WO2016018448A1 - Systems and methods for applying reduced pressure therapy - Google Patents

Systems and methods for applying reduced pressure therapy Download PDF

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Publication number
WO2016018448A1
WO2016018448A1 PCT/US2014/066441 US2014066441W WO2016018448A1 WO 2016018448 A1 WO2016018448 A1 WO 2016018448A1 US 2014066441 W US2014066441 W US 2014066441W WO 2016018448 A1 WO2016018448 A1 WO 2016018448A1
Authority
WO
WIPO (PCT)
Prior art keywords
pressure
canister
negative pressure
wound
flow path
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2014/066441
Other languages
English (en)
French (fr)
Inventor
Alex Fowler
William W. Gregory
William Joseph JAECKLEIN
Kathryn Ann LEIGH
Paul N. MINOR
Michael Mosholder
Andrew P. MUSER
Felix C. Quintanar
John P. RACETTE
Christopher ROUSEFF
Matthew Smith
W. Len SMITH
Mark Schaefer
Anthony G. TRUPIANO
John Wyatt
Annaliese YEAMAN
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Smith and Nephew Inc
Original Assignee
Smith and Nephew Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to CN201480082413.7A priority Critical patent/CN106687154B/zh
Priority to EP19209497.7A priority patent/EP3659638A1/en
Priority to JP2017505135A priority patent/JP6644764B2/ja
Priority to EP14815987.4A priority patent/EP3174569B1/en
Priority to US15/500,495 priority patent/US10744239B2/en
Priority to AU2014402290A priority patent/AU2014402290B2/en
Priority to BR112017001969A priority patent/BR112017001969A2/pt
Application filed by Smith and Nephew Inc filed Critical Smith and Nephew Inc
Priority to CA2956572A priority patent/CA2956572C/en
Publication of WO2016018448A1 publication Critical patent/WO2016018448A1/en
Anticipated expiration legal-status Critical
Priority to US15/443,555 priority patent/US20170165405A1/en
Priority to US16/834,189 priority patent/US12133789B2/en
Priority to US16/994,182 priority patent/US12115298B2/en
Priority to US18/908,652 priority patent/US20250025349A1/en
Ceased legal-status Critical Current

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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61M1/60—Containers for suction drainage, adapted to be used with an external suction source
    • A61M1/602—Mechanical means for preventing flexible containers from collapsing when vacuum is applied inside, e.g. stents
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    • A61F13/00—Bandages or dressings; Absorbent pads
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    • A61M1/984—Containers specifically adapted for negative pressure wound therapy portable on the body
    • A61M1/985—Containers specifically adapted for negative pressure wound therapy portable on the body the dressing itself forming the collection container
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Definitions

  • Embodiments of the present disclosure relate to methods and apparatuses for dressing and treating a wound with reduced pressure therapy or topical negative pressure (TNP) therapy.
  • embodiments disclosed herein relate to negative pressure therapy devices, methods for controlling the operation of TNP systems, and methods of using TNP systems.
  • TNP Topical negative pressure
  • TNP Topical negative pressure
  • Such therapy is widely recognized as a beneficial mechanism for improving the healing rate of a wound.
  • Such therapy is applicable to a broad range of wounds such as incisional wounds, open wounds and abdominal wounds or the like.
  • TNP therapy assists in the closure and healing of wounds by reducing tissue oedema, encouraging blood flow, stimulating the formation of granulation tissue, removing excess exudates and may reduce bacterial load and, thus, infection to the wound. Furthermore, TNP therapy permits less outside disturbance of the wound and promotes more rapid healing.
  • a housing having a source of negative pressure configured to be in fluidic communication with a wound dressing, the source of negative pressure configured to aspirate fluid from the wound.
  • the apparatus also includes a pressure sensor configured to measure pressure in a fluid flow path configured to fluidically connect the wound dressing and the source of negative pressure and a controller configured to operate the source of negative pressure.
  • the controller is configured to receive measurement of pressure in the fluid flow path from the pressure sensor, determine a rate of flow in the fluid flow path, upon initiation of negative pressure wound therapy, detect presence of one or more leaks in the fluid flow path based at least in part on the pressure in the fluid flow path and the rate of flow in the fluid flow path, and provide indication of presence of one or more leaks.
  • the apparatus of any of the preceding paragraph includes a housing that has an electronic display, and the controller is further configured to provide on the display a graphical representation of the rate of flow in the fluid flow path in response to detecting presence of one or more leaks.
  • the graphical representation of the rate of flow in the fluid flow path can include a gauge.
  • the apparatus of any of the preceding paragraphs includes a source of negative pressure that is a vacuum pump having a motor, and the controller is configured to determine the rate of flow in the fluid flow path by measuring a speed of the motor.
  • the apparatus can include a tachometer configured to measure the speed of the motor.
  • the controller can be further configured to measure a first plurality of motor speeds during a first period of time and to average the first plurality of motor speeds, the average being indicative of the rate of flow.
  • the controller can be further configured to measure a second plurality of motor speeds over a second period of time different from the first period of time and to average the second plurality of motor speeds, the average being indicative of the rate of flow.
  • the controller can be further configured to utilize the averages of the first and second plurality of motor speeds to determine at least one of presence of one or more leaks in the fluid flow path, presence of one or more blockages in the fluid flow path, low negative pressure in the fluid flow path, and high negative pressure in the fluid flow path.
  • the apparatus of any of the preceding claims includes a canister configured to collect fluid aspirated from the wound.
  • the controller can be further configured to detect a canister full condition by, in response to determining that the rate of flow satisfies a flow rate threshold indicative of a leak and that canister pressure does not satisfy a pressure threshold indicative of low negative pressure, detecting a change in a characteristic of pressure in the fluid flow path and detecting that the canister is full based at least in part of the detected change.
  • the change in the characteristic of pressure can include a plurality of changes in the amplitude of pressure and the controller is configured to detect that the canister is full by comparing at least some of the plurality of changes in the amplitude of pressure to a threshold.
  • a method of operating a negative pressure wound pressure therapy apparatus includes measuring pressure in a fluid flow path configured to fluidically connect a source of negative pressure and a wound dressing and measuring a rate of flow in the fluid flow path. The method also includes upon initiation of negative pressure wound therapy, detecting presence of one or more leaks in the fluid flow path based at least in part on the pressure in the fluid flow path and the rate of flow in the fluid flow path and providing indication of presence of one or more leaks. The method can be performed by a controller of the negative wound pressure therapy apparatus.
  • the method of any of the preceding paragraph includes providing, on a display, a graphical representation of the rate of flow in the fluid flow path in response to detecting presence of one or more leaks.
  • the graphical representation of the rate of flow in the fluid flow can include a gauge. Measuring the rate of fluid in the fluid flow path can include measuring a speed of a motor operating a negative pressure source.
  • the method of any of the preceding paragraphs further includes measuring a first plurality of motor speeds during a first period of time and averaging the first plurality of motor speeds, the average being indicative of the rate of flow.
  • the method can further include measuring a second plurality of motor speeds over a second period of time different from the first period of time and averaging the second plurality of motor speeds, the average being indicative of the rate of flow.
  • the method can further include utilizing the averages of the first and second plurality of motor speeds to determine at least one of presence of one or more leaks in the fluid flow path, presence of one or more blockages in the fluid flow path, low negative pressure in the fluid flow path, and high negative pressure in the fluid flow path.
  • the method of any of the preceding paragraphs includes in response to determining that the rate of flow satisfies a flow rate threshold indicative of a leak and canister pressure does not satisfy a pressure threshold indicative of low negative pressure, detecting whether a canister is full by detecting a change in a characteristic of pressure in the fluid flow path and detecting that the canister is full based at least in part of the detected change.
  • the change in the characteristic of pressure can include a plurality of changes in the amplitude of pressure and detecting that the canister is full comprises comparing at least some of the plurality of changes in the amplitude of pressure to a threshold.
  • a canister for use in negative pressure wound therapy includes a first wall and a second wall opposite the first wall, the first and second walls defining an interior volume configured to collect wound exudate aspirated from a wound.
  • the canister also includes a reinforcement element attached to the first wall and extending toward the second wall, the reinforcement element dimensioned to prevent collapse of at least one of the first and second walls when negative pressure is applied to the canister.
  • the canister of the preceding paragraph includes a protruding element that has a hexagonal shape.
  • the protruding element can have at least one hole. At least a part of the protruding element can be configured to be in contact with the second wall when negative pressure is not applied the canister. When negative pressure is applied to the canister, at least a part of the protruding element can be configured to be in contact with the second wall.
  • the first and second walls can include plastic material and the interior volume can be configured to hold about 800 mL of fluid.
  • a source of negative pressure can be configured to be in fluid communication with the canister.
  • an apparatus for applying negative pressure therapy includes a source of negative pressure configured to be in fluidic communication with a plurality of wound dressings, the source of negative pressure further configured to aspirate fluid from a plurality of wounds.
  • the apparatus also includes a controller configured to operate the source of negative pressure to aspirate fluid from one or more wounds from the plurality of wounds.
  • the controller further is configured to receive a request to apply negative pressure wound therapy to a single wound or at least two wounds from the plurality of wounds, based on the request, activate the source of negative pressure to aspirate fluid from the wound or at least two wounds, based on the request, determine a rate of flow in the fluid flow path configured to fludically connect the negative pressure source and the wound or the negative pressure source and the at least two wounds, and detect a blockage in the fluid flow path by comparing the rate of flow to a first blockage threshold corresponding to aspirating fluid from the wound or a second blockage threshold corresponding to aspirating fluid from the at least two wounds.
  • the apparatus of the preceding paragraph includes a controller further configured to determine the second threshold by modifying the first threshold. Modifying the first threshold can include increasing the first threshold.
  • he apparatus of the preceding two paragraphs further includes a user interface, and wherein the request is received from the user interface.
  • the user interface can include a touchscreen display.
  • the apparatus of any of the preceding paragraphs further includes a transmitter configured to communicate with a remote computing device when the apparatus is within a coverage area of the remote computing device so as to enable the remote computing device to determine whether the apparatus is within the coverage area.
  • the transmitter can be configured to repeatedly communicate with the remote computing device to cause the remote computing device to determine a first time when the apparatus is removed from the coverage area and a second time when the apparatus is returned to the coverage area, thereby causing the remote computing device to determine a duration of time that the apparatus is outside the coverage area based at least on a comparison of the first time and the second time.
  • the transmitter can be configured to transmit a signal using a substantially constant signal strength to enable the remote computing device to determine a location of the apparatus relative to the coverage area based at least on a signal strength of a signal received by the remote computing device from the transmitter.
  • the transmitter can be configured to transmit a signal that does not enable the remote computing device to detect a presence of the apparatus in the coverage area when the apparatus is positioned outside the coverage area.
  • Figure 1 illustrates a reduced pressure wound therapy system according to some embodiments.
  • Figures 2A-2C illustrate a pump assembly and canister according to some embodiments.
  • Figure 3 illustrates an electrical component schematic of a pump assembly according to some embodiments.
  • Figure 4 illustrates a firmware and/or software diagram according to some embodiments.
  • Figures 5A-5I illustrate graphical user interface screens according to some embodiments.
  • Figures 6A-6G illustrate alarms screens according to some embodiments.
  • Figures 7A-7C illustrate a canister stiffener according to some embodiments.
  • Figure 8 illustrates a process of providing negative pressure wound therapy according to some embodiments.
  • Figure 9 illustrates pressure pulses according to some embodiments.
  • Figure 10 illustrates a system for location monitoring according to some embodiments.
  • Embodiments disclosed herein relate to systems and methods of treating a wound with reduced pressure.
  • reduced or negative pressure levels such as –X mmHg
  • a negative pressure value of –X mmHg reflects absolute pressure that is X mmHg below 760 mmHg or, in other words, an absolute pressure of (760–X) mmHg.
  • negative pressure that is“less” or“smaller” than X mmHg corresponds to pressure that is closer to atmospheric pressure (e.g.,–40 mmHg is less than–60 mmHg).
  • Negative pressure that is“more” or“greater” than–X mmHg corresponds to pressure that is further from atmospheric pressure (e.g., –80 mmHg is more than –60 mmHg).
  • local ambient atmospheric pressure is used as a reference point, and such local atmospheric pressure may not necessarily be, for example, 760 mmHg.
  • Embodiments of the present invention are generally applicable to use in topical negative pressure (TNP) or reduced pressure therapy systems.
  • TNP topical negative pressure
  • negative pressure wound therapy assists in the closure and healing of many forms of“hard to heal” wounds by reducing tissue oedema, encouraging blood flow and granular tissue formation, and/or removing excess exudate and can reduce bacterial load (and thus infection risk).
  • the therapy allows for less disturbance of a wound leading to more rapid healing.
  • TNP therapy systems can also assist in the healing of surgically closed wounds by removing fluid.
  • TNP therapy helps to stabilize the tissue in the apposed position of closure.
  • a further beneficial use of TNP therapy can be found in grafts and flaps where removal of excess fluid is important and close proximity of the graft to tissue is required in order to ensure tissue viability.
  • Figure 1 illustrates an embodiment of a negative or reduced pressure wound treatment (or TNP) system 100 comprising a wound filler 130 placed inside a wound cavity 110, the wound cavity sealed by a wound cover 120.
  • the wound filler 130 in combination with the wound cover 120 can be referred to as wound dressing.
  • a single or multi lumen tube or conduit 140 is connected the wound cover 120 with a pump assembly 150 configured to supply reduced pressure.
  • the wound cover 120 can be in fluidic communication with the wound cavity 110.
  • the pump assembly can be a canisterless pump assembly (meaning that exudate is collected in the wound dressing or is transferred via tube 140 for collection to another location).
  • any of the pump assembly embodiments disclosed herein can be configured to include or support a canister. Additionally, in any of the system embodiments disclosed herein, any of the pump assembly embodiments can be mounted to or supported by the dressing, or adjacent to the dressing.
  • the wound filler 130 can be any suitable type, such as hydrophilic or hydrophobic foam, gauze, inflatable bag, and so on.
  • the wound filler 130 can be conformable to the wound cavity 110 such that it substantially fills the cavity.
  • the wound cover 120 can provide a substantially fluid impermeable seal over the wound cavity 110.
  • the wound cover 120 can have a top side and a bottom side, and the bottom side adhesively (or in any other suitable manner) seals with wound cavity 110.
  • the conduit 140 or lumen or any other conduit or lumen disclosed herein can be formed from polyurethane, PVC, nylon, polyethylene, silicone, or any other suitable material.
  • the wound cover 120 can have a port (not shown) configured to receive an end of the conduit 140.
  • the conduit 140 can otherwise pass through and/or under the wound cover 120 to supply reduced pressure to the wound cavity 110 so as to maintain a desired level of reduced pressure in the wound cavity.
  • the conduit 140 can be any suitable article configured to provide at least a substantially sealed fluid flow pathway between the pump assembly 150 and the wound cover 120, so as to supply the reduced pressure provided by the pump assembly 150 to wound cavity 110.
  • the wound cover 120 and the wound filler 130 can be provided as a single article or an integrated single unit. In some embodiments, no wound filler is provided and the wound cover by itself may be considered the wound dressing.
  • the wound dressing may then be connected, via the conduit 140, to a source of negative pressure, such as the pump assembly 150.
  • the pump assembly 150 can be miniaturized and portable, although larger conventional pumps such can also be used.
  • the wound cover 120 can be located over a wound site to be treated.
  • the wound cover 120 can form a substantially sealed cavity or enclosure over the wound site.
  • the wound cover 120 can be configured to have a film having a high water vapour permeability to enable the evaporation of surplus fluid, and can have a superabsorbing material contained therein to safely absorb wound exudate.
  • a wound it is to be understood that the term wound is to be broadly construed and encompasses open and closed wounds in which skin is torn, cut or punctured or where trauma causes a contusion, or any other surficial or other conditions or imperfections on the skin of a patient or otherwise that benefit from reduced pressure treatment.
  • a wound is thus broadly defined as any damaged region of tissue where fluid may or may not be produced.
  • wounds include, but are not limited to, acute wounds, chronic wounds, surgical incisions and other incisions, subacute and dehisced wounds, traumatic wounds, flaps and skin grafts, lacerations, abrasions, contusions, burns, diabetic ulcers, pressure ulcers, stoma, surgical wounds, trauma and venous ulcers or the like.
  • the components of the TNP system described herein can be particularly suited for incisional wounds that exude a small amount of wound exudate.
  • Some embodiments of the system are designed to operate without the use of an exudate canister. Some embodiments can be configured to support an exudate canister. In some embodiments, configuring the pump assembly 150 and tubing 140 so that the tubing 140 can be quickly and easily removed from the pump assembly 150 can facilitate or improve the process of dressing or pump changes, if necessary. Any of the pump embodiments disclosed herein can be configured to have any suitable connection between the tubing and the pump.
  • the pump assembly 150 can be configured to deliver negative pressure of approximately -80 mmHg, or between about -20 mmHg and -200 mmHg. Note that these pressures are relative to normal ambient atmospheric pressure thus, -200 mmHg would be about 560 mmHg in practical terms.
  • the pressure range can be between about -40 mmHg and -150 mmHg. Alternatively a pressure range of up to -75 mmHg, up to -80 mmHg or over -80 mmHg can be used. Also a pressure range of below -75 mmHg can be used. Alternatively a pressure range of over approximately -100 mmHg, or even 150 mmHg, can be supplied by the pump assembly 150.
  • the pump assembly 150 is configured to provide continuous or intermittent negative pressure therapy.
  • Continuous therapy can be delivered at above -25 mmHg, -25 mmHg, -40 mmHg, -50 mmHg, -60 mmHg, -70 mmHg, -80 mmHg, -90 mmHg, -100 mmHg, -120 mmHg, -140 mmHg, -160 mmHg, -180 mmHg, -200 mmHg, or below -200 mmHg.
  • Intermittent therapy can be delivered between low and high negative pressure setpoints.
  • Low setpoint can be set at above 0 mmHg, 0 mmHg, -25 mmHg, -40 mmHg, -50 mmHg, -60 mmHg, -70 mmHg, -80 mmHg, -90 mmHg, -100 mmHg, -120 mmHg, -140 mmHg, -160 mmHg, -180 mmHg, or below -180 mmHg.
  • High setpoint can be set at above -25 mmHg, -40 mmHg, -50 mmHg, -60 mmHg, -70 mmHg, -80 mmHg, -90 mmHg, -100 mmHg, -120 mmHg, -140 mmHg, -160 mmHg, -180 mmHg, -200 mmHg, or below -200 mmHg.
  • negative pressure at low setpoint can be delivered for a first time duration, and upon expiration of the first time duration, negative pressure at high setpoint can be delivered for a second time duration. Upon expiration of the second time duration, negative pressure at low setpoint can be delivered.
  • the first and second time durations can be same or different values.
  • the first and second durations can be selected from the following range: less than 2 minutes, 2 minutes, 3 minutes, 4 minutes, 6 minutes, 8 minutes, 10 minutes, or greater than 10 minutes.
  • switching between low and high setpoints and vice versa can be performed according to a step waveform, square waveform, sinusoidal waveform, and the like.
  • the wound filler 130 is inserted into the wound cavity 110 and wound cover 120 is placed so as to seal the wound cavity 110.
  • the pump assembly 150 provides a source of a negative pressure to the wound cover 120, which is transmitted to the wound cavity 110 via the wound filler 130.
  • Fluid e.g., wound exudate
  • Fluid is drawn through the conduit 140, and can be stored in a canister.
  • fluid is absorbed by the wound filler 130 or one or more absorbent layers (not shown).
  • Wound dressings that may be utilized with the pump assembly and other embodiments of the present application include Renasys-F, Renasys-G, Renasys AB, and Pico Dressings available from Smith & Nephew. Further description of such wound dressings and other components of a negative pressure wound therapy system that may be used with the pump assembly and other embodiments of the present application are found in U.S. Patent Publication Nos. 2011/0213287, 2011/0282309, 2012/0116334, 2012/0136325, and 2013/0110058, which are incorporated by reference in their entirety. In other embodiments, other suitable wound dressings can be utilized.
  • Pump Assembly and Canister can be utilized.
  • FIG. 2A illustrates a front view 200A of a pump assembly 230 and canister 220 according to some embodiments.
  • the pump assembly 230 comprises one or more indicators, such as visual indicator 202 configured to indicate alarms and visual indicator 204 configured to indicate status of the TNP system.
  • the indicators 202 and 204 can be configured to alert a user, such as patient or medical care provider, to a variety of operating and/or failure conditions of the system, including alerting the user to normal or proper operating conditions, pump failure, power supplied to the pump or power failure, detection of a leak within the wound cover or flow pathway, suction blockage, or any other similar or suitable conditions or combinations thereof.
  • the pump assembly 230 can comprise additional indicators.
  • the pump assembly can use a single indicator or multiple indicators. Any suitable indicator can be used such as visual, audio, tactile indicator, and so on.
  • the indicator 202 can be configured to signal alarm conditions, such as canister full, power low, conduit 140 disconnected, seal broken in the wound seal 120, and so on.
  • the indicator 202 can be configured to display red flashing light to draw user’s attention.
  • the indicator 204 can be configured to signal status of the TNP system, such as therapy delivery is ok, leak detected, and so on.
  • the indicator 204 can be configured to display one or more different colors of light, such as green, yellow, etc. For example, green light can be emitted when the TNP system is operating properly and yellow light can be emitted to indicate a warning.
  • the pump assembly 230 comprises a display or screen 206 mounted in a recess 208 formed in a case of the pump assembly.
  • the display 206 can be a touch screen display.
  • the display 206 can support playback of audiovisual (AV) content, such as instructional videos.
  • AV audiovisual
  • the display 206 can be configured to render a number of screens or graphical user interfaces (GUIs) for configuring, controlling, and monitoring the operation of the TNP system.
  • the pump assembly 230 comprises a gripping portion 210 formed in the case of the pump assembly.
  • the gripping portion 210 can be configured to assist the user to hold the pump assembly 230, such as during removal of the canister 220.
  • the canister 220 can be replaced with another canister, such as when the canister 220 has been filled with fluid.
  • the pump assembly 230 comprises one or more keys or buttons 212 configured to allow the user to operate and monitor the operation of the TNP system. As is illustrated, there buttons 212a, 212b, and 212c are included. Button 212a can be configured as a power button to turn on/off the pump assembly 230. Button 212b can be configured as a play/pause button for the delivery of negative pressure therapy. For example, pressing the button 212b can cause therapy to start, and pressing the button 212b afterward can cause therapy to pause or end. Button 212c can be configured to lock the display 206 and/or the buttons 212. For instance, button 212c can be pressed so that the user does not unintentionally alter the delivery of the therapy.
  • Button 212c can be depressed to unlock the controls. In other embodiments, additional buttons can be used or one or more of the illustrated buttons 212a, 212b, or 212c can be omitted. Multiple key presses and/or sequences of key presses can be used to operate the pump assembly 230.
  • the pump assembly 230 includes one or more latch recesses 222 formed in the cover. In the illustrated embodiment, two latch recesses 222 can be formed on the sides of the pump assembly 230. The latch recesses 222 can be configured to allow attachment and detachment of the canister 220 using one or more canister latches 221.
  • the pump assembly 230 comprises an air outlet 224 for allowing air removed from the wound cavity 110 to escape. Air entering the pump assembly can be passed through one or more suitable filters, such as antibacterial filters. This can maintain reusability of the pump assembly.
  • the pump assembly 230 includes one or more strap mounts 226 for connecting a carry strap to the pump assembly 230 or for attaching a cradle. In the illustrated embodiment, two strap mounts 226 can be formed on the sides of the pump assembly 230. In some embodiments, various of these features are omitted and/or various additional features are added to the pump assembly 230.
  • the canister 220 is configured to hold fluid (e.g., exudate) removed from the wound cavity 110.
  • the canister 220 includes one or more latches 221 for attaching the canister to the pump assembly 230.
  • the canister 220 comprises two latches 221 on the sides of the canister.
  • the exterior of the canister 220 can formed from frosted plastic so that the canister is substantially opaque and the contents of the canister and substantially hidden from plain view.
  • the canister 220 comprises a gripping portion 214 formed in a case of the canister.
  • the gripping portion 214 can be configured to allow the user to hold the pump assembly 220, such as during removal of the canister from the apparatus 230.
  • the canister 220 includes a substantially transparent window 216, which can also include graduations of volume.
  • the illustrated 300 mL canister 220 includes graduations of 50 mL, 100 mL, 150 mL, 200 mL, 250 mL, and 300 mL.
  • Other embodiments of the canister can hold different volume of fluid and can include different graduation scale.
  • the canister can be an 800 mL canister.
  • the canister 220 comprises a tubing channel 218 for connecting to the conduit 140.
  • various of these features, such as the gripping portion 214, are omitted and/or various additional features are added to the canister 220.
  • Any of the disclosed canisters may include or may omit a solidifier.
  • FIG. 2B illustrates a rear view 200B of the pump assembly 230 and canister 220 according to some embodiments.
  • the pump assembly 230 comprises a speaker port 232 for producing sound.
  • the pump assembly 230 includes a filter access door 234 for accessing and replacing one or more filters, such as antibacterial filters.
  • the pump assembly 230 comprises a gripping portion 236 formed in the case of the pump assembly.
  • the gripping portion 236 can be configured to allow the user to hold the pump assembly 230, such as during removal of the canister 220.
  • the pump assembly 230 includes one or more covers 238 configured to as screw covers and/or feet or protectors for placing the pump assembly 230 on a surface.
  • the covers 230 can be formed out of rubber, silicone, or any other suitable material.
  • the pump assembly 230 comprises a power jack 239 for charging and recharging an internal battery of the pump assembly.
  • the power jack 239 can be a direct current (DC) jack.
  • the pump assembly can comprise a disposable power source, such as batteries, so that no power jack is needed.
  • the canister 220 includes one or more feet 244 for placing the canister on a surface.
  • the feet 244 can be formed out of rubber, silicone, or any other suitable material and can be angled at a suitable angle so that the canister 220 remains stable when placed on the surface.
  • the canister 220 comprises a tube mount relief 246 configured to allow one or more tubes to exit to the front of the device.
  • the canister 220 includes a stand or kickstand 248 for supporting the canister when it is placed on a surface. As explained below, the kickstand 248 can pivot between an opened and closed position. In closed position, the kickstand 248 can be latched to the canister 220. In some embodiments, the kickstand 248 can be made out of opaque material, such as plastic.
  • the kickstand 248 can be made out of transparent material.
  • the kickstand 248 includes a gripping portion 242 formed in the kickstand.
  • the gripping portion 242 can be configured to allow the user to place the kickstand 248 in the closed position.
  • the kickstand 248 comprises a hole 249 to allow the user to place the kickstand in the open position.
  • the hole 249 can be sized to allow the user to extend the kickstand using a finger.
  • FIG. 2C illustrates a view 200C of the pump assembly 230 separated from the canister 220 according to some embodiments.
  • the pump assembly 230 includes a vacuum attachment, connector, or inlet 252 through which a vacuum pump communicates negative pressure to the canister 220.
  • the pump assembly aspirates fluid, such as gas, from the wound via the inlet 252.
  • the pump assembly 230 comprises a USB access door 256 configured to allow access to one or more USB ports. In some embodiments, the USB access door is omitted and USB ports are accessed through the door 234.
  • the pump assembly 230 can include additional access doors configured to allow access to additional serial, parallel, and/or hybrid data transfer interfaces, such as SD, Compact Disc (CD), DVD, FireWire, Thunderbolt, PCI Express, and the like. In other embodiments, one or more of these additional ports are accessed through the door 234.
  • additional serial, parallel, and/or hybrid data transfer interfaces such as SD, Compact Disc (CD), DVD, FireWire, Thunderbolt, PCI Express, and the like.
  • additional serial, parallel, and/or hybrid data transfer interfaces such as SD, Compact Disc (CD), DVD, FireWire, Thunderbolt, PCI Express, and the like.
  • CD Compact Disc
  • Thunderbolt Thunderbolt
  • PCI Express PCI Express
  • FIG. 3 illustrates an electrical component schematic 300 of a pump assembly, such as the pump assembly 230, according to some embodiments.
  • Electrical components can operate to accept user input, provide output to the user, operate the pump assembly and the TNP system, provide network connectivity, and so on. Electrical components can be mounted on one or more printed circuit boards (PCBs).
  • PCBs printed circuit boards
  • the pump assembly can include multiple processors. It may be advantageous to utilize multiple processors in order to allocate or assign various tasks to different processors.
  • a first processor can be responsible for user activity and a second processor can be responsible for controlling the pump.
  • the pump assembly can comprise a user interface processor or controller 310 configured to operate one or more components for accepting user input and providing output to the user, such as the display 206, buttons 212, etc.
  • Input to the pump assembly and output from the pump assembly can controlled by an input/output (I/O) module 320.
  • the I/O module can receive data from one or more ports, such as serial, parallel, hybrid ports, and the like.
  • the processor 310 also receives data from and provides data to one or more expansion modules 360, such as one or more USB ports, SD ports, Compact Disc (CD) drives, DVD drives, FireWire ports, Thunderbolt ports, PCI Express ports, and the like.
  • the processor 310 along with other controllers or processors, stores data in one or more memory modules 350, which can be internal and/or external to the processor 310.
  • Any suitable type of memory can be used, including volatile and/or non-volatile memory, such as RAM, ROM, magnetic memory, solid-state memory, Magnetoresistive random-access memory (MRAM), and the like.
  • the processor 310 can be a general purpose controller, such as a low-power processor. In other embodiments, the processor 310 can be an application specific processor.
  • the processor 310 can be configured as a“central” processor in the electronic architecture of the pump assembly, and the processor 310 can coordinate the activity of other processors, such as a pump control processor 370, communications processor 330, and one or more additional processors 380 (e.g., processor for controlling the display 206, processor for controlling the buttons 212, etc.).
  • the processor 310 can run a suitable operating system, such as a Linux, Windows CE, VxWorks, etc.
  • the pump control processor 370 can be configured to control the operation of a negative pressure pump 390.
  • the pump 390 can be a suitable pump, such as a diaphragm pump, peristaltic pump, rotary pump, rotary vane pump, scroll pump, screw pump, liquid ring pump, diaphragm pump operated by a piezoelectric transducer, voice coil pump, and the like.
  • the pump control processor 370 can measure pressure in a fluid flow path, using data received from one or more pressure sensors, calculate the rate of fluid flow, and control the pump.
  • the pump control processor 370 can control a pump motor so that a desired level of negative pressure is achieved in the wound cavity 110.
  • the desired level of negative pressure can be pressure set or selected by the user.
  • the pump control processor 370 controls the pump (e.g., pump motor) using pulse-width modulation (PWM).
  • a control signal for driving the pump can be a 0-100% duty cycle PWM signal.
  • the pump control processor 370 can perform flow rate calculations and detect various conditions in a flow path.
  • the pump control processor 370 can communicate information to the processor 310.
  • the pump control processor 370 can include internal memory and/or can utilize memory 350.
  • the pump control processor 370 can be a low- power processor.
  • a communications processor 330 can be configured to provide wired and/or wireless connectivity.
  • the communications processor 330 can utilize one or more antennas 340 for sending and receiving data.
  • the communications processor 330 can provide one or more of the following types of connections: Global Positioning System (GPS) technology, cellular connectivity (e.g., 2G, 3G, LTE, 4G), WiFi connectivity, Internet connectivity, and the like. Connectivity can be used for various activities, such as pump assembly location tracking, asset tracking, compliance monitoring, remote selection, uploading of logs, alarms, and other operational data, and adjustment of therapy settings, upgrading of software and/or firmware, and the like.
  • the communications processor 330 can provide dual GPS/cellular functionality.
  • Cellular functionality can, for example, be 3G functionality.
  • the device location can be determined using the 3G network connection, such as by using cell identification, triangulation, forward link timing, and the like.
  • the pump assembly can include a SIM card, and SIM-based positional information can be obtained.
  • the communications processor 330 can communicate information to the processor 310.
  • the communications processor 330 can include internal memory and/or can utilize memory 350.
  • the communications processor 330 can be a low-power processor.
  • the pump assembly can track and store various data, such as one or more of positioning data, therapy parameters, logs, device data, and so on.
  • the pump assembly can track and log therapy and other operational data. Data can be stored, for example, in the memory 350.
  • the device using the connectivity provided by the communications processor 330, the device can upload any of the data stored, maintained, and/or tracked by the pump assembly.
  • the following information can be uploaded to a remote computer or server: activity log(s), which includes therapy delivery information, such as therapy duration, alarm log(s), which includes alarm type and time of occurrence; error log, which includes internal error information, transmission errors, and the like; therapy duration information, which can be computed hourly, daily, and the like; total therapy time, which includes therapy duration from first applying a particular therapy program or programs; lifetime therapy information; device information, such as the serial number, software version, battery level, etc.; device location information; patient information; and so on.
  • the device can also download various operational data, such as therapy selection and parameters, firmware and software patches and upgrades, and the like.
  • the pump assembly can provide Internet browsing functionality using one or more browser programs, mail programs, application software (e.g., apps), etc.
  • the communications processor 330 can use the antenna 340 to communicate a location of the pump assembly, such as a location of a housing of the pump assembly, to other devices in the proximity (for example, within 10, 20, or 50 meters and the like) of the pump assembly.
  • the communications processor 330 can perform one-way or two-way communication with the other devices depending on the implementation.
  • the communications transmitted by the communications processor 330 can include identifying information to uniquely identify the pump assembly relative to one or more other pump assemblies also in the proximity of the pump assembly. For example, identifying information can include a serial number or a value derived from the serial number.
  • the signal strength of the transmitted communications by the communications processor 330 can be controlled (for example, maintained at a constant or substantially constant level) to enable another device to determine a distance to the pump assembly, such as a distance between the device and the pump assembly.
  • the communications processor 330 can communicate with other devices in the proximity of the pump assembly so that the communications processor 330 can itself determine a distance from the pump assembly to the other devices.
  • the communications processor 330 in such embodiments, can track and store the distance from the pump assembly to the other devices or indications of change in the distance over time, and the communications processor 330 can later provide this information to the other devices. For instance, the communications processor 330 can determine a duration of time during which the pump assembly has been removed from a coverage area of a device and subsequently report this time to the device upon being returned to the coverage area.
  • FIG. 4 illustrates a firmware and/or software diagram 400 according to some embodiments.
  • a pump assembly 420 includes a user interface processor firmware and/or software 422, which can be executed by the user interface processor 310, pump control processor firmware and/or software 424, which can be executed by the pump control processor 370, communications processor firmware and/or software 426, which can be executed by the communications processor 330, and additional processor(s) firmware and/or software 428, which can be executed by one or more additional processors 380.
  • the pump assembly 420 can be connected to a computer 410, which can be a laptop, desktop, tablet, smartphone, and the like.
  • a wired or wireless connection can be utilized to connect the computer 410 to the pump assembly 420.
  • a USB connection can be used.
  • the connection between the computer 410 and the pump assembly 420 can be used for various activities, such as pump assembly location tracking, asset tracking, compliance monitoring, selection, uploading of logs, alarms, and other operational data, and adjustment of therapy settings, upgrading of software and/or firmware, and the like.
  • the pump assembly 420 and computer 410 can communicate with a remote computer or server 440 via the cloud 430.
  • the remote computer 440 can include a data storage module 442 and a web interface 444 for accessing the remote computer.
  • connection between the computer 410 and pump assembly 420 can be utilized to perform one or more of the following: initialization and programming of the pump assembly 420, firmware and/or software upgrades, maintenance and troubleshooting, selecting and adjusting therapy parameters, and the like.
  • the computer 410 can execute an application program for communicating the pump assembly 420.
  • the pump assembly 420 can upload various data to the remote computer (or multiple remote computers) 440 via the cloud 430.
  • upload data can include activity log(s), alarm log(s), therapy duration information, total therapy time, lifetime therapy information, device information, device location information, patient information, etc.
  • the pump assembly 420 can receive and process commands received from the cloud 430. Operation of the Pump Assembly
  • the pump assembly 230 can be operated using a touchscreen interface displayed on the screen 206.
  • Various graphical user interface (GUI) screens present information on systems settings and operations, among other things.
  • the touchscreen interface can be actuated or operated by a finger (or a stylus or another suitable device). Tapping a touchscreen cam result in making a selection.
  • a user can touch screen and hold and drag to view the selections. Additional or alternative ways to operate the touchscreen interface can be implemented, such as multiple finger swipes for scrolling, multiple finger pinch for zooming, and the like.
  • FIGS 5A-5I illustrate graphical user interface screens according to some embodiments.
  • the GUI screens can be displayed on the screen 206, which can be configured as a touchscreen interface. Information displayed on the screens can be generated based on input received from the user.
  • the GUI screens can be utilized for initializing the device, selecting and adjusting therapy settings, monitoring device operation, uploading data to the network (e.g., cloud), and the like.
  • the illustrated GUI screens can be generated directly by an operating system running on the processor 310 and/or by a graphical user interface layer or component running on the operating system. For instance, the screens can be developed using Qt framework available from Digia.
  • FIG. 5A illustrates a therapy settings screen 500A according to some embodiments.
  • the therapy settings screen 500A can be displayed after the pump assembly has been initialized (e.g., screen 500A can function as a home screen).
  • the therapy settings screen 500A includes a status bar 502 that comprises icons indicating operational parameters of the device.
  • Animated icon 503 is a therapy delivery indicator. When therapy is not being delivered, icon 503 can be static and displayed in a color, such as gray. When therapy is being delivered, icon 503 can turn a different color, such as orange, and becomes animated, such as, rotates, pulsates, become filled with color (see Figure 5C), etc.
  • Other status bar icons include a volume indicator and a battery indicator, and may include additional icons, such as wireless connectivity.
  • the therapy settings screen 500A includes date/time and information.
  • the therapy settings screen 500A includes a menu 510 that comprises menu items 512 for accessing device settings, 514 for accessing logs, 516 for accessing help, and 518 (see, for example, Figures 5C and 5E) for returning to the therapy settings screen (or home screen) from other screens.
  • the pump assembly can be configured so that after a period of inactivity, such as not receiving input from the user, therapy settings screen 500A (or home screen) is displayed. Additional or alternative controls, indicators, messages, icons, and the like can be used.
  • the therapy settings screen 500A includes negative pressure up and down controls 522 and 524. Up and down controls 522 and 524 can be configured to adjust the negative pressure setpoint by a suitable step size, such as ⁇ 5 mmHg. As is indicated by label 526, the current therapy selection is -80 mmHg (or 80 mmHg below atmospheric pressure).
  • the therapy settings screen 500A includes continuous/intermittent therapy selection 530. Continuous therapy selection screen can be accessed via control 532 and intermittent therapy selection screen can be accessed via control 534. As is illustrated, the current therapy setting is to continuously deliver negative pressure at -80 mmHg. As is indicated by message 528, therapy delivery can be initiated by pressing a button, such as button 212b on the pump assembly 230.
  • the therapy settings screen 500A includes Y-connector selection 535 for treating multiple wounds, such as two, three, etc. wounds, with one pump assembly 230.
  • Control 536 selects treatment of a single wound
  • control 538 selects treatment of more than one wound by the pump assembly.
  • the current selection is to treat a single wound. Additional or alternative controls, indicators, messages, icons, and the like can be used.
  • FIG. 5B illustrates therapy settings screen 500B for delivering intermittent therapy according to some embodiments.
  • Screen 500B can be accessed via control 534.
  • Therapy settings screen 500B includes intermittent therapy settings 540 and 545.
  • current therapy selection is applying -80 mmHg of reduced pressure for 5 minutes followed by 2 minutes of applying atmospheric pressure (or turning off the vacuum pump).
  • Negative pressure levels and time durations can be adjusted by selecting one or more of controls 542, 544, 546, and 548 and operating the up or down controls 522 or 524 until desired values are selected.
  • more than two negative pressure values and corresponding durations can be selected for treatment of a wound.
  • a user can select three or more negative pressure values and corresponding durations. Additional or alternative controls, indicators, messages, icons, and the like can be used.
  • Figure 5C illustrates therapy delivery screen 500C according to some embodiments.
  • Screen 500C can be accessed by selecting desired therapy settings on the screen 500A or 500B and initiating therapy, such as by pressing the button 212b.
  • label 552 (“Delivering Therapy”) indicates that continuous therapy at -120 mmHg of reduced pressure (label 560) is being delivered to a wound.
  • Animated icon 503 indicates that therapy is being delivered by cycling though an animation. As is illustrated in Figures 5C and 5D, icon 503 is an energy burst having multiple petals, and the animation sequences through the petals becoming filled with orange color. Any other suitable animation or combination of animations can be used.
  • Message 529 indicates that therapy settings can be stopped or paused by pressing a button, such as button 212b, on the pump assembly 230.
  • Menu item 518 can be configured to return to the therapy settings screen (or home screen) 500A. Additional or alternative controls, indicators, messages, icons, and the like can be used.
  • Figure 5D illustrates therapy delivery screen 500D according to some embodiments.
  • Screen 500D can be displayed after the user has selected desired therapy settings on the screen 500B and has initiated therapy, such as by pressing button the 212b.
  • intermittent therapy is being delivered to a wound.
  • Label 551 and timer 554, respectively, indicate that negative pressure of -120 mmHg is being delivered to the wound for 5 minutes.
  • Timer 554 can be configured to show the remaining amount of time, for example, as a number (e.g.,“5 min”), as a relative amount (e.g., by adjusting the fill of the circle), and a combination of the two.
  • Labels 555 and 556 indicate that 0 mmHg (or atmospheric pressure) is scheduled to be delivered to the wound for duration of 2 minutes upon expiration of the time period (e.g., 5 minutes) for delivering the first amount of negative pressure (e.g., -120 mmHg).
  • Message 553 (“Leak Check”) indicates that the pump assembly 230 is performing a leak check. As is further explained below, the pump assembly 230 can perform a leak check when it initiates delivery of negative pressure therapy to determine if the fluid flow path is sufficiently free of leaks (e.g., is properly sealed).
  • message 553 can indicate this fact to the user, such as by displaying the message“Seal Achieved.”
  • Menu item 518 can be configured to return to the therapy settings screen (or home screen). Additional or alternative controls, indicators, messages, icons, and the like can be used.
  • FIG. 5E illustrates settings screen 500E according to some embodiments.
  • the settings screen 500E can be accessed by selecting menu item 512 (e.g., from screen 500A or 500B).
  • settings screen 500E includes a menu 560 for adjusting various operational parameters of the pump assembly 230, including alarm volume setting, compression setting 562, user mode setting (e.g., clinician or patient), language setting, time zone setting, flow meter 564, restore presets (e.g., factory presets), and device information. Attempting to set the user mode as clinician mode may prompt the user to enter a password or satisfy any other suitable security check.
  • Operating the pump assembly in clinician mode can provide unrestricted access to all features and settings, whereas operating the pump assembly in patient mode can prevent inadvertent changes to therapy settings by preventing access to one or more features and settings, such as therapy settings, compression settings, and the like.
  • Alternative or additional menu items can be displayed.
  • the illustrated menu 560 is an expanded version of the menu showing all menu items. In use, menu 560 may only partially fit on the screen, and the menu items can be accessed via the scroll bar 561 or via any other suitable alternative or additional controls. Additional or alternative controls, indicators, messages, icons, and the like can be used.
  • Figure 5F illustrates compression settings screen 500F according to some embodiments.
  • the screen 500F can be accessed by selecting the menu item 562.
  • the screen 500F includes three compression settings selections: low 572, medium 574, and high 576. As is explained below, these selections control the time it takes to reach a desired or set vacuum level at the wound. For example, selecting a high compression 576 will result in the most rapid wound dressing draw down.
  • Menu item 519 can be configured to return to the settings screen 500E.
  • compression settings screen 500F may be accessed only if clinician mode has been previously selected. A clinician may select appropriate compression setting based on one or more physiological parameters, such as wound type, patient’s age, physical condition, etc. Additional compression settings, such as very low, very high, and the like can be provided. Additional or alternative controls, indicators, messages, icons, and the like can be used.
  • Figure 5G illustrates flow meter screen 500G according to some embodiments.
  • the screen 500G can be accessed by selecting the menu item 564 in Figure 5E.
  • the screen 500G can visually depict the determined or calculated rate of air (or gas) flow in the fluid flow path, which can include the therapy unit assembly, wound dressing, and tubing connecting the therapy unit assembly to the wound dressing.
  • the screen 500G illustrates a gauge 580 that visually depicts the determined flow rate and can be used for detection of one or more leaks in the fluid flow path.
  • Other controls for depicting the flow rate can be alternatively or additionally used, such as horizontal or vertical bars, digital gauges, labels, and the like.
  • the gauge 580 includes a dial 584 with markings 581 indicating absence of leaks or a very small leak (positioned at the beginning of the dial), 582 indicating medium leak (positioned at the middle of the dial), and 583 indicating high leak (positioned at the end of the dial).
  • the gauge 580 also includes a needle 585 that indicates the determined leak rate on the dial 584.
  • the dial 584 can be configured to be filled in various colors that visually indicate the leak rate. For example, green color can indicate a low level leak, yellow color can indicate a higher level (or significant) leak, and red color can indicate a leak of a high level.
  • the gauge 580 can assist a user in locating leaks.
  • Other controls for depicting the leak rate can be alternatively or additionally used, such as horizontal or vertical bars, digital gauges, labels, and the like.
  • Figure 5H illustrates flow meter screen 500H according to some embodiments.
  • screen 500H illustrates a lower detected leak. This is depicted by the needle 585 being positioned closer to the marking 581 (e.g., needle 585 is to the left of marking 582).
  • detection of leaks exceeding a certain threshold may trigger an alarm. That is, in the event of a low vacuum level at the wound (e.g., due to high leak), the flow meter screen 500G can be displayed to help locate the leak (or leaks) in the fluid flow path.
  • Flow meter screen 500G or 500H can be displayed while therapy is being delivered by the pump assembly, as is illustrated by the animated icon 503.
  • Figure 5I illustrates alarms and troubleshooting screen 500I according to some embodiments.
  • the screen 500I can be accessed by selecting the menu item 516 for accessing help (see Figure 5E) and selecting alarms menu item from the help screen (not shown).
  • screen 500I includes a menu 588 with menu items for various alarm and troubleshooting categories, including over vacuum, high vacuum, blockage, canister flow, high flow/leak, and low or insufficient vacuum (as explained below) as well as technical failure (e.g., unrecoverable error), battery (e.g., low battery, critical low battery, battery failed), and inactivity (e.g., pump assembly is powered on an has been left without user interaction for longer than a certain period of time, such as 15 minutes).
  • technical failure e.g., unrecoverable error
  • battery e.g., low battery, critical low battery, battery failed
  • inactivity e.g., pump assembly is powered on an has been left without user interaction for longer than a certain period of time, such
  • Alternative or additional menu items can be displayed. Accessing a particular menu item can bring up a screen with step-by-step instructions to assist in resolving the corresponding alarm.
  • the instructions can include a combination of text, audio, video, etc.
  • the illustrated menu 588 is an expanded version of the menu showing all menu items. In use, menu 588 may only partially fit on the screen, and menu items can be accessed via the scroll bar 587 or via any other suitable alternative or additional controls. Additional or alternative controls, indicators, messages, icons, and the like can be used.
  • FIGS 6A-6G illustrate alarm screens according to some embodiments.
  • the illustrated screens can be displayed in response to a condition or set of conditions detected by the pump assembly in order to alert the user.
  • the therapy unit can perform one or more of the following: sound an audible alarm, display an alarm screen, illuminate the indicator 204 in a specific color, such as yellow.
  • the therapy unit can be configured to stop or suspend delivering therapy in the occurrence of an over vacuum or high vacuum alarm. If occurrence of other alarms is detected, the therapy unit can continue delivery of therapy.
  • Figure 6A illustrates a blockage alarm screen 600A according to some embodiments.
  • Indicator 601 indicates alarm condition.
  • Label 602 is a description of the alarm (e.g.,“WARNING BLOCKAGE”).
  • Icon 603 is configured to return the home screen, such as screen 500A.
  • Labels 604 and 605 respectively provide information about current therapy settings. As is illustrated, continuous therapy at -25 mmHg of reduced pressure is being applied to a wound.
  • Label 606 provides suggested action to correct the alarm (e.g., “Tubing or canister may be blocked”).
  • Icon 607 is configured to bring up alarms and troubleshooting screen 500I in case the user desires more detailed information regarding the alarms and troubleshooting.
  • Icon 608 is configured to silence the alarm permanently or temporarily. For some alarms, such as non-critical alarms, audible tones can be temporarily silenced by selecting icon 608. If the audible alarm has been temporarily silenced and a new alarm occurs, the audible alarm for the new alarm may sound and the new alarm may be displayed. When multiple alarm messages are present, the therapy assembly can alternate between the alarm screens.
  • Blockage alarm screen 600A can indicate detection of a blockage in the flow path, such as in a conduit connecting the canister (or pump in a canisterless system) with the wound dressing.
  • the alarm may be resolved by clearing the blockage.
  • the pump assembly may continue to attempt to provide desired therapy to the wound after blockage has been detected.
  • FIG. 6B illustrates an over vacuum alarm screen 600B according to some embodiments.
  • the description of the alarm is“OVER VACUUM,” and suggested action to correct the alarm is“Power Off/Power On to clear.”
  • This alarm screen can indicate that the therapy unit has detected an excessively high vacuum in the fluid flow path (e.g., exceeding -235mmHg or any other suitable value), potentially due to device malfunction.
  • the pump assembly can be configured to stop or suspend delivering therapy until the over vacuum condition has been corrected.
  • An audible alarm can be generated, which may not be paused (hence the icon 608 is not displayed in the screen 600B).
  • the alarm may be resolved by power cycling the pump assembly.
  • FIG. 6C illustrates a high vacuum alarm screen 600C according to some embodiments.
  • the description of the alarm is“HIGH VACUUM,” and suggested action to correct the alarm is“Power Off/Power On to clear.”
  • This alarm screen can indicate that the therapy unit has detected a high vacuum condition (e.g., exceeding -15mmHg above the therapy setpoint or any other suitable value), potentially due to a blockage or device malfunction.
  • the pump assembly can be configured to stop or suspend delivering therapy until the high vacuum condition has been corrected.
  • An audible alarm can be generated, which may not be paused (hence the icon 608 is not displayed in the screen 600C).
  • the alarm may be resolved by power cycling the pump assembly.
  • Figure 6D illustrates a canister full alarm screen 600D according to some embodiments.
  • the description of the alarm is“CANISTER FULL” because it has been detected that the canister is full or the internal canister filter is covered with fluid.
  • the alarm may be resolved by replacing the canister.
  • the pump assembly may continue to attempt to provide desired therapy to the wound.
  • the alarm may be silenced.
  • dressing full condition or dressing filter occluded condition can be detected and indicated in a manner similar to the canister full condition.
  • Figure 6E illustrates a low vacuum alarm screen 600E according to some embodiments.
  • the description of the alarm is“LOW VACUUM” because the detected pressure at the wound is lower than the desired negative pressure by a threshold amount, such as -15 mmHg or another suitable value.
  • a threshold amount such as -15 mmHg or another suitable value.
  • low vacuum condition can be detected if there is a leak in the fluid flow path that persists for longer than threshold duration, such as 30 seconds or any other suitable value.
  • the alarm may be resolved by checking the connections in the fluid flow path for leaks or checking the dressing for leaks.
  • the pump assembly may continue to attempt to provide desired therapy to the wound.
  • the gauge 580 may be displayed on the screen 600E, as is explained below in connection with Figure 6F.
  • the alarm may be silenced.
  • Figure 6F illustrates a leak alarm screen 600F according to some embodiments.
  • the description of the alarm is“LEAK” because a significant leak (e.g., a leak that exceeds a certain threshold leak rate) has been detected for a threshold duration, such as for longer than 2 minutes or any other suitable value.
  • the leak alarm screen 600F includes the gauge 580 illustrating the leak rate detected in the fluid flow path. As is illustrated by the position of the needle 585, a high flow leak has been detected, which has triggered the leak alarm. The alarm may be resolved by checking the connections in the fluid flow path for leaks or checking the dressing for leaks.
  • the gauge 580 which illustrates the detected leak rate, can assist in identifying and resolving leaks.
  • FIG. 6G illustrates an alarm resolved screen 600G according to some embodiments. Screen 600G can be displayed upon resolution of alarms detected by the therapy unit. Screen 600G can be displayed for a period of time and then be replaced by a therapy deliver screen. The alarm may be silenced.
  • any of the screens depicted in Figures 6A-6G may include additional or alternative controls, indicators, messages, icons, and the like.
  • additional or alternative screens may be used for alerting the user to one or more alarms.
  • a canister such as the canister 220
  • a canister 220 is made out of plastic or another type of material that may deform under application of sufficiently high vacuum pressure. Such deformations may be undesirable as they may reduce the capacity of the canister and risk breakage and malfunction. While plastic material provides a multitude of advantages, such as being inexpensive, lightweight, easy to manufacture, and the like, it is beneficial to address the deformability of the material when sufficient vacuum pressure is applied to the wound by the pump assembly 230.
  • Figure 7A illustrates an 800 mL canister 700A with a reinforcement element or stiffener 710 according to some embodiments.
  • the stiffener 710 helps to reinforce the canister and to prevent collapsing of the canister 700A when sufficiently high vacuum pressure is applied to the wound.
  • the stiffener 710 is attached (e.g., sealed, glued, molded, etc.) to the front wall of the canister 700A (e.g., wall with volume gradations).
  • the stiffener can be attached to a location on the front wall different than that illustrated in Figure 7A or be attached to any suitable location on any wall other than the front wall.
  • Figure 7B illustrates another view of an 800 mL canister 700B that utilizes the stiffener 710.
  • the stiffener 710 is illustrated in Figure 7C.
  • the stiffener 710 has a base element 712 that is configured to be attached to the wall of the canister and a member or component 714 that protrudes or extends from the base element 712 toward the opposite wall when negative pressure is not being applied to the wound.
  • the component 714 may be long enough so that at least a part of the component contacts the opposite wall of the canister when negative pressure is not applied to the canister. Alternatively, the component 714 may come into contact the opposite wall when sufficient negative pressure is applied to the canister. As is illustrated, the component 714 extends at about a perpendicular angle from the base element 712. Alternatively, the component 714 can extend at any suitable angle.
  • the stiffener 710 may be small and lightweight.
  • the stiffener 710 may have one or more circular holes 716 of different (or same) diameter stamped in the component 714.
  • the one or more holes can make the stiffener 710 lighter.
  • the stiffener 710 may have one or more holes of any suitable shape, such as rectangular, triangular, elliptic, or any other regular or irregular shape. In case more than one hole is stamped, the holes may have similar shapes and dimensions or different shapes and/or dimensions.
  • the one or more voids can be stamped in the base element 712 and/or the component 714.
  • Figure 6C illustrates a rectangular base element 712 and a hexagonal component 714 are rectangular, the base element 712 and/or the component 714 may have any other suitable shape.
  • the dimensions and thickness of the stiffener as well as its geometry can be selected based on the geometry and capacity of the canister and negative pressure levels that the canister will be exposed to.
  • the length and height of the base element 712 can be about 1.71 inches and 1.37 inches respectively.
  • the length of the component 714 (along its longest dimension) can be about 1.57 inches and the height of the component 714 (along its tallest dimension) can be about 1.94 inches.
  • other suitable geometries and dimensions can be used.
  • stiffener such as the stiffener 710
  • more than one stiffener 710 can be utilized.
  • the stiffener 710 (or multiple stiffeners) can be attached to any suitable location on the back wall, side walls, and so on.
  • the stiffener 710 may not be used. Instead, for example, one or more ribs can be placed on the walls of the canister, the walls of the canister may be made thicker to prevent or resist collapsing or the walls may be made of stiffer material, etc.
  • the pump assembly controls the vacuum pump to deliver negative pressure therapy to a wound according to a selected or programmed protocol.
  • Pump control can be performed by the pump control processor 370 alone or in combination with the processor 310.
  • the user can select continuous operation at a desired pressure (or negative pressure setpoint).
  • the pump assembly can activate the vacuum pump to reduce or draw down the pressure at the wound (e.g., under the dressing) to reach the setpoint.
  • the drawdown can be performed by increasing the negative pressure at the wound limited by a maximum change in negative pressure per unit time called compression, until the setpoint has been achieved.
  • Wound drawdown can be defined as the period of time immediately after therapy has been initiated during which the wound has not yet achieved the setpoint. As explained below, at the end of this period when the setpoint is achieved, the flow rate in the fluid flow path should be below a leak (or high flow) threshold and above a low vacuum threshold, otherwise an appropriate alarm will be activated.
  • Figure 8 illustrates a process 800 for providing negative pressure wound therapy according to some embodiments.
  • the process 800 can be executed by the pump control processor 370 alone or in combination with the processor 310.
  • the process 800 can be periodically executed, such as for example every 100 milliseconds (or 10 times per second) or at any other suitable frequency. Alternatively or additionally, the process 800 can be continuously executed.
  • the process 800 can begin in block 802, which it can transition to when therapy is initiated or when the setpoint is changed while therapy is being delivered.
  • the process 800 compares wound pressure, which can be determined as explained below, to the setpoint. If the wound pressure is below the setpoint, the process 800 can transition to block 804. Conversely, if the wound pressure exceeds or is equal to the setpoint, the process 800 can transition to block 806.
  • the process 800 can increment a pump ramp setpoint by an amount that depends on the compression setting as explained below.
  • the vacuum pump will then attempt to draw down the wound pressure to reach the current value of the pump ramp setpoint.
  • a suitable pump drive signal such as voltage or current signal, can be generated and supplied to the pump motor so as to increase the speed of the pump motor to achieve wound draw down.
  • the pump motor can be driven using PWM or any other suitable method.
  • the process 800 can continue incrementing the pump ramp setpoint until it reaches the setpoint selected by the user.
  • the process 800 can transition to block 808 when the wound pressure has nearly reached or reached the setpoint.
  • the process 800 can transition to block 808 when the wound pressure is within a ramp up threshold pressure of the setpoint, such as within 2 mmHg of the setpoint or within any other suitable value.
  • the process 800 can set the pump ramp setpoint to the setpoint selected by the user.
  • the process 800 can deactivate the pump so that the wound pressure is allowed to decay, such as due to one or more leaks in the fluid flow path, to reach or almost reach the setpoint.
  • the process 800 can transition to block 808.
  • the process 800 can transition to block 808 when the wound pressure is within a ramp down threshold pressure of the setpoint, such as within 5 mmHg of the setpoint or within any other suitable value.
  • the ramp down threshold pressure can be the same as the ramp up threshold pressure.
  • the pump ramp setpoint can be set to the setpoint selected by the user.
  • the process 800 can control the vacuum pump to maintain the desired negative pressure at the wound.
  • One or more conditions, such as high vacuum, low vacuum, leak, and the like can be detected in block 808 as is explained below. If the user changes the setpoint to be more negative or more positive or if delivery of therapy is paused, the process 800 can transition to block 802.
  • the pump assembly controls the vacuum pump to draw down the wound (e.g., as is explained above in connection with block 804) by utilizing compression.
  • compression can be beneficial for avoiding rapid changes in wound pressure, which can minimize patient discomfort, reduce noise produced as a result of operating the pump, maintain efficient delivery of negative pressure, maintain efficient use of power (e.g., battery power), and the like.
  • Compression can be executed by the process 800, which in turn can be implemented by the pump control processor 370 alone or in combination with the processor 310.
  • Compression can correspond to the maximum desired increase in negative pressure at the wound per unit of time. Compression can be determined based on the negative pressure setpoint and selected compression setting (e.g., low, medium, or high) as explained above in connection with Figure 5F.
  • Compression can be utilized when the wound is expected to experience a significant increase in negative pressure. This can occur when: (1) therapy is initiated on a deflated wound, and negative pressure will increase from zero or substantially zero to reach the pressure setpoint at the wound; (2) therapy is active in intermittent mode and during transitions from a low negative pressure setpoint to a high negative pressure setpoint, negative pressure will increase to reach the higher pressure setpoint at the wound; (3) therapy is active and the setpoint has been changed to a more negative pressure value, which will cause negative pressure to be increased to reach the higher pressure setpoint at the wound.
  • compression may be utilized include, for example, when a leak is introduced after seal has been achieved, which can cause negative pressure at the wound to rapidly drop and the vacuum pump to increase or ramp up delivery of negative pressure in an attempt to maintain pressure. Once the leak has been corrected, the pump would attempt to rapidly restore setpoint pressure at the wound.
  • Compression can be achieved by maintaining a secondary negative pressure setpoint target that represents the negative pressure setpoint allowed by compression as a function of time.
  • the secondary setpoint can correspond to the pump ramp setpoint.
  • Secondary setpoint can be incremented based on the selected compression setting. Secondary setpoint can be incremented by a suitable amount every time process 800 is executed, such as 10 times a second or any other suitable frequency. For example, if low compression setting has been selected, the secondary setpoint can be incremented by -0.6 mmHg, which can result in negative pressure ramp up of no more than approximately -8 mmHg per second (assuming that pump rate is incremented 10 times a second, such as a result of executing the process 800).
  • the secondary setpoint can be incremented by -2 mmHg, which can result in negative pressure ramp up of no more than approximately -20 mmHg per second. If high compression setting has been selected, the secondary setpoint can be incremented by -4 mmHg, which can result is negative pressure ramp up of no more than approximately -40 mmHg per second. These values are illustrative and any other suitable values can be used.
  • the pump assembly monitors various parameters, such as pressure and rate of flow in the fluid flow path, in order to control the pump in connection with delivery of negative pressure wound therapy. Parameters monitoring and pump control can be performed by the pump control processor 370 alone or in combination with the processor 310. Monitoring the flow rate can be used, among other things, to ensure that therapy is properly delivered to the wound, to detect leakages, blockages, high pressure, and low vacuum, canister full, and the like.
  • the pump assembly can be configured to indirectly measure the flow rate in the fluid flow path.
  • the pump assembly can measure the speed (e.g., as frequency) of the vacuum pump motor by using a tachometer.
  • the pump assembly can measure a level of activity or duty cycle of the pump using any suitable approach, such as by monitoring voltage or current supplied to the pump, sensing pump speed (e.g., by using a Hall sensor), measuring back EMF generated by the pump motor, and the like.
  • Tachometer readings can be averaged in order to mitigate the effects of one or more errant readings. A number of most recent tachometer readings, such as over last 2.5 seconds or any other suitable time period, can be averaged to obtain short tachometer average.
  • a number of less recent tachometer readings can be averaged to obtain long tachometer average.
  • Short and long tachometer averages can be utilized for pump control.
  • the pump assembly can directly measure the flow rate, such as by using a flow meter.
  • Flow rate can be estimated as the air or gas volume moving over the wound per unit of time normalized to standard temperature and standard pressure (e.g., 1 atm). Flow rate can be periodically computed, such as every 250 milliseconds or any other suitable time value, according to the following formula:
  • Tachometer is short tachometer average (e.g., in Hz) and Slope and Intercept are constants that are based on the pressure setpoint.
  • the values for Slope and Intercept can be determined for possible pressure setpoints (e.g., -25 mmHg, -40 mmHg, -50 mmHg, -60 mmHg, -70 mmHg, -80 mmHg, -90 mmHg, -100 mmHg, -120 mmHg, -140 mmHg, -160 mmHg, -180 mmHg, -200 mmHg) for a given vacuum pump type.
  • possible pressure setpoints e.g., -25 mmHg, -40 mmHg, -50 mmHg, -60 mmHg, -70 mmHg, -80 mmHg, -90 mmHg, -100 mmHg, -120 mmHg,
  • the flow as a function of the pump speed may not be a best fit as a single line because the vacuum pump can be designed to be more efficient at lower flow rates. Because of this, slope and intercept values can be pre-computed for various setpoints and various pumps.
  • Flow rate can be measured in standard liters per minute (SLPM) or any other suitable measurement unit. As explained below, the determined flow rate can be compared to various flow rate thresholds, such as blockage threshold, leakage threshold, and maximum flow rate threshold, to determine a presence of a particular condition, such as a blockage, leakage, over vacuum, etc.
  • SLPM standard liters per minute
  • the pump assembly can determine and monitor pressure in the flow path using one or more sensors.
  • the pump assembly includes a pressure sensor in or near the inlet 252 (or canister connection) of the pump assembly 230. This pressure sensor can measure the pressure in the canister (or in or near the dressing in a canisterless system).
  • the pump assembly can continuously measure pressure in the canister, such as every millisecond or any other suitable duration. A suitable number of latest pressure sensor readings can be averaged to mitigate the effects of one or more errant readings.
  • Wound pressure can be estimated using the measured canister pressure and the pump speed. Because of presence of one or more leaks in the flow path, wound pressure may not be the same as canister pressure. For example, wound pressure may be lower or more positive than canister pressure. In some embodiments, wound pressure is estimated using the following formula:
  • Wound Pressure Canister Pressure– (Slope*Tachometer + Intercept)
  • Canister Pressure is averaged measured canister pressure.
  • Tachometer is short tachometer average and Slope and Intercept are constants that are based on the pressure setpoint. The values for Slope and Intercept are not necessarily same value as used above for determining the flow rate.
  • wound pressure can be measured directly by a pressure sensor placed in the wound or near the wound or under the dressing.
  • the pump assembly can monitor and detect various operating conditions. One or more of these conditions can be detected by the process 800 while the process in in block 808.
  • Blockage in the fluid flow path can be determined by comparing the flow rate, as reflected by long tachometer average, to a particular blockage threshold over or during a period of time, such as 2 minutes or any other suitable duration.
  • the blockage threshold can be selected or determined based on the particular pressure setpoint. That is, to detect blockage, the pump assembly can utilize a plurality of blockage thresholds corresponding to particular pressure setpoints.
  • the flow rate can be indirectly determined by detecting and monitoring the pump speed. Long tachometer average can be compared to the blockage threshold. Alternatively or additionally, short tachometer average or any other suitable measure of flow rate can be compared to the blockage threshold.
  • the pump assembly determines that there is a blockage in the fluid flow path and provides an indication (e.g., alarm screen). For example, to determine presence of a blockage, the pump assembly can determine whether the long tachometer average satisfies or exceeds the blockage threshold during a 2 minute period of time or during any other suitable period of time. Because long tachometer average may be updated at periodic time intervals due to periodic sampling of the tachometer, the pump assembly may compare the long tachometer average as it is being updated to the blockage threshold over the 2 minute period of time.
  • Blockage can be detected provided that each long tachometer average determined during the 2 minute interval satisfies or exceeds the blockage threshold. Alternatively or additionally, blockage can be detected if the majority of sampled long tachometer averages, such as 9 out of 10 or any other suitable number, satisfy or exceed the blockage threshold. Detected blockage may be cleared when the long tachometer average falls below the blockage threshold for a period of time, such as 5 seconds or any other suitable duration. Blockage detection may be suspended while the process 800 is in block 806.
  • blockage can be detected by determining whether the pressure level at the wound is decreasing or decaying as expected. For example, the drop in pressure at the wound can be computed over a period of time, such as 30 seconds or any other suitable duration. A blockage may be present if the wound pressure at the end of the period of time has not decreased to satisfy (e.g., exceed) a pressure decay threshold.
  • the pump assembly can detect and provide indication of a low vacuum condition by determining whether the canister pressure satisfies (e.g., falls below or is more positive than) a low vacuum pressure threshold during a period of time, such as 30 seconds or any other suitable duration.
  • the low vacuum pressure threshold can be selected or determined based on the pressure setpoint. Low vacuum detection may be suspended while the process 800 is in block 806. Detected low vacuum can be cleared when the canister pressure exceeds the low vacuum pressure threshold for a period of time, such as 5 seconds or any other suitable value. Alternatively or additionally, the pump assembly can compare the measured wound pressure with the low vacuum pressure threshold.
  • the pump assembly can detect and provide indication of a high vacuum condition by determining whether the canister pressure satisfies (e.g., exceeds) a particular high vacuum pressure threshold during a period of time, such as 30 seconds or any other suitable duration.
  • the high vacuum pressure threshold can be selected or determined based on the pressure setpoint.
  • High vacuum detection may be suspended while the process 800 is in block 806. Detected high vacuum may be cleared by power cycling the pump assembly or by another other suitable means, such as by determining that the canister pressure falls below the high vacuum pressure threshold for a period of time, such as 5 seconds or any other suitable duration.
  • the pump assembly can compare the measured wound pressure with the high vacuum pressure threshold.
  • the pump assembly can detect and provide indication of an over vacuum (or excessive vacuum) condition by determining whether the canister pressure satisfies (e.g., exceeds) an over vacuum threshold, such as -250 mmHg or any other suitable value, during a period of time, such as 2 seconds or any other duration. Detected over vacuum may be cleared by power cycling the pump assembly or by another other suitable means, such as by determining that the canister pressure falls below the over vacuum pressure threshold for a period of time, such as 5 seconds or any other suitable duration. Alternatively or additionally, the pump assembly can compare the wound pressure with the over vacuum threshold.
  • an over vacuum threshold such as -250 mmHg or any other suitable value
  • the pump assembly can detect and provide indication of a leak condition by determining whether the short tachometer average satisfies a leak threshold during a period of time, such as 2 minutes or any other suitable duration.
  • the leak threshold can be selected or determined based on the pressure setpoint. For example, the pump assembly can determine whether the short tachometer average exceeds the leak threshold over a 2 minute period as the vacuum pump is attempting to reach and/or maintain the desired setpoint in the presence of one or more leaks. Alternatively or additionally, the pump assembly can compare the long tachometer average with the leak threshold. Leak detection may be suspended while the process 800 is in block 806.
  • Detected leak may be cleared when the short tachometer average falls below the leak threshold for a period of time, such as 5 seconds or any other suitable duration.
  • a period of time such as 5 seconds or any other suitable duration.
  • long tachometer average or any other suitable measure of flow rate can be compared to the leak threshold.
  • the pump assembly can detect and provide indication of a canister full condition. This determination can be made in when the process 800 is in block 808. First, the pump assembly can determine whether the short tachometer average is below the leak threshold and the canister pressure exceeds (or is more negative than) the low vacuum pressure threshold. As is indicated by the short tachometer average being below the leak threshold, there are leak or leaks in the fluid flow path while there is no low vacuum condition detected, as is indicated by canister pressure being above the low vacuum pressure threshold (e.g., canister pressure is normal).
  • the determination of canister pressure remaining at a normal level while presence of a significant leak in the fluid flow path has been detected provides an indication that the canister may be full (e.g., canister filter may be blocked).
  • determination of whether the canister if full is performed based at least in part on measuring characteristics of pressure pulses or signals in the fluid flow path.
  • the pump generates pressure pulses or signals that are propagated through the fluid flow path.
  • the pressure signals which can be detected by a pressure sensor, are illustrated by the pressure curve 902 of Figure 9 according to some embodiments.
  • pressure in the fluid flow path varies or oscillates around a particular pressure setpoint 908 during normal operation of the system.
  • Region 906 illustrates pressure pulses in the flow path in presence of a blockage distal to the pump. For example, the canister (or dressing) becomes full and/or a canister (or dressing) filter is occluded or blocked.
  • region 906 presence of a distal blockage causes a reduced volume to be seen upstream of the canister (or dressing), and the amplitude of the pressure pulses changes (e.g., increases).
  • the frequency of a pressure signal also changes (e.g., slows down or decreases).
  • Changes in the amplitude of the pressure signal can be measured using a variety of techniques, such as by measuring peak-to-trough change.
  • the changes in the pressure pulse signal can be magnified or enhanced by varying the pump speed, varying the cadence of the pump, such as by adjusting PWM parameters, and the like.
  • Such adjustments of pump operation are not required but can be performed over short time duration and the changes can be small such that the operation of the system remains relatively unaffected.
  • detectuin of a dressing full condition or dressing filter (which may be hydrophobic) occluded condition can be an equivalent to detection of canister full condition.
  • Canister full condition can be detected by collecting a plurality of pressure sensor readings, each performed over a time duration (e.g., 2 seconds or any other suitable duration which may be vary between sample periods), are collected. A number of readings of the plurality of readings, such as 25 sample periods out of 30 or any other suitable number, are checked to determine if each indicates that the canister is full. This can performed by determining maximum and minimum pressure values captured over the time duration of a particular sample period. The values can be voltage values, current values, or any other suitable values that correspond to pressure. A difference between maximum and minimum values for a particular sample period corresponds to peak-to-through pressure (which is indicative of change in pressure pulse amplitude).
  • a time duration e.g., 2 seconds or any other suitable duration which may be vary between sample periods
  • the threshold value can be any suitable pressure threshold, such as a value selected or determined based on the negative pressure setpoint and the current level of activity of the pump, which as explained above can be determined using short tachometer average (or long tachometer average or any other suitable measure of flow rate).
  • threshold values listed in Table 1 can be used for comparing to peak-to-through pressure. These values correspond to a particular pump motor and particular pressure sensor.
  • Canister full determination can be performed on a sliding window basis. For example, a sliding window of 25 out of 30 sample periods can be analyzed and if 25 sample periods are determined to indicate that the canister is full, the pump concludes that the canister (or dressing) is full. Assuming that the sample period is 2 seconds, using a sliding window of 25 out of 30 sample periods effectively results in determining whether change in pressure pulse amplitude exceeds the threshold for 60 seconds. If short tachometer average becomes greater than the leak threshold or canister pressure becomes less than the low vacuum pressure threshold, canister full detection can be suspended or terminated.
  • 60 second timer for canister full detection can be reset when it has been determined that short tachometer average becomes greater than the leak threshold or canister pressure becomes less than the low vacuum pressure threshold. This can prevent generation of unnecessary and undesirable alarms.
  • canister full condition can be detected if a single sample period indicates that the canister is full.
  • performing canister full detection using a plurality of sample periods can mitigate the effects of one or more transient conditions in the fluid flow path or one or more errant pressure readings.
  • canister full detection can be performed by measuring the frequency of detected pressure signal and comparing the measured frequency to one or more suitable thresholds.
  • the pump assembly can perform leak check test, which may result in detection of a leak or low vacuum. If at any point during a time period that follows initiation of therapy, such as 45 seconds or any other suitable duration after therapy has been started, the short tachometer average rate falls below the leak threshold and process 800 has transitioned to block 808 (steady state), the leak check test has passed and suitable seal is deemed to have been achieved.
  • the fluid flow path is suitably sealed and no significant leaks are present (e.g., the dressing has been properly placed and proper connections between pump assembly, canister, and dressing have been made).
  • the short tachometer average remains above the leak threshold at the end of the period of time, a leak is likely to be present, and the pump assembly indicates presence of a leak.
  • the pump assembly determines whether the canister pressure satisfies or is above the low vacuum pressure threshold and the short tachometer average is below the leak threshold. If both of these conditions are met, it is determined that the fluid flow path is suitably sealed and no significant leaks are present. That is, even though the process 800 has not yet transitioned to block 808, which indicates that the setpoint has been reached or substantially reached, the pump is properly working toward establishing the negative pressure setpoint at the wound as is evidenced by the flow rate remaining below the leak threshold and the vacuum level remaining above the low vacuum threshold.
  • the pump assembly Conversely, if the flow rate satisfies or exceeds the leak threshold, a leak is likely to be present, and the pump assembly indicates presence of a leak. If the low vacuum threshold is satisfied, the pump assembly indicates a low vacuum condition. Alternatively or additionally, long tachometer average or any other suitable measure of flow rate can be compared to the blockage threshold.
  • leak check test After leak check test has passed, a suitable seal can be deemed to have been achieved until therapy is paused. After therapy is restarted, leak check test can be performed.
  • selecting or activating Y-connect feature for treatment of multiple wounds, can alter or modify detection of one or more conditions, such as blockages, leaks, canister full condition, and the like.
  • Activating the Y- connect feature can adjust one or more of various thresholds described above. For example, activating the Y-connect feature can decrease sensitivity of blockage detection by increasing the blockage threshold, which is used for blockage detection as explained above. The blockage threshold can be increased by a suitable amount, such as doubled.
  • multiple pressure sensors can be placed in the fluid flow path to facilitate detection of one or more of the above-described conditions.
  • a pressure sensor can be placed in the wound or under the dressing to directly determine the wound pressure. Measuring pressure at different locations in the fluid flow path, such as in the canister and at the wound, can facilitate detection of blockages, leaks, canister full condition, and the like.
  • Multiple lumens can be utilized for connecting fluid flow path elements, such as pressure sensors, canister, pump assembly, dressing, and the like.
  • Canister full condition can be detected by placing a sensor, such as capacitive sensor, in the canister.
  • the maximum pressure supplied by the pump can be limited mechanically or electrically.
  • a pump drive signal such as voltage or current supplied to the pump, can be limited not exceed a maximum flow rate threshold, such as 1.6 liters/min or any other suitable value. Additional details of flow rate detection and pump control are provided in U.S. Patent Publication No.2013/0150813, which is incorporated by reference in its entirety.
  • one or more flow sensors and/or flow meters can be used to directly measure the fluid flow.
  • the pump assembly can utilize one or more of the above-described techniques in parallel to control the pump and to detect various conditions.
  • the pump assembly can be configured to suitably arbitrate between using parameters determined by different techniques. For example, the pump assembly can arbitrate between flow rates determined indirectly, such as based on the pump speed as measured by a tachometer, and directly, such as by using a flow meter. In certain embodiments, the pump assembly can indirectly determine the flow rate and resort to direct determination of the flow rate when needed, such as when indirectly determined flow rate is perceived to be inaccurate or unreliable. Location Monitoring
  • the provider or manufacturer of TNP or reduced pressure therapy systems can desire to bill for the possession or usage of pump assemblies.
  • the process of accounting for possession or use of the pump assemblies can be difficult for the provider to manage since the provider may not have control over the administration and distribution of the pump assemblies.
  • the provider may rely on other parties, such as hospital staff, to accurately track the possession or use of the pump assemblies.
  • the other parties may not at times accurately track the possession or use of the pump assemblies, so the provider may rely on erroneous or incomplete information from the other parties when accounting for and subsequently billing for the usage of pump assemblies. This situation can risk over or under billing for use of the pump assemblies.
  • disclosed systems and methods can assist the provider of pump assemblies in accurately monitoring and tracking the pump assemblies to account for possession or use of the pump assemblies.
  • FIG. 10 illustrates a system 1000 for monitoring the locations of pump assemblies according to some embodiments.
  • the system 1000 includes multiple pump assemblies 230 and a location monitoring hub 1010.
  • the multiple pump assemblies 230 can each be an instance of the pump assembly 230 described with respect to Figures 2A-2C.
  • the location monitoring hub 1010 can communicate with the multiple pump assemblies 230 to individually monitor the locations of the multiple pump assemblies 230. Based on the determined locations of the multiple pump assemblies 230, the location monitoring hub 1010 can automatically determine whether the multiple pump assemblies 230 may be within a proximity or a coverage area of the location monitoring hub 1010 and thereby control inventory management related to the multiple pump assemblies 230, such as in connection with billing for the use of the multiple pump assemblies 230.
  • the location monitoring hub 1010 can utilize one or more of the following types of connections: cellular connectivity (for example, 2G, 3G, LTE, 4G, GPRS), WiFi TM connectivity, WLAN connectivity, Internet connectivity, Bluetooth TM connectivity, ZigBee connectivity, and the like.
  • cellular connectivity for example, 2G, 3G, LTE, 4G, GPRS
  • WiFi TM connectivity for example, WiFi TM connectivity
  • WLAN connectivity for example, Wi-Fi TM connectivity
  • Internet connectivity for example, Wi-Fi TM connectivity
  • Bluetooth TM connectivity for example, Wi-Fi TM connectivity
  • ZigBee connectivity ZigBee connectivity
  • Individual pump assemblies of the multiple pump assemblies 230 can repeatedly communicate with the location monitoring hub 1010 to repeatedly indicate to the location monitoring hub 1010 whether the multiple pump assemblies 230 may be present in the proximity of the location monitoring hub 1010.
  • the pump assembly A can, for instance, transmit a signal using a Bluetooth TM protocol communication to the location monitoring hub 1010 on a periodic, random, or scheduled basis (for instance, every 1, 5, or 20 seconds) and the like indicating that the pump assembly A may be in the proximity of the location monitoring hub 1010.
  • the pump assembly A can transmit the signal with a frequency based at least on a minimum billing period of the pump assembly A, such that the pump assembly A transmits the signal at least once per minimum billing period.
  • the pump assembly A can transmit the signal with a 30 minute periodicity.
  • the location monitoring hub 1010 can, in turn, use the received signal from the pump assembly A to determine that the pump assembly A is present in the proximity of the location monitoring hub 1010.
  • the location monitoring hub 1010 can also use the received signal to determine the change in location over time of the pump assembly A relative to the location monitoring hub 1010.
  • the location monitoring hub 1010 can determine the location of individual pump assemblies of the multiple pump assemblies 230 over time. In one example, the location monitoring hub 1010 can determine the location of an individual pump assembly, such as the pump assembly A, based at least on whether the location monitoring hub 1010 received a communication from the individual pump assembly recently (for example, within a threshold period of time). When a communication has not been received recently, the location monitoring hub 1010 can conclude or establish that the individual pump assembly is not within the proximity of the location monitoring hub 1010. In such cases, the location monitoring hub 1010 may receive additional communications or information from the individual pump assembly indicating whether further communication may not be received for other reasons, such as if a low battery condition at the individual pump assembly may cause the individual pump assembly to shut down and cease communications.
  • an individual pump assembly such as the pump assembly A
  • the additional communications or information can be used by the location monitoring hub 1010 to also indicate to send out an engineer to repair or replace the individual pump assembly.
  • the location monitoring hub 1010 can determine the location of an individual pump assembly, such as the pump assembly B, based at least on the signal strength of a received communication from the individual pump assembly at the location monitoring hub 1010. As the signal strength of the received communication diminishes, the location monitoring hub 1010 can determine that the individual pump assembly is farther from the location monitoring hub 1010.
  • the location monitoring hub 1010 can include two or more antennas usable to receive communications from the multiple pump assemblies 230, enabling the signal strength at the individual antennas to be used to more precisely determine (for example, triangulate) the locations of the multiple pump assemblies 230.
  • the location monitoring hub 1010 can perform or facilitate inventory management functions for the multiple pump assemblies 230 based on the coverage area for the location monitoring hub 1010.
  • the coverage area can be a geographical area being monitored by the location monitoring hub 1010, which can be used to make decisions about the status of the multiple pump assemblies 230.
  • the coverage area of the location monitoring hub 1010 can correspond to the boundaries of a medical device storage facility, such as a storage closet in a hospital.
  • the location monitoring hub 1010 can further facilitate management of inventory levels across different coverage areas. For example, if most or all of the pump assemblies in a particular coverage area may have been removed for use, the location monitoring hub 1010 can automatically indicate to send additional pump assemblies to the particular coverage area. Alternatively, if a number of pump assemblies in a certain coverage area may remain unused for an extended period of time, the location monitoring hub 1010 can automatically indicate to redistribute some of the pump assemblies in the certain coverage area to another coverage area.
  • the coverage area can be an area around the location monitoring hub 1010, such as an area defined by any location within a certain distance from the location monitoring hub 1010.
  • the coverage area can be circular or spherical with the location monitoring hub 1010 positioned at the center.
  • the coverage area can be a non-circular or asymmetrical area located around the location monitoring hub 1010 or some area monitored by the location monitoring hub 1010 but not located around or near the location monitoring hub 1010.
  • the coverage area can be in part defined by a two- or three-dimensional region, such as a floor space area, which has an area, for example, of around 100 m 2 , 500 m 2 , or 1000 m 2 , and the like. This can provide for geo-fencing capabilities.
  • the size or position of the coverage area can be controlled or set by the location monitoring hub 1010 in some implementations.
  • a manager of the location monitoring hub 1010 can input a desired size of the coverage area, and the location monitoring hub 1010 can provide a coverage area having the desired size.
  • the boundaries of the coverage area can depend on the range over which the location monitoring hub 1010 can successfully communicate with the multiple pump assemblies 230. For instance, the range over which the location monitoring hub 1010 can communicate with an individual pump assembly may define the coverage area for the location monitoring hub 1010.
  • the range can, for example, be (1) a range over which the location monitoring hub 1010 can receive communications from the multiple pump assemblies 230 without errors or (2) a range over which the location monitoring hub 1010 can receive communications having a signal strength that exceeds a signal strength threshold.
  • the location monitoring hub 1010 can monitor the locations of the multiple pump assemblies 230 relative to the coverage area over time and thus be used to indicate whether to bill for the multiple pump assemblies 230.
  • the location monitoring hub 1010 can be placed in a hospital storage area (for example, a storage closet or room) used for storing available-for-use pump assemblies, such as the pump assemblies C, E, and F.
  • the coverage area can span the hospital storage area so that the location monitoring hub 1010 determines whether the multiple pump assemblies 230 are within or outside the hospital storage area.
  • a pump assembly such as the pump assembly A, B, or D
  • the location monitoring hub 1010 can infer that the pump assembly is being used for delivery of therapy to a patient such that the location monitoring hub 1010 can indicate to begin billing for the removed pump assembly.
  • this indication can be provided to a remote computer 1020 over any suitable network, such as the Internet.
  • the remote computer 1020 can be a billing system.
  • This indication can also be provided to the remote computer 1020.
  • the location monitoring hub 1010 can provide accurate indications of when to begin and stop billing for an individual pump assembly according at least to a comparison of when the individual pump assembly may have been removed from and returned to the hospital storage area.
  • the indications can be provided using any suitable communication interface, such as by using iCloud technology. This can facilitate accurate tracking of usage and allow for accurate billing for delivery of negative pressure wound therapy, which in turn can facilitate accurate reimbursements from insurers.
  • the system 1000 can further be used to provide one or more checks to determine whether to bill for an individual pump assembly. For example, if an individual pump assembly is removed from and returned to the coverage area within a relatively short time (for example, within a time of less than 10 minutes), the removal and return timings for the individual pump assembly may be used to decide not to provide an indication to bill for the removal of the individual pump assembly.
  • the location monitoring hub 1010 can store an indication of whether a determined location for an individual pump assembly may be erroneous (for instance, a communicated message from the individual pump assembly may specify a location for the individual pump assembly different from the location of the individual pump assembly determined by the location monitoring hub 1010), and thus may indicate not to bill for the individual pump assembly.
  • an individual pump assembly can itself track timings or periods that the individual pump assembly may be outside the coverage area, and the timings or periods tracked by the individual pump assembly can be compared to the timings or time periods indicated by the location monitoring hub 1010 for consistency. Moreover, other timings or periods tracked by an individual pump assembly (for instance, total therapy deliver time, device on time, activity timings in an activity log, and the like) can be compared to the timings or time period indicated by the location monitoring hub 1010 to determine whether and when to bill for the individual pump assembly.
  • the location monitoring hub 1010 may be omitted as the individual pump assemblies can be configured to communicate directly with the remote computer 1020 via the network.
  • an individual pump assembly can provide its location directly to the remote computer 1020 using the communications processor 330.
  • the remote computer 1020 can then determine whether the individual pump assembly may be within a coverage area based at least on the provided location.
  • an indication or to indicate can, in addition to having its ordinary meaning, respectively refer to a message or sending of a message via a communication channel (for instance, wired, wireless, electromagnetic, or magnetic mediums and the like) to point out information.
  • the message can include data sufficient for a receiver of the message to determine the information pointed out in the message.
  • the message or information pointed out in the message can cause the receiver or a device associated with the receiver to perform an action in accordance with the information pointed out in the message.
  • any value of a threshold, limit, duration, etc. provided herein is not intended to be absolute and, thereby, can be approximate.
  • any threshold, limit, duration, etc. provided herein can be fixed or varied either automatically or by a user.
  • relative terminology such as exceeds, greater than, less than, etc. in relation to a reference value is intended to also encompass being equal to the reference value. For example, exceeding a reference value that is positive can encompass being equal to or greater than the reference value.
  • relative terminology such as exceeds, greater than, less than, etc. in relation to a reference value is intended to also encompass an inverse of the disclosed relationship, such as below, less than, greater than, etc. in relations to the reference value.
  • the various components illustrated in the figures may be implemented as software and/or firmware on a processor, controller, ASIC, FPGA, and/or dedicated hardware.
  • Hardware components such as processors, ASICs, FPGAs, and the like, can include logic circuitry.
  • User interface screens illustrated and described herein can include additional and/or alternative components. These components can include menus, lists, buttons, text boxes, labels, radio buttons, scroll bars, sliders, checkboxes, combo boxes, status bars, dialog boxes, windows, and the like. User interface screens can include additional and/or alternative information. Components can be arranged, grouped, displayed in any suitable order.

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AU2014402290A AU2014402290B2 (en) 2014-07-31 2014-11-19 Systems and methods for applying reduced pressure therapy
EP19209497.7A EP3659638A1 (en) 2014-07-31 2014-11-19 Systems and methods for applying reduced pressure therapy
JP2017505135A JP6644764B2 (ja) 2014-07-31 2014-11-19 減圧療法を施すためのシステムおよび方法
EP14815987.4A EP3174569B1 (en) 2014-07-31 2014-11-19 Systems and methods for applying reduced pressure therapy
US15/500,495 US10744239B2 (en) 2014-07-31 2014-11-19 Leak detection in negative pressure wound therapy system
BR112017001969A BR112017001969A2 (pt) 2014-07-31 2014-11-19 sistemas e métodos para aplicação de uma terapia de pressão reduzida
CA2956572A CA2956572C (en) 2014-07-31 2014-11-19 Systems and methods for applying reduced pressure therapy
CN201480082413.7A CN106687154B (zh) 2014-07-31 2014-11-19 用于施用减压治疗的系统和方法
US15/443,555 US20170165405A1 (en) 2014-07-31 2017-02-27 Systems and methods for applying reduced pressure therapy
US16/834,189 US12133789B2 (en) 2014-07-31 2020-03-30 Reduced pressure therapy apparatus construction and control
US16/994,182 US12115298B2 (en) 2014-07-31 2020-08-14 Wound pressure determination for reduced pressure wound therapy
US18/908,652 US20250025349A1 (en) 2014-07-31 2024-10-07 Reduced pressure therapy apparatus construction and control

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US62/031,704 2014-07-31

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US15/443,555 Division US20170165405A1 (en) 2014-07-31 2017-02-27 Systems and methods for applying reduced pressure therapy
US16/834,189 Continuation-In-Part US12133789B2 (en) 2014-07-31 2020-03-30 Reduced pressure therapy apparatus construction and control
US16/994,182 Continuation US12115298B2 (en) 2014-07-31 2020-08-14 Wound pressure determination for reduced pressure wound therapy

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