WO2003045914A1 - Cristaux de sels stereoisomeres non naturels de monatine et leur utilisation - Google Patents
Cristaux de sels stereoisomeres non naturels de monatine et leur utilisation Download PDFInfo
- Publication number
- WO2003045914A1 WO2003045914A1 PCT/JP2002/012472 JP0212472W WO03045914A1 WO 2003045914 A1 WO2003045914 A1 WO 2003045914A1 JP 0212472 W JP0212472 W JP 0212472W WO 03045914 A1 WO03045914 A1 WO 03045914A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- monatin
- crystals
- salts
- sweeteners
- utilization
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D209/20—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals substituted additionally by nitrogen atoms, e.g. tryptophane
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
- A23L2/52—Adding ingredients
- A23L2/60—Sweeteners
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L27/00—Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
- A23L27/20—Synthetic spices, flavouring agents or condiments
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L27/00—Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
- A23L27/30—Artificial sweetening agents
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L27/00—Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
- A23L27/30—Artificial sweetening agents
- A23L27/31—Artificial sweetening agents containing amino acids, nucleotides, peptides or derivatives
- A23L27/32—Artificial sweetening agents containing amino acids, nucleotides, peptides or derivatives containing dipeptides or derivatives
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nutrition Science (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Seasonings (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Indole Compounds (AREA)
Priority Applications (10)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AU2002349604A AU2002349604A1 (en) | 2001-11-30 | 2002-11-29 | Crystals of non-natural stereoisomer salts of monatin and utilization thereof |
CNB028239571A CN1319943C (zh) | 2001-11-30 | 2002-11-29 | 莫那特因的非天然型立体异构体盐的结晶及其使用 |
KR1020047008237A KR100949049B1 (ko) | 2001-11-30 | 2002-11-29 | 모나틴의 비천연형 입체이성체 염의 결정 및 이의 사용 |
JP2003547366A JP4991091B2 (ja) | 2001-11-30 | 2002-11-29 | モナティンの非天然型立体異性体塩の結晶及びその使用 |
EP02783681A EP1449832A4 (en) | 2001-11-30 | 2002-11-29 | CRYSTALS OF NON-NATURAL STEREO-ISOMERAL SALTS OF MONATIN AND THEIR USE |
CA2467285A CA2467285C (en) | 2001-11-30 | 2002-11-29 | Crystals of non-natural-type stereoisomer salt of monatin and use thereof |
US10/856,756 US7795296B2 (en) | 2001-11-30 | 2004-06-01 | Crystals of non-natural-type stereoisomer salt of monatin and use thereof |
US12/825,886 US7951835B2 (en) | 2001-11-30 | 2010-06-29 | Crystals of non-natural-type stereoisomer salt of monatin and use thereof |
US13/081,024 US20110189368A1 (en) | 2001-11-30 | 2011-04-06 | Crystals of non-natural-type stereoisomer salt of monatin and use thereof |
US13/558,870 US20120295004A1 (en) | 2001-11-30 | 2012-07-26 | Crystals of non-natural-type stereoisomer salt of monatin and use thereof |
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2001366053 | 2001-11-30 | ||
JP2001-366053 | 2001-11-30 | ||
JP2002-182032 | 2002-06-21 | ||
JP2002182032 | 2002-06-21 |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US10/856,756 Continuation US7795296B2 (en) | 2001-11-30 | 2004-06-01 | Crystals of non-natural-type stereoisomer salt of monatin and use thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
WO2003045914A1 true WO2003045914A1 (fr) | 2003-06-05 |
Family
ID=26624781
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/JP2002/012472 WO2003045914A1 (fr) | 2001-11-30 | 2002-11-29 | Cristaux de sels stereoisomeres non naturels de monatine et leur utilisation |
Country Status (9)
Country | Link |
---|---|
US (4) | US7795296B2 (ja) |
EP (2) | EP2409968A1 (ja) |
JP (2) | JP4991091B2 (ja) |
KR (2) | KR100966035B1 (ja) |
CN (1) | CN1319943C (ja) |
AU (1) | AU2002349604A1 (ja) |
CA (1) | CA2467285C (ja) |
RU (1) | RU2303030C2 (ja) |
WO (1) | WO2003045914A1 (ja) |
Cited By (28)
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---|---|---|---|---|
EP1533300A1 (en) * | 2003-11-21 | 2005-05-25 | Ajinomoto Co., Inc. | Organic amine salts of glutamic acid derivatives and their application |
JP2005139108A (ja) * | 2003-11-05 | 2005-06-02 | Ajinomoto Co Inc | 新規アミノ酸誘導体及び甘味剤 |
EP1616860A1 (en) | 2004-07-14 | 2006-01-18 | Ajinomoto Co., Inc. | Crystalline form of (2R,4R)-Monatin potassium salt and sweetener composition containing same |
WO2006011613A1 (ja) * | 2004-07-27 | 2006-02-02 | Ajinomoto Co., Inc. | モナティンまたはその塩の製造方法 |
JP2006052213A (ja) * | 2004-07-14 | 2006-02-23 | Ajinomoto Co Inc | (2r,4r)−モナティンのカリウム塩結晶 |
WO2006041216A1 (ja) * | 2004-10-15 | 2006-04-20 | Ajinomoto Co., Inc. | 甘味料組成物 |
JPWO2005001105A1 (ja) * | 2003-06-26 | 2006-08-10 | 味の素株式会社 | モナティンの製造方法 |
JP2007501004A (ja) * | 2003-08-01 | 2007-01-25 | カーギル,インコーポレイティド | モナチン卓上甘味料組成物およびその製造方法 |
JP2007502117A (ja) * | 2003-08-14 | 2007-02-08 | カーギル,インコーポレイティド | モナチンを含有するチューインガムとその製造法 |
JP2007503214A (ja) * | 2003-08-25 | 2007-02-22 | カーギル,インコーポレイティド | モナチンを含む飲料組成物及びその製造方法 |
US7572607B2 (en) | 2002-04-23 | 2009-08-11 | Cargill, Incorporated | Polypeptides and biosynthetic pathways for the production of monatin and its precursors |
US7582455B2 (en) | 2005-04-26 | 2009-09-01 | Cargill, Incorporated | Polypeptides and biosynthetic pathways for the production of stereoisomers of monatin and their precursors |
EP2107053A1 (en) | 2008-03-11 | 2009-10-07 | Ajinomoto Co., Inc. | Hydrate crystals of (2R,4R)-Monatin monosodium salt |
JP2010241815A (ja) * | 2010-06-01 | 2010-10-28 | Ajinomoto Co Inc | グルタミン酸誘導体の有機アミン塩及びその利用 |
US7888081B2 (en) | 2006-05-24 | 2011-02-15 | Cargill, Incorporated | Methods and systems for increasing production of equilibrium reactions |
US7935377B2 (en) * | 2004-06-04 | 2011-05-03 | Ajinomoto Co., Inc. | Crystals of free (2R, 4R)-monatin and use thereof |
US8003361B2 (en) | 2007-10-01 | 2011-08-23 | Cargill Incorporated | Production of monatin enantiomers |
US8076107B2 (en) | 2007-10-01 | 2011-12-13 | Cargill, Incorporated | Production of monatin stereoisomers |
US8076108B2 (en) | 2005-04-26 | 2011-12-13 | Cargill, Incorporated | Polypeptides and biosynthetic pathways for the production of stereoisomers of monatin and their precursors |
US8153405B2 (en) | 2005-04-20 | 2012-04-10 | Cargill, Incorporated | Products and methods for in vivo secretion of monatin |
US8158389B2 (en) | 2005-04-20 | 2012-04-17 | Cargill, Incorporated | Products and methods for in vivo secretion of monatin |
JP2012082223A (ja) * | 2004-02-27 | 2012-04-26 | Ajinomoto Co Inc | モナティンの製造方法 |
US8206955B2 (en) | 2003-10-21 | 2012-06-26 | Cargill, Incorporated | Production of monatin and monatin precursors |
JP2012520079A (ja) * | 2009-03-12 | 2012-09-06 | カーギル・インコーポレイテッド | モナチンおよびカルシウムを含む組成物 |
WO2012169661A1 (ja) * | 2011-06-08 | 2012-12-13 | 味の素株式会社 | モナティン多価金属塩結晶 |
US8367847B2 (en) | 2007-10-01 | 2013-02-05 | Cargill, Incorporated | Production of monatin enantiomers |
US8372989B2 (en) | 2002-04-23 | 2013-02-12 | Cargill, Incorporated | Polypeptides and biosynthetic pathways for the production of monatin and its precursors |
WO2013073679A1 (ja) * | 2011-11-17 | 2013-05-23 | 味の素株式会社 | (2r,4r)モナティン多価金属塩結晶の製造方法 |
Families Citing this family (36)
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---|---|---|---|---|
WO2003045914A1 (fr) * | 2001-11-30 | 2003-06-05 | Ajinomoto Co., Inc. | Cristaux de sels stereoisomeres non naturels de monatine et leur utilisation |
US7297800B2 (en) * | 2001-12-27 | 2007-11-20 | Ajinomoto Co., Inc. | Process of producing glutamate derivatives |
AU2002349606A1 (en) | 2001-12-27 | 2003-07-30 | Ajinomoto Co., Inc. | Processes for the preparation of glutamic acid compounds and intermediates thereof and novel intermediates used in the processes |
WO2004018672A1 (ja) | 2002-08-26 | 2004-03-04 | Ajinomoto Co., Inc. | 新規アルドラーゼおよび置換α−ケト酸の製造方法 |
AU2003289264A1 (en) * | 2002-12-09 | 2004-06-30 | Ajinomoto Co., Inc. | Mutant d-aminotransferase and process for producing optically active glutamic acid derivative using the same |
CA2506247C (en) * | 2004-06-07 | 2012-02-21 | Ajinomoto Co., Inc. | Novel aldolase, and method for producing optically active ihog and monatin |
US7180370B2 (en) * | 2004-09-01 | 2007-02-20 | Micron Technology, Inc. | CMOS amplifiers with frequency compensating capacitors |
CN101035903A (zh) * | 2004-10-05 | 2007-09-12 | 味之素株式会社 | 用于从肟基酸生产氨基酸衍生物的方法 |
US8956677B2 (en) * | 2005-11-23 | 2015-02-17 | The Coca-Cola Company | High-potency sweetener composition with glucosamine and compositions sweetened therewith |
US8993027B2 (en) * | 2005-11-23 | 2015-03-31 | The Coca-Cola Company | Natural high-potency tabletop sweetener compositions with improved temporal and/or flavor profile, methods for their formulation, and uses |
US20070116831A1 (en) * | 2005-11-23 | 2007-05-24 | The Coca-Cola Company | Dental Composition with High-Potency Sweetener |
US20070116800A1 (en) * | 2005-11-23 | 2007-05-24 | The Coca-Cola Company | Chewing Gum with High-Potency Sweetener |
US9144251B2 (en) * | 2005-11-23 | 2015-09-29 | The Coca-Cola Company | High-potency sweetener composition with mineral and compositions sweetened therewith |
KR20080071606A (ko) * | 2005-11-23 | 2008-08-04 | 더 코카콜라 컴파니 | 시간 특성 및/또는 향미 특성이 개선된 인공 감미료조성물과 이들의 제제 방법 및 용도 |
US20070116822A1 (en) * | 2005-11-23 | 2007-05-24 | The Coca-Cola Company | High-potency sweetener composition with saponin and compositions sweetened therewith |
US20070134391A1 (en) * | 2005-11-23 | 2007-06-14 | The Coca-Cola Company | High-Potency Sweetener Composition for Treatment and/or Prevention of Autoimmune Disorders and Compositions Sweetened Therewith |
US8377491B2 (en) * | 2005-11-23 | 2013-02-19 | The Coca-Cola Company | High-potency sweetener composition with vitamin and compositions sweetened therewith |
US8435587B2 (en) * | 2005-11-23 | 2013-05-07 | The Coca-Cola Company | High-potency sweetener composition with long-chain primary aliphatic saturated alcohol and compositions sweetened therewith |
US20070116836A1 (en) * | 2005-11-23 | 2007-05-24 | The Coca-Cola Company | High-Potency Sweetener Composition for Treatment and/or Prevention of Osteoporosis and Compositions Sweetened Therewith |
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US8524303B2 (en) * | 2005-11-23 | 2013-09-03 | The Coca-Cola Company | High-potency sweetener composition with phytosterol and compositions sweetened therewith |
US20070116833A1 (en) * | 2005-11-23 | 2007-05-24 | The Coca-Cola Company | High-Potency Sweetener Composition with Calcium and Compositions Sweetened Therewith |
US20070116839A1 (en) * | 2005-11-23 | 2007-05-24 | The Coca-Cola Company | High-Potency Sweetener Composition With C-Reactive Protein Reducing Substance and Compositions Sweetened Therewith |
US20070116825A1 (en) * | 2005-11-23 | 2007-05-24 | The Coca-Cola Company | Confection with High-Potency Sweetener |
US8956678B2 (en) * | 2005-11-23 | 2015-02-17 | The Coca-Cola Company | High-potency sweetener composition with preservative and compositions sweetened therewith |
US20070116829A1 (en) * | 2005-11-23 | 2007-05-24 | The Coca-Cola Company | Pharmaceutical Composition with High-Potency Sweetener |
US9101160B2 (en) | 2005-11-23 | 2015-08-11 | The Coca-Cola Company | Condiments with high-potency sweetener |
BRPI0708673A2 (pt) | 2006-03-07 | 2011-06-07 | Cargill Inc | método para fabricação de polipeptìdeos com atividade de aldolase e polinucleotìdeos que codificam estes polipeptìdeos |
US20090198072A1 (en) * | 2006-05-24 | 2009-08-06 | Cargill, Incorporated | Methods and systems for increasing production of equilibrium reactions |
US9101161B2 (en) * | 2006-11-02 | 2015-08-11 | The Coca-Cola Company | High-potency sweetener composition with phytoestrogen and compositions sweetened therewith |
US8017168B2 (en) | 2006-11-02 | 2011-09-13 | The Coca-Cola Company | High-potency sweetener composition with rubisco protein, rubiscolin, rubiscolin derivatives, ace inhibitory peptides, and combinations thereof, and compositions sweetened therewith |
US20080107787A1 (en) * | 2006-11-02 | 2008-05-08 | The Coca-Cola Company | Anti-Diabetic Composition with High-Potency Sweetener |
CN101239941B (zh) | 2007-02-08 | 2012-02-29 | 味之素株式会社 | 光学活性化合物的制造方法 |
US9877500B2 (en) | 2007-03-14 | 2018-01-30 | Concentrate Manufacturing Company Of Ireland | Natural beverage products |
US8771997B2 (en) | 2011-04-20 | 2014-07-08 | Ajinomoto Co., Inc. | Method for producing monatin using an L-amino acid aminotransferase |
US20130011538A1 (en) * | 2011-06-08 | 2013-01-10 | Ajinomoto Co., Inc. | Crystal of multivalent metal salt of monatin |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB2205834A (en) * | 1987-06-15 | 1988-12-21 | South African Inventions | 3-(1-amino-1,3-dicarboxy-3-hydroxy-but-4-yl)-indole compounds |
EP0438314A1 (en) * | 1990-01-19 | 1991-07-24 | Technology Finance Corporation (Proprietary) Limited | Process for the production of 3-(1-amino-1,3-dicarboxy-3-hydroxy-but-4-yl) indole |
US5994559A (en) * | 1998-08-06 | 1999-11-30 | The Board Of Governors For Higher Education, State Of Rhode Island And Providence Plantations | Synthesis of monatin-A high intensity natural sweetener |
JP2002060382A (ja) * | 2000-08-22 | 2002-02-26 | Ajinomoto Co Inc | モナティンの立体異性体及びその使用、並びにモナティン類の製造方法及びそのための中間体 |
Family Cites Families (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ZA884220B (en) | 1987-06-15 | 1989-02-22 | South African Inventions | 3-(1-amino-1,3-dicarboxy-3-hydroxy-but-4-yl)-indole compound |
WO2003045914A1 (fr) * | 2001-11-30 | 2003-06-05 | Ajinomoto Co., Inc. | Cristaux de sels stereoisomeres non naturels de monatine et leur utilisation |
AU2002349606A1 (en) * | 2001-12-27 | 2003-07-30 | Ajinomoto Co., Inc. | Processes for the preparation of glutamic acid compounds and intermediates thereof and novel intermediates used in the processes |
US7297800B2 (en) * | 2001-12-27 | 2007-11-20 | Ajinomoto Co., Inc. | Process of producing glutamate derivatives |
JP2003292484A (ja) * | 2002-04-01 | 2003-10-15 | Ajinomoto Co Inc | γ−ヒドロキシアミノ酸誘導体及びモナティン類の製造方法 |
WO2004018672A1 (ja) * | 2002-08-26 | 2004-03-04 | Ajinomoto Co., Inc. | 新規アルドラーゼおよび置換α−ケト酸の製造方法 |
AU2003289264A1 (en) * | 2002-12-09 | 2004-06-30 | Ajinomoto Co., Inc. | Mutant d-aminotransferase and process for producing optically active glutamic acid derivative using the same |
JP4217954B2 (ja) | 2003-02-12 | 2009-02-04 | 富士ゼロックス株式会社 | 画像探索装置 |
WO2005001105A1 (ja) * | 2003-06-26 | 2005-01-06 | Ajinomoto Co., Inc. | モナティンの製造方法 |
JP4500977B2 (ja) * | 2003-11-05 | 2010-07-14 | 味の素株式会社 | 新規アミノ酸誘導体及び甘味剤 |
JP5113978B2 (ja) * | 2003-11-21 | 2013-01-09 | 味の素株式会社 | グルタミン酸誘導体の有機アミン塩及びその利用 |
JP5319885B2 (ja) * | 2004-02-27 | 2013-10-16 | 味の素株式会社 | モナティンの製造方法 |
JP4604524B2 (ja) * | 2004-03-16 | 2011-01-05 | 味の素株式会社 | 変異型アルドラーゼ、並びにこれを用いた光学活性ihog及び光学活性モナティンの製造方法 |
US7935377B2 (en) * | 2004-06-04 | 2011-05-03 | Ajinomoto Co., Inc. | Crystals of free (2R, 4R)-monatin and use thereof |
CA2506247C (en) * | 2004-06-07 | 2012-02-21 | Ajinomoto Co., Inc. | Novel aldolase, and method for producing optically active ihog and monatin |
KR101216575B1 (ko) * | 2004-07-14 | 2012-12-31 | 아지노모토 가부시키가이샤 | (2r,4r)-모나틴 칼륨 염 결정 및 이를 함유하는 감미료조성물 |
JP2007284349A (ja) * | 2004-07-27 | 2007-11-01 | Ajinomoto Co Inc | モナティンまたはその塩の製造方法 |
CN101035903A (zh) * | 2004-10-05 | 2007-09-12 | 味之素株式会社 | 用于从肟基酸生产氨基酸衍生物的方法 |
CN101035442B (zh) * | 2004-10-15 | 2012-04-11 | 味之素株式会社 | 甜味剂组合物 |
CN101239941B (zh) * | 2007-02-08 | 2012-02-29 | 味之素株式会社 | 光学活性化合物的制造方法 |
EP2107053A1 (en) * | 2008-03-11 | 2009-10-07 | Ajinomoto Co., Inc. | Hydrate crystals of (2R,4R)-Monatin monosodium salt |
-
2002
- 2002-11-29 WO PCT/JP2002/012472 patent/WO2003045914A1/ja active Application Filing
- 2002-11-29 KR KR1020097025094A patent/KR100966035B1/ko not_active IP Right Cessation
- 2002-11-29 CA CA2467285A patent/CA2467285C/en not_active Expired - Fee Related
- 2002-11-29 RU RU2004119843/04A patent/RU2303030C2/ru not_active IP Right Cessation
- 2002-11-29 KR KR1020047008237A patent/KR100949049B1/ko not_active IP Right Cessation
- 2002-11-29 EP EP11180523A patent/EP2409968A1/en not_active Withdrawn
- 2002-11-29 JP JP2003547366A patent/JP4991091B2/ja not_active Expired - Fee Related
- 2002-11-29 AU AU2002349604A patent/AU2002349604A1/en not_active Abandoned
- 2002-11-29 CN CNB028239571A patent/CN1319943C/zh not_active Expired - Fee Related
- 2002-11-29 EP EP02783681A patent/EP1449832A4/en not_active Withdrawn
-
2004
- 2004-06-01 US US10/856,756 patent/US7795296B2/en not_active Expired - Fee Related
-
2009
- 2009-09-16 JP JP2009214343A patent/JP2009298807A/ja active Pending
-
2010
- 2010-06-29 US US12/825,886 patent/US7951835B2/en not_active Expired - Fee Related
-
2011
- 2011-04-06 US US13/081,024 patent/US20110189368A1/en not_active Abandoned
-
2012
- 2012-07-26 US US13/558,870 patent/US20120295004A1/en not_active Abandoned
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
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GB2205834A (en) * | 1987-06-15 | 1988-12-21 | South African Inventions | 3-(1-amino-1,3-dicarboxy-3-hydroxy-but-4-yl)-indole compounds |
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Also Published As
Publication number | Publication date |
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JP4991091B2 (ja) | 2012-08-01 |
US7951835B2 (en) | 2011-05-31 |
RU2004119843A (ru) | 2005-04-10 |
KR20040068173A (ko) | 2004-07-30 |
KR100949049B1 (ko) | 2010-03-25 |
US20110189368A1 (en) | 2011-08-04 |
CA2467285C (en) | 2011-08-16 |
US20120295004A1 (en) | 2012-11-22 |
RU2303030C2 (ru) | 2007-07-20 |
JP2009298807A (ja) | 2009-12-24 |
EP2409968A1 (en) | 2012-01-25 |
AU2002349604A1 (en) | 2003-06-10 |
CA2467285A1 (en) | 2003-06-05 |
CN1319943C (zh) | 2007-06-06 |
US20100330245A1 (en) | 2010-12-30 |
EP1449832A4 (en) | 2005-02-02 |
KR20100003311A (ko) | 2010-01-07 |
EP1449832A1 (en) | 2004-08-25 |
JPWO2003045914A1 (ja) | 2005-04-07 |
US7795296B2 (en) | 2010-09-14 |
US20050020508A1 (en) | 2005-01-27 |
KR100966035B1 (ko) | 2010-06-25 |
CN1599719A (zh) | 2005-03-23 |
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