2 (en) 2011-03-01 2013-06-04 Medtronic Ventor Technologies Ltd. Self-suturing anchors
US9072511B2 (en) 2011-03-25 2015-07-07 Kardium Inc. Medical kit for constricting tissue or a bodily orifice, for example, a mitral valve
US8845588B2 (en) 2011-04-19 2014-09-30 Medtronic Vascular, Inc. Sheath introducer system with exchangeable hemostatic valves
EP2520250B1 (en) 2011-05-04 2014-02-19 Medtentia International Ltd Oy Medical device for a cardiac valve implant
EP2709520A4 (en) 2011-05-17 2014-12-10 Landy Aaron Toth DEVICES, SYSTEMS AND METHOD FOR THE ASSESSMENT OF IMPLANTS, ORGANS, TRANSPLANTS, TISSUE, SYNTHETIC CONSTRUCTS, TUBULAR RAPPLANTS AND THE SAME
US8945209B2 (en) 2011-05-20 2015-02-03 Edwards Lifesciences Corporation Encapsulated heart valve
US8840664B2 (en) 2011-06-15 2014-09-23 Edwards Lifesciences Corporation Heart valve prosthesis anchoring device and methods
WO2012175483A1 (en) 2011-06-20 2012-12-27 Jacques Seguin Prosthetic leaflet assembly for repairing a defective cardiac valve and methods of using the same
CA2840084C (en) 2011-06-21 2019-11-05 Foundry Newco Xii, Inc. Prosthetic heart valve devices and associated systems and methods
US10792152B2 (en) 2011-06-23 2020-10-06 Valtech Cardio, Ltd. Closed band for percutaneous annuloplasty
US9918840B2 (en) 2011-06-23 2018-03-20 Valtech Cardio, Ltd. Closed band for percutaneous annuloplasty
US9364326B2 (en) 2011-06-29 2016-06-14 Mitralix Ltd. Heart valve repair devices and methods
US9629715B2 (en) 2011-07-28 2017-04-25 V-Wave Ltd. Devices for reducing left atrial pressure having biodegradable constriction, and methods of making and using same
EP2741711B1 (en) 2011-08-11 2018-05-30 Tendyne Holdings, Inc. Improvements for prosthetic valves and related inventions
US9343224B2 (en) 2011-08-19 2016-05-17 Leviticus Cardio Ltd. Coplanar energy transfer
US20130053792A1 (en) * 2011-08-24 2013-02-28 Ablative Solutions, Inc. Expandable catheter system for vessel wall injection and muscle and nerve fiber ablation
EP2755602B1 (en) 2011-09-12 2017-08-09 Highlife SAS Transcatheter valve prosthesis
US8956404B2 (en) 2011-09-12 2015-02-17 Highlife Sas Transcatheter valve prosthesis
US8900295B2 (en) 2011-09-26 2014-12-02 Edwards Lifesciences Corporation Prosthetic valve with ventricular tethers
US9763780B2 (en) 2011-10-19 2017-09-19 Twelve, Inc. Devices, systems and methods for heart valve replacement
US9655722B2 (en) 2011-10-19 2017-05-23 Twelve, Inc. Prosthetic heart valve devices, prosthetic mitral valves and associated systems and methods
US9039757B2 (en) 2011-10-19 2015-05-26 Twelve, Inc. Prosthetic heart valve devices, prosthetic mitral valves and associated systems and methods
EA201400481A1 (ru) 2011-10-19 2014-10-30 Твелв, Инк. Искусственные сердечно-клапанные устройства, искусственные митральные клапаны и соответствующие системы и способы
EP3970627B1 (en) 2011-11-08 2023-12-20 Edwards Lifesciences Innovation (Israel) Ltd. Controlled steering functionality for implant-delivery tool
EP2591754B1 (en) 2011-11-10 2015-02-25 Medtentia International Ltd Oy A device and a method for improving the function of a heart valve
EP2591755A1 (en) 2011-11-12 2013-05-15 Medtentia International Ltd Oy Device and method for improving fixation of a medical device
US20130123912A1 (en) 2011-11-15 2013-05-16 Boston Scientific Scimed, Inc. Medical device with nosecone and nosecone tube extension
US20140350669A1 (en) 2011-12-01 2014-11-27 The Trustees if The University of Pennsylvania Percutaneous valve replacement devices
WO2013086132A1 (en) 2011-12-06 2013-06-13 Aortic Innovations Llc Device for endovascular aortic repair and method of using the same
PL2787926T3 (pl) 2011-12-09 2022-11-14 Edwards Lifesciences Corporation Usprawnione wsporniki spojeń zastawki protetycznej serca
EP3581152B1 (en) 2011-12-21 2025-09-24 Majoro Cardiac Innovations, LLC Platforms for mitral valve replacement
US9078747B2 (en) 2011-12-21 2015-07-14 Edwards Lifesciences Corporation Anchoring device for replacing or repairing a heart valve
EP2620125B1 (en) 2012-01-24 2017-10-11 Medtentia International Ltd Oy An arrangement, a loop-shaped support, a prosthetic heart valve and a method of repairing or replacing a native heart valve
WO2013112547A1 (en) 2012-01-25 2013-08-01 Boston Scientific Scimed, Inc. Valve assembly with a bioabsorbable gasket and a replaceable valve implant
EP2809263B1 (en) 2012-01-31 2017-08-23 Mitral Valve Technologies Sàrl Mitral valve docking devices, systems
US20150094802A1 (en) 2012-02-28 2015-04-02 Mvalve Technologies Ltd. Single-ring cardiac valve support
US9579198B2 (en) 2012-03-01 2017-02-28 Twelve, Inc. Hydraulic delivery systems for prosthetic heart valve devices and associated methods
US20130274873A1 (en) 2012-03-22 2013-10-17 Symetis Sa Transcatheter Stent-Valves and Methods, Systems and Devices for Addressing Para-Valve Leakage
ES2535295T3 (es) 2012-03-23 2015-05-08 Sorin Group Italia S.R.L. Prótesis de válvula plegable
US9295547B2 (en) 2012-03-28 2016-03-29 Medtronic Vascular Galway Prosthesis for transcatheter valve implantation
US9999501B2 (en) 2012-04-18 2018-06-19 Medtronic CV Luxembourg S.a.r.l. Valve prosthesis
US9427315B2 (en) 2012-04-19 2016-08-30 Caisson Interventional, LLC Valve replacement systems and methods
US9011515B2 (en) 2012-04-19 2015-04-21 Caisson Interventional, LLC Heart valve assembly systems and methods
DE102012207053A1 (de) 2012-04-27 2013-10-31 Abiomed Europe Gmbh Intravasale rotationsblutpumpe
CA2872611C (en) 2012-05-16 2020-09-15 Edwards Lifesciences Corporation Systems and methods for placing a coapting member between valvular leaflets
CN104684505B (zh) 2012-05-20 2017-07-07 戴尔马修墨医学研究内结构和服务有限公司 人造二尖瓣
US20130331931A1 (en) 2012-06-07 2013-12-12 Boston Scientific Scimed Inc. Apparatus for Replacing a Native Heart Valve and Method of Making the Same
US9883941B2 (en) 2012-06-19 2018-02-06 Boston Scientific Scimed, Inc. Replacement heart valve
EP2740400A4 (en) 2012-06-22 2016-01-27 Olympus Corp BITE EAR AND MEDICAL INSTRUMENT
US20140005776A1 (en) 2012-06-29 2014-01-02 St. Jude Medical, Cardiology Division, Inc. Leaflet attachment for function in various shapes and sizes
US10376360B2 (en) 2012-07-27 2019-08-13 W. L. Gore & Associates, Inc. Multi-frame prosthetic valve apparatus and methods
WO2014022124A1 (en) 2012-07-28 2014-02-06 Tendyne Holdings, Inc. Improved multi-component designs for heart valve retrieval device, sealing structures and stent assembly
WO2014021905A1 (en) 2012-07-30 2014-02-06 Tendyne Holdings, Inc. Improved delivery systems and methods for transcatheter prosthetic valves
US8926690B2 (en) 2012-08-13 2015-01-06 Medtronic, Inc. Heart valve prosthesis
US10206775B2 (en) 2012-08-13 2019-02-19 Medtronic, Inc. Heart valve prosthesis
US9468525B2 (en) 2012-08-13 2016-10-18 Medtronic, Inc. Heart valve prosthesis
US9232995B2 (en) 2013-01-08 2016-01-12 Medtronic, Inc. Valve prosthesis and method for delivery
US9636481B2 (en) 2012-09-27 2017-05-02 Boston Scientific Scimed, Inc. Steerable catheter with brake assembly
GB2507053A (en) 2012-10-16 2014-04-23 Jonathan Featherstone Nephroureterectomy apparatus
US9226823B2 (en) 2012-10-23 2016-01-05 Medtronic, Inc. Valve prosthesis
WO2014064694A2 (en) 2012-10-23 2014-05-01 Valtech Cardio, Ltd. Controlled steering functionality for implant-delivery tool
US10376266B2 (en) 2012-10-23 2019-08-13 Valtech Cardio, Ltd. Percutaneous tissue anchor techniques
EP2730252A1 (en) 2012-11-07 2014-05-14 Medtentia International Ltd Oy Medical device for a cardiac valve implant, and a metod of manufacturing the medical device
DK3158975T3 (da) 2012-11-20 2023-03-13 Innovheart S R L Protesesystem til hjerteklaperstatning
WO2014087402A1 (en) 2012-12-06 2014-06-12 Valtech Cardio, Ltd. Techniques for guide-wire based advancement of a tool
US9737398B2 (en) 2012-12-19 2017-08-22 W. L. Gore & Associates, Inc. Prosthetic valves, frames and leaflets and methods thereof
US11406498B2 (en) 2012-12-20 2022-08-09 Philips Image Guided Therapy Corporation Implant delivery system and implants
US9949692B2 (en) 2012-12-21 2018-04-24 Canary Medical Inc. Stent graft monitoring assembly and method of use thereof
WO2014102268A1 (en) 2012-12-27 2014-07-03 Transcatheter Technologies Gmbh Apparatus and set for folding or unfolding a medical implant comprising a clamping mechanism, implant and method
US9066801B2 (en) 2013-01-08 2015-06-30 Medtronic, Inc. Valve prosthesis and method for delivery
US8986371B2 (en) 2013-01-08 2015-03-24 Medtronic CV Luxembourg S.a.r.l. Method of treating paravalvular leakage after prosthetic valve implantation
US20150351906A1 (en) 2013-01-24 2015-12-10 Mitraltech Ltd. Ventricularly-anchored prosthetic valves
JP6600558B2 (ja) 2013-01-25 2019-10-30 メドテンシア インターナショナル エルティーディー オーワイ 腱索及び／又は弁尖の収集のための装置、医療システム、及び方法
CA2897907A1 (en) 2013-01-25 2014-07-31 Medtentia International Ltd Oy Temporary atrium support device
KR20150140634A (ko) 2013-01-25 2015-12-16 메드텐티아 인터내셔날 엘티디 오와이 판륜성형술 임플란트의 선택을 용이하게 위한 의료 디바이스 및 방법
CN104994812B (zh) 2013-01-25 2017-05-17 梅德坦提亚国际有限公司 用于接管和/或临时或部分支撑心脏中的天然瓣膜的短时间置换的瓣膜及其递送方法
US10856983B2 (en) 2013-01-25 2020-12-08 Medtentia International Ltd. Oy System for cardiac valve repair
US10413401B2 (en) 2013-02-01 2019-09-17 Medtronic CV Luxembourg S.a.r.l. Anti-paravalvular leakage component for a transcatheter valve prosthesis
US9439763B2 (en) 2013-02-04 2016-09-13 Edwards Lifesciences Corporation Prosthetic valve for replacing mitral valve
US9168129B2 (en) 2013-02-12 2015-10-27 Edwards Lifesciences Corporation Artificial heart valve with scalloped frame design
US9844435B2 (en) 2013-03-01 2017-12-19 St. Jude Medical, Cardiology Division, Inc. Transapical mitral valve replacement
US10583002B2 (en) 2013-03-11 2020-03-10 Neovasc Tiara Inc. Prosthetic valve with anti-pivoting mechanism
US9119713B2 (en) 2013-03-11 2015-09-01 St. Jude Medical, Cardiology Division, Inc. Transcatheter valve replacement
US10507104B2 (en) 2013-03-14 2019-12-17 Suzhou Jiecheng Medical Technology Co., Ltd. Sutureless valve prosthesis delivery device and methods of use thereof
US11406497B2 (en) 2013-03-14 2022-08-09 Jc Medical, Inc. Heart valve prosthesis
US20140277427A1 (en) 2013-03-14 2014-09-18 Cardiaq Valve Technologies, Inc. Prosthesis for atraumatically grasping intralumenal tissue and methods of delivery
EP2967938B1 (en) 2013-03-14 2017-03-01 Medtronic Vascular Inc. Method for manufacturing a stent and stent manufactured thereby
US9173713B2 (en) 2013-03-14 2015-11-03 Hansen Medical, Inc. Torque-based catheter articulation
CN106691630A (zh) 2013-03-14 2017-05-24 斯波瑞申有限公司 瓣膜装载方法、系统和装置
US11259923B2 (en) 2013-03-14 2022-03-01 Jc Medical, Inc. Methods and devices for delivery of a prosthetic valve
US9289297B2 (en) 2013-03-15 2016-03-22 Cardiosolutions, Inc. Mitral valve spacer and system and method for implanting the same
CN105377192A (zh) 2013-05-09 2016-03-02 米塔埃瑟斯医疗有限公司 心脏瓣膜辅助修复体
EP3326583B1 (en) 2013-05-20 2018-12-12 Edwards Lifesciences Corporation Prosthetic heart valve delivery apparatus
EP2805695A1 (en) 2013-05-21 2014-11-26 Medtentia International Ltd Oy Medical system for annuloplasty
US9610159B2 (en) 2013-05-30 2017-04-04 Tendyne Holdings, Inc. Structural members for prosthetic mitral valves
CN105451688A (zh) 2013-06-14 2016-03-30 哈祖有限公司 用于治疗瓣膜反流的方法和装置
US20150005874A1 (en) 2013-06-27 2015-01-01 Tendyne Holdings, Inc. Atrial Thrombogenic Sealing Pockets for Prosthetic Mitral Valves
CN105358084B (zh) 2013-07-01 2018-11-09 波士顿科学国际有限公司 用于肾神经消融的医疗器械
US10028832B2 (en) 2013-07-10 2018-07-24 Medtronic, Inc. Helical coil mitral valve annuloplasty systems and methods
SG10202103500PA (en) 2013-08-12 2021-05-28 Mitral Valve Tech Sarl Apparatus and methods for implanting a replacement heart valve
US10052198B2 (en) 2013-08-14 2018-08-21 Mitral Valve Technologies Sarl Coiled anchor for supporting prosthetic heart valve, prosthetic heart valve, and deployment device
CA2920865C (en) 2013-08-14 2023-06-06 Mitral Valve Technologies Sarl Replacement heart valve apparatus and methods
US10195028B2 (en) 2013-09-10 2019-02-05 Edwards Lifesciences Corporation Magnetic retaining mechanisms for prosthetic valves
US9839511B2 (en) 2013-10-05 2017-12-12 Sino Medical Sciences Technology Inc. Device and method for mitral valve regurgitation treatment
US9662202B2 (en) 2013-10-24 2017-05-30 Medtronic, Inc. Heart valve prosthesis
US9889004B2 (en) 2013-11-19 2018-02-13 St. Jude Medical, Cardiology Division, Inc. Sealing structures for paravalvular leak protection
US9848880B2 (en) 2013-11-20 2017-12-26 James E. Coleman Adjustable heart valve implant
US10098734B2 (en) 2013-12-05 2018-10-16 Edwards Lifesciences Corporation Prosthetic heart valve and delivery apparatus
US9901444B2 (en) 2013-12-17 2018-02-27 Edwards Lifesciences Corporation Inverted valve structure
KR102432831B1 (ko) 2014-02-04 2022-08-12 이노브하르트 에세.에레.엘레. 심장 판막용 인공 디바이스
WO2015124631A2 (en) 2014-02-18 2015-08-27 Medtentia International Ltd Oy Medical device for a cardiac valve implant
EP2907479A1 (en) 2014-02-18 2015-08-19 Medtentia International Ltd Oy A system and a method for delivery of an annuloplasty implant
WO2015124630A1 (en) 2014-02-18 2015-08-27 Medtentia International Ltd Oy Stapling device
EP3107495B2 (en) 2014-02-18 2025-05-14 St. Jude Medical, Cardiology Division, Inc. Bowed runners and corresponding valve assemblies for paravalvular leak protection
CA3189691A1 (en) 2014-02-21 2015-08-27 Mitral Valve Technologies Sarl Devices, systems and methods for delivering a prosthetic mitral valve and anchoring device
CA2938614C (en) 2014-02-21 2024-01-23 Edwards Lifesciences Cardiaq Llc Delivery device for controlled deployement of a replacement valve
US10064719B2 (en) 2014-03-11 2018-09-04 Highlife Sas Transcatheter valve prosthesis
DE102014102650A1 (de) 2014-02-28 2015-09-03 Highlife Sas Transkatheter-Klappenprothese
US9763779B2 (en) 2014-03-11 2017-09-19 Highlife Sas Transcatheter valve prosthesis
US9889003B2 (en) 2014-03-11 2018-02-13 Highlife Sas Transcatheter valve prosthesis
CA2937566C (en) 2014-03-10 2023-09-05 Tendyne Holdings, Inc. Devices and methods for positioning and monitoring tether load for prosthetic mitral valve
US9687343B2 (en) 2014-03-11 2017-06-27 Highlife Sas Transcatheter valve prosthesis
EP3119351B1 (en) 2014-03-18 2021-10-20 St. Jude Medical, Cardiology Division, Inc. Mitral valve replacement toggle cell securement
EP2921140A1 (en) 2014-03-18 2015-09-23 St. Jude Medical, Cardiology Division, Inc. Percutaneous valve anchoring for a prosthetic aortic valve
JP6526043B2 (ja) 2014-03-26 2019-06-05 セント・ジュード・メディカル，カーディオロジー・ディヴィジョン，インコーポレイテッド 経カテーテル僧帽弁ステントフレーム
WO2015153755A2 (en) 2014-04-01 2015-10-08 Medtronic Inc. Anti-paravalvular leakage component for a transcatheter valve prosthesis
US10029037B2 (en) 2014-04-15 2018-07-24 Tc1 Llc Sensors for catheter pumps
EP3131503B1 (en) 2014-04-17 2019-06-12 Medtronic Vascular Galway Hinged transcatheter prosthetic heart valve delivery system
US10154904B2 (en) 2014-04-28 2018-12-18 Edwards Lifesciences Corporation Intravascular introducer devices
US10195025B2 (en) 2014-05-12 2019-02-05 Edwards Lifesciences Corporation Prosthetic heart valve
USRE49792E1 (en) 2014-05-14 2024-01-09 Corcym S.R.L. Implant device and implantation kit
US20150328000A1 (en) 2014-05-19 2015-11-19 Cardiaq Valve Technologies, Inc. Replacement mitral valve with annular flap
US9532870B2 (en) 2014-06-06 2017-01-03 Edwards Lifesciences Corporation Prosthetic valve for replacing a mitral valve
US10111749B2 (en) 2014-06-11 2018-10-30 Medtronic Vascular, Inc. Prosthetic valve with flow director
US9974647B2 (en) 2014-06-12 2018-05-22 Caisson Interventional, LLC Two stage anchor and mitral valve assembly
EP3157469B2 (en) 2014-06-18 2024-10-02 Polares Medical Inc. Mitral valve implants for the treatment of valvular regurgitation
GB2527747A (en) 2014-06-19 2016-01-06 Neosurgical Ltd Laparoscopic surgical device
US9700412B2 (en) 2014-06-26 2017-07-11 Mitralix Ltd. Heart valve repair devices for placement in ventricle and delivery systems for implanting heart valve repair devices
CN104055604B (zh) 2014-07-07 2016-06-01 宁波健世生物科技有限公司 一种带锚定装置的心脏瓣膜植入器械
US9180005B1 (en) 2014-07-17 2015-11-10 Millipede, Inc. Adjustable endolumenal mitral valve ring
US10058424B2 (en) 2014-08-21 2018-08-28 Edwards Lifesciences Corporation Dual-flange prosthetic valve frame
WO2016036774A1 (en) 2014-09-01 2016-03-10 Clph, Llc Steerable catheters and methods for making them
JP2017527373A (ja) 2014-09-08 2017-09-21 メドテンティア・インターナショナル・リミテッド・オサケユキチュアＭｅｄｔｅｎｔｉａ Ｉｎｔｅｒｎａｔｉｏｎａｌ Ｌｔｄ Ｏｙ 弁輪形成インプラント
US10016272B2 (en) 2014-09-12 2018-07-10 Mitral Valve Technologies Sarl Mitral repair and replacement devices and methods
US10576249B2 (en) 2014-09-30 2020-03-03 St. Jude Medical Cardiology Division, Inc. Medical device including an actuator restraining assembly
EP3138465A4 (en) 2014-10-01 2018-01-03 Olympus Corporation Endoscope bending tube and endoscope provided with endoscope bending tube
WO2016061139A1 (en) 2014-10-13 2016-04-21 Hlt, Inc. Inversion delivery device and method for a prosthesis
FR3027212A1 (fr) 2014-10-16 2016-04-22 Seguin Jacques Implant intervalvulaire pour valve mitrale
US9750605B2 (en) 2014-10-23 2017-09-05 Caisson Interventional, LLC Systems and methods for heart valve therapy
CN104298404B (zh) 2014-10-28 2017-05-31 上海天马微电子有限公司 阵列基板及其制作方法、显示装置及其驱动方法
US10213307B2 (en) 2014-11-05 2019-02-26 Medtronic Vascular, Inc. Transcatheter valve prosthesis having an external skirt for sealing and preventing paravalvular leakage
US9788893B2 (en) 2014-11-20 2017-10-17 Biosense Webster (Israel) Ltd. Catheter with soft distal tip for mapping and ablating tubular region
US9901445B2 (en) 2014-11-21 2018-02-27 Boston Scientific Scimed, Inc. Valve locking mechanism
US9693860B2 (en) 2014-12-01 2017-07-04 Medtronic, Inc. Segmented transcatheter valve prosthesis having an unsupported valve segment
CN106999178B (zh) 2014-12-02 2019-12-24 4科技有限公司 偏心组织锚定器
WO2016093877A1 (en) 2014-12-09 2016-06-16 Cephea Valve Technologies, Inc. Replacement cardiac valves and methods of use and manufacture
EP3037064B1 (en) 2014-12-23 2018-03-14 Venus MedTech (HangZhou), Inc. Minimally invasive mitral valve replacement with brim
EP3244809B1 (en) 2014-12-19 2020-02-05 Paradox Medical Implantable intracardiac device
CN107427364B (zh) 2014-12-19 2019-12-10 杭州启明医疗器械股份有限公司 具有边沿的微创二尖瓣瓣膜置换
US10188833B2 (en) 2015-01-21 2019-01-29 Medtronic Vascular, Inc. Guide catheter with steering mechanisms
EP3141179A4 (en) 2015-01-21 2018-01-10 Olympus Corporation Endoscope insertion part and endoscope
US10039637B2 (en) 2015-02-11 2018-08-07 Edwards Lifesciences Corporation Heart valve docking devices and implanting methods
JP6735294B2 (ja) 2015-02-13 2020-08-05 ボストン サイエンティフィック サイムド，インコーポレイテッドＢｏｓｔｏｎ Ｓｃｉｅｎｔｉｆｉｃ Ｓｃｉｍｅｄ，Ｉｎｃ． インプラント可能な心臓弁装置
EP4706567A2 (en) 2015-03-05 2026-03-11 Ancora Heart, Inc. Devices of visualizing and determining depth of penetration in cardiac tissue
CA2979817C (en) 2015-03-18 2023-03-28 Mitralign, Inc. Tissue anchors and percutaneous tricuspid valve repair using a tissue anchor
EP3273910B1 (en) 2015-03-24 2024-12-18 St. Jude Medical, Cardiology Division, Inc. Mitral heart valve replacement
CN107949351A (zh) 2015-03-30 2018-04-20 伊诺佩斯生物医药有限公司 用于血管内装置的天线
EP3078350B1 (en) 2015-04-09 2018-01-31 Frid Mind Technologies 3d filter for prevention of stroke
US10368986B2 (en) 2015-04-15 2019-08-06 Medtronic, Inc. Transcatheter prosthetic heart valve delivery system and method
US10064718B2 (en) 2015-04-16 2018-09-04 Edwards Lifesciences Corporation Low-profile prosthetic heart valve for replacing a mitral valve
US10441416B2 (en) 2015-04-21 2019-10-15 Edwards Lifesciences Corporation Percutaneous mitral valve replacement device
EP3087952A1 (en) 2015-04-29 2016-11-02 Kephalios S.A.S. An annuloplasty system and a method for monitoring the effectiveness of an annuloplasty treatment
US10376363B2 (en) 2015-04-30 2019-08-13 Edwards Lifesciences Cardiaq Llc Replacement mitral valve, delivery system for replacement mitral valve and methods of use
EP3288496B1 (en) 2015-04-30 2024-05-29 Edwards Lifesciences Innovation (Israel) Ltd. Annuloplasty technologies
US9629720B2 (en) 2015-05-04 2017-04-25 Jacques Seguin Apparatus and methods for treating cardiac valve regurgitation
ES3001450T3 (en) 2015-05-14 2025-03-05 Edwards Lifesciences Corp Heart valve sealing devices and delivery devices therefor
WO2016183523A1 (en) 2015-05-14 2016-11-17 Cephea Valve Technologies, Inc. Cardiac valve delivery devices and systems
WO2016183526A1 (en) 2015-05-14 2016-11-17 Cephea Valve Technologies, Inc. Replacement mitral valves
US10028733B2 (en) 2015-05-28 2018-07-24 National University Of Ireland, Galway Fistula treatment device
EP3307207A1 (en) 2015-06-12 2018-04-18 St. Jude Medical, Cardiology Division, Inc. Heart valve repair and replacement
US10092400B2 (en) 2015-06-23 2018-10-09 Edwards Lifesciences Cardiaq Llc Systems and methods for anchoring and sealing a prosthetic heart valve
US10335277B2 (en) 2015-07-02 2019-07-02 Boston Scientific Scimed Inc. Adjustable nosecone
US9974650B2 (en) 2015-07-14 2018-05-22 Edwards Lifesciences Corporation Prosthetic heart valve
US9895222B2 (en) 2015-08-17 2018-02-20 Venus Medtech (Hangzhou) Inc. Aortic replacement valve
US10631977B2 (en) 2015-08-24 2020-04-28 Edwards Lifesciences Corporation Covering and assembly method for transcatheter valve
US10575951B2 (en) 2015-08-26 2020-03-03 Edwards Lifesciences Cardiaq Llc Delivery device and methods of use for transapical delivery of replacement mitral valve
US10117744B2 (en) 2015-08-26 2018-11-06 Edwards Lifesciences Cardiaq Llc Replacement heart valves and methods of delivery
US10034747B2 (en) 2015-08-27 2018-07-31 Medtronic Vascular, Inc. Prosthetic valve system having a docking component and a prosthetic valve component
US10350066B2 (en) 2015-08-28 2019-07-16 Edwards Lifesciences Cardiaq Llc Steerable delivery system for replacement mitral valve and methods of use
CA2995855C (en) 2015-09-02 2024-01-30 Edwards Lifesciences Corporation Spacer for securing a transcatheter valve to a bioprosthetic cardiac structure
US10080653B2 (en) 2015-09-10 2018-09-25 Edwards Lifesciences Corporation Limited expansion heart valve
US10327894B2 (en) 2015-09-18 2019-06-25 Tendyne Holdings, Inc. Methods for delivery of prosthetic mitral valves
US10350067B2 (en) 2015-10-26 2019-07-16 Edwards Lifesciences Corporation Implant delivery capsule
CN108992210B (zh) 2015-11-06 2021-08-27 麦克尔有限公司 二尖瓣假体
WO2017087424A1 (en) 2015-11-17 2017-05-26 Millipede, Inc. Implantable device and delivery system for reshaping a heart valve annulus
FR3043907A1 (fr) 2015-11-23 2017-05-26 Alain Dibie Assemblage pour le remplacement de la valve atrio-ventriculaire tricuspide
US10265169B2 (en) 2015-11-23 2019-04-23 Edwards Lifesciences Corporation Apparatus for controlled heart valve delivery
US11033387B2 (en) 2015-11-23 2021-06-15 Edwards Lifesciences Corporation Methods for controlled heart valve delivery
US10357351B2 (en) 2015-12-04 2019-07-23 Edwards Lifesciences Corporation Storage assembly for prosthetic valve
CN105581858B (zh) 2015-12-15 2018-04-10 先健科技(深圳)有限公司 人工心脏瓣膜支架及人工心脏瓣膜
US10905555B2 (en) 2015-12-22 2021-02-02 Medtentia International Ltd Oy Medical securing device for securing a cardiac implant device with a securing member
EP3818963B1 (en) 2015-12-30 2025-08-27 Caisson Interventional, LLC Systems for heart valve therapy
CN105496606A (zh) 2016-01-11 2016-04-20 北京迈迪顶峰医疗科技有限公司 一种经导管输送主动脉瓣瓣膜装置
US11833034B2 (en) 2016-01-13 2023-12-05 Shifamed Holdings, Llc Prosthetic cardiac valve devices, systems, and methods
CN108882978B (zh) 2016-01-22 2020-11-06 梅德坦提亚国际有限公司 瓣膜成形术植入物
EP3410984B1 (en) 2016-02-04 2023-03-29 Boston Scientific Scimed, Inc. Mitral valve inversion prostheses
US10363130B2 (en) 2016-02-05 2019-07-30 Edwards Lifesciences Corporation Devices and systems for docking a heart valve
CN114392007A (zh) 2016-03-01 2022-04-26 米特拉尔爱有限责任公司 用于锚固和/或密封心脏瓣膜假体的系统、装置和方法
US10667904B2 (en) 2016-03-08 2020-06-02 Edwards Lifesciences Corporation Valve implant with integrated sensor and transmitter
EP3426195A4 (en) 2016-03-08 2019-11-20 Dura LLC VALVE BLADE REPLACEMENT SYSTEM AND ASSOCIATED METHOD
WO2019241777A1 (en) 2018-06-15 2019-12-19 Dura Llc Heart valve leaflet replacement device and multi-stage, multi-lumen heart valve delivery system and method for the same
WO2017160823A1 (en) 2016-03-14 2017-09-21 Medtronic Vascular Inc. Stented prosthetic heart valve having a wrap and delivery devices
EP3434312B1 (en) 2016-03-22 2020-09-09 Terumo Kabushiki Kaisha Long body for medical use
USD815744S1 (en) 2016-04-28 2018-04-17 Edwards Lifesciences Cardiaq Llc Valve frame for a delivery system
WO2017196909A1 (en) 2016-05-12 2017-11-16 St. Jude Medical, Cardiology Division, Inc. Mitral heart valve replacement
US10201416B2 (en) 2016-05-16 2019-02-12 Boston Scientific Scimed, Inc. Replacement heart valve implant with invertible leaflets
US10456245B2 (en) 2016-05-16 2019-10-29 Edwards Lifesciences Corporation System and method for applying material to a stent
WO2017214098A1 (en) 2016-06-06 2017-12-14 Medtronic Vascular Inc. Transcatheter prosthetic heart valve delivery system with lateral offset control
WO2018013725A1 (en) 2016-07-12 2018-01-18 Graftworx, Inc. System and method for measuring blood flow parameters in a blood vessel having an endovascular prosthesis
US11185413B2 (en) 2016-07-13 2021-11-30 Medfree, Inc. Tissue grasping devices and related methods
US10716916B2 (en) * 2016-07-21 2020-07-21 Creganna Unlimited Company High load steerable shaft and method for cardiac catheter
US10350062B2 (en) 2016-07-21 2019-07-16 Edwards Lifesciences Corporation Replacement heart valve prosthesis
US11304698B2 (en) 2016-07-25 2022-04-19 Virender K. Sharma Cardiac shunt device and delivery system
US20180028784A1 (en) 2016-07-28 2018-02-01 Cook Medical Technolgoies Llc Control wire distal securement in steerable catheter
WO2018025260A1 (en) 2016-07-31 2018-02-08 Mvalve Technologies Ltd. Intracardiac devices comprising wire-supported valve leaflets
WO2018026904A1 (en) 2016-08-03 2018-02-08 Spence Paul A Devices, systems and methods to improve placement and prevent heart block with percutaneous aortic valve replacement
EP3284413B1 (en) 2016-08-16 2019-12-18 Medtentia International Ltd Oy Medical securing device for securing a cardiac implant device with a securing member
US10646340B2 (en) 2016-08-19 2020-05-12 Edwards Lifesciences Corporation Steerable delivery system for replacement mitral valve
CR20190069A (es) 2016-08-26 2019-05-14 Edwards Lifesciences Corp Valvulas y sistemas de acoplamiento de valvulas corazon
US10722359B2 (en) * 2016-08-26 2020-07-28 Edwards Lifesciences Corporation Heart valve docking devices and systems
CN114569289A (zh) 2016-08-26 2022-06-03 爱德华兹生命科学公司 多部分置换心脏瓣膜假体
CN109890326B (zh) 2016-10-26 2026-04-03 美敦力瓦斯科尔勒公司 具有瓣周密封包裹部的带支架的假体心脏瓣膜
US10758348B2 (en) 2016-11-02 2020-09-01 Edwards Lifesciences Corporation Supra and sub-annular mitral valve delivery system
US9999502B2 (en) 2016-11-04 2018-06-19 Highlife Sas Transcather valve prosthesis
US10456247B2 (en) 2016-11-04 2019-10-29 Highlife Sas Transcatheter valve prosthesis
US10188514B2 (en) 2016-11-04 2019-01-29 Highlife Sas Transcatheter valve prosthesis
US10195027B2 (en) 2016-11-04 2019-02-05 Highlife Sas Transcatheter valve prosthesis
US11376121B2 (en) 2016-11-04 2022-07-05 Highlife Sas Transcatheter valve prosthesis
US10463484B2 (en) 2016-11-17 2019-11-05 Edwards Lifesciences Corporation Prosthetic heart valve having leaflet inflow below frame
US10973631B2 (en) 2016-11-17 2021-04-13 Edwards Lifesciences Corporation Crimping accessory device for a prosthetic valve
AU2017363069B2 (en) 2016-11-18 2020-08-20 Cephea Valve Technologies, Inc. Cardiac valve delivery devices and systems
US10603165B2 (en) 2016-12-06 2020-03-31 Edwards Lifesciences Corporation Mechanically expanding heart valve and delivery apparatus therefor
FR3060292B1 (fr) 2016-12-15 2019-01-25 Cmi'nov Dispositif pour realiser ou preparer une annuloplastie mitrale par voie transfemorale
SG10202109534TA (en) * 2016-12-20 2021-10-28 Edwards Lifesciences Corp Systems and mechanisms for deploying a docking device for a replacement heart valve
US10813749B2 (en) 2016-12-20 2020-10-27 Edwards Lifesciences Corporation Docking device made with 3D woven fabric
JP2020501842A (ja) 2016-12-22 2020-01-23 ハート・リペアー・テクノロジーズ・インコーポレーテッド インプラントを心臓弁輪に固定する経皮的送達システム
EP3342355B1 (en) 2016-12-29 2020-04-22 Medtentia International Ltd Oy Medical securing device for securing an object with a securing member
US9877833B1 (en) 2016-12-30 2018-01-30 Pipeline Medical Technologies, Inc. Method and apparatus for transvascular implantation of neo chordae tendinae
US11696828B2 (en) 2016-12-30 2023-07-11 Pipeline Medical Technologies, Inc. Method and apparatus for mitral valve chord repair
US11083580B2 (en) 2016-12-30 2021-08-10 Pipeline Medical Technologies, Inc. Method of securing a leaflet anchor to a mitral valve leaflet
US10912919B2 (en) 2017-01-23 2021-02-09 Edwards Lifesciences Corporation Expandable sheath
AU2018203053B2 (en) 2017-01-23 2020-03-05 Cephea Valve Technologies, Inc. Replacement mitral valves
US10743991B2 (en) 2017-01-23 2020-08-18 Edwards Lifesciences Corporation Chordae tendineae adjustment
US11013600B2 (en) 2017-01-23 2021-05-25 Edwards Lifesciences Corporation Covered prosthetic heart valve
CA3051272C (en) 2017-01-23 2023-08-22 Cephea Valve Technologies, Inc. Replacement mitral valves
US11185406B2 (en) 2017-01-23 2021-11-30 Edwards Lifesciences Corporation Covered prosthetic heart valve
US11654023B2 (en) 2017-01-23 2023-05-23 Edwards Lifesciences Corporation Covered prosthetic heart valve
US10905550B2 (en) 2017-02-01 2021-02-02 Medtronic Vascular, Inc. Heart valve prostheses including torque anchoring mechanisms and delivery devices for the heart valve prostheses
US10675017B2 (en) 2017-02-07 2020-06-09 Edwards Lifesciences Corporation Transcatheter heart valve leaflet plication
CN110381887B (zh) 2017-02-10 2022-03-29 波士顿科学国际有限公司 用于重塑心脏瓣膜环的可植入装置和输送系统
US12201517B2 (en) 2017-02-17 2025-01-21 Cardiovascular Diagnostics Inc. Transcatheter heart valve apparatus for calcific mitral stenosis
EP3585312A4 (en) 2017-02-27 2020-12-02 Dura LLC NEW TRANSCATHETER VALVE REPLACEMENT DEVICE
WO2018165064A1 (en) 2017-03-06 2018-09-13 Boston Scientific Scimed, Inc. Replacement heart valve system having docking station with sacrificial valve
CN114587711A (zh) 2017-03-13 2022-06-07 宝来瑞斯医疗有限公司 用于经导管治疗瓣膜返流的装置、系统和方法
US10478303B2 (en) 2017-03-13 2019-11-19 Polares Medical Inc. Device, system, and method for transcatheter treatment of valvular regurgitation
US10653524B2 (en) 2017-03-13 2020-05-19 Polares Medical Inc. Device, system, and method for transcatheter treatment of valvular regurgitation
CN113081391A (zh) 2017-03-22 2021-07-09 爱德华兹生命科学公司 用于将生物假体装置植入和固定到湿组织的系统和方法
US20210113332A1 (en) 2017-03-27 2021-04-22 Truleaf Medical Ltd. Invertible valve support frame for use with prosthetic heart valve apparatus
WO2018178966A1 (en) 2017-03-27 2018-10-04 Truleaf Medical Ltd. Docking elements
US11318018B2 (en) 2017-03-28 2022-05-03 Cardiac Success Ltd. Method of improving cardiac function
CA3058150A1 (en) 2017-03-28 2018-10-04 Cardiac Success Ltd. Devices for delivering a band to encircle a plurality of papillary muscles in the heart
CN110520079B (zh) 2017-03-28 2022-09-27 美敦力公司 实现经导管的带支架的假体的压缩的张力构件引导设计
US11123187B2 (en) 2017-04-05 2021-09-21 Opus Medical Therapies, LLC Transcatheter atrial anchors and methods of implantation
US10716668B2 (en) 2017-04-05 2020-07-21 Medtronic, Inc. Delivery system with anchoring nosecone and method of delivery
CA3178029A1 (en) 2017-04-05 2018-10-11 Opus Medical Therapies, LLC Transcatheter atrial sealing skirt, anchor, and tether and methods of implantation
US11337685B2 (en) 2017-04-05 2022-05-24 Opus Medical Therapies, LLC Transcatheter anchoring assembly for a mitral valve, a mitral valve, and related methods
US11103351B2 (en) 2017-04-05 2021-08-31 Opus Medical Therapies, LLC Transcatheter atrial sealing skirt and related method
US10820992B2 (en) 2017-04-05 2020-11-03 Opus Medical Therapies, LLC Transcatheter atrial sealing skirt, anchor, and tether and methods of implantation
US10765515B2 (en) 2017-04-06 2020-09-08 University Of Maryland, Baltimore Distal anchor apparatus and methods for mitral valve repair
CN106890035A (zh) 2017-04-17 2017-06-27 乐普（北京）医疗器械股份有限公司 一种经导管植入式主动脉瓣膜装置
US10702378B2 (en) 2017-04-18 2020-07-07 Twelve, Inc. Prosthetic heart valve device and associated systems and methods
US10433961B2 (en) 2017-04-18 2019-10-08 Twelve, Inc. Delivery systems with tethers for prosthetic heart valve devices and associated methods
EP3395296B1 (en) 2017-04-28 2019-12-18 Medtentia International Ltd Oy Annuloplasty implant
US11135056B2 (en) 2017-05-15 2021-10-05 Edwards Lifesciences Corporation Devices and methods of commissure formation for prosthetic heart valve
EP3406225B1 (en) 2017-05-23 2023-04-26 HVR Cardio Oy Annuloplasty implant
US12064341B2 (en) 2017-05-31 2024-08-20 Edwards Lifesciences Corporation Sealing member for prosthetic heart valve
IL309520B2 (en) 2017-05-31 2026-02-01 Edwards Lifesciences Corp Sealing component for heart valve bushing
US10646338B2 (en) 2017-06-02 2020-05-12 Twelve, Inc. Delivery systems with telescoping capsules for deploying prosthetic heart valve devices and associated methods
US10952842B2 (en) 2017-06-07 2021-03-23 W. L. Gore & Associates, Inc. Prosthetic valve with improved washout
EP3417831B2 (en) 2017-06-19 2023-05-24 HVR Cardio Oy Delivery device for an annuloplasty implant
EP3417832A1 (en) 2017-06-22 2018-12-26 Medtentia International Ltd Oy Medical securing device for securing an object with a securing member
US11202643B2 (en) 2017-06-22 2021-12-21 Smith & Nephew, Inc. Anchor delivery system
SG11201912180QA (en) 2017-06-30 2020-01-30 Edwards Lifesciences Corp Docking stations transcatheter valves
AU2018294423B2 (en) 2017-06-30 2023-11-09 Lakshmi Prasad Dasi Prosthetic heart valve with tri-leaflet design for use in percutaneous valve replacement procedures
JP7134229B2 (ja) 2017-07-06 2022-09-09 ラグビア バスデ， 組織把持デバイスおよび関連方法
US10729541B2 (en) 2017-07-06 2020-08-04 Twelve, Inc. Prosthetic heart valve devices and associated systems and methods
EP3648708A4 (en) 2017-07-06 2021-03-31 Edwards Lifesciences Corporation CONTROLLED DISPENSING SYSTEM AND COMPONENTS
US10888421B2 (en) 2017-09-19 2021-01-12 Cardiovalve Ltd. Prosthetic heart valve with pouch
US11083575B2 (en) 2017-08-14 2021-08-10 Edwards Lifesciences Corporation Heart valve frame design with non-uniform struts
US10932903B2 (en) 2017-08-15 2021-03-02 Edwards Lifesciences Corporation Skirt assembly for implantable prosthetic valve
WO2019036548A2 (en) 2017-08-17 2019-02-21 Boston Scientific Scimed, Inc. Anchor delivery system and methods for valve repair
US10898319B2 (en) 2017-08-17 2021-01-26 Edwards Lifesciences Corporation Sealing member for prosthetic heart valve
US10973628B2 (en) 2017-08-18 2021-04-13 Edwards Lifesciences Corporation Pericardial sealing member for prosthetic heart valve
US10856971B2 (en) 2017-08-18 2020-12-08 Edwards Lifesciences Corporation Sealing members for prosthetic heart valve
US10722353B2 (en) 2017-08-21 2020-07-28 Edwards Lifesciences Corporation Sealing member for prosthetic heart valve
US10722351B2 (en) 2017-08-24 2020-07-28 Medtronic Vascular, Inc. Transcatheter prosthesis with sealing component, and systems and methods for delivering and deployment thereof
EP3672525A1 (en) 2017-08-24 2020-07-01 Medtronic Vascular Inc. Transseptal delivery systems having a deflecting segment and methods of use
CN111263622A (zh) 2017-08-25 2020-06-09 内奥瓦斯克迪亚拉公司 顺序展开的经导管二尖瓣假体
US11083572B2 (en) 2017-08-31 2021-08-10 Half Moon Medical, Inc. Prosthetic leaflet device
US11051939B2 (en) 2017-08-31 2021-07-06 Edwards Lifesciences Corporation Active introducer sheath system
US10973629B2 (en) 2017-09-06 2021-04-13 Edwards Lifesciences Corporation Sealing member for prosthetic heart valve
US11147667B2 (en) 2017-09-08 2021-10-19 Edwards Lifesciences Corporation Sealing member for prosthetic heart valve
CN109498213A (zh) 2017-09-14 2019-03-22 上海微创心通医疗科技有限公司 一种瓣膜支架和瓣膜假体
EP3456377B1 (en) 2017-09-14 2023-04-26 Sorin CRM SAS Attachment means for implantable cardiac device
CN111132636B (zh) 2017-09-27 2022-04-08 W.L.戈尔及同仁股份有限公司 带有可扩张框架的假体瓣膜以及相关系统和方法
CN109567985A (zh) 2017-09-29 2019-04-05 上海微创心通医疗科技有限公司 心脏瓣膜假体
WO2019081777A1 (en) 2017-10-27 2019-05-02 Medtentia International Ltd Oy IMPLANT OF ANNULOPLASTY
EP3476366B1 (en) 2017-10-27 2020-12-16 Medtentia International Ltd Oy Annuloplasty implant
CN120770981A (zh) 2017-10-30 2025-10-14 安多拉米诺科学公司 用于防渗漏血管内假体的可扩张密封裙部技术
US10835221B2 (en) 2017-11-02 2020-11-17 Valtech Cardio, Ltd. Implant-cinching devices and systems
US10806574B2 (en) 2017-11-20 2020-10-20 Medtronic Vascular, Inc. Delivery systems having a temporary valve and methods of use
US20200383679A1 (en) 2017-11-27 2020-12-10 T.A.G. Medical Devices - Agriculture Cooperative Ltd. Multiple anchor delivery system and method
WO2019108765A1 (en) 2017-11-29 2019-06-06 Medtronic, Inc. Tissue conduction communication using ramped drive signal
CN111479531B (zh) 2017-11-30 2022-11-04 波士顿科学国际有限公司 用于瓣膜修复的连接的锚固件输送系统和方法
JP7480944B2 (ja) 2017-12-11 2024-05-10 カリフォルニア インスティテュート オブ テクノロジー 血管内埋込可能補綴弁の製造に関するシステム、デバイス、および方法
GB201720803D0 (en) 2017-12-13 2018-01-24 Mitraltech Ltd Prosthetic Valve and delivery tool therefor
WO2019126794A1 (en) 2017-12-22 2019-06-27 Poly-Med, Inc. Tubular implants with controlled biodegradation
US20210052384A1 (en) 2018-01-05 2021-02-25 Medtentia International Ltd Oy A medical fastening device
CN110013359A (zh) 2018-01-07 2019-07-16 苏州杰成医疗科技有限公司 心脏瓣膜假体和制造膜的方法
US10980635B2 (en) 2018-01-07 2021-04-20 William Joseph Drasler Annuloplasty device and methods
CN110013353B (zh) 2018-01-07 2023-06-23 苏州杰成医疗科技有限公司 假体心脏瓣膜输送系统
US11547563B2 (en) 2018-01-08 2023-01-10 Medtentia International Ltd. Oy Annuloplasty device
IL276116B2 (en) 2018-01-19 2025-03-01 Edwards Lifesciences Corp Wrapped artificial heart valve
EP3720390B1 (en) 2018-01-25 2024-05-01 Edwards Lifesciences Corporation Delivery system for aided replacement valve recapture and repositioning post- deployment
WO2019147504A1 (en) 2018-01-25 2019-08-01 Cephea Valve Technologies, Inc. Cardiac valve delivery devices and systems
CN108125732A (zh) 2018-02-06 2018-06-08 北京迈迪顶峰医疗科技有限公司 人工瓣膜及人工瓣膜装置
EP3749253B1 (en) 2018-02-09 2023-07-05 The Provost, Fellows, Foundation Scholars, and the other members of Board, of the College of the Holy & Undiv. Trinity of Queen Elizabeth near Dublin A heart valve therapeutic device
CN111787885B (zh) 2018-02-22 2024-08-02 美敦力瓦斯科尔勒公司 假体心脏瓣膜递送系统和方法
US11051934B2 (en) 2018-02-28 2021-07-06 Edwards Lifesciences Corporation Prosthetic mitral valve with improved anchors and seal
WO2019195860A2 (en) 2018-04-04 2019-10-10 Vdyne, Llc Devices and methods for anchoring transcatheter heart valve
EP3784174B8 (en) 2018-04-24 2024-12-11 Caisson Interventional, LLC Systems for heart valve therapy
US11318011B2 (en) 2018-04-27 2022-05-03 Edwards Lifesciences Corporation Mechanically expandable heart valve with leaflet clamps
CN112423709A (zh) 2018-05-18 2021-02-26 万能医药公司 心脏瓣膜修复的方法和装置
US11234818B2 (en) 2018-05-21 2022-02-01 Medtentia International Ltd Oy Annuloplasty device
US11083571B2 (en) 2018-06-27 2021-08-10 Edwards Lifesciences Corporation Frame for prosthetic heart valve
WO2020018630A1 (en) 2018-07-18 2020-01-23 Millipede, Inc. Deployment restraint and delivery system for implantable cardiac device
US12290456B2 (en) 2018-08-21 2025-05-06 Shifamed Holdings, Llc Prosthetic cardiac valve devices, systems, and methods
US12161551B2 (en) 2018-08-30 2024-12-10 Edwards Lifesciences Corporation Systems and methods for sizing and implanting prosthetic heart valves
CA3109649A1 (en) 2018-09-06 2020-03-12 Edwards Lifesciences Corporation Pre-shaped tissue anchors and needles for tissue anchor deployment
WO2020051591A1 (en) 2018-09-07 2020-03-12 Icahn School Of Medicine At Mount Sinai Heart valve delivery system and method with rotational alignment
US20200060820A1 (en) 2018-09-20 2020-02-27 Mitralix Ltd. Systems and methods for positioning medical devices relative to heart valve anatomy
US11413146B2 (en) 2018-10-03 2022-08-16 Edwards Lifesciences Corporation Spring and coil devices for papillary muscle approximation and ventricle remodeling
US11413147B2 (en) 2018-10-03 2022-08-16 Edwards Lifesciences Corporation Ventricular remodeling using coil devices
EP3860519A4 (en) 2018-10-05 2022-07-06 Shifamed Holdings, LLC HEART VALVE PROSTHESIS, SYSTEMS AND PROCEDURES
US12232955B2 (en) 2018-10-06 2025-02-25 The Foundry Modular valve replacement systems and associated devices and methods of use
US11686043B2 (en) 2018-11-05 2023-06-27 Acclarent, Inc. Pull wire with coated fibers
US11583401B2 (en) 2018-12-13 2023-02-21 Medtronic Vascular, Inc. Heart valve repair
WO2020157018A1 (en) 2019-01-28 2020-08-06 Tricares SAS Three part stent second generation
JP7480161B2 (ja) 2019-02-08 2024-05-09 エドワーズ ライフサイエンシーズ コーポレイション 直接的心臓圧力監視
EP3923869A4 (en) 2019-02-11 2022-11-09 Heart Repair Technologies, Inc. PERCUTANEOUS DELIVERY SYSTEMS FOR ANCHORING AN IMPLANT IN A HEART VALVE RING
JP7541023B2 (ja) 2019-03-04 2024-08-27 エドワーズ ライフサイエンシーズ コーポレイション 人工弁のための交連部取付
WO2020191216A1 (en) 2019-03-19 2020-09-24 Shifamed Holdings, Llc Prosthetic cardiac valve devices, systems, and methods
US11602429B2 (en) 2019-04-01 2023-03-14 Neovasc Tiara Inc. Controllably deployable prosthetic valve
WO2020210652A1 (en) 2019-04-10 2020-10-15 Neovasc Tiara Inc. Prosthetic valve with natural blood flow
US20220054261A1 (en) 2019-04-12 2022-02-24 Shifamed Holdings, Llc Minimal frame prosthetic cardiac valve delivery devices, systems, and methods
WO2020236830A1 (en) 2019-05-20 2020-11-26 Caisson Interventional, LLC Systems and methods for heart valve therapy
CA3140397A1 (en) 2019-06-07 2020-12-10 Edwards Lifesciences Corporation Systems, devices, and methods for treating heart valves
EP4480454A3 (en) 2019-07-31 2025-07-09 St. Jude Medical, Cardiology Division, Inc. Alternate stent caf design for tavr
CN114502103B (zh) 2019-08-14 2025-12-12 因诺韦尔弗生物医疗有限公司 房室瓣置换
EP4013353B1 (en) 2019-08-16 2023-09-27 Medtronic Vascular, Inc. Heart valve repair
EP4203860A4 (en) 2020-08-31 2024-10-09 Shifamed Holdings, LLC PROSTHETIC IMPLANT DELIVERY SYSTEM
US20230320850A1 (en) 2020-08-31 2023-10-12 Shifamed Holdings, Llc Access sheath for prosthetic cardiac valve delivery systems
WO2022047274A1 (en) 2020-08-31 2022-03-03 Shifamed Holdings, Llc Prosthetic cardiac valve delivery systems and methods
WO2022047095A1 (en) 2020-08-31 2022-03-03 Shifamed Holdings, Llc Anchor for prosthetic cardiac valve devices
EP4203857A4 (en) 2020-08-31 2024-10-09 Shifamed Holdings, LLC INTERFACE FOR HEART VALVE PROSTHESIS AND RELEASE SYSTEMS
WO2022066720A1 (en) 2020-09-22 2022-03-31 Shifamed Holdings, Llc Prosthetic cardiac valve sensor devices, systems, and methods with imaging
US20230355380A1 (en) 2020-09-22 2023-11-09 Shifamed Holdings, Llc Systems, methods, and devices for expandable sensors
US20220387755A1 (en) 2021-06-03 2022-12-08 Cardiovascular Systems, Inc. Echolucent Intravascular Cannula and Echolucent Locating of Portions of Intravascular Medical Devices
WO2023091254A1 (en) 2021-11-19 2023-05-25 Edwards Lifesciences Corporation Prosthetic valve docking device
WO2024187023A2 (en) 2023-03-07 2024-09-12 Shifamed Holdings, Llc Prosthetic cardiac valve device, systems, and methods

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5327905A (en) * 1992-02-14 1994-07-12 Boaz Avitall Biplanar deflectable catheter for arrhythmogenic tissue ablation
US8323241B2 (en) * 2009-06-24 2012-12-04 Shifamed Holdings, Llc Steerable medical delivery devices and methods of use
US8920369B2 (en) 2009-06-24 2014-12-30 Shifamed Holdings, Llc Steerable delivery sheaths
US9017408B2 (en) * 2010-02-16 2015-04-28 Nlt Spine Ltd. Medical device lock mechanism
US20180235443A1 (en) * 2011-01-31 2018-08-23 Boston Scientific Scimed, Inc. Articulation section with locking
WO2018112429A1 (en) 2016-12-16 2018-06-21 Edwards Lifesciences Corporation Deployment systems, tools, and methods for delivering an anchoring device for a prosthetic valve

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of EP3866900A4

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11833034B2 (en) 2016-01-13 2023-12-05 Shifamed Holdings, Llc Prosthetic cardiac valve devices, systems, and methods
US12290456B2 (en) 2018-08-21 2025-05-06 Shifamed Holdings, Llc Prosthetic cardiac valve devices, systems, and methods
US11672657B2 (en) 2018-10-05 2023-06-13 Shifamed Holdings, Llc Prosthetic cardiac valve devices, systems, and methods
US11471282B2 (en) 2019-03-19 2022-10-18 Shifamed Holdings, Llc Prosthetic cardiac valve devices, systems, and methods
WO2021183610A1 (en) 2020-03-13 2021-09-16 Shifamed Holdings, Llc Prosthetic cardiac valve devices, systems, and methods
WO2021207545A1 (en) 2020-04-08 2021-10-14 Shifamed Holdings, Llc Valve delivery system
WO2022046678A1 (en) 2020-08-31 2022-03-03 Shifamed Holdings, Llc Interface for prosthetic cardiac valve and delivery systems
EP4203857A4 (en) * 2020-08-31 2024-10-09 Shifamed Holdings, LLC INTERFACE FOR HEART VALVE PROSTHESIS AND RELEASE SYSTEMS
WO2022262117A1 (zh) * 2021-06-17 2022-12-22 上海臻亿医疗科技有限公司 一种心脏瓣膜的锚固装置

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EP3866900A4 (en) 2022-06-22
EP3866900B1 (en) 2026-01-28
AU2019362078B2 (en) 2025-08-07
EP4721804A2 (en) 2026-04-08
AU2019362078A1 (en) 2021-05-13
US20210378823A1 (en) 2021-12-09
EP3866900A1 (en) 2021-08-25
JP7489975B2 (ja) 2024-05-24
JP2024105522A (ja) 2024-08-06

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