US20110033839A1 - Methods of Detecting Signatures of Disease or Conditions in Bodily Fluids - Google Patents
Methods of Detecting Signatures of Disease or Conditions in Bodily Fluids Download PDFInfo
- Publication number
- US20110033839A1 US20110033839A1 US12/836,191 US83619110A US2011033839A1 US 20110033839 A1 US20110033839 A1 US 20110033839A1 US 83619110 A US83619110 A US 83619110A US 2011033839 A1 US2011033839 A1 US 2011033839A1
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- cancer
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
- G01N33/5023—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects on expression patterns
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
- G01N33/5047—Cells of the immune system
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- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
- G01N33/5047—Cells of the immune system
- G01N33/505—Cells of the immune system involving T-cells
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- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
- G01N33/5047—Cells of the immune system
- G01N33/5052—Cells of the immune system involving B-cells
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- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
- G01N33/5047—Cells of the immune system
- G01N33/5055—Cells of the immune system involving macrophages
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- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5091—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing the pathological state of an organism
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56966—Animal cells
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57407—Specifically defined cancers
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- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57407—Specifically defined cancers
- G01N33/57434—Specifically defined cancers of prostate
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57407—Specifically defined cancers
- G01N33/57449—Specifically defined cancers of ovaries
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2563/00—Nucleic acid detection characterized by the use of physical, structural and functional properties
- C12Q2563/107—Nucleic acid detection characterized by the use of physical, structural and functional properties fluorescence
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2570/00—Omics, e.g. proteomics, glycomics or lipidomics; Methods of analysis focusing on the entire complement of classes of biological molecules or subsets thereof, i.e. focusing on proteomes, glycomes or lipidomes
Priority Applications (7)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US12/836,191 US20110033839A1 (en) | 2008-01-18 | 2010-07-14 | Methods of Detecting Signatures of Disease or Conditions in Bodily Fluids |
US13/349,670 US20130023426A1 (en) | 2008-01-18 | 2012-01-13 | Methods of Detecting Signatures of Disease or Conditions in Bodily Fluids |
US14/982,663 US10934588B2 (en) | 2008-01-18 | 2015-12-29 | Methods of detecting signatures of disease or conditions in bodily fluids |
US15/069,173 US20160195516A1 (en) | 2008-01-18 | 2016-03-14 | Methods of Detecting Signatures of Disease or Conditions in Bodily Fluids |
US15/338,786 US10934589B2 (en) | 2008-01-18 | 2016-10-31 | Methods of detecting signatures of disease or conditions in bodily fluids |
US15/617,577 US11001894B2 (en) | 2008-01-18 | 2017-06-08 | Methods of detecting signatures of disease or conditions in bodily fluids |
US17/233,625 US20210238697A1 (en) | 2008-01-18 | 2021-04-19 | Methods of detecting signatures of disease or conditions in bodily fluids |
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US2203308P | 2008-01-18 | 2008-01-18 | |
US7343408P | 2008-06-18 | 2008-06-18 | |
PCT/US2009/031395 WO2009092068A1 (en) | 2008-01-18 | 2009-01-19 | Methods of detecting signatures of disease or conditions in bodily fluids |
US12/836,191 US20110033839A1 (en) | 2008-01-18 | 2010-07-14 | Methods of Detecting Signatures of Disease or Conditions in Bodily Fluids |
Related Parent Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2009/031395 Continuation WO2009092068A1 (en) | 2008-01-18 | 2009-01-19 | Methods of detecting signatures of disease or conditions in bodily fluids |
PCT/US2009/031395 Continuation-In-Part WO2009092068A1 (en) | 2008-01-18 | 2009-01-19 | Methods of detecting signatures of disease or conditions in bodily fluids |
Related Child Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US13/349,670 Division US20130023426A1 (en) | 2008-01-18 | 2012-01-13 | Methods of Detecting Signatures of Disease or Conditions in Bodily Fluids |
US14/982,663 Continuation US10934588B2 (en) | 2008-01-18 | 2015-12-29 | Methods of detecting signatures of disease or conditions in bodily fluids |
Publications (1)
Publication Number | Publication Date |
---|---|
US20110033839A1 true US20110033839A1 (en) | 2011-02-10 |
Family
ID=40885676
Family Applications (7)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US12/836,191 Abandoned US20110033839A1 (en) | 2008-01-18 | 2010-07-14 | Methods of Detecting Signatures of Disease or Conditions in Bodily Fluids |
US13/349,670 Abandoned US20130023426A1 (en) | 2008-01-18 | 2012-01-13 | Methods of Detecting Signatures of Disease or Conditions in Bodily Fluids |
US14/982,663 Active 2029-04-13 US10934588B2 (en) | 2008-01-18 | 2015-12-29 | Methods of detecting signatures of disease or conditions in bodily fluids |
US15/069,173 Abandoned US20160195516A1 (en) | 2008-01-18 | 2016-03-14 | Methods of Detecting Signatures of Disease or Conditions in Bodily Fluids |
US15/338,786 Active US10934589B2 (en) | 2008-01-18 | 2016-10-31 | Methods of detecting signatures of disease or conditions in bodily fluids |
US15/617,577 Active 2029-06-03 US11001894B2 (en) | 2008-01-18 | 2017-06-08 | Methods of detecting signatures of disease or conditions in bodily fluids |
US17/233,625 Abandoned US20210238697A1 (en) | 2008-01-18 | 2021-04-19 | Methods of detecting signatures of disease or conditions in bodily fluids |
Family Applications After (6)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US13/349,670 Abandoned US20130023426A1 (en) | 2008-01-18 | 2012-01-13 | Methods of Detecting Signatures of Disease or Conditions in Bodily Fluids |
US14/982,663 Active 2029-04-13 US10934588B2 (en) | 2008-01-18 | 2015-12-29 | Methods of detecting signatures of disease or conditions in bodily fluids |
US15/069,173 Abandoned US20160195516A1 (en) | 2008-01-18 | 2016-03-14 | Methods of Detecting Signatures of Disease or Conditions in Bodily Fluids |
US15/338,786 Active US10934589B2 (en) | 2008-01-18 | 2016-10-31 | Methods of detecting signatures of disease or conditions in bodily fluids |
US15/617,577 Active 2029-06-03 US11001894B2 (en) | 2008-01-18 | 2017-06-08 | Methods of detecting signatures of disease or conditions in bodily fluids |
US17/233,625 Abandoned US20210238697A1 (en) | 2008-01-18 | 2021-04-19 | Methods of detecting signatures of disease or conditions in bodily fluids |
Country Status (18)
Country | Link |
---|---|
US (7) | US20110033839A1 (pt) |
EP (3) | EP3358354B1 (pt) |
JP (6) | JP5781767B2 (pt) |
KR (7) | KR101815138B1 (pt) |
CN (3) | CN107119108A (pt) |
AU (1) | AU2009205956B2 (pt) |
BR (2) | BR122018069446B8 (pt) |
CA (2) | CA2878025C (pt) |
DK (1) | DK2240781T3 (pt) |
EA (2) | EA020920B1 (pt) |
ES (2) | ES2809171T3 (pt) |
HK (2) | HK1243737A1 (pt) |
IL (4) | IL207027A0 (pt) |
MX (2) | MX340916B (pt) |
NZ (2) | NZ586834A (pt) |
PT (1) | PT2240781T (pt) |
SG (2) | SG10201704689XA (pt) |
WO (1) | WO2009092068A1 (pt) |
Cited By (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2012012725A3 (en) * | 2010-07-23 | 2012-04-26 | President And Fellows Of Harvard College | Methods of detecting diseases or conditions using phagocytic cells |
US20170097355A1 (en) * | 2015-10-06 | 2017-04-06 | University Of Washington | Biomarkers and methods to distinguish ovarian cancer from benign tumors |
US10494675B2 (en) | 2013-03-09 | 2019-12-03 | Cell Mdx, Llc | Methods of detecting cancer |
US10934589B2 (en) | 2008-01-18 | 2021-03-02 | President And Fellows Of Harvard College | Methods of detecting signatures of disease or conditions in bodily fluids |
US10961578B2 (en) | 2010-07-23 | 2021-03-30 | President And Fellows Of Harvard College | Methods of detecting prenatal or pregnancy-related diseases or conditions |
US11111537B2 (en) | 2010-07-23 | 2021-09-07 | President And Fellows Of Harvard College | Methods of detecting autoimmune or immune-related diseases or conditions |
Families Citing this family (29)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2012520469A (ja) | 2009-03-12 | 2012-09-06 | キャンサー・プリヴェンション・アンド・キュア,リミテッド | 性別に基づく疾病の識別・評価・予防及び治療を含む、肺病の識別・評価・予防及び治療の方法並びにそのキット |
WO2012012704A2 (en) * | 2010-07-23 | 2012-01-26 | President And Fellows Of Harvard College | Methods of detecting kidney-associated diseases or conditions |
CA2806301A1 (en) * | 2010-07-23 | 2012-01-26 | President And Fellows Of Harvard College | Methods of detecting cardiovascular diseases or conditions |
WO2012012714A2 (en) * | 2010-07-23 | 2012-01-26 | President And Fellows Of Harvard College | Methods of detecting neurological or neuropsychiatric diseases or conditions |
MX361944B (es) * | 2010-07-23 | 2018-12-19 | President And Fellows Of Harvard College Star | Metodos para detectar firmas de enfermedad o condiciones en fluidos corporales. |
US20140057262A1 (en) * | 2011-03-14 | 2014-02-27 | Mayo Foundation For Medical Education And Research | Methods and materials for using the contents of phagocytes to detect neoplasms |
CN103703371A (zh) | 2011-04-29 | 2014-04-02 | 癌症预防和治疗有限公司 | 使用分类系统及其试剂盒识别和诊断肺部疾病的方法 |
CN106940268B (zh) * | 2012-02-23 | 2021-09-21 | 朱诺治疗有限公司 | 细胞和其它复杂生物材料的色谱分离 |
US11156596B2 (en) | 2012-06-01 | 2021-10-26 | Creatv Microtech, Inc. | Capture, identification and use of a new biomarker of solid tumors in body fluids |
CA2874691C (en) * | 2012-06-01 | 2021-08-24 | Creatv Microtech, Inc. | Capture, identification and use of a new biomarker of solid tumors in body fluids |
KR20150035821A (ko) * | 2012-06-15 | 2015-04-07 | 해리 스타일리 | 질환 또는 병태를 검출하는 방법 |
US11585814B2 (en) | 2013-03-09 | 2023-02-21 | Immunis.Ai, Inc. | Methods of detecting prostate cancer |
WO2015095359A1 (en) * | 2013-12-17 | 2015-06-25 | Harry Stylli | Methods of detecting diseases or conditions |
DE102014206441A1 (de) * | 2014-04-03 | 2015-10-08 | Siemens Aktiengesellschaft | Verfahren für die Molekulardiagnostik zum Anreichern einer Nukleinsäure aus einer biologischen Probe |
WO2015128396A1 (de) * | 2014-02-26 | 2015-09-03 | Siemens Aktiengesellschaft | Verfahren für die molekulardiagnostik zum anreichern einer nukleinsäure aus einer biologischen probe |
MY184699A (en) | 2014-04-16 | 2021-04-18 | Juno Therapeutics Gmbh | Methods, kits and apparatus for expanding a population of cells |
US10871491B2 (en) | 2014-08-25 | 2020-12-22 | Creatv Microtech, Inc. | Use of circulating cell biomarkers in the blood for detection and diagnosis of diseases and methods of isolating them |
WO2016040843A1 (en) * | 2014-09-11 | 2016-03-17 | Harry Stylli | Methods of detecting prostate cancer |
GB2594421A (en) * | 2015-03-06 | 2021-10-27 | Micromass Ltd | Inlet instrumentation for ion analyser coupled to rapid evaporative ionisation mass spectrometry ("REIMS") device |
MA45488A (fr) | 2015-10-22 | 2018-08-29 | Juno Therapeutics Gmbh | Procédés, kits et appareil de culture de cellules |
MA45489A (fr) | 2015-10-22 | 2018-08-29 | Juno Therapeutics Gmbh | Procédés de culture de cellules, kits et appareil associés |
RU2021134624A (ru) | 2015-10-22 | 2022-03-15 | Джуно Терапьютикс Гмбх | Способы, наборы, средства и устройства для трансдукции |
US20190071795A1 (en) * | 2016-03-09 | 2019-03-07 | Molecular Stethoscope, Inc. | Methods and systems for detecting tissue conditions |
WO2018187496A2 (en) | 2017-04-04 | 2018-10-11 | Lung Cancer Proteomics, Llc | Plasma based protein profiling for early stage lung cancer prognosis |
KR102606210B1 (ko) | 2017-04-27 | 2023-11-24 | 주노 테라퓨틱스 게엠베하 | 올리고머 입자 시약 및 이의 사용 방법 |
WO2019046814A1 (en) | 2017-09-01 | 2019-03-07 | Venn Biosciences Corporation | IDENTIFICATION AND USE OF GLYCOPEPTIDES AS BIOMARKERS FOR THE DIAGNOSIS AND MONITORING OF TREATMENT |
JP2021500539A (ja) * | 2017-10-18 | 2021-01-07 | ヴェン バイオサイエンシズ コーポレーション | 診断及び治療モニタリングのための生体パラメータの同定及び使用 |
WO2020028456A1 (en) * | 2018-07-31 | 2020-02-06 | Cell Mdx, Llc | Compositions and methods for detecting prostate cancer |
CN109207425A (zh) * | 2018-09-29 | 2019-01-15 | 中国医科大学附属口腔医院 | 牙龈卟啉单胞菌诱导巨噬细胞外泌体rna表达研究方法 |
Citations (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4814434A (en) * | 1984-02-03 | 1989-03-21 | Ventres Laboratories, Inc. | Inducer of T-suppressor cells |
US5043267A (en) * | 1984-05-18 | 1991-08-27 | E. I. Du Pont De Nemours And Company | Method for rapid detection of bacterial and fungal infection |
US6117985A (en) * | 1995-06-16 | 2000-09-12 | Stemcell Technologies Inc. | Antibody compositions for preparing enriched cell preparations |
US20010051344A1 (en) * | 1994-06-17 | 2001-12-13 | Shalon Tidhar Dari | Methods for constructing subarrays and uses thereof |
US20060088836A1 (en) * | 2002-04-24 | 2006-04-27 | Jay Wohlgemuth | Methods and compositions for diagnosing and monitoring transplant rejection |
US20060094067A1 (en) * | 2002-06-26 | 2006-05-04 | Ralf Herwig | Method for the determination of characteristics and/or the classification of circulating macrophages, and analysis arrangement for carrying out said method |
US20060115832A1 (en) * | 2002-11-14 | 2006-06-01 | Jon Wayne Cancer Institute | Detection of cancer cells in body fluids |
US20070015172A1 (en) * | 2005-06-01 | 2007-01-18 | Z-Biomed, Inc. | Expression profiles for microbial infection |
US20070099209A1 (en) * | 2005-06-13 | 2007-05-03 | The Regents Of The University Of Michigan | Compositions and methods for treating and diagnosing cancer |
US20070134689A1 (en) * | 2005-09-28 | 2007-06-14 | National Taiwan University | Tumor marker for ovarian cancer diagnosis |
Family Cites Families (266)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4683195A (en) | 1986-01-30 | 1987-07-28 | Cetus Corporation | Process for amplifying, detecting, and/or-cloning nucleic acid sequences |
US4683202A (en) | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
US4868103A (en) | 1986-02-19 | 1989-09-19 | Enzo Biochem, Inc. | Analyte detection by means of energy transfer |
US4843155A (en) | 1987-11-19 | 1989-06-27 | Piotr Chomczynski | Product and process for isolating RNA |
US5077216A (en) | 1988-07-06 | 1991-12-31 | The Trustees Of Dartmouth College | Monoclonal antibodies specific for a human mononculear phagocyte-specific antigen |
US5459039A (en) | 1989-05-12 | 1995-10-17 | Duke University | Methods for mapping genetic mutations |
EP0552108B1 (en) | 1992-01-17 | 1999-11-10 | Lakowicz, Joseph R. | Energy transfer phase-modulation fluoro-immunoassay |
DE69433811T2 (de) | 1993-01-07 | 2005-06-23 | Sequenom, Inc., San Diego | Dns - sequenzierung durch massenspektronomie |
GB2291059B (en) | 1993-03-19 | 1997-09-24 | North Sydney Area Health Serv | Papp-a,its immunodetection and uses |
US5594637A (en) | 1993-05-26 | 1997-01-14 | Base Ten Systems, Inc. | System and method for assessing medical risk |
US5498531A (en) | 1993-09-10 | 1996-03-12 | President And Fellows Of Harvard College | Intron-mediated recombinant techniques and reagents |
US5514598A (en) | 1993-11-30 | 1996-05-07 | Doody; Michael | Prenatal detection of meconium |
US6025395A (en) | 1994-04-15 | 2000-02-15 | Duke University | Method of preventing or delaying the onset and progression of Alzheimer's disease and related disorders |
US5854033A (en) | 1995-11-21 | 1998-12-29 | Yale University | Rolling circle replication reporter systems |
US6031088A (en) | 1996-05-23 | 2000-02-29 | Albert Einstein College Of Medicine Of Yeshiva University | Polycystic kidney disease PKD2 gene and uses thereof |
US20030044859A1 (en) | 1996-08-19 | 2003-03-06 | Henslee Jerry G. | Reagents and methods useful for detecting diseases of the breast |
US20010051341A1 (en) | 1997-03-04 | 2001-12-13 | Isis Innovation Limited | Non-invasive prenatal diagnosis |
GB9704444D0 (en) | 1997-03-04 | 1997-04-23 | Isis Innovation | Non-invasive prenatal diagnosis |
US20020119118A1 (en) | 1997-11-03 | 2002-08-29 | Genentech, Inc. | Novel polypeptides and nucleic acids encoding bolekine |
JPH11118792A (ja) * | 1997-10-17 | 1999-04-30 | Ajinomoto Co Inc | マクロファージの分類方法、免疫性疾患等の検定方法及び免疫性疾患治療剤のスクリーニング方法 |
JP3301963B2 (ja) * | 1998-04-14 | 2002-07-15 | 和久 鍬田 | 重症化侵襲のスクリーニング方法 |
CA2359816C (en) | 1999-01-06 | 2010-08-03 | Genenews Inc. | Method for the detection of gene transcripts in blood and uses thereof |
US6762032B1 (en) | 1999-08-23 | 2004-07-13 | Biocrystal, Ltd. | Compositions, assay kits, and methods for use related to a disease condition comprising multiple sclerosis and/or a pro-MS immune response |
AU2001275346A1 (en) | 2000-06-05 | 2001-12-17 | General Hospital Corporation | Compositions, kits, and methods for identification and modulation of type i diabetes |
ES2291246T3 (es) | 2000-06-27 | 2008-03-01 | Von Recklinghausen Gesellschaft E.V. | Procedimiento para adquirir datos para el diagnostico presintomatico o prenatal de neurofribromatosis del tipo 1. |
US6631330B1 (en) | 2000-08-21 | 2003-10-07 | Assistance Publique-Hopitaux De Paris (Ap-Hp) | Diagnosis method of inflammatory, fibrotic or cancerous disease using biochemical markers |
AU2126502A (en) * | 2000-10-03 | 2002-04-15 | Gene Logic, Inc. | Gene expression profiles in granulocytic cells |
US6664056B2 (en) | 2000-10-17 | 2003-12-16 | The Chinese University Of Hong Kong | Non-invasive prenatal monitoring |
EP1436413A2 (en) * | 2000-10-24 | 2004-07-14 | Whitehead Institute For Biomedical Research | Response of dendritic cells to a diverse set of pathogens |
FR2816411B1 (fr) | 2000-11-03 | 2003-07-04 | Inst Nat Sante Rech Med | Moyens de detection de la transformation pathologique de la proteine app et leurs applications |
EP1351707B9 (en) | 2001-01-09 | 2012-01-25 | Baylor Research Institute | Methods for treating autoimmune diseases in a subject and in vitro diagnostic assays |
WO2002061434A2 (en) | 2001-01-29 | 2002-08-08 | The Center For Blood Research, Inc | Anergy-regulated molecules |
US6753137B2 (en) | 2001-01-31 | 2004-06-22 | The Chinese University Of Hong Kong | Circulating epstein-barr virus DNA in the serum of patients with gastric carcinoma |
GB0104690D0 (en) | 2001-02-26 | 2001-04-11 | Cytogenetic Dna Services Ltd | Diagnostic test |
FR2824144B1 (fr) | 2001-04-30 | 2004-09-17 | Metagenex S A R L | Methode de diagnostic prenatal sur cellule foetale isolee du sang maternel |
CA2446666A1 (en) | 2001-05-09 | 2002-11-14 | Biovision Ag | Method for detecting progredient chronic dementia, and associated peptides and detection reagents |
US6905827B2 (en) | 2001-06-08 | 2005-06-14 | Expression Diagnostics, Inc. | Methods and compositions for diagnosing or monitoring auto immune and chronic inflammatory diseases |
WO2003019193A1 (en) | 2001-08-30 | 2003-03-06 | Ciphergen Biosystems, Inc. | Method of diagnosing nephrotic syndrome |
US6927028B2 (en) | 2001-08-31 | 2005-08-09 | Chinese University Of Hong Kong | Non-invasive methods for detecting non-host DNA in a host using epigenetic differences between the host and non-host DNA |
US20040038201A1 (en) * | 2002-01-22 | 2004-02-26 | Whitehead Institute For Biomedical Research | Diagnostic and therapeutic applications for biomarkers of infection |
US6986995B2 (en) | 2002-02-28 | 2006-01-17 | Prometheus Laboratories, Inc. | Methods of diagnosing liver fibrosis |
US7744876B2 (en) | 2002-04-09 | 2010-06-29 | The Curators Of The University Of Missouri | Methods and compositions for treatment, prevention, suppression, and/or delaying the onset of type 1 diabetes |
US7009038B2 (en) | 2002-05-02 | 2006-03-07 | Univ. Of Medicine & Dentistry Of N.J. | pDJA1, a cardiac specific gene, corresponding proteins, and uses thereof |
CN102533972B (zh) | 2002-05-09 | 2014-07-02 | 布赖汉姆妇女医院 | 作为心血管病的标志和治疗靶的1l1rl-1 |
US20040009518A1 (en) | 2002-05-14 | 2004-01-15 | The Chinese University Of Hong Kong | Methods for evaluating a disease condition by nucleic acid detection and fractionation |
US7157235B2 (en) | 2002-06-17 | 2007-01-02 | St. Vincent's Hospital Sydney Limited | Methods of diagnosis, prognosis and treatment of cardiovascular disease |
EP1520172A1 (en) | 2002-07-05 | 2005-04-06 | EVOTEC Neurosciences GmbH | Diagnostic and therapeutic use of tb2 gene and protein for neurodegenerative diseases |
FR2844279A1 (fr) | 2002-09-06 | 2004-03-12 | Inst Nat Sante Rech Med | Moyens de detection des processus neurodegeneratifs et leurs applications |
WO2004024098A2 (en) | 2002-09-16 | 2004-03-25 | Abgenix, Inc. | Method for the treatment of nephritis using anti-pdgf-dd antibodies |
DE60333500D1 (de) | 2002-10-02 | 2010-09-02 | Hoffmann La Roche | Verfahren zur Identifizierung antigener Peptide |
CA2500652A1 (en) | 2002-10-02 | 2004-04-15 | Dmi Biosciences, Inc. | Diagnosis and monitoring of diseases |
US20040086864A1 (en) | 2002-10-22 | 2004-05-06 | The Chinese University Of Hong Kong | Novel classification methods for pleural effusions |
GB0225360D0 (en) | 2002-10-31 | 2002-12-11 | Univ London | Genetic markers |
MXPA05005283A (es) * | 2002-11-21 | 2005-07-25 | Wyeth Corp | Metodos para diagnostico de rcc y otros tumores solidos. |
AU2002952993A0 (en) | 2002-11-29 | 2002-12-12 | The Corporation Of The Trustees Of The Order Of The Sisters Of Mercy In Queensland | Therapeutic and diagnostic agents |
CA2513292C (en) | 2003-01-17 | 2016-04-05 | The Chinese University Of Hong Kong | Circulating mrna as diagnostic markers for pregnancy-related disorders |
EP1590673B1 (en) | 2003-02-04 | 2009-04-15 | EVOTEC Neurosciences GmbH | Diagnostic use of scn2b for alzheimer's disease |
US20080107600A1 (en) | 2003-02-13 | 2008-05-08 | Taiichi Katayama | Gene Marker And Composition For Diagnosis And Treatment Of Neurological Disorders And Diseases And Use Of The Same |
US20040191818A1 (en) | 2003-02-26 | 2004-09-30 | O'toole Margot Mary | Compositions and methods for diagnosing and treating autoimmune diseases |
CA2517802A1 (en) | 2003-03-03 | 2004-09-16 | Arizona Board Of Regents On Behalf Of The University Of Arizona | Protein tyrosine phosphatase-prl-1 a a marker and therapeutic target for pancreatic cancer |
WO2005020784A2 (en) * | 2003-05-23 | 2005-03-10 | Mount Sinai School Of Medicine Of New York University | Surrogate cell gene expression signatures for evaluating the physical state of a subject |
WO2005094200A2 (en) | 2003-06-20 | 2005-10-13 | University Of Florida | Biomarkers for differentiating between type 2 and type 2 diabetes |
DE10333406A1 (de) | 2003-07-15 | 2005-02-10 | Protagen Ag | T-regulatorische-Zellen enthaltend Galectine zur Therapie und Diagnose von Erkrankungen |
WO2005012907A1 (en) | 2003-08-01 | 2005-02-10 | Renovar, Inc. | Systems and methods for characterizing kidney diseases |
WO2005017192A2 (en) | 2003-08-14 | 2005-02-24 | The General Hospital Corporation | Screening for gestational disorders |
AU2004270220B2 (en) | 2003-09-05 | 2009-03-05 | The Chinese University Of Hong Kong | Method for non-invasive prenatal diagnosis |
US7445886B2 (en) | 2003-09-10 | 2008-11-04 | Board Of Regents, The University Of Texas System | Macrophage migration inhibitory factor as a marker for cardiovascular risk |
US20050181386A1 (en) | 2003-09-23 | 2005-08-18 | Cornelius Diamond | Diagnostic markers of cardiovascular illness and methods of use thereof |
AU2004278782A1 (en) | 2003-10-03 | 2005-04-14 | Government Of The United States Of America Represented By The Secretary, Department Of Health And Human Services | Use of Cripto-1 as a biomarker for neurodegenerative disease and method of inhibiting progression thereof |
WO2005035725A2 (en) | 2003-10-08 | 2005-04-21 | The Trustees Of Boston University | Methods for prenatal diagnosis of chromosomal abnormalities |
DE60328193D1 (de) | 2003-10-16 | 2009-08-13 | Sequenom Inc | Nicht invasiver Nachweis fötaler genetischer Merkmale |
US7670764B2 (en) | 2003-10-24 | 2010-03-02 | Prometheus Laboratories Inc. | Methods of diagnosing tissue fibrosis |
JP2007513337A (ja) | 2003-11-19 | 2007-05-24 | サトリス, インコーポレイテッド | アルツハイマー病の診断方法、層化方法およびモニタリング方法 |
US20060094064A1 (en) | 2003-11-19 | 2006-05-04 | Sandip Ray | Methods and compositions for diagnosis, stratification, and monitoring of alzheimer's disease and other neurological disorders in body fluids |
WO2005050222A1 (en) | 2003-11-19 | 2005-06-02 | Evotec Neurosciences Gmbh | Diagnostic and therapeutic use of the human sgpl1 gene and protein for neurodegenerative diseases |
WO2005072340A2 (en) | 2004-01-27 | 2005-08-11 | Compugen Ltd. | Novel polynucleotides encoding polypeptides and methods using same |
EP1711633A1 (en) | 2004-02-04 | 2006-10-18 | EVOTEC Neurosciences GmbH | Diagnostic and therapeutic use of the kcne4 gene and protein for alzheimer disease |
WO2005082110A2 (en) | 2004-02-26 | 2005-09-09 | Illumina Inc. | Haplotype markers for diagnosing susceptibility to immunological conditions |
DE102004016437A1 (de) | 2004-04-04 | 2005-10-20 | Oligene Gmbh | Verfahren zur Erkennung von Signaturen in komplexen Genexpressionsprofilen |
US8071552B2 (en) | 2004-04-05 | 2011-12-06 | Universite Bordeaux 2 | Peptides and peptidomimetics binding to CD23 |
US20080051334A1 (en) | 2004-04-16 | 2008-02-28 | Evotec Neurosciences Gmbh | Diagnostic and Therapeutic Use of Kcnc1 for Neurodegenerative Diseases |
US7838245B2 (en) | 2004-04-20 | 2010-11-23 | Sphingotec Gmbh | Use of precursors of tachykinins and/or their fragments in medical diagnostic |
US20090041862A1 (en) | 2004-05-07 | 2009-02-12 | Peter Robert Schofield | Detecting disease association with aberrant glycogen synthase kinase 3beta expression |
JP2007535959A (ja) | 2004-05-10 | 2007-12-13 | エボテツク・ニユーロサイエンシーズ・ゲー・エム・ベー・ハー | アルツハイマー病のためのkcnj6の診断および治療使用 |
DE602005026931D1 (de) | 2004-05-13 | 2011-04-28 | Brahms Gmbh | Verwendung von vorstufen von enkephalinen und/oder deren fragmenten in der medizinischen diagnostik |
WO2005113828A1 (en) * | 2004-05-14 | 2005-12-01 | King Pharmaceuticals Research & Development, Inc. | Methods of diagnosing and prognosticating solid tumors and melanoma |
US7678544B2 (en) | 2004-05-19 | 2010-03-16 | Statens Serum Institut | ADAM12, a novel marker for abnormal cell function |
US7709194B2 (en) | 2004-06-04 | 2010-05-04 | The Chinese University Of Hong Kong | Marker for prenatal diagnosis and monitoring |
CN101137903A (zh) | 2004-07-19 | 2008-03-05 | 罗彻斯特大学 | 神经变性疾病的生物标记 |
US20060024757A1 (en) | 2004-07-30 | 2006-02-02 | Robert Hussa | Detection of oncofetal fibronectin for selection of concepti |
EP1789798A4 (en) | 2004-08-13 | 2009-02-18 | Xceed Molecular Corp | MARKER FOR DETECTION OF AUTOIMMUNE DISEASES |
US7833795B2 (en) | 2004-08-24 | 2010-11-16 | The Trustees Of The University Of Pennsylvania | Assessment of cardiovascular risk using isoprostane biomarkers and COX-2 selective inhibitors |
US20070087376A1 (en) | 2004-08-30 | 2007-04-19 | Potashkin Judith A | Splice variants of pre-mRNA transcripts as biomarkers in idiopathic neurodegenerative diseases |
WO2006032126A1 (en) | 2004-09-24 | 2006-03-30 | Syn X Pharma, Inc. | Diagnosis and treatment of early pre-type-1 diabetes utilizing neuronal proteins |
WO2006050475A2 (en) | 2004-11-03 | 2006-05-11 | Brigham And Women's Hospital, Inc. | Identification of dysregulated genes in patients with neurological diseases |
WO2006048778A1 (en) | 2004-11-08 | 2006-05-11 | King's College London | Markers of predisposition to addictive states |
US20060115854A1 (en) | 2004-12-01 | 2006-06-01 | Power3 Medical Products, Inc. | Acetyl-LDL receptor related proteins and peptides as a biomarker for neurodegenerative disease |
US20060115855A1 (en) | 2004-12-01 | 2006-06-01 | Power3 Medical Products, Inc. | FK506-binding protein 7 related protein as a biomarker for neurodegenerative disease |
CA2590781A1 (en) | 2004-12-07 | 2006-06-15 | Electrophoretics Limited | Diagnosis of neurodegenerative diseases |
GB0426859D0 (en) | 2004-12-07 | 2005-01-12 | Proteome Sciences Plc | Diagnosis of neurodegenerative disorders |
AU2005323025A1 (en) | 2004-12-31 | 2006-07-13 | Biogen Idec Ma Inc. | Polypeptides that bind BR3 and uses thereof |
FR2880897B1 (fr) | 2005-01-18 | 2010-12-17 | Inst Nat Sante Rech Med | Methode de detection, non invasive, prenatale, in vitro de l'etat sain normal, de l'etat de porteur sain ou de l'etat de porteur malade de la mucoviscidose |
US7432107B2 (en) | 2005-01-24 | 2008-10-07 | Roche Diagnostics Operations, Inc. | Cardiac hormones for assessing cardiovascular risk |
US20060172429A1 (en) | 2005-01-31 | 2006-08-03 | Nilsson Erik J | Methods of identification of biomarkers with mass spectrometry techniques |
US7572592B2 (en) | 2005-01-31 | 2009-08-11 | Glycominds Ltd | Method for diagnosing multiple sclerosis |
US20070141625A1 (en) | 2005-02-03 | 2007-06-21 | Santos Jose H | Method for assessing risk of and predisposition to development of a pathology related to the presence of anti-epcr autoantibodies |
ITRM20050067A1 (it) | 2005-02-17 | 2006-08-18 | Istituto Naz Per Le Malattie I | Metodo per la rivelazione di acidi nucleici virali o di origine virale nelle urine. |
AU2006224971B2 (en) | 2005-03-18 | 2009-07-02 | Boston University | A method for the detection of chromosomal aneuploidies |
EP1859051A4 (en) | 2005-03-18 | 2009-08-05 | Univ Hong Kong Chinese | MARKERS FOR PRENATAL DIAGNOSIS AND SURVEILLANCE |
AU2006226891A1 (en) | 2005-03-24 | 2006-09-28 | Beth Israel Deaconess Medical Center | Methods of diagnosing fetal trisomy 13 or a risk of fetal trisomy 13 during pregnancy |
DE602006014379D1 (de) | 2005-04-06 | 2010-07-01 | Klinik Und Poliklinik Fuer Psy | Neurodegenerative marker für depression. |
CN101198622A (zh) | 2005-04-18 | 2008-06-11 | 都柏林伊丽莎白女皇神学院 | Toll样受体14(TLR14)及其用途 |
WO2006114661A1 (en) | 2005-04-26 | 2006-11-02 | Dwek Raymond A | High throughput glycan analysis for diagnosing and monitoring rheumatoid arthritis and other autoimmune diseases |
US7604948B2 (en) | 2005-05-05 | 2009-10-20 | The Regents Of The University Of California | Biomarkers for diagnosing an autism spectrum disorder |
JP5421590B2 (ja) | 2005-05-18 | 2014-02-19 | ノバルティス アーゲー | 自己免疫および/または炎症性成分を有する疾患の診断および治療のための方法 |
WO2006135904A2 (en) * | 2005-06-13 | 2006-12-21 | Kohne David E | Method for producing improved results for applications which directly or indirectly utilize gene expression assay results |
GB0512401D0 (en) | 2005-06-17 | 2005-07-27 | Randox Lab Ltd | Method |
GB2428240A (en) | 2005-07-14 | 2007-01-24 | Univ Gen Ve | Diagnostic method for brain damage-related disorders |
US20070148661A1 (en) | 2005-07-19 | 2007-06-28 | Duke University | LSAMP Gene Associated With Cardiovascular Disease |
US20070218469A1 (en) | 2005-10-03 | 2007-09-20 | Ruth Navon | Novel mutations in hexosaminidase A |
IL172297A (en) | 2005-10-03 | 2016-03-31 | Compugen Ltd | Soluble vegfr-1 variants for the diagnosis of preeclampsia |
US20070218519A1 (en) | 2005-10-11 | 2007-09-20 | Tethys Bioscience, Inc. | Diabetes-associated markers and methods of use thereof |
US8652467B2 (en) | 2005-10-14 | 2014-02-18 | The Regents Of The University Of Michigan | Dek protein compositions and methods of using the same |
TW200736260A (en) | 2005-11-10 | 2007-10-01 | Smithkline Beecham Corp | Inhibitors of Akt activity |
KR101352222B1 (ko) | 2005-12-22 | 2014-02-04 | 백스터 인터내셔널 인코포레이티드 | 의료용 제품에서 비-내독소 발열성 오염물을 보다 잘검출할 수 있는 개선된 단핵구 활성화 시험 |
TW200726845A (en) | 2006-01-02 | 2007-07-16 | Nat Defense Medical Ct | Biomarker molecular of renal illness and detecting method for the same |
EP1808694A1 (en) | 2006-01-17 | 2007-07-18 | Universitätsklinikum Freiburg | Method for diagnosing polycystic kidney disease |
FR2896588B1 (fr) | 2006-01-20 | 2016-08-19 | Univ D'angers | Methode de diagnostic in vitro de reponse immunitaire autoimmune par detection d'anticorps diriges contre l'antigene pentraxine 3. |
WO2007090126A2 (en) | 2006-01-30 | 2007-08-09 | Invitrogen Corporation | Compositions and methods for detecting and quantifying toxic substances in disease states |
US7459280B2 (en) | 2006-02-27 | 2008-12-02 | Picobella, Llc | Methods for diagnosing and treating kidney cancer |
KR20080104350A (ko) | 2006-02-28 | 2008-12-02 | 페노미넘 디스커버리스 인코포레이티드 | 치매 및 다른 신경 장애의 진단을 위한 방법 |
US7488584B2 (en) | 2006-03-24 | 2009-02-10 | Picobella | Methods for diagnosing and treating kidney and colorectal cancer |
US20070224638A1 (en) | 2006-03-27 | 2007-09-27 | Institut Pasteur | Secreted proteins as early markers and drug targets for autoimmunity, tumorigenesis and infections |
GB0606776D0 (en) | 2006-04-03 | 2006-05-10 | Novartis Pharma Ag | Predictive biomarkers for chronic allograft nephropathy |
EP1847615A1 (en) | 2006-04-18 | 2007-10-24 | Genoscreen | Expression and polymorphism of the ornithine transcarbamylase (OTC) gene as markers for diagnosing Alzheimer's disease |
US7662578B2 (en) | 2006-04-21 | 2010-02-16 | Children's Hospital Medical Center | Method and kit for the early detection of impaired renal status |
ATE517341T1 (de) | 2006-04-27 | 2011-08-15 | Critical Care Diagnostics Inc | Interleukin-33 (il-33) zur diagnose und vorhersage von herz-gefäss-erkrankungen |
EP3059594A1 (en) | 2006-05-01 | 2016-08-24 | Critical Care Diagnostics, Inc. | Prognosis of cardiovascular disease |
US7754428B2 (en) | 2006-05-03 | 2010-07-13 | The Chinese University Of Hong Kong | Fetal methylation markers |
US7901884B2 (en) | 2006-05-03 | 2011-03-08 | The Chinese University Of Hong Kong | Markers for prenatal diagnosis and monitoring |
WO2007131345A1 (en) | 2006-05-12 | 2007-11-22 | The Hospital For Sick Children | Genetic risk factor in sod1 and sfrs15 in renal disease, diabetic cataract, cardiovascular disease and longevity |
EP2020445B1 (en) | 2006-05-12 | 2013-01-02 | Keio University | Detection of inflammatory disease and composition for prevention or treatment of inflammatory disease |
EP2548578B1 (en) | 2006-05-17 | 2014-08-20 | The Ludwig Institute for Cancer Research | Targeting VEGF-B regulation of fatty acid transporters to modulate human diseases |
WO2007139895A2 (en) | 2006-05-24 | 2007-12-06 | Cellumen, Inc. | Method for modeling a disease |
US20080038269A1 (en) | 2006-05-25 | 2008-02-14 | Mount Sinai Hospital | Methods for detecting and treating kidney disease |
EP2924440A3 (en) | 2006-06-07 | 2016-03-09 | Health Diagnostic Laboratory, Inc. | Markers associated with arteriovascular events and methods of use thereof |
DE102006027818A1 (de) | 2006-06-16 | 2007-12-20 | B.R.A.H.M.S. Aktiengesellschaft | In vitro Multiparameter-Bestimmungsverfahren zur Diagnose und Frühdiagnose von neurodegenerativen Erkrankungen |
WO2008084331A2 (en) | 2006-06-21 | 2008-07-17 | Hopitaux Universitaires De Geneve | Biomarkers for renal disorders |
WO2008003826A1 (en) | 2006-07-07 | 2008-01-10 | Oy Jurilab Ltd | Novel genes and markers in essential arterial hypertension |
KR100856375B1 (ko) | 2006-07-18 | 2008-09-04 | 김현기 | 퇴행성 신경질환 진단용 마커 |
US7851172B2 (en) | 2006-07-25 | 2010-12-14 | University Of Kentucky Research Foundation | Biomarkers of mild cognitive impairment and alzheimer's disease |
US20080026378A1 (en) | 2006-07-28 | 2008-01-31 | Gian Franco Bottazzo | Prediction and prophylactic treatment of type 1 diabetes |
US20080113358A1 (en) | 2006-07-28 | 2008-05-15 | Ravi Kapur | Selection of cells using biomarkers |
ITTO20060614A1 (it) | 2006-08-21 | 2008-02-22 | Uni Degli Studi Del Piemonte | "diagnosi differenziale per la sclerodermia" |
WO2008028257A1 (en) | 2006-09-08 | 2008-03-13 | Garvan Institute Of Medical Research | Diagnostics and therapeutics of neurological disease |
US20090318392A1 (en) | 2006-09-14 | 2009-12-24 | Zora Biosciences Oy | Biofluid metabolite profiling as a tool for early prediction of autoimmunity and type 1 diabetes risk |
EP1905841A1 (en) | 2006-09-25 | 2008-04-02 | Max Delbrück Centrum für Molekulare Medizin (MDC) Berlin-Buch; | Trex1 as a marker for lupus erythematosus |
US20090318354A1 (en) | 2006-09-26 | 2009-12-24 | Proteosys Ag | Use of at least one isoform of progesterone receptor membrane component 1 (PGRMC1) |
CA2665365A1 (en) | 2006-10-05 | 2008-04-10 | Rhode Island Hospital | Compositions and methods for detecting and treating renal injury and inflammation |
WO2008043725A1 (en) | 2006-10-10 | 2008-04-17 | Novartis Ag | Biomarker in inflammatory disorders |
EP2081649A2 (en) | 2006-10-11 | 2009-07-29 | Novartis AG | Modulation of cd1b or cd1d expression in autoimmune disorders |
WO2008046510A1 (en) | 2006-10-16 | 2008-04-24 | Bayer Healthcare Ag | Fn1 as a biomarker, therapeutic and diagnostic target |
EP2087359A1 (en) | 2006-10-16 | 2009-08-12 | Bayer Schering Pharma AG | Prss23 as a biomarker, therapeutic and diagnostic target |
US8088584B2 (en) | 2006-10-16 | 2012-01-03 | Bayer Schering Pharma Aktiengesellschaft | LTBP2 as a biomarker and diagnostic target |
WO2008046511A1 (en) | 2006-10-16 | 2008-04-24 | Bayer Schering Pharma Aktiengesellschaft | Crtac as a biomarker, therapeutic and diagnostic target |
WO2008046160A1 (en) | 2006-10-20 | 2008-04-24 | Newcastle Innovation Limited | Assay for the detection of biomarkers associated with pregnancy related conditions |
EP2097094A4 (en) | 2006-11-01 | 2011-01-05 | George Mason Intellectual Prop | BIOMARKERS FOR NEUROLOGICAL SUFFERING |
WO2008064336A2 (en) | 2006-11-22 | 2008-05-29 | Inivitrogen Corporation | Autoimmune disease biomarkers |
US20100169988A1 (en) | 2006-12-06 | 2010-07-01 | Bernhard Kohli | Means and methods for isolating and determining novel targets for the treatment of neurodegenerative, neurological or neuropsychiatric disorders and compositions comprising the same |
US20090104605A1 (en) | 2006-12-14 | 2009-04-23 | Gary Siuzdak | Diagnosis of sepsis |
IL180095A0 (en) | 2006-12-14 | 2007-05-15 | Ohad Birk | Method for antenatal estimation of down syndrome risk |
US8362224B2 (en) | 2006-12-19 | 2013-01-29 | The Trustees Of The University Of Pennsylvania | Screening for CD93 (C1qRp)-associated polymorphism(S) in the diagnosis, prevention and treatment of autoimmune diseases |
US8815519B2 (en) | 2006-12-22 | 2014-08-26 | Hvidovre Hospital | Method for predicting cancer and other diseases |
EP2155228B1 (en) | 2007-01-10 | 2014-04-02 | Purdue Research Foundation | Polypeptide inhibitors of hsp27 kinase and uses therefor |
WO2008085024A1 (en) | 2007-01-12 | 2008-07-17 | Erasmus University Medical Center Rotterdam | Identification and detection of peptides relating to specific disorders |
EP2115168A1 (en) | 2007-01-22 | 2009-11-11 | Medizinische Universität Innsbruck | Novel markers for chronic kidney disease |
AU2008213742A1 (en) | 2007-02-08 | 2008-08-14 | Powmri Limited | Method of diagnosing a neurodegenerative disease |
WO2008100596A2 (en) | 2007-02-15 | 2008-08-21 | Burnham Institute For Medical Research | Biomarkers of neurodegenerative disease |
CA2679581C (en) | 2007-02-21 | 2020-12-22 | Anna Helgadottir | Genetic susceptibility variants associated with arterial disease |
WO2008112772A2 (en) | 2007-03-14 | 2008-09-18 | Baylor Research Institute | Gene expression in peripheral blood mononuclear cells from children with diabetes |
WO2008118813A2 (en) | 2007-03-26 | 2008-10-02 | The Government Of The U.S.A, As Represented By The Secretary, Dept. Of Health And Human Services | Schizophrenia-related isoform of kcnh2 and development of antipsychotic drugs |
EP1975252A1 (en) | 2007-03-29 | 2008-10-01 | INSERM (Institut National de la Santé et de la Recherche Medicale) | Methods for the prognosis or for the diagnosis of a thyroid disease |
JP5555846B2 (ja) | 2007-03-30 | 2014-07-23 | 国立大学法人山口大学 | 急性中枢神経障害の予後判定方法 |
CA2683865A1 (en) | 2007-04-12 | 2008-10-23 | Apitope International Nv | Biomarkers for multiple sclerosis |
GB0707933D0 (en) | 2007-04-24 | 2007-05-30 | Apitope Technology Bristol Ltd | Disease markers |
GB0708075D0 (en) | 2007-04-26 | 2007-06-06 | Univ Nottingham | Nethods |
EP2162459B1 (en) | 2007-05-01 | 2017-10-04 | University of Miami | Transcriptomic biomarkers for individual risk assessment in new onset heart failure |
CA2686861A1 (en) | 2007-05-03 | 2008-11-13 | Medimmune, Llc | Interferon alpha-induced pharmacodynamic markers |
WO2008147938A2 (en) | 2007-05-24 | 2008-12-04 | Centocor, Inc. | Wnt5a as an inflammatory disease marker |
WO2008154238A1 (en) | 2007-06-06 | 2008-12-18 | Siemens Healthcare Diagnostics Inc. | Predictive diagnostics for kidney disease |
CA2689131A1 (en) | 2007-06-08 | 2008-12-11 | Vib Vzw | The novel adipocytokine visfatin/pbef1 is an apoptosis associated factor induced in monocytes during in vivo hiv-1 infection |
US20090142792A1 (en) | 2007-06-21 | 2009-06-04 | Robinson William H | Biomarkers for the diagnosis of autoimmune disease |
ITRM20070351A1 (it) | 2007-06-22 | 2008-12-23 | Istituto Naz Per Le Malattie I | Gene codificante la proteina ambra 1 avente attivita' regolatoria dell autofagia e dello sviluppo del sistema nervoso centrale |
WO2009000520A1 (en) | 2007-06-25 | 2008-12-31 | Universität Duisburg-Essen | Screening-method for polymorphic markers in htra1 gene in neurodegenerative disorders |
EP2167961A4 (en) | 2007-06-27 | 2010-07-21 | Univ Leland Stanford Junior | BETA2-MICROGLOBULIN AND C-REACTIVE PROTEIN (CRP) AS BIOMARKERS FOR PERIPHERAL ARTERY DISEASE |
JP2010533866A (ja) | 2007-07-13 | 2010-10-28 | ジェネンテック, インコーポレイテッド | 癌、炎症性疾患及び自己免疫疾患の治療及び診断方法 |
ES2443540T3 (es) | 2007-07-17 | 2014-02-19 | Metabolon, Inc. | Biomarcadores para pre-diabetes y métodos que usan los mismos |
EP2185936A4 (en) | 2007-08-02 | 2010-08-04 | Iss Immune System Stimulation | DIAGNOSIS, STADIFICATION AND SURVEILLANCE OF INFLAMMATORY ABDOMINAL DISEASE |
WO2009032722A1 (en) | 2007-08-29 | 2009-03-12 | The Cleveland Clinic Foundation | Carbamylated proteins and risk of cardiovascular disease |
US20090275046A1 (en) | 2007-08-29 | 2009-11-05 | Power3 Medical Products, Inc. | Complement factor H protein as a biomarker of Parkinson's disease |
US8748100B2 (en) | 2007-08-30 | 2014-06-10 | The Chinese University Of Hong Kong | Methods and kits for selectively amplifying, detecting or quantifying target DNA with specific end sequences |
GB0717637D0 (en) | 2007-09-10 | 2007-10-17 | Univ Leiden | Future cardiac event biomarkers |
US8062852B2 (en) | 2007-10-01 | 2011-11-22 | The Children's Hospital And Regional Medical Center | Detection and treatment of autoimmune disorders |
ITUD20070183A1 (it) | 2007-10-01 | 2009-04-02 | Univ Degli Studi Udine | Metodo diagnostico e prognostico per la diagnosi e la prognosi della linfoproliferazione nelle malattie autoimmuni |
WO2009050446A1 (en) | 2007-10-15 | 2009-04-23 | King's College London | Viral therapeutic |
EP2212693B1 (en) | 2007-10-22 | 2015-04-22 | The Regents of The University of California | Biomarkers for prenatal diagnosis of congenital cytomegalovirus |
FI20070795A0 (fi) | 2007-10-24 | 2007-10-24 | Faron Pharmaceuticals Oy | Uusi biomarkkeri sairauksien kehittämisen tarkkailuun ja terapioiden tehon arviointiin |
EP2557425A3 (en) | 2007-10-26 | 2013-07-10 | Biohit Oyj | Methods and products for diagnosing autoimmune diseases and gastric cancer linked with atrophic gastritis |
WO2009059259A2 (en) | 2007-10-31 | 2009-05-07 | Children's Hospital Medical Center | Detection of worsening renal disease in subjects with systemic lupus erythematosus |
WO2009058168A1 (en) | 2007-11-04 | 2009-05-07 | Prediction Sciences Llc | Cellular fibronectin as a diagnostic marker in cardiovascular disease and methods of use thereof |
US20100233716A1 (en) | 2007-11-08 | 2010-09-16 | Pierre Saint-Mezard | Transplant rejection markers |
WO2009065132A1 (en) | 2007-11-16 | 2009-05-22 | Oklahoma Medical Research Foundation | Predicting and diagnosing patients with autoimmune disease |
US20100255485A1 (en) | 2007-11-28 | 2010-10-07 | Pico Caroni | Biomarkers for the onset of neurodegenerative diseases |
US8506933B2 (en) | 2007-11-30 | 2013-08-13 | Msdx, Inc. | Methods of detecting a neurological condition via analysis of circulating phagocytes |
WO2009074331A2 (en) | 2007-12-11 | 2009-06-18 | Julius-Maximilians-Universität Würzburg | Early and differential diagnosis test for alzheimer's disease |
WO2009075566A1 (en) | 2007-12-12 | 2009-06-18 | Erasmus University Medical Center Rotterdam | Biomarkers for cardiovascular disease |
EP2075343A1 (en) | 2007-12-21 | 2009-07-01 | Gert Mayer | A method of diagnosing a progressive disease |
EP2240601B1 (en) | 2007-12-27 | 2016-10-12 | Compugen Ltd. | Biomarkers for the prediction of renal injury |
SG10201704689XA (en) | 2008-01-18 | 2017-07-28 | Harvard College | Methods of detecting signatures of disease or conditions in bodily fluids |
CA2739944A1 (en) | 2008-01-23 | 2009-07-30 | Rigshospitalet | Classification of individuals suffering from cardiovascular diseases according to survival prognoses as found by measuring the levels of biomarker ykl-40 |
WO2009097450A1 (en) | 2008-01-30 | 2009-08-06 | Dexcom. Inc. | Continuous cardiac marker sensor system |
EP3115785A3 (en) | 2008-02-04 | 2017-02-22 | Banyan Biomarkers, Inc. | Process to diagnose or treat brain injury |
AU2009212216B2 (en) | 2008-02-08 | 2015-04-09 | Brigham And Women's Hospital, Inc. | Disease markers and uses thereof |
US20090239242A1 (en) | 2008-03-18 | 2009-09-24 | Biotrin Intellectual Properties Limited | Method for the early identification and prediction of kidney injury |
AU2008255192A1 (en) | 2008-03-22 | 2009-10-08 | Newcastle Innovation Limited | Detection of a biomarker of aberrant cells of neuroectodermal origin in a body fluid |
GB0809069D0 (en) | 2008-05-19 | 2008-06-25 | Univ Leuven Kath | Gene signatures |
EP2107377A1 (en) | 2008-04-04 | 2009-10-07 | BRAHMS Aktiengesellschaft | Pro-endothelin-1 levels for the prediction of risk of tachyarrhytmic events |
WO2009122387A1 (en) | 2008-04-04 | 2009-10-08 | Biotrin Group Ltd. | Method for the detection and prediction of obesity-related renal disease |
AU2009237710A1 (en) | 2008-04-15 | 2009-10-22 | Rainer Oberbauer | Markers of acute kidney failure |
US8030097B2 (en) | 2008-04-30 | 2011-10-04 | Versitech Limited and R & C Biogenius Limited | Lipocalin-2 as a prognostic and diagnostic marker for heart and stroke risks |
WO2010005750A2 (en) | 2008-06-16 | 2010-01-14 | The Regents Of The University Of California | Potential prognostic markers and therapeutic targets for neurological disorders |
US20100167937A1 (en) | 2008-07-08 | 2010-07-01 | Power3 Medical Products, Inc. | Multiple forms of Alzheimer's disease based on differences in concentrations of protein biomarkers in blood serum |
US20100068711A1 (en) | 2008-07-18 | 2010-03-18 | Xenomics, Inc. | Methods of PCR-Based Detection of "Ultra Short" Nucleic Acid Sequences |
US20110177509A1 (en) | 2008-07-23 | 2011-07-21 | The Washington University | Risk factors and a therapeutic target for neurodegenerative disorders |
JP2011529453A (ja) | 2008-07-31 | 2011-12-08 | ホスピタル クリニク アイ プロビンシアル デ バルセロナ | 健康な腎臓のバイオマーカ |
EP4235181A3 (en) | 2008-08-11 | 2024-02-28 | Banyan Biomarkers Inc | Biomarker detection process and assay of neurological condition |
ES2341419B1 (es) | 2008-08-14 | 2011-05-03 | Hospital Clinic I Provincial De Barcelona | Wnt1 como biomarcador de daño renal. |
WO2010022210A2 (en) | 2008-08-21 | 2010-02-25 | Pxbiosciences Llc | Diagnosis and monitoring of renal failure using peptide biomarkers |
WO2010025434A1 (en) | 2008-08-29 | 2010-03-04 | Astute Medical, Inc. | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
EP2161577A1 (en) | 2008-09-01 | 2010-03-10 | Atlas Antibodies AB | ANLN protein |
CA2737379A1 (en) | 2008-09-30 | 2010-04-08 | Genentech, Inc. | Biological markers predictive of rheumatoid arthritis response to lymphotoxin antagonists |
US20100124756A1 (en) | 2008-10-10 | 2010-05-20 | Sandip Ray | Collection of biomarkers for diagnosis and monitoring of alzheimer's disease in body fluids |
GB0818650D0 (en) | 2008-10-10 | 2008-11-19 | Uni I Oslo | Methods |
WO2010048347A2 (en) | 2008-10-21 | 2010-04-29 | Astute Medical, Inc. | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
NZ628843A (en) | 2008-10-21 | 2016-02-26 | Astute Medical Inc | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
EP2180322A1 (en) | 2008-10-22 | 2010-04-28 | BRAHMS Aktiengesellschaft | Prognostic biomarkers for the progression of primary chronic kidney disease |
KR101051435B1 (ko) | 2008-10-22 | 2011-07-22 | 한국생명공학연구원 | 대장암 관련 마커를 이용한 대장암 진단 키트 및 이를 이용한 대장암 진단 방법 |
WO2010046503A2 (en) | 2008-10-24 | 2010-04-29 | Vereniging Vu-Windesheim | Biomarkers for predicting the development of chronic autoimmune diseases |
WO2010048497A1 (en) | 2008-10-24 | 2010-04-29 | Genizon Biosciences Inc. | Genetic profile of the markers associated with alzheimer's disease |
US20110236397A1 (en) | 2008-11-06 | 2011-09-29 | University Of Miami | Limited proteolysis of cd2ap and progression of renal disease |
EP2719774B8 (en) | 2008-11-07 | 2020-04-22 | Adaptive Biotechnologies Corporation | Methods of monitoring conditions by sequence analysis |
BRPI0922021A2 (pt) | 2008-11-10 | 2019-09-24 | Astute Medical Inc | método para avaliar a condição renal em um indivíduo, e, uso de um ou mais marcadores de lesão renal |
WO2010056757A1 (en) | 2008-11-11 | 2010-05-20 | Entelos, Inc. | Biomarkers for assessing atherosclerotic potential |
US20120094295A1 (en) | 2008-11-21 | 2012-04-19 | The Johns Hopkins University | Neurodegenerative disease diagnostic compositions and methods of use |
ES2528799T3 (es) | 2008-11-22 | 2015-02-12 | Astute Medical, Inc. | Métodos para el pronóstico de insuficiencia renal aguda |
IT1392551B1 (it) | 2008-11-25 | 2012-03-09 | Bioindustry Park Del Canavese S P A | Biomarcatori per la diagnosi e per rilevare la progressione di malattie neurodegenerative, in particolare della sclerosi laterale amiotrofica |
AU2009326857B2 (en) | 2008-12-09 | 2016-05-26 | Stephanie Fryar-Williams | Novel biomarkers |
EP3474016A1 (en) | 2008-12-10 | 2019-04-24 | Joslin Diabetes Center, Inc. | Methods of diagnosing and predicting renal disease |
CA2806301A1 (en) | 2010-07-23 | 2012-01-26 | President And Fellows Of Harvard College | Methods of detecting cardiovascular diseases or conditions |
AU2011280997A1 (en) | 2010-07-23 | 2013-02-28 | President And Fellows Of Harvard College | Methods of detecting autoimmune or immune-related diseases or conditions |
WO2012012714A2 (en) | 2010-07-23 | 2012-01-26 | President And Fellows Of Harvard College | Methods of detecting neurological or neuropsychiatric diseases or conditions |
JP2013541323A (ja) | 2010-07-23 | 2013-11-14 | プレジデント アンド フェロウズ オブ ハーバード カレッジ | 貪食細胞を用いて疾患または症状のシグネチャを検出する方法 |
MX361944B (es) | 2010-07-23 | 2018-12-19 | President And Fellows Of Harvard College Star | Metodos para detectar firmas de enfermedad o condiciones en fluidos corporales. |
US20130203624A1 (en) | 2010-07-23 | 2013-08-08 | President And Fellows Of Harvard College | Methods of Detecting Prenatal or Pregnancy-Related Diseases or Conditions |
WO2012012704A2 (en) | 2010-07-23 | 2012-01-26 | President And Fellows Of Harvard College | Methods of detecting kidney-associated diseases or conditions |
WO2012115885A1 (en) | 2011-02-22 | 2012-08-30 | Caris Life Sciences Luxembourg Holdings, S.A.R.L. | Circulating biomarkers |
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Patent Citations (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4814434A (en) * | 1984-02-03 | 1989-03-21 | Ventres Laboratories, Inc. | Inducer of T-suppressor cells |
US5043267A (en) * | 1984-05-18 | 1991-08-27 | E. I. Du Pont De Nemours And Company | Method for rapid detection of bacterial and fungal infection |
US20010051344A1 (en) * | 1994-06-17 | 2001-12-13 | Shalon Tidhar Dari | Methods for constructing subarrays and uses thereof |
US6117985A (en) * | 1995-06-16 | 2000-09-12 | Stemcell Technologies Inc. | Antibody compositions for preparing enriched cell preparations |
US20060088836A1 (en) * | 2002-04-24 | 2006-04-27 | Jay Wohlgemuth | Methods and compositions for diagnosing and monitoring transplant rejection |
US20060094067A1 (en) * | 2002-06-26 | 2006-05-04 | Ralf Herwig | Method for the determination of characteristics and/or the classification of circulating macrophages, and analysis arrangement for carrying out said method |
US20060115832A1 (en) * | 2002-11-14 | 2006-06-01 | Jon Wayne Cancer Institute | Detection of cancer cells in body fluids |
US20070015172A1 (en) * | 2005-06-01 | 2007-01-18 | Z-Biomed, Inc. | Expression profiles for microbial infection |
US20070099209A1 (en) * | 2005-06-13 | 2007-05-03 | The Regents Of The University Of Michigan | Compositions and methods for treating and diagnosing cancer |
US20070134689A1 (en) * | 2005-09-28 | 2007-06-14 | National Taiwan University | Tumor marker for ovarian cancer diagnosis |
Non-Patent Citations (6)
Title |
---|
Herwig et al. Clinical Prostate Cancer, Vol. 3, No. 3, 184-188, 2004 * |
Lee (Clinical Chemistry, 47:8, 1350-1352 (2001) * |
Michiels et al. Lancet, 2005; 365:488-492 * |
Palmer et al. BMC Genomics 2006, 7:115, fifteen pages. * |
Slonin, Nature Genetics Supplement, Vol. 32, December 2002, pages 502-508 * |
Thisted (1998) What is a P-Value. University of Chicago. 25 May 1998. accessed from http://www.stat.uchicago.edu/~thisted. six pages. * |
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