UY25201A1 - Método para tratar ácido 4-fenil-4-cianociclohexanoicos sustituidos - Google Patents

Método para tratar ácido 4-fenil-4-cianociclohexanoicos sustituidos

Info

Publication number
UY25201A1
UY25201A1 UY25201A UY25201A UY25201A1 UY 25201 A1 UY25201 A1 UY 25201A1 UY 25201 A UY25201 A UY 25201A UY 25201 A UY25201 A UY 25201A UY 25201 A1 UY25201 A1 UY 25201A1
Authority
UY
Uruguay
Prior art keywords
cr4r5
cyanociclohexanoic
phenyl
acid
alkyl
Prior art date
Application number
UY25201A
Other languages
English (en)
Spanish (es)
Inventor
Jian-Hoa Chen
Wilford Mendelson
Kevin Webb
Original Assignee
Smithkline Beckman Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beckman Corp filed Critical Smithkline Beckman Corp
Publication of UY25201A1 publication Critical patent/UY25201A1/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D303/00Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02Compounds containing oxirane rings
    • C07D303/48Compounds containing oxirane rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms, e.g. ester or nitrile radicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00Carboxylic acid nitriles
    • C07C255/45Carboxylic acid nitriles having cyano groups bound to carbon atoms of rings other than six-membered aromatic rings
    • C07C255/46Carboxylic acid nitriles having cyano groups bound to carbon atoms of rings other than six-membered aromatic rings to carbon atoms of non-condensed rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C07C45/70Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form
    • C07C45/71Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form being hydroxy groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C47/00Compounds having —CHO groups
    • C07C47/52Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings
    • C07C47/575Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings containing ether groups, groups, groups, or groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
    • C07C2601/06Systems containing only non-condensed rings with a five-membered ring
    • C07C2601/08Systems containing only non-condensed rings with a five-membered ring the ring being saturated
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
    • C07C2601/12Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14The ring being saturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pulmonology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
UY25201A 1997-10-10 1998-10-07 Método para tratar ácido 4-fenil-4-cianociclohexanoicos sustituidos UY25201A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US6161397P 1997-10-10 1997-10-10

Publications (1)

Publication Number Publication Date
UY25201A1 true UY25201A1 (es) 2001-08-27

Family

ID=22036929

Family Applications (2)

Application Number Title Priority Date Filing Date
UY25201A UY25201A1 (es) 1997-10-10 1998-10-07 Método para tratar ácido 4-fenil-4-cianociclohexanoicos sustituidos
UY25524A UY25524A1 (es) 1997-10-10 1999-05-25 Método para preparar ácidos 4-fenil4-cianociclohexanoicos sustituidos

Family Applications After (1)

Application Number Title Priority Date Filing Date
UY25524A UY25524A1 (es) 1997-10-10 1999-05-25 Método para preparar ácidos 4-fenil4-cianociclohexanoicos sustituidos

Country Status (30)

Country Link
EP (1) EP1043930A4 (xx)
JP (1) JP2001519363A (xx)
KR (1) KR100560038B1 (xx)
CN (1) CN1192025C (xx)
AP (1) AP1335A (xx)
AR (1) AR015952A1 (xx)
AU (1) AU741832B2 (xx)
BG (1) BG104302A (xx)
BR (1) BR9814064A (xx)
CA (1) CA2305614A1 (xx)
DZ (1) DZ2619A1 (xx)
EA (1) EA003609B1 (xx)
HU (1) HUP0003905A3 (xx)
ID (1) ID25536A (xx)
IL (1) IL135434A (xx)
MA (1) MA24670A1 (xx)
MY (1) MY122105A (xx)
NO (1) NO20001777L (xx)
NZ (1) NZ503759A (xx)
OA (1) OA11347A (xx)
PE (1) PE121599A1 (xx)
PL (1) PL191974B1 (xx)
SA (1) SA99191000A (xx)
SK (1) SK4902000A3 (xx)
TR (1) TR200000945T2 (xx)
TW (1) TW440557B (xx)
UA (1) UA67753C2 (xx)
UY (2) UY25201A1 (xx)
WO (1) WO1999018793A1 (xx)
ZA (1) ZA989228B (xx)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9920152D0 (en) * 1999-08-25 1999-10-27 Smithkline Beecham Plc Novel process
EP1237851A4 (en) * 1999-12-15 2004-06-23 Smithkline Beecham SALES OF I CIS / I-4-CYANO-4-3- (CYCLOPENTYLOXY) -4-METHOXYPHENYL] CYCLHEXAN-1-CARBONIC ACID
EP1250313B1 (en) * 2000-01-26 2006-11-02 SmithKline Beecham Corporation Monohydrate of cis-lithium-cyano-4- 3-(cyclopentyloxy)-4-methoxyphenyl|cyclohexanecarboxylate
EP2258689A1 (en) 2000-03-16 2010-12-08 Biolipox AB Benzylated PDE4 inhibitors
MXPA03006886A (es) 2001-01-31 2003-11-13 Pfizer Prod Inc Derivados amida de acido tiazolilico, oxazolilico, pirrolilico e imidazolilico utiles como inhibidores de las isozimas pde4.
IL156460A0 (en) 2001-01-31 2004-01-04 Pfizer Prod Inc Ether derivatives useful as inhibitors of pde4 isozymes
US7250518B2 (en) 2001-01-31 2007-07-31 Pfizer Inc. Nicotinamide acids, amides, and their mimetics active as inhibitors of PDE4 isozymes
CZ20031895A3 (cs) 2001-01-31 2004-08-18 Pfizeráproductsáinc Nikotinamidové biarylové deriváty užitečné jako inhibitory isozymů PDE
CN102491959B (zh) * 2011-12-19 2015-03-25 江苏澄扬作物科技有限公司 一种环氧乙烷衍生物的制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4021478A (en) * 1972-07-13 1977-05-03 The Upjohn Company Preparation of carboxylic acids from glycidonitriles with ionic lewis acids
US5552438A (en) * 1992-04-02 1996-09-03 Smithkline Beecham Corporation Compounds useful for treating allergic and inflammatory diseases
US5524438A (en) * 1994-12-15 1996-06-11 United Technologies Corporation Segmented bulkhead liner for a gas turbine combustor
UY24882A1 (es) * 1997-02-12 2001-08-27 Smithkline Beecham Corp Ácidos 4-fenil-4-ciano-ciclohexanoicos sustituidos
US6452022B1 (en) * 1997-10-10 2002-09-17 Smithkline Beecham Corporation Method for preparing substituted 4-phenyl-4-cyanocyclohexanoic acids

Also Published As

Publication number Publication date
DZ2619A1 (fr) 2003-03-08
ZA989228B (en) 1999-04-12
PL191974B1 (pl) 2006-07-31
AU9687498A (en) 1999-05-03
PL339759A1 (en) 2001-01-02
EA200000406A1 (ru) 2000-10-30
EP1043930A4 (en) 2004-09-15
AR015952A1 (es) 2001-05-30
EP1043930A1 (en) 2000-10-18
NZ503759A (en) 2002-03-01
AP2000001782A0 (en) 2000-06-30
IL135434A (en) 2004-12-15
HUP0003905A3 (en) 2002-01-28
SK4902000A3 (en) 2000-11-07
WO1999018793A1 (en) 1999-04-22
NO20001777D0 (no) 2000-04-06
EA003609B1 (ru) 2003-06-26
UA67753C2 (uk) 2004-07-15
SA99191000A (ar) 2005-12-03
KR100560038B1 (ko) 2006-03-13
KR20010015709A (ko) 2001-02-26
CN1192025C (zh) 2005-03-09
NO20001777L (no) 2000-05-03
HUP0003905A2 (en) 2001-03-28
AU741832B2 (en) 2001-12-13
TR200000945T2 (tr) 2000-10-23
PE121599A1 (es) 2000-02-19
MY122105A (en) 2006-03-31
CN1275052A (zh) 2000-11-29
BG104302A (en) 2001-08-31
AP1335A (en) 2004-11-29
UY25524A1 (es) 2000-02-23
OA11347A (en) 2003-12-17
ID25536A (id) 2000-10-12
IL135434A0 (en) 2001-05-20
JP2001519363A (ja) 2001-10-23
TW440557B (en) 2001-06-16
BR9814064A (pt) 2000-09-26
CA2305614A1 (en) 1999-04-22
MA24670A1 (fr) 1999-07-01

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Legal Events

Date Code Title Description
110 Patent granted

Effective date: 20100625

VENC Patent expired

Effective date: 20181007