WO2008139786A1 - 微細針ディバイス及びその製造方法 - Google Patents

微細針ディバイス及びその製造方法 Download PDF

Info

Publication number
WO2008139786A1
WO2008139786A1 PCT/JP2008/056471 JP2008056471W WO2008139786A1 WO 2008139786 A1 WO2008139786 A1 WO 2008139786A1 JP 2008056471 W JP2008056471 W JP 2008056471W WO 2008139786 A1 WO2008139786 A1 WO 2008139786A1
Authority
WO
WIPO (PCT)
Prior art keywords
microneedle device
microneedles
skin surface
producing
same
Prior art date
Application number
PCT/JP2008/056471
Other languages
English (en)
French (fr)
Inventor
Ying-Shu Quan
Fumio Kamiyama
Yoshikazu Tobinaga
Tomoya Kitagawa
Kentaro Ohshima
Akira Yamamoto
Original Assignee
Cosmed Pharmaceutical Co., Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cosmed Pharmaceutical Co., Ltd. filed Critical Cosmed Pharmaceutical Co., Ltd.
Priority to KR1020097023674A priority Critical patent/KR101400545B1/ko
Priority to CN2008800150482A priority patent/CN101687090B/zh
Priority to US12/599,860 priority patent/US8167852B2/en
Publication of WO2008139786A1 publication Critical patent/WO2008139786A1/ja

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0046—Solid microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0053—Methods for producing microneedles
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T83/00—Cutting
    • Y10T83/04—Processes
    • Y10T83/0448—With subsequent handling [i.e., of product]
    • Y10T83/0467—By separating products from each other

Abstract

　皮膚表面内に容易に刺入でき、皮膚表面内において溶解又は膨潤する微細針を有する微細針ディバイスを提供する。 　微細針ディバイスは、基盤と、基盤上に配置された円錐状または多角錐状の皮膚表面内挿入用微細針とを備えている。皮膚表面内挿入用微細針は、キトサン、コラーゲン、ゼラチン及びヒアルロン酸よりなる群から選ばれた１種または複数種類の生体由来物質を５０重量％以上含有し、生体内で溶解又は膨潤しうる素材からなる。  
PCT/JP2008/056471 2007-05-15 2008-04-01 微細針ディバイス及びその製造方法 WO2008139786A1 (ja)

Priority Applications (3)

Application Number Priority Date Filing Date Title
KR1020097023674A KR101400545B1 (ko) 2007-05-15 2008-04-01 마이크로니들 디바이스 및 그의 제조 방법
CN2008800150482A CN101687090B (zh) 2007-05-15 2008-04-01 一种微针系统及其制造方法
US12/599,860 US8167852B2 (en) 2007-05-15 2008-04-01 Microneedle device and method for producing the same

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2007155752A JP2008284318A (ja) 2007-05-15 2007-05-15 生体由来物質からなる投薬用微細針
JP2007-155752 2007-05-15

Publications (1)

Publication Number Publication Date
WO2008139786A1 true WO2008139786A1 (ja) 2008-11-20

Family

ID=40002009

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2008/056471 WO2008139786A1 (ja) 2007-05-15 2008-04-01 微細針ディバイス及びその製造方法

Country Status (5)

Country Link
US (1) US8167852B2 (ja)
JP (1) JP2008284318A (ja)
KR (1) KR101400545B1 (ja)
CN (1) CN101687090B (ja)
WO (1) WO2008139786A1 (ja)

Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011002034A1 (ja) * 2009-07-01 2011-01-06 凸版印刷株式会社 針状体
CN109069812A (zh) * 2016-04-07 2018-12-21 实验室和人们 利用生物可吸收金属的微针
WO2020004428A1 (en) 2018-06-29 2020-01-02 L'oreal Cosmetic process using microneedle sheet
WO2020004666A1 (en) 2018-06-29 2020-01-02 L'oreal Cosmetic process using microneedle sheet
WO2020017441A1 (en) 2018-07-17 2020-01-23 L'oreal Microneedle sheet
US10603477B2 (en) 2014-03-28 2020-03-31 Allergan, Inc. Dissolvable microneedles for skin treatment
WO2020130157A1 (en) 2018-12-21 2020-06-25 L'oreal Kit and cosmetic process using microneedle sheet
EP3695876A1 (en) 2019-02-18 2020-08-19 L'oreal Pencil for inserting micro-implants inside upper skin layers
EP3698841A1 (en) 2019-02-19 2020-08-26 L'oreal Injection device
WO2020200407A1 (en) 2019-03-29 2020-10-08 L'oreal Frozen micro-implants and method of making same
US11065428B2 (en) 2017-02-17 2021-07-20 Allergan, Inc. Microneedle array with active ingredient

Families Citing this family (86)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8911749B2 (en) 2007-04-16 2014-12-16 Corium International, Inc. Vaccine delivery via microneedle arrays
EP2146689B1 (en) 2007-04-16 2020-08-12 Corium, Inc. Solvent-cast microneedle arrays containing active
JP2010141278A (ja) * 2008-12-10 2010-06-24 Yoshiichi Tobinaga 多糖質配線基板及びその製造方法
JP5499509B2 (ja) * 2009-04-02 2014-05-21 凸版印刷株式会社 針状物体の製造方法
CA2759850C (en) * 2009-04-24 2019-10-22 Corium International, Inc. Methods for manufacturing microprojection arrays
US8834423B2 (en) * 2009-10-23 2014-09-16 University of Pittsburgh—of the Commonwealth System of Higher Education Dissolvable microneedle arrays for transdermal delivery to human skin
KR101224939B1 (ko) 2009-12-07 2013-01-22 가천대학교 산학협력단 활성 성분의 흡수 속도가 개선된 마이크로니들
JP6327852B2 (ja) 2010-05-04 2018-05-23 コリウム インターナショナル， インコーポレイテッド 微小突起アレイを使用した副甲状腺ホルモンの経皮送達のための方法及びデバイス
CN102917752A (zh) * 2010-05-28 2013-02-06 久光制药株式会社 带微小突起的阵列
CN102917751A (zh) * 2010-05-28 2013-02-06 久光制药株式会社 具有带有微小突起的阵列的装置
US9763657B2 (en) 2010-07-21 2017-09-19 Mitraltech Ltd. Techniques for percutaneous mitral valve replacement and sealing
JP5672554B2 (ja) * 2010-08-19 2015-02-18 Ｊｃｒファーマ株式会社 皮下又は経皮吸収用組成物
JP5687170B2 (ja) 2011-03-30 2015-03-18 コスメディ製薬株式会社 マイクロニードルパッチ収納容器
CN102178616B (zh) * 2011-05-06 2013-06-05 广州保税区雅兰国际化妆品有限公司 一种玻尿酸微针贴膜及其制备方法
KR101990654B1 (ko) 2011-09-22 2019-06-18 코스메드 파마소티컬 씨오 쩜 엘티디 마이크로니들 패치 수납 용기
CN107582517A (zh) 2011-10-20 2018-01-16 考司美德制药株式会社 微针阵列
KR101635292B1 (ko) * 2011-10-28 2016-06-30 도판 인사츠 가부시키가이샤 중공 바늘 형상체의 제조 방법 및 중공 바늘 형상체
US20140371713A1 (en) * 2012-02-17 2014-12-18 Cosmed Pharmaceutical Co., Ltd. Short-time soluble microneedle
CN102580232B (zh) * 2012-02-23 2013-12-18 游学秋 一种丝素微针系统和丝素纳米颗粒及其制备方法
JP6277953B2 (ja) 2012-02-29 2018-02-14 凸版印刷株式会社 針状体の製造方法
MX370579B (es) 2012-05-01 2019-12-17 Univ Pittsburgh Commonwealth Sys Higher Education Arreglos de microagujas cargadas en la punta para insercion transdermica.
CN104379020A (zh) * 2012-06-29 2015-02-25 Elc管理有限责任公司 包含一种或多种化妆品成分的微针
AU2013280769A1 (en) * 2012-06-29 2015-01-22 Elc Management Llc Dissolvable microneedles comprising one or more encapsulated cosmetic ingredients
JP6546091B2 (ja) 2012-09-13 2019-07-17 アミール，アブラハム 皮膚増大（ｓｋｉｎａｕｇｍｅｎｔａｔｉｏｎ）のための送達デバイスおよび方法
KR101435888B1 (ko) * 2012-10-23 2014-09-01 연세대학교 산학협력단 히알루론산을 이용한 생분해성 마이크로니들 제조방법
KR102240354B1 (ko) 2012-11-02 2021-04-14 코스메드 파마소티컬 씨오 쩜 엘티디 레티노산 마이크로니들
CA2896188C (en) 2012-12-21 2021-02-23 Corium International, Inc. Microarray for delivery of therapeutic agent and methods of use
RU2679107C2 (ru) * 2013-01-21 2019-02-05 Пхэан Эстетикс Инк. Микроигла, форма для ее изготовления и способ изготовления микроиглы
US20200230033A1 (en) * 2013-01-21 2020-07-23 Paean Aesthetics Inc. Micro-spicule composition to control its shape and method for producing the same
US10245422B2 (en) 2013-03-12 2019-04-02 Corium International, Inc. Microprojection applicators and methods of use
AU2014233541B2 (en) 2013-03-15 2018-11-22 Corium Pharma Solutions, Inc. Microarray for delivery of therapeutic agent, methods of use, and methods of making
EP2968751B1 (en) 2013-03-15 2022-11-30 Corium, Inc. Multiple impact microprojection applicators
CA2906541C (en) 2013-03-15 2022-06-21 Corium International, Inc. Microarray for delivery of therapeutic agent and methods of use
US10384045B2 (en) 2013-03-15 2019-08-20 Corium, Inc. Microarray with polymer-free microstructures, methods of making, and methods of use
CN104095761A (zh) * 2013-04-08 2014-10-15 上海汇林医药科技有限公司 一种高分子聚合物微针贴剂及其应用
TWI528975B (zh) * 2013-07-12 2016-04-11 國立成功大學 微針經皮傳輸裝置及應用其之微針經皮傳輸方法
US10869832B2 (en) * 2013-07-12 2020-12-22 National Cheng Kung University Substance delivery device and substance delivery method using the same
US9694142B2 (en) * 2013-09-03 2017-07-04 Visage Sculpture, PLLC Device for percutaneous delivery of therapeutic agents, and a method for its use
CA2924447C (en) * 2013-09-18 2020-08-04 Cosmed Pharmaceutical Co., Ltd. Microneedle patch application device and patch holder
US20150141910A1 (en) * 2013-11-14 2015-05-21 University Medical Pharmaceuticals Corporation Microneedles for therapeutic agent delivery with improved mechanical properties
EP3148630B1 (en) * 2014-05-28 2022-12-07 Mdapp S.R.L. A flexible dissolvable patch and its method of fabricating
US10624843B2 (en) * 2014-09-04 2020-04-21 Corium, Inc. Microstructure array, methods of making, and methods of use
CN104434561A (zh) * 2014-11-10 2015-03-25 广州市博卡利生物科技有限公司 一种微针面膜
CN104644456A (zh) * 2015-01-16 2015-05-27 刘春生 透皮吸收可溶性制剂贴片、制备方法及方法中使用的工具
US10441768B2 (en) 2015-03-18 2019-10-15 University of Pittsburgh—of the Commonwealth System of Higher Education Bioactive components conjugated to substrates of microneedle arrays
KR102493996B1 (ko) * 2015-04-29 2023-01-31 주식회사 엘지생활건강 항염 효과의 성분을 포함하는 저자극 용해성 미세바늘 패치
CN104826228B (zh) * 2015-05-25 2017-12-29 成都凤磐生物科技有限公司 用于皮肤修复与保养的生物贴
WO2017004067A1 (en) 2015-06-29 2017-01-05 Corium International, Inc. Microarray for delivery of therapeutic agent, methods of use, and methods of making
WO2017018086A1 (ja) * 2015-07-29 2017-02-02 日本写真印刷株式会社 マイクロニードルシート
US11684763B2 (en) 2015-10-16 2023-06-27 University of Pittsburgh—of the Commonwealth System of Higher Education Multi-component bio-active drug delivery and controlled release to the skin by microneedle array devices
KR101811513B1 (ko) 2015-11-25 2017-12-20 주식회사 파이안에스테틱스 마이크로 스피큘과 이의 제조용 몰드 및 이의 제조방법
CN105434332A (zh) * 2015-12-02 2016-03-30 江汉大学 水溶性生物大分子微针膜的制备方法
CN105411997A (zh) * 2015-12-30 2016-03-23 李媚 一种可降解微结构体及其制备方法
WO2017120322A1 (en) 2016-01-05 2017-07-13 University Of Pittsburgh-Of The Commonwealth System Of Higher Education Skin microenvironment targeted delivery for promoting immune and other responses
CN105797266A (zh) * 2016-03-07 2016-07-27 李媚 一种微结构体及其制备方法
KR101719319B1 (ko) * 2016-04-05 2017-03-23 주식회사 엘지생활건강 효율적인 피부 천공을 위한 마이크로니들 구조
WO2017176069A2 (ko) * 2016-04-07 2017-10-12 랩앤피플주식회사 생체흡수성 금속을 이용한 마이크로 니들
KR101878414B1 (ko) * 2016-08-12 2018-07-13 연세대학교 산학협력단 마이크로니들 패치, 이의 제조방법 및 이를 이용한 알레르기 질환 진단방법
US20180092776A1 (en) 2016-09-30 2018-04-05 Sara Heikali Method and device for treating and managing diseased ocular tissue
US11241563B2 (en) * 2016-12-22 2022-02-08 Johnson & Johnson Consumer Inc. Microneedle arrays and methods for making and using
CN106808162A (zh) * 2017-02-21 2017-06-09 中山大学 一种微针阵列电极及其制备方法
KR101776659B1 (ko) * 2017-02-27 2017-09-11 주식회사 쿼드메디슨 마이크로 니들 및 이의 제조방법
CN110582320B (zh) * 2017-05-10 2022-01-21 林治远 制造微针贴剂的方法
KR102388991B1 (ko) * 2017-05-22 2022-04-22 삼성전자주식회사 바이오 센서, 바이오 센서의 제조방법 및 생체신호 측정장치
JP7345792B2 (ja) 2017-09-19 2023-09-19 エルジー ハウスホールド アンド ヘルスケア リミテッド マイクロニードルパッチを用いたヒアルロン酸フィラー
CN109646673A (zh) * 2017-10-12 2019-04-19 秀杰股份公司 肉毒杆菌毒素的微结构制剂技术
WO2019073362A1 (en) * 2017-10-12 2019-04-18 Solyplus Berlin Gmbh METHODS OF MANUFACTURING HOMOGENEOUSLY CONCENTRATED AND HOMOGENOUS MASS POLYMERS AND THEIR APPLICATIONS
WO2019088315A1 (ko) * 2017-11-01 2019-05-09 주식회사 엘지생활건강 탈모 방지제 및 발모 치료제 전달을 위한 용해성 미세바늘 패치
KR20200108308A (ko) * 2018-01-07 2020-09-17 아브라함 아미르 피부 증강을 위한 고부하 마이크로니들 및 조성물
KR102022968B1 (ko) * 2018-01-12 2019-09-19 주식회사 에스엔비아 마이크로 니들 시트 구조 및 그 제조방법
CN108742718B (zh) * 2018-03-23 2021-04-16 苏州德锐特成像技术有限公司 一种可快速溶胀的自粘附微针贴片及其制备方法
KR102088330B1 (ko) * 2018-04-11 2020-03-12 숭실대학교산학협력단 마이크로 구조물의 피부 흡수 촉진제, 마이크로 구조물의 피부 흡수 촉진제를 포함하는 피부에 바르는 인슐린, 및 마이크로 구조물의 피부 흡수 촉진제를 포함하는 피부에 바르는 인슐린을 이용한 인슐린 투여방법
KR102604754B1 (ko) * 2018-05-18 2023-11-22 포항공과대학교 산학협력단 경피 투과형 약물 전달 패치의 제조 방법
CN112423828B (zh) * 2018-05-18 2022-10-21 浦项工科大学校产学协力团 经皮药物递送贴剂及其制造方法
CA3101595A1 (en) 2018-06-29 2020-01-02 Johnson & Johnson Consumer Inc. Three-dimensional microfluidics devices for the delivery of actives
US20210244925A1 (en) * 2018-07-19 2021-08-12 Hisamitsu Pharmaceutical Co., Inc. Microneedle sheet production method and microneedle sheet
US11517729B2 (en) * 2018-08-20 2022-12-06 University Of Washington Integrated fiber microneedle device for drug and vaccine delivery
CN111331681B (zh) * 2018-08-21 2021-05-18 绍兴玖越智能装备有限公司 一种超市初加工用金针菇撕分辅助器及使用方法
KR102039582B1 (ko) * 2018-12-12 2019-11-01 주식회사 라파스 인장 공정으로 제조하기에 적합한 마이크로니들 재료의 적합성 시험 방법 및 이를 포함하는 마이크로니들 제조 방법
KR102187439B1 (ko) * 2019-01-30 2020-12-07 주식회사 라파스 마이크로니들 패취를 이용한 최소 침습적 피부 생체 검사 방법
EP3854375A1 (en) * 2020-01-23 2021-07-28 Paean Aesthetics Inc Micro-spicule composition to control its shape and method for producing the same
JP7399295B2 (ja) * 2020-04-06 2023-12-15 イルロン カンパニー リミテッド 化粧品吸収誘導用微細針が取り付けられた化粧品注入器及びその制作方法
CN112675124A (zh) * 2020-12-29 2021-04-20 浙江摩达生物科技有限公司 一种改性自溶性透明质酸微针的制备方法及其在戒毒药物领域的应用
CN113520905A (zh) * 2021-03-25 2021-10-22 甘肃天际生物科技有限公司 一种速溶胶原蛋白微针及其制备方法
WO2023197672A1 (zh) * 2022-04-15 2023-10-19 优微（珠海）生物科技有限公司 一种平面微针、微针贴及制造设备、立形设备和制备方法
KR20230165563A (ko) 2022-05-27 2023-12-05 주식회사 바이콘 아텔로콜라겐 및 히알루론산으로 이루어진 조성물 및 상기 조성물을 이용한 골격 구조체.

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004105729A2 (en) * 2002-08-08 2004-12-09 Alza Corporation Transdermal vaccine delivery device having coated microprotrusions
WO2005004729A1 (en) * 2003-06-30 2005-01-20 Alza Corporation Method for coating skin piercing microprojections
JP2005021678A (ja) * 2003-06-10 2005-01-27 Medorekkusu:Kk 経皮投薬用パッドベースの製造方法及び経皮投薬用パッドベース、並びに注射針
WO2006080508A1 (ja) * 2005-01-31 2006-08-03 Bioserentach Co., Ltd. 経皮吸収製剤、経皮吸収製剤保持シート、及び経皮吸収製剤保持用具

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4090018B2 (ja) 2002-02-18 2008-05-28 Ｆｏｒ Ｈｅａｄ株式会社 機能性マイクロパイル及びその製造方法
EP1632263A4 (en) 2003-06-10 2008-04-30 Medrx Co Ltd METHOD FOR THE PRODUCTION OF A REFERENCE BASIS FOR TRANSDERMAL MEDICINAL ADMINISTRATION, BASIC BASIS FOR TRANSDERMAL ADMINISTRATIVE ADMINISTRATION AND NEEDLE
CN2662899Y (zh) * 2003-11-20 2004-12-15 陈以国 梅花丛针贴
US20090264425A1 (en) * 2004-12-22 2009-10-22 Pfizer Limited Chemical compounds
WO2007071448A2 (en) * 2005-12-23 2007-06-28 Partnership & Corp. Technology Transfer Synthetic peptides for use as inhibitors of neurotransmitter secretion and as inducers of muscle relaxation

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004105729A2 (en) * 2002-08-08 2004-12-09 Alza Corporation Transdermal vaccine delivery device having coated microprotrusions
JP2005021678A (ja) * 2003-06-10 2005-01-27 Medorekkusu:Kk 経皮投薬用パッドベースの製造方法及び経皮投薬用パッドベース、並びに注射針
WO2005004729A1 (en) * 2003-06-30 2005-01-20 Alza Corporation Method for coating skin piercing microprojections
WO2006080508A1 (ja) * 2005-01-31 2006-08-03 Bioserentach Co., Ltd. 経皮吸収製剤、経皮吸収製剤保持シート、及び経皮吸収製剤保持用具

Cited By (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPWO2011002034A1 (ja) * 2009-07-01 2012-12-13 凸版印刷株式会社 針状体
JP2014223554A (ja) * 2009-07-01 2014-12-04 凸版印刷株式会社 針状体
JP5663477B2 (ja) * 2009-07-01 2015-02-04 凸版印刷株式会社 針状体
WO2011002034A1 (ja) * 2009-07-01 2011-01-06 凸版印刷株式会社 針状体
US10603477B2 (en) 2014-03-28 2020-03-31 Allergan, Inc. Dissolvable microneedles for skin treatment
US10987503B2 (en) 2014-03-28 2021-04-27 Allergan, Inc. Dissolvable microneedles for skin treatment
CN109069812A (zh) * 2016-04-07 2018-12-21 实验室和人们 利用生物可吸收金属的微针
CN109069812B (zh) * 2016-04-07 2021-05-07 实验室和人们 利用生物可吸收金属的微针
US11065428B2 (en) 2017-02-17 2021-07-20 Allergan, Inc. Microneedle array with active ingredient
WO2020004666A1 (en) 2018-06-29 2020-01-02 L'oreal Cosmetic process using microneedle sheet
WO2020004428A1 (en) 2018-06-29 2020-01-02 L'oreal Cosmetic process using microneedle sheet
WO2020017441A1 (en) 2018-07-17 2020-01-23 L'oreal Microneedle sheet
WO2020130157A1 (en) 2018-12-21 2020-06-25 L'oreal Kit and cosmetic process using microneedle sheet
EP3695876A1 (en) 2019-02-18 2020-08-19 L'oreal Pencil for inserting micro-implants inside upper skin layers
WO2020169443A1 (en) 2019-02-18 2020-08-27 L'oreal Pencil for inserting micro-implants inside upper skin layers
EP3698841A1 (en) 2019-02-19 2020-08-26 L'oreal Injection device
WO2020169640A1 (en) 2019-02-19 2020-08-27 L'oreal Injection device
WO2020200407A1 (en) 2019-03-29 2020-10-08 L'oreal Frozen micro-implants and method of making same

Also Published As

Publication number Publication date
KR20100025509A (ko) 2010-03-09
US20100228203A1 (en) 2010-09-09
JP2008284318A (ja) 2008-11-27
CN101687090A (zh) 2010-03-31
CN101687090B (zh) 2012-09-19
US8167852B2 (en) 2012-05-01
KR101400545B1 (ko) 2014-05-28

Similar Documents

Publication Publication Date Title
WO2008139786A1 (ja) 微細針ディバイス及びその製造方法
Gittard et al. The effects of geometry on skin penetration and failure of polymer microneedles
ATE554804T1 (de) Verfahren zur herstellung von beschichteten medizinischen vorrichtungen
WO2007021964A3 (en) Intravesical drug delivery device and method
NZ600649A (en) Anti-infective device comprising a catheter and an anti-infective composition
WO2008051265A3 (en) Engineered cell growth on polymeric films and biotechnological applications there of
WO2010087971A3 (en) Drug delivery and substance transfer facilitated by nano-enhanced device having aligned carbon nanotubes protruding from device surface
WO2010052007A3 (en) Surgical suture material with barbs cut into it in the undrawn state
WO2008060359A3 (en) Biodegradable ocular implants and methods for treating ocular conditions
EP2338551A3 (en) A device and a system for delivery of biological material
EP2067455A8 (en) Method for manufacturing of a urisheath
ATE500854T1 (de) Beschichtete medizinische vorrichtungen und verfahren zu ihrer herstellung
WO2008060877A3 (en) Medical devices and related methods
WO2006114098A3 (en) Biocompatible material for surgical implants and cell guiding tissue culture surfaces
EP2752171A3 (en) Method for retaining a vascular stent on a catheter
WO2009102792A3 (en) Human collagen products and methods for producing human collagen products
EP1834589A3 (en) Micropore forming system, micropore forming device, chip container, and chip container kit
WO2009091737A3 (en) Low viscosity liquid polymeric delivery system
EP2020455A3 (en) Fiber, fiber assembly, and fiber producing method
EP1991594A4 (en) HYBRID POLYMER OF ACRYLATE BASED ON NATURAL FATTY ACIDS AND METHOD OF MAKING SAME
PH12014502430A1 (en) Transpulmonary liposome for controlling drug arrival
EP1882483A3 (en) Medical implant bearing material
EP4289451A3 (en) Surgical needle coatings and methods
EP2545945A3 (de) Implantat, Bauteilset, Verfahren zur Herstellung eines Implantats und/oder eines Bauteilsets und Vorrichtung zur Herstellung eines Implantats und/oder eines Bauteilsets
ES2169681A1 (es) Metodo de produccion de filmes de quitosan con una alta capacidad de adherencia celular, producto obrenido y aplicaciones.

Legal Events

Date Code Title Description
WWE Wipo information: entry into national phase

Ref document number: 200880015048.2

Country of ref document: CN

121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 08739584

Country of ref document: EP

Kind code of ref document: A1

WWE Wipo information: entry into national phase

Ref document number: 12599860

Country of ref document: US

ENP Entry into the national phase

Ref document number: 20097023674

Country of ref document: KR

Kind code of ref document: A

NENP Non-entry into the national phase

Ref country code: DE

122 Ep: pct application non-entry in european phase

Ref document number: 08739584

Country of ref document: EP

Kind code of ref document: A1