WO1997005185B1 - Hydrogels multiblocs biodegradables destines a etre utilises comme agents de liberation regulee pour l'administration de medicaments et le traitement de tissus - Google Patents

Hydrogels multiblocs biodegradables destines a etre utilises comme agents de liberation regulee pour l'administration de medicaments et le traitement de tissus

Info

Publication number
WO1997005185B1
WO1997005185B1 PCT/US1996/012285 US9612285W WO9705185B1 WO 1997005185 B1 WO1997005185 B1 WO 1997005185B1 US 9612285 W US9612285 W US 9612285W WO 9705185 B1 WO9705185 B1 WO 9705185B1
Authority
WO
WIPO (PCT)
Prior art keywords
macromer
composition
hydrophobic
group
gel
Prior art date
Application number
PCT/US1996/012285
Other languages
English (en)
Other versions
WO1997005185A2 (fr
WO1997005185A3 (fr
Filing date
Publication date
Application filed filed Critical
Priority to JP9507762A priority Critical patent/JPH11510837A/ja
Priority to EP96926138A priority patent/EP0842209B1/fr
Priority to DE69636626T priority patent/DE69636626T2/de
Publication of WO1997005185A2 publication Critical patent/WO1997005185A2/fr
Publication of WO1997005185A3 publication Critical patent/WO1997005185A3/fr
Publication of WO1997005185B1 publication Critical patent/WO1997005185B1/fr
Priority to MXPA/A/1998/001706A priority patent/MXPA98001706A/xx

Links

Abstract

Macromères gélifiants comprenant au moins quatre blocs polymères, deux d'entre eux au moins étant hydrophobes et l'un d'entre eux au moins étant hydrophile, et comportant un groupe pouvant subir une réticulation. Ces macromères peuvent subir une réticulation covalente permettant de former un gel sur un tissu in vivo. Les gels obtenus à partir des macromères possèdent plusieurs propriétés: ils sont notamment thermosensibles et lipophiles. Ils peuvent être utilisés dans diverses applications médicales, dont l'administration de médicaments et le revêtement de tissus.
PCT/US1996/012285 1995-07-28 1996-07-26 Hydrogels multiblocs biodegradables destines a etre utilises comme agents de liberation regulee pour l'administration de medicaments et le traitement de tissus WO1997005185A2 (fr)

Priority Applications (4)

Application Number Priority Date Filing Date Title
JP9507762A JPH11510837A (ja) 1995-07-28 1996-07-26 薬物送達のための制御された放出薬剤および組織処置薬剤としての使用のためのマルチブロック生分解性ヒドロゲル
EP96926138A EP0842209B1 (fr) 1995-07-28 1996-07-26 Hydrogels multiblocs biodegradables destines a etre utilises comme agents de liberation regulee pour l'administration de medicaments et le traitement de tissus
DE69636626T DE69636626T2 (de) 1995-07-28 1996-07-26 Biologische abbaubare multiblokhydrogene und ihre verwendung wie trägerstoffe fur kontrollierte freisetzung pharmakologisch activen werstoffe und gewebekontaktmaterialen
MXPA/A/1998/001706A MXPA98001706A (en) 1995-09-08 1998-03-03 Articles coated with dependable coatings capable of accepting organic pigment electrofotograf

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US172395P 1995-07-28 1995-07-28
US60/001,723 1995-07-28

Publications (3)

Publication Number Publication Date
WO1997005185A2 WO1997005185A2 (fr) 1997-02-13
WO1997005185A3 WO1997005185A3 (fr) 1997-03-13
WO1997005185B1 true WO1997005185B1 (fr) 1997-05-15

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1996/012285 WO1997005185A2 (fr) 1995-07-28 1996-07-26 Hydrogels multiblocs biodegradables destines a etre utilises comme agents de liberation regulee pour l'administration de medicaments et le traitement de tissus

Country Status (7)

Country Link
US (5) US6201065B1 (fr)
EP (1) EP0842209B1 (fr)
JP (2) JPH11510837A (fr)
AT (1) ATE342295T1 (fr)
CA (1) CA2228118A1 (fr)
DE (1) DE69636626T2 (fr)
WO (1) WO1997005185A2 (fr)

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