US20110195107A1 - Method for manufacturing a porous three-dimensional scaffold using powder from animal tissue, and porous three-dimensional scaffold manufactured by same - Google Patents

Method for manufacturing a porous three-dimensional scaffold using powder from animal tissue, and porous three-dimensional scaffold manufactured by same Download PDF

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Publication number
US20110195107A1
US20110195107A1 US13/123,798 US200913123798A US2011195107A1 US 20110195107 A1 US20110195107 A1 US 20110195107A1 US 200913123798 A US200913123798 A US 200913123798A US 2011195107 A1 US2011195107 A1 US 2011195107A1
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United States
Prior art keywords
cartilage
tissue
animal
porous
powder
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US13/123,798
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English (en)
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Byoung-Hyun Min
Ji Wook Jang
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Ajou University Industry Academic Cooperation Foundation
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Ajou University Industry Academic Cooperation Foundation
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Assigned to AJOU UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION reassignment AJOU UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: JANG, JI WOOK, MIN, BYOUNG-HYUN
Publication of US20110195107A1 publication Critical patent/US20110195107A1/en
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3604—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3604—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
    • A61L27/3612—Cartilage, synovial fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3641—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the site of application in the body
    • A61L27/3645—Connective tissue
    • A61L27/3654—Cartilage, e.g. meniscus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3683—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
    • A61L27/3817—Cartilage-forming cells, e.g. pre-chondrocytes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3839—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by the site of application in the body
    • A61L27/3843—Connective tissue
    • A61L27/3852—Cartilage, e.g. meniscus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/56—Porous materials, e.g. foams or sponges
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00—Materials characterised by their function or physical properties
    • A61L2400/08—Methods for forming porous structures using a negative form which is filled and then removed by pyrolysis or dissolution
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00—Materials characterised by their function or physical properties
    • A61L2400/18—Modification of implant surfaces in order to improve biocompatibility, cell growth, fixation of biomolecules, e.g. plasma treatment
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/06—Materials or treatment for tissue regeneration for cartilage reconstruction, e.g. meniscus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/40—Preparation and treatment of biological tissue for implantation, e.g. decellularisation, cross-linking
US13/123,798 2008-10-13 2009-10-12 Method for manufacturing a porous three-dimensional scaffold using powder from animal tissue, and porous three-dimensional scaffold manufactured by same Abandoned US20110195107A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
KR1020080100005A KR101056069B1 (ko) 2008-10-13 2008-10-13 동물조직 분말을 이용한 다공성 3차원 지지체의 제조방법
KR10-2008-0100005 2008-10-13
PCT/KR2009/005839 WO2010044577A2 (ko) 2008-10-13 2009-10-12 동물조직 분말을 이용한 다공성 3차원 지지체의 제조방법 및 이를 이용하여 제조된 다공성 3차원 지지체

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US20110195107A1 true US20110195107A1 (en) 2011-08-11

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US13/123,798 Abandoned US20110195107A1 (en) 2008-10-13 2009-10-12 Method for manufacturing a porous three-dimensional scaffold using powder from animal tissue, and porous three-dimensional scaffold manufactured by same

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US (1) US20110195107A1 (zh)
EP (1) EP2345435B1 (zh)
JP (1) JP5483035B2 (zh)
KR (1) KR101056069B1 (zh)
CN (1) CN102238970B (zh)
WO (1) WO2010044577A2 (zh)

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WO2014145854A1 (en) * 2013-03-15 2014-09-18 University Of Florida Research Foundation, Inc. Method for decellularization of tissue grafts
WO2015035233A1 (en) * 2013-09-09 2015-03-12 Eran Rosines Biologic prosthesis and methods of production and use
WO2015048317A1 (en) * 2013-09-25 2015-04-02 The Children's Mercy Hospital Decellularized hyaline cartilage powder for tissue scaffolds
US20150182662A1 (en) * 2006-01-18 2015-07-02 Cormatrix Cardiovascular, Inc. Compositions and Methods for Treatment of Cardiovascular Disorders
CN104786277A (zh) * 2015-04-03 2015-07-22 中国人民解放军第三军医大学第一附属医院 软骨微粒获取装置
KR20160005712A (ko) * 2013-05-07 2016-01-15 고쿠리츠 다이가쿠호우징 도쿄이카시카다이가쿠 입자상 탈세포화 조직의 제조방법
CN107320778A (zh) * 2017-08-22 2017-11-07 广州赛莱拉干细胞科技股份有限公司 一种软骨脱细胞基质的制备方法
US10335515B2 (en) 2013-09-25 2019-07-02 The University Of Kansas Hydrogel precursors having nanoparticles
US10385311B2 (en) * 2015-05-27 2019-08-20 Purdue Research Foundation Method of making biological tissue components
CN110327495A (zh) * 2019-07-02 2019-10-15 上海国睿生命科技有限公司 组织工程耳廓形态复合支架及其制备方法
US10744228B2 (en) 2015-09-03 2020-08-18 The University Of Kansas Methacrylated devitalized cartilage and devitalized cartilage particles
US11052175B2 (en) 2015-08-19 2021-07-06 Musculoskeletal Transplant Foundation Cartilage-derived implants and methods of making and using same
CN114191612A (zh) * 2021-12-23 2022-03-18 南开大学 一种孔结构可控的细胞外基质支架制备方法及应用
CN114796616A (zh) * 2022-05-06 2022-07-29 广州医科大学附属第一医院（广州呼吸中心） 一种透明软骨脱细胞基质复合支架的制备方法
CN115944782A (zh) * 2022-11-07 2023-04-11 山东大学 一种骨膜脱细胞基质的方法

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KR101288088B1 (ko) * 2011-09-09 2013-07-22 아주대학교산학협력단 생체내 분해기간이 조절 가능한 생체적합성 소장점막하조직 하이드로젤의 제조방법
KR20130134447A (ko) * 2012-05-31 2013-12-10 리젠프라임 주식회사 신규한 나노섬유막 및 이의 제조방법
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KR101363573B1 (ko) * 2012-12-11 2014-02-21 가천대학교 산학협력단 관 형상의 생체적합성 및 생분해성 스캐폴드 제조방법
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WO2021172637A1 (ko) * 2020-02-28 2021-09-02 주식회사 엘앤씨바이오 연골 성분을 함유하는 연골 재생용 조성물 및 그 제조방법
KR102416861B1 (ko) * 2020-02-28 2022-07-07 주식회사 엘앤씨바이오 연골 성분을 함유하는 연골 재생용 조성물 및 그 제조방법
KR20220089586A (ko) 2020-12-21 2022-06-28 에이템즈 주식회사 복합기능성 유착방지용 약학조성물

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4656137A (en) * 1985-09-12 1987-04-07 Lescarden Inc Method of processing animal cartilage
US7201917B2 (en) * 2001-07-16 2007-04-10 Depuy Products, Inc. Porous delivery scaffold and method
US20070248638A1 (en) * 2006-04-21 2007-10-25 Van Dyke Mark E Structurally modified acellular tissue engineering scaffolds and methods of production
US20080124374A1 (en) * 2003-07-17 2008-05-29 Boston Scientific Scimed Decellularized bone marrow extracellular matrix

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5891558A (en) * 1994-11-22 1999-04-06 Tissue Engineering, Inc. Biopolymer foams for use in tissue repair and reconstruction
DE19855890A1 (de) * 1998-12-03 2000-06-08 Nerlich Michael Poröse Kompositmatrix, deren Herstellung und Verwendung
EP1416876B1 (en) * 2001-07-16 2011-03-23 DePuy Products, Inc. Porous delivery scaffold and method
US8728463B2 (en) * 2005-03-11 2014-05-20 Wake Forest University Health Science Production of tissue engineered digits and limbs

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4656137A (en) * 1985-09-12 1987-04-07 Lescarden Inc Method of processing animal cartilage
US7201917B2 (en) * 2001-07-16 2007-04-10 Depuy Products, Inc. Porous delivery scaffold and method
US20080124374A1 (en) * 2003-07-17 2008-05-29 Boston Scientific Scimed Decellularized bone marrow extracellular matrix
US20070248638A1 (en) * 2006-04-21 2007-10-25 Van Dyke Mark E Structurally modified acellular tissue engineering scaffolds and methods of production

Non-Patent Citations (12)

* Cited by examiner, † Cited by third party
Title
Barnes et al., Cross-Linking Electrospun Type II Collagen Tissue Engineering Scaffolds with carbodiimide in Ethanol, Tissue Engineering Volume 13, Number 7, 2007. *
Definition of "leaching": Merriam-webster Dictionary, downloaded online (12/29/2012). *
Draghi et al. Microspheres leaching for scaffold porosity, Journal of Materials Science: Materials in Medicine 16 (2005) 1093-1097. *
EDC: Sigma Aldrich, product specification. Downloaded online 01/08/2015. *
Jing et al., Solvent-Assisted Room- Temperature Compression Molding Approach to Fabricate Porous Scaffolds for Tissue Engineering, Macromol. Biosci. 2006, 6, 747-757. *
Jing et al., Solvent-assisted Room-Temperature Compression Molding Approach to Fabricate Porous Scaffolds for Tissue Engineering, DOI: 10.1002/mabi.200600079; May 30, 2006; 747-757. *
Kim et al., An in vivo study of the host tissue response to subcutaneous implantation of PLGA- and/or porcine small intestinal submucosa-based scaffolds, Biomaterials 28 (2007) 5137-5143. *
Ma et al., Enhanced biological stability of collagen porous scaffolds by using amino acids as novel cross-linking bridges, Biomaterials. *
Mano et al., Natural origin biodegradable systems in tissue engineering and regenerative medicine: present status and some moving trends, J. R. Soc. Interface (2007) 4, 999-1030. *
Wolfgang Friess, Collagen - biomaterial for drug delivery, European Journal of Pharmaceutics and Biopharmaceutics; 45 (1998) 113-136. *
Woodfield et al. Design of porous scaffolds for cartilage tissue engineering using a three-dimensional fiber-deposition technique, Biomaterials 25 (2004) 4149-4161. *
Yang et al. A cartilage ECM-derived 3-D porous acellular matrix scaffold for I vivo cartilage tissue engineering with PKH26-labled chondrogenic bone marrow-derived mesenchymal stem cells, Biomaterials 29 (2008) 2378-2387. *

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* Cited by examiner, † Cited by third party
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US9737569B2 (en) * 2006-01-18 2017-08-22 Cormatrix Cardiovascular, Inc. Compositions and methods for treatment of cardiovascular disorders
US20150182662A1 (en) * 2006-01-18 2015-07-02 Cormatrix Cardiovascular, Inc. Compositions and Methods for Treatment of Cardiovascular Disorders
US9572911B2 (en) 2013-03-15 2017-02-21 University Of Florida Research Foundation, Incorporated Method for decellularization of tissue grafts
WO2014145854A1 (en) * 2013-03-15 2014-09-18 University Of Florida Research Foundation, Inc. Method for decellularization of tissue grafts
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US20160058910A1 (en) * 2013-05-07 2016-03-03 Natiional University Corporation Tokyo Medical And Dental University Method for preparing particulate decellularized tissue
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WO2015035233A1 (en) * 2013-09-09 2015-03-12 Eran Rosines Biologic prosthesis and methods of production and use
US10814035B2 (en) 2013-09-09 2020-10-27 Eran Rosines Biological prosthesis and methods of production and use
KR102131872B1 (ko) 2013-09-09 2020-08-05 에란 로지네스 생물학적 보철물, 및 제조 및 사용 방법
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US11801330B2 (en) 2013-09-09 2023-10-31 Rosivo Llc Biological prosthesis and methods of production and use
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US11000630B2 (en) 2013-09-25 2021-05-11 The University Of Kansas Hydrogel precursors having nanoparticles
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