US20100144684A1 - Method of Safely and Effectively Treating and Preventing Secondary Hyperparathyroidism in Chronic Kidney Disease - Google Patents
Method of Safely and Effectively Treating and Preventing Secondary Hyperparathyroidism in Chronic Kidney Disease Download PDFInfo
- Publication number
- US20100144684A1 US20100144684A1 US12/597,234 US59723408A US2010144684A1 US 20100144684 A1 US20100144684 A1 US 20100144684A1 US 59723408 A US59723408 A US 59723408A US 2010144684 A1 US2010144684 A1 US 2010144684A1
- Authority
- US
- United States
- Prior art keywords
- hydroxyvitamin
- patient
- vitamin
- administering
- dihydroxyvitamin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
- A61K31/593—9,10-Secocholestane derivatives, e.g. cholecalciferol, i.e. vitamin D3
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
- A61K31/592—9,10-Secoergostane derivatives, e.g. ergocalciferol, i.e. vitamin D2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/14—Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4
- A61P5/16—Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4 for decreasing, blocking or antagonising the activity of the thyroid hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/18—Drugs for disorders of the endocrine system of the parathyroid hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/18—Drugs for disorders of the endocrine system of the parathyroid hormones
- A61P5/20—Drugs for disorders of the endocrine system of the parathyroid hormones for decreasing, blocking or antagonising the activity of PTH
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Nutrition Science (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US12/597,234 US20100144684A1 (en) | 2007-04-25 | 2008-04-25 | Method of Safely and Effectively Treating and Preventing Secondary Hyperparathyroidism in Chronic Kidney Disease |
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US91385007P | 2007-04-25 | 2007-04-25 | |
US12/597,234 US20100144684A1 (en) | 2007-04-25 | 2008-04-25 | Method of Safely and Effectively Treating and Preventing Secondary Hyperparathyroidism in Chronic Kidney Disease |
PCT/US2008/061594 WO2008134523A1 (en) | 2007-04-25 | 2008-04-25 | Method of safely and effectively treating and preventing secondary hyperparathyroidism in chronic kidney disease |
Related Parent Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2008/061594 A-371-Of-International WO2008134523A1 (en) | 2007-04-25 | 2008-04-25 | Method of safely and effectively treating and preventing secondary hyperparathyroidism in chronic kidney disease |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US14/291,666 Continuation US20140274977A1 (en) | 2007-04-25 | 2014-05-30 | Method of safely and effectively treating and preventing secondary hyperparathyroidism in chronic kidney disease |
Publications (1)
Publication Number | Publication Date |
---|---|
US20100144684A1 true US20100144684A1 (en) | 2010-06-10 |
Family
ID=39926088
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US12/597,234 Abandoned US20100144684A1 (en) | 2007-04-25 | 2008-04-25 | Method of Safely and Effectively Treating and Preventing Secondary Hyperparathyroidism in Chronic Kidney Disease |
US14/291,666 Abandoned US20140274977A1 (en) | 2007-04-25 | 2014-05-30 | Method of safely and effectively treating and preventing secondary hyperparathyroidism in chronic kidney disease |
US15/720,830 Active 2030-09-07 US11801253B2 (en) | 2007-04-25 | 2017-09-29 | Method of safely and effectively treating and preventing secondary hyperparathyroidism in chronic kidney disease |
Family Applications After (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US14/291,666 Abandoned US20140274977A1 (en) | 2007-04-25 | 2014-05-30 | Method of safely and effectively treating and preventing secondary hyperparathyroidism in chronic kidney disease |
US15/720,830 Active 2030-09-07 US11801253B2 (en) | 2007-04-25 | 2017-09-29 | Method of safely and effectively treating and preventing secondary hyperparathyroidism in chronic kidney disease |
Country Status (5)
Country | Link |
---|---|
US (3) | US20100144684A1 (ja) |
EP (3) | EP3225243A1 (ja) |
JP (5) | JP2010525080A (ja) |
CA (1) | CA2683514C (ja) |
WO (1) | WO2008134523A1 (ja) |
Cited By (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20080261925A1 (en) * | 2006-12-29 | 2008-10-23 | Margaret Clagett-Dame | Compounds, compositions, kits and methods of use to orally and topically treat acne and other skin conditions by administering a 19-nor containing vitamin d analog with or without a retinoid |
US20120157418A1 (en) * | 2009-10-02 | 2012-06-21 | Wisconsin Alumni Research Foundation | 2-Methylene-19-Nor-Vitamin D Analogs and Their Uses |
US9408858B2 (en) | 2007-04-25 | 2016-08-09 | Opko Renal, Llc | Method for treating secondary hyperparathyroidism in CKD |
US9943530B2 (en) | 2006-02-03 | 2018-04-17 | Opko Renal, Llc | Treating vitamin D insufficiency and deficiency with 25-hydroxyvitamin D2 and 25-hydroxyvitamin D3 |
US10220047B2 (en) | 2014-08-07 | 2019-03-05 | Opko Ireland Global Holdings, Ltd. | Adjunctive therapy with 25-hydroxyvitamin D and articles therefor |
US10302660B2 (en) | 2008-04-02 | 2019-05-28 | Opko Renal, Llc | Methods useful for vitamin D deficiency and related disorders |
US10300078B2 (en) | 2013-03-15 | 2019-05-28 | Opko Ireland Global Holdings, Ltd. | Stabilized modified release vitamin D formulation and method of administering same |
WO2019193425A1 (en) | 2018-04-03 | 2019-10-10 | Opko Ireland Global Holdings, Ltd. | Use of calcifediol in bariatric surgery patients |
US10668089B2 (en) | 2006-06-21 | 2020-06-02 | Opko Ireland Global Holdings, Ltd. | Method of treating and preventing secondary hyperparathyroidism |
WO2020161543A1 (en) | 2019-02-06 | 2020-08-13 | Opko Ireland Global Holdings, Limited | Method of controlling progression of hyperparathyroidism with calcifediol, and compositions for use therein |
US11026625B2 (en) | 2017-08-08 | 2021-06-08 | Fresenius Medical Care Holdings, Inc. | Systems and methods for treating and estimating progression of chronic kidney disease |
US11173168B2 (en) | 2016-03-28 | 2021-11-16 | Eirgen Pharma Ltd. | Methods of treating vitamin D insufficiency in chronic kidney disease |
US11672809B2 (en) | 2010-03-29 | 2023-06-13 | Eirgen Pharma Ltd. | Methods and compositions for reducing parathyroid levels |
US11752158B2 (en) | 2007-04-25 | 2023-09-12 | Eirgen Pharma Ltd. | Method of treating vitamin D insufficiency and deficiency |
US11801253B2 (en) | 2007-04-25 | 2023-10-31 | Opko Renal, Llc | Method of safely and effectively treating and preventing secondary hyperparathyroidism in chronic kidney disease |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2008134518A2 (en) | 2007-04-25 | 2008-11-06 | Cytochroma Inc. | Methods and compounds for vitamin d therapy |
WO2009101132A1 (en) * | 2008-02-13 | 2009-08-20 | Dsm Ip Assets B.V. | Combination of vitamin d and 25-hydroxyvitamin d 3 |
AU2010281391B2 (en) * | 2009-08-03 | 2015-05-07 | Wisconsin Alumni Research Foundation | Method of preventing renal disease and treating symptoms thereof |
TR201902517T4 (tr) * | 2010-12-06 | 2019-03-21 | Dsm Ip Assets Bv | 25-hidroksivitamin D3 ile artan eotaksin ile ilişkilendirilen durumların tedavi edilmesi. |
US9539264B2 (en) * | 2014-12-30 | 2017-01-10 | Wisconsin Alumni Research Foundation | Use of 2-methylene-19-nor-(20S)-1-alpha,25-dihydroxyvitamin D3 to treat secondary hyperparathyroidism in patients previously treated with calcimimetics |
WO2017117712A1 (zh) * | 2016-01-05 | 2017-07-13 | 富士通株式会社 | 信息传输方法、装置和系统 |
JP7106563B2 (ja) | 2016-11-29 | 2022-07-26 | スミトモ ファーマ オンコロジー, インコーポレイテッド | ナフトフラン誘導体、その調製、および使用方法 |
KR20230017192A (ko) * | 2020-05-31 | 2023-02-03 | 에어젠 파마 엘티디. | 경질 캡슐 투여 형태 및 이의 용도 |
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US20090176748A1 (en) * | 2007-04-25 | 2009-07-09 | Cytochroma Inc. | Methods and compositions for controlled release oral dosage of a vitamin d compound |
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Also Published As
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US20140274977A1 (en) | 2014-09-18 |
EP3225243A1 (en) | 2017-10-04 |
EP3335712A1 (en) | 2018-06-20 |
JP2014098034A (ja) | 2014-05-29 |
US11801253B2 (en) | 2023-10-31 |
US20180021355A1 (en) | 2018-01-25 |
JP2017075183A (ja) | 2017-04-20 |
EP2148683A4 (en) | 2012-09-12 |
WO2008134523A1 (en) | 2008-11-06 |
CA2683514A1 (en) | 2008-11-06 |
JP2010525080A (ja) | 2010-07-22 |
EP2148683A1 (en) | 2010-02-03 |
JP2019196402A (ja) | 2019-11-14 |
CA2683514C (en) | 2019-07-09 |
JP2018009040A (ja) | 2018-01-18 |
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