WO2009057693A1 - マイクロチップ、マイクロチップデバイス及びマイクロチップを用いた蒸発操作方法 - Google Patents

マイクロチップ、マイクロチップデバイス及びマイクロチップを用いた蒸発操作方法 Download PDF

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Publication number
WO2009057693A1
WO2009057693A1 PCT/JP2008/069755 JP2008069755W WO2009057693A1 WO 2009057693 A1 WO2009057693 A1 WO 2009057693A1 JP 2008069755 W JP2008069755 W JP 2008069755W WO 2009057693 A1 WO2009057693 A1 WO 2009057693A1
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WO
WIPO (PCT)
Prior art keywords
micro chip
liquid phase
channel
pool portion
micro
Prior art date
Application number
PCT/JP2008/069755
Other languages
English (en)
French (fr)
Inventor
Katsuhiko Ohsaki
Shigeki Yamazaki
Takehiko Kitamori
Masaharu Ueno
Kazuma Mawatari
Yoshikuni Kikutani
Original Assignee
Jfe Engineering Corporation
Kanagawa Academy Of Science And Technology
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Jfe Engineering Corporation, Kanagawa Academy Of Science And Technology filed Critical Jfe Engineering Corporation
Priority to EP08845767.6A priority Critical patent/EP2218499B1/en
Priority to US12/734,384 priority patent/US9120032B2/en
Publication of WO2009057693A1 publication Critical patent/WO2009057693A1/ja

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Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D1/00—Evaporating
    • B01D1/0082—Regulation; Control
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D1/00—Evaporating
    • B01D1/14—Evaporating with heated gases or vapours or liquids in contact with the liquid
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D1/00—Evaporating
    • B01D1/22—Evaporating by bringing a thin layer of the liquid into contact with a heated surface
    • B01D1/221—Composite plate evaporators
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J19/0093—Microreactors, e.g. miniaturised or microfabricated reactors
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00781—Aspects relating to microreactors
    • B01J2219/00819—Materials of construction
    • B01J2219/00837—Materials of construction comprising coatings other than catalytically active coatings
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00781—Aspects relating to microreactors
    • B01J2219/00873—Heat exchange
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0678—Facilitating or initiating evaporation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/16—Surface properties and coatings
    • B01L2300/161—Control and use of surface tension forces, e.g. hydrophobic, hydrophilic
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0406—Moving fluids with specific forces or mechanical means specific forces capillary forces
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0466—Evaporation to induce underpressure
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip

Landscapes

  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Micromachines (AREA)
  • Nuclear Medicine (AREA)
  • Vaporization, Distillation, Condensation, Sublimation, And Cold Traps (AREA)

Abstract

　液相の蒸発操作をマイクロチップ上の操作として集積化できるマイクロチップを提供する。内部に気相の流路１３を有するマイクロチップ１０において、流路１３の底部のプール部１２に毛管力を利用して液相を分散させると共に、分散させた液相を溜め、プール部１２に溜められた液相の少なくとも一部を蒸発させる。毛管力を利用することで、マイクロチップ１０内の流路１３の底部のプール部１２に液相を分散させ、溜めることができる。しかも、蒸発操作のために流路１３に気相を流したり、流路を真空引きしたりしても、プール部１２に溜まった液相が表面張力によってプール部１２にとどまる。このため、マイクロチップ１０内での高効率での蒸発操作が実現できる。
PCT/JP2008/069755 2007-11-01 2008-10-30 マイクロチップ、マイクロチップデバイス及びマイクロチップを用いた蒸発操作方法 WO2009057693A1 (ja)

Priority Applications (2)

Application Number Priority Date Filing Date Title
EP08845767.6A EP2218499B1 (en) 2007-11-01 2008-10-30 Micro chip, micro chip device, and evaporation operation method using the micro chip
US12/734,384 US9120032B2 (en) 2007-11-01 2008-10-30 Microchip, microchip device, and evaporation operation method using the microchip

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2007-285012 2007-11-01
JP2007285012A JP5309312B2 (ja) 2007-11-01 2007-11-01 マイクロチップ、マイクロチップデバイス及びマイクロチップを用いた蒸発操作方法

Publications (1)

Publication Number Publication Date
WO2009057693A1 true WO2009057693A1 (ja) 2009-05-07

Family

ID=40591077

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2008/069755 WO2009057693A1 (ja) 2007-11-01 2008-10-30 マイクロチップ、マイクロチップデバイス及びマイクロチップを用いた蒸発操作方法

Country Status (4)

Country Link
US (1) US9120032B2 (ja)
EP (1) EP2218499B1 (ja)
JP (1) JP5309312B2 (ja)
WO (1) WO2009057693A1 (ja)

Cited By (6)

* Cited by examiner, † Cited by third party
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JP2010260799A (ja) * 2009-04-30 2010-11-18 Jfe Engineering Corp マイクロチップを用いたｐｅｔ用標識化合物の製造方法及び装置
JP2012229968A (ja) * 2011-04-26 2012-11-22 Jfe Technos Corp マイクロチップユニット及びマイクロチップユニットを用いた化合物の合成装置
WO2012169108A1 (ja) * 2011-06-06 2012-12-13 パナソニック株式会社 ピロリン酸の測定方法およびｓｎｐタイピング方法
JP2013154336A (ja) * 2012-02-01 2013-08-15 Ckd Corp 液体制御装置
WO2016174769A1 (ja) * 2015-04-30 2016-11-03 株式会社日立製作所 溶媒置換装置及び溶媒置換方法
CN109771982A (zh) * 2019-02-25 2019-05-21 江苏沃德凯环保科技有限公司 一种防止蒸馏结垢的方法及装置

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JP5438351B2 (ja) * 2009-03-30 2014-03-12 Ｊｆｅテクノス株式会社 マイクロチップを用いたｐｅｔ用標識化合物の調剤方法及び装置
JP5431764B2 (ja) * 2009-03-30 2014-03-05 Ｊｆｅテクノス株式会社 マイクロチップを用いたフッ素ｆ−１８標識化合物の製造方法及び装置
JP5685630B2 (ja) * 2013-07-19 2015-03-18 Ｊｆｅエンジニアリング株式会社 マイクロチップ
TWI522174B (zh) * 2014-01-29 2016-02-21 國立屏東科技大學 微流體蒸氣蒸餾晶片
US10473668B2 (en) * 2014-06-06 2019-11-12 The Regents Of The University Of California Self-shielded, benchtop radio chemistry system with a plurality shielded carriers containing a disposable chip cassette
KR20180135058A (ko) 2016-04-28 2018-12-19 가부시키가이샤 아이에이치아이 분리 장치
JP7063541B2 (ja) * 2017-03-31 2022-05-09 住友理工株式会社 流体デバイス用シリコーン部材およびその製造方法
FR3131222A1 (fr) * 2021-12-23 2023-06-30 Centre National De La Recherche Scientifique Dispositif de séparation d’un mélange de fluides par distillation microfluidique

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Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010260799A (ja) * 2009-04-30 2010-11-18 Jfe Engineering Corp マイクロチップを用いたｐｅｔ用標識化合物の製造方法及び装置
JP2012229968A (ja) * 2011-04-26 2012-11-22 Jfe Technos Corp マイクロチップユニット及びマイクロチップユニットを用いた化合物の合成装置
WO2012169108A1 (ja) * 2011-06-06 2012-12-13 パナソニック株式会社 ピロリン酸の測定方法およびｓｎｐタイピング方法
JP5193396B2 (ja) * 2011-06-06 2013-05-08 パナソニック株式会社 ピロリン酸の測定方法およびｓｎｐタイピング方法
JP2013154336A (ja) * 2012-02-01 2013-08-15 Ckd Corp 液体制御装置
WO2016174769A1 (ja) * 2015-04-30 2016-11-03 株式会社日立製作所 溶媒置換装置及び溶媒置換方法
CN109771982A (zh) * 2019-02-25 2019-05-21 江苏沃德凯环保科技有限公司 一种防止蒸馏结垢的方法及装置
CN109771982B (zh) * 2019-02-25 2023-09-22 江苏沃德凯环保科技有限公司 一种防止蒸馏结垢的方法及装置

Also Published As

Publication number Publication date
EP2218499B1 (en) 2018-07-18
JP5309312B2 (ja) 2013-10-09
EP2218499A1 (en) 2010-08-18
JP2009106916A (ja) 2009-05-21
US20100247429A1 (en) 2010-09-30
US9120032B2 (en) 2015-09-01
EP2218499A4 (en) 2015-07-22

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