WO1993018210A1 - Procede de preparation de derives du taxane - Google Patents
Procede de preparation de derives du taxane Download PDFInfo
- Publication number
- WO1993018210A1 WO1993018210A1 PCT/FR1993/000243 FR9300243W WO9318210A1 WO 1993018210 A1 WO1993018210 A1 WO 1993018210A1 FR 9300243 W FR9300243 W FR 9300243W WO 9318210 A1 WO9318210 A1 WO 9318210A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- radical
- general formula
- carried out
- electrolysis
- chosen
- Prior art date
Links
- 0 C[C@](C[C@]1OC[C@@]1(*)[C@]([C@](C)C([C@@](C(C1(C)C)=C(C)[C@](C2)OC([C@@](C(N)N)O)=O)O*)=O)[C@@](*)[C@@]12O)O* Chemical compound C[C@](C[C@]1OC[C@@]1(*)[C@]([C@](C)C([C@@](C(C1(C)C)=C(C)[C@](C2)OC([C@@](C(N)N)O)=O)O*)=O)[C@@](*)[C@@]12O)O* 0.000 description 2
Classifications
-
- C—CHEMISTRY; METALLURGY
- C25—ELECTROLYTIC OR ELECTROPHORETIC PROCESSES; APPARATUS THEREFOR
- C25B—ELECTROLYTIC OR ELECTROPHORETIC PROCESSES FOR THE PRODUCTION OF COMPOUNDS OR NON-METALS; APPARATUS THEREFOR
- C25B3/00—Electrolytic production of organic compounds
- C25B3/20—Processes
- C25B3/25—Reduction
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
- C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
-
- C—CHEMISTRY; METALLURGY
- C25—ELECTROLYTIC OR ELECTROPHORETIC PROCESSES; APPARATUS THEREFOR
- C25B—ELECTROLYTIC OR ELECTROPHORETIC PROCESSES FOR THE PRODUCTION OF COMPOUNDS OR NON-METALS; APPARATUS THEREFOR
- C25B11/00—Electrodes; Manufacture thereof not otherwise provided for
- C25B11/04—Electrodes; Manufacture thereof not otherwise provided for characterised by the material
- C25B11/042—Electrodes formed of a single material
- C25B11/043—Carbon, e.g. diamond or graphene
-
- C—CHEMISTRY; METALLURGY
- C25—ELECTROLYTIC OR ELECTROPHORETIC PROCESSES; APPARATUS THEREFOR
- C25B—ELECTROLYTIC OR ELECTROPHORETIC PROCESSES FOR THE PRODUCTION OF COMPOUNDS OR NON-METALS; APPARATUS THEREFOR
- C25B11/00—Electrodes; Manufacture thereof not otherwise provided for
- C25B11/04—Electrodes; Manufacture thereof not otherwise provided for characterised by the material
- C25B11/042—Electrodes formed of a single material
- C25B11/046—Alloys
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Electrochemistry (AREA)
- Materials Engineering (AREA)
- Metallurgy (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Electrolytic Production Of Non-Metals, Compounds, Apparatuses Therefor (AREA)
- Epoxy Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Abstract
Description
Claims
Priority Applications (9)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE69300766T DE69300766T2 (de) | 1992-03-13 | 1993-03-11 | Verfahren zur herstellung von taxanderivaten. |
JP5515408A JPH07504461A (ja) | 1992-03-13 | 1993-03-11 | タキサン誘導体の製造法 |
AU37563/93A AU3756393A (en) | 1992-03-13 | 1993-03-11 | Process for the preparation of taxane derivatives |
KR1019940703185A KR950700439A (ko) | 1992-03-13 | 1993-03-11 | 탁산 유도체의 제조방법(Process for the preparation of taxane derivatives) |
SK1084-94A SK108494A3 (en) | 1992-03-13 | 1993-03-11 | Process for the preparation of taxane derivatives |
EP93918756A EP0630428B1 (fr) | 1992-03-13 | 1993-03-11 | Procede de preparation de derives du taxane |
FI944190A FI944190A (fi) | 1992-03-13 | 1994-09-12 | Menetelmä taksaanijohdannaisten valmistamiseksi |
NO943371A NO943371L (no) | 1992-03-13 | 1994-09-12 | Fremgangsmåte for fremstilling av taxanderivater |
GR950401848T GR3018036T3 (en) | 1992-03-13 | 1995-11-09 | Process for the preparation of taxane derivatives. |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR92/03000 | 1992-03-13 | ||
FR9203000A FR2688518B1 (fr) | 1992-03-13 | 1992-03-13 | Procede de preparation de derives du taxane. |
Publications (1)
Publication Number | Publication Date |
---|---|
WO1993018210A1 true WO1993018210A1 (fr) | 1993-09-16 |
Family
ID=9427641
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/FR1993/000243 WO1993018210A1 (fr) | 1992-03-13 | 1993-03-11 | Procede de preparation de derives du taxane |
Country Status (21)
Country | Link |
---|---|
EP (1) | EP0630428B1 (fr) |
JP (1) | JPH07504461A (fr) |
KR (1) | KR950700439A (fr) |
AT (1) | ATE130053T1 (fr) |
AU (1) | AU3756393A (fr) |
CA (1) | CA2117552A1 (fr) |
CZ (1) | CZ218694A3 (fr) |
DE (1) | DE69300766T2 (fr) |
DK (1) | DK0630428T3 (fr) |
ES (1) | ES2079982T3 (fr) |
FI (1) | FI944190A (fr) |
FR (1) | FR2688518B1 (fr) |
GR (1) | GR3018036T3 (fr) |
HU (1) | HUT68282A (fr) |
MX (1) | MX9301345A (fr) |
NO (1) | NO943371L (fr) |
RU (1) | RU94041682A (fr) |
SK (1) | SK108494A3 (fr) |
TW (1) | TW235961B (fr) |
WO (1) | WO1993018210A1 (fr) |
ZA (1) | ZA931800B (fr) |
Cited By (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1997007110A1 (fr) * | 1995-08-11 | 1997-02-27 | Sepracor, Inc. | Procede pour preparer des derives du taxol et intermediaires pour cette preparation |
US6103698A (en) * | 1997-03-13 | 2000-08-15 | Basf Aktiengesellschaft | Dolastatin-15 derivatives in combination with taxanes |
US7589190B2 (en) | 2004-11-09 | 2009-09-15 | Enzon Pharmaceuticals, Inc. | Potent LNA oligonucleotides for the inhibition of HIF-1A expression |
US7622453B2 (en) | 2003-12-23 | 2009-11-24 | Santaris Pharma A/S | Oligomeric compounds for the modulation of Bcl-2 |
US7713738B2 (en) | 2003-02-10 | 2010-05-11 | Enzon Pharmaceuticals, Inc. | Oligomeric compounds for the modulation of survivin expression |
US7737264B2 (en) | 2002-04-05 | 2010-06-15 | Enzon Pharmaceuticals, Inc. | Oligomeric compounds for the modulation HIF-1α expression |
US8173428B2 (en) | 2004-11-09 | 2012-05-08 | Santaris Pharma A/S | LNA oligonucleotides and the treatment of cancer |
US9447138B2 (en) | 2004-11-09 | 2016-09-20 | Roche Innovation Center Copenhagen A/S | Potent LNA oligonucleotides for the inhibition of HIF-1a expression |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6794523B2 (en) | 1991-09-23 | 2004-09-21 | Florida State University | Taxanes having t-butoxycarbonyl substituted side-chains and pharmaceutical compositions containing them |
DE69434373T2 (de) * | 1993-03-22 | 2006-03-09 | Florida State University, Tallahassee | Beta-laktame zur Herstellung von Taxanen mit Furyl oder Thienyl substituierter Seitenkette |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0336840A1 (fr) * | 1988-04-06 | 1989-10-11 | Centre National De La Recherche Scientifique (Cnrs) | Procédé de préparation du taxol |
EP0253738B1 (fr) * | 1986-07-17 | 1990-01-31 | Rhone-Poulenc Sante | Dérivés du taxol, leur préparation et les compositions pharmaceutiques qui les contiennent |
WO1992001691A1 (fr) * | 1990-07-19 | 1992-02-06 | Rhone-Poulenc Rorer S.A. | Nouveaux derives de streptogramines et leur preparation |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS60187689A (ja) * | 1984-03-06 | 1985-09-25 | Otsuka Chem Co Ltd | 3−エキソメチレンセフアム誘導体の製造法 |
-
1992
- 1992-03-13 FR FR9203000A patent/FR2688518B1/fr not_active Expired - Fee Related
-
1993
- 1993-03-11 DK DK93918756.3T patent/DK0630428T3/da active
- 1993-03-11 CZ CZ942186A patent/CZ218694A3/cs unknown
- 1993-03-11 EP EP93918756A patent/EP0630428B1/fr not_active Expired - Lifetime
- 1993-03-11 SK SK1084-94A patent/SK108494A3/sk unknown
- 1993-03-11 JP JP5515408A patent/JPH07504461A/ja active Pending
- 1993-03-11 DE DE69300766T patent/DE69300766T2/de not_active Expired - Fee Related
- 1993-03-11 WO PCT/FR1993/000243 patent/WO1993018210A1/fr not_active Application Discontinuation
- 1993-03-11 CA CA002117552A patent/CA2117552A1/fr not_active Abandoned
- 1993-03-11 KR KR1019940703185A patent/KR950700439A/ko not_active Application Discontinuation
- 1993-03-11 AT AT93918756T patent/ATE130053T1/de not_active IP Right Cessation
- 1993-03-11 ES ES93918756T patent/ES2079982T3/es not_active Expired - Lifetime
- 1993-03-11 AU AU37563/93A patent/AU3756393A/en not_active Abandoned
- 1993-03-11 MX MX9301345A patent/MX9301345A/es unknown
- 1993-03-11 HU HU9402614A patent/HUT68282A/hu unknown
- 1993-03-12 ZA ZA931800A patent/ZA931800B/xx unknown
- 1993-03-13 TW TW082101872A patent/TW235961B/zh active
-
1994
- 1994-09-12 RU RU94041682/04A patent/RU94041682A/ru unknown
- 1994-09-12 NO NO943371A patent/NO943371L/no unknown
- 1994-09-12 FI FI944190A patent/FI944190A/fi not_active Application Discontinuation
-
1995
- 1995-11-09 GR GR950401848T patent/GR3018036T3/el unknown
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0253738B1 (fr) * | 1986-07-17 | 1990-01-31 | Rhone-Poulenc Sante | Dérivés du taxol, leur préparation et les compositions pharmaceutiques qui les contiennent |
EP0336840A1 (fr) * | 1988-04-06 | 1989-10-11 | Centre National De La Recherche Scientifique (Cnrs) | Procédé de préparation du taxol |
WO1992001691A1 (fr) * | 1990-07-19 | 1992-02-06 | Rhone-Poulenc Rorer S.A. | Nouveaux derives de streptogramines et leur preparation |
Non-Patent Citations (1)
Title |
---|
PATENT ABSTRACTS OF JAPAN vol. 10, no. 36 (C-328)(2093) 13 Février 1986 * |
Cited By (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1997007110A1 (fr) * | 1995-08-11 | 1997-02-27 | Sepracor, Inc. | Procede pour preparer des derives du taxol et intermediaires pour cette preparation |
US6103698A (en) * | 1997-03-13 | 2000-08-15 | Basf Aktiengesellschaft | Dolastatin-15 derivatives in combination with taxanes |
US6632795B1 (en) | 1997-03-13 | 2003-10-14 | Basf Aktiengesellschaft | Dolastatin-15 derivatives in combination with taxanes |
US8207140B2 (en) | 2002-04-05 | 2012-06-26 | Santaris Pharma A/S | Oligomeric compounds for the modulation of HIF-1α expression |
US7846911B2 (en) | 2002-04-05 | 2010-12-07 | Enzon Pharmaceuticals, Inc. | Oligomeric compounds for the modulation of HIF-1alpha expression |
US8785617B2 (en) | 2002-04-05 | 2014-07-22 | Santaris Pharma A/S | Oligomeric compounds for the modulation of HIF-1A expression |
US7737264B2 (en) | 2002-04-05 | 2010-06-15 | Enzon Pharmaceuticals, Inc. | Oligomeric compounds for the modulation HIF-1α expression |
US8357670B2 (en) | 2002-04-05 | 2013-01-22 | Enzon Pharmaceuticals, Inc. | Oligomeric compounds for the modulation of HIF-1A expression |
US7741309B2 (en) | 2003-02-10 | 2010-06-22 | Enzon Pharmaceuticals | Oligomeric compounds for the modulation of survivin expression |
US8026355B2 (en) | 2003-02-10 | 2011-09-27 | Santaris Pharma A/S | Oligomeric compounds for the modulation of survivin expression |
US7713738B2 (en) | 2003-02-10 | 2010-05-11 | Enzon Pharmaceuticals, Inc. | Oligomeric compounds for the modulation of survivin expression |
US7622453B2 (en) | 2003-12-23 | 2009-11-24 | Santaris Pharma A/S | Oligomeric compounds for the modulation of Bcl-2 |
US7939507B2 (en) | 2004-11-09 | 2011-05-10 | Enzon Pharmaceuticals, Inc. | Potent LNA oligonucleotides for the inhibition of HIF-1a expression |
US8173428B2 (en) | 2004-11-09 | 2012-05-08 | Santaris Pharma A/S | LNA oligonucleotides and the treatment of cancer |
US7589190B2 (en) | 2004-11-09 | 2009-09-15 | Enzon Pharmaceuticals, Inc. | Potent LNA oligonucleotides for the inhibition of HIF-1A expression |
US8410071B2 (en) | 2004-11-09 | 2013-04-02 | Santaris Pharma A/S | Potent LNA oligonucleotides for the inhibition of HIF-1A expression |
US9447138B2 (en) | 2004-11-09 | 2016-09-20 | Roche Innovation Center Copenhagen A/S | Potent LNA oligonucleotides for the inhibition of HIF-1a expression |
US9938527B2 (en) | 2004-11-09 | 2018-04-10 | Roche Innovation Center Copenhagen A/S | Potent LNA oligonucleotides for the inhibition of HIF-1A expression |
Also Published As
Publication number | Publication date |
---|---|
CZ218694A3 (en) | 1995-02-15 |
MX9301345A (es) | 1993-09-01 |
HU9402614D0 (en) | 1994-11-28 |
FR2688518B1 (fr) | 1994-05-06 |
RU94041682A (ru) | 1996-07-20 |
FI944190A0 (fi) | 1994-09-12 |
TW235961B (fr) | 1994-12-11 |
NO943371D0 (no) | 1994-09-12 |
CA2117552A1 (fr) | 1993-09-16 |
ZA931800B (en) | 1993-09-30 |
AU3756393A (en) | 1993-10-05 |
DE69300766D1 (de) | 1995-12-14 |
FR2688518A1 (fr) | 1993-09-17 |
GR3018036T3 (en) | 1996-02-29 |
DK0630428T3 (da) | 1995-12-27 |
JPH07504461A (ja) | 1995-05-18 |
NO943371L (no) | 1994-09-12 |
KR950700439A (ko) | 1995-01-16 |
DE69300766T2 (de) | 1996-04-18 |
EP0630428A1 (fr) | 1994-12-28 |
ES2079982T3 (es) | 1996-01-16 |
FI944190A (fi) | 1994-09-12 |
HUT68282A (en) | 1995-04-03 |
SK108494A3 (en) | 1995-02-08 |
ATE130053T1 (de) | 1995-11-15 |
EP0630428B1 (fr) | 1995-11-08 |
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