SI2341899T1 - Od pH odvisen opioidni farmacevtski sestavek z nadzorovanim sproščanjem z odpornostjo na vpliv etanola - Google Patents
Od pH odvisen opioidni farmacevtski sestavek z nadzorovanim sproščanjem z odpornostjo na vpliv etanolaInfo
- Publication number
- SI2341899T1 SI2341899T1 SI200831386T SI200831386T SI2341899T1 SI 2341899 T1 SI2341899 T1 SI 2341899T1 SI 200831386 T SI200831386 T SI 200831386T SI 200831386 T SI200831386 T SI 200831386T SI 2341899 T1 SI2341899 T1 SI 2341899T1
- Authority
- SI
- Slovenia
- Prior art keywords
- ethanol
- influence
- controlled release
- resistance against
- release pharmaceutical
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
- A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/485—Morphinan derivatives, e.g. morphine, codeine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/32—Alcohol-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/36—Opioid-abuse
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP08804667.7A EP2341899B1 (en) | 2008-09-24 | 2008-09-24 | Ph-dependent controlled release pharmaceutical opioid composition with resistance against the influence of ethanol |
| PCT/EP2008/062761 WO2010034342A1 (en) | 2008-09-24 | 2008-09-24 | Ph-dependent controlled release pharmaceutical opioid composition with resistance against the influence of ethanol |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SI2341899T1 true SI2341899T1 (sl) | 2015-04-30 |
Family
ID=40691361
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SI200831386T SI2341899T1 (sl) | 2008-09-24 | 2008-09-24 | Od pH odvisen opioidni farmacevtski sestavek z nadzorovanim sproščanjem z odpornostjo na vpliv etanola |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US9757343B2 (sl) |
| EP (1) | EP2341899B1 (sl) |
| JP (1) | JP5453433B2 (sl) |
| KR (1) | KR101528957B1 (sl) |
| CN (1) | CN102164588B (sl) |
| BR (1) | BRPI0823096B8 (sl) |
| CA (1) | CA2738078C (sl) |
| ES (1) | ES2532877T3 (sl) |
| IL (1) | IL211306A (sl) |
| MX (1) | MX2011003047A (sl) |
| PL (1) | PL2341899T3 (sl) |
| SI (1) | SI2341899T1 (sl) |
| WO (1) | WO2010034342A1 (sl) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2882048C (en) | 2006-02-03 | 2020-03-24 | Proventiv Therapeutics, Llc | Treating vitamin d insufficiency and deficiency with 25-hydroxyvitamin d2 and 25-hydroxyvitamin d3 |
| ES2497494T3 (es) | 2006-06-21 | 2014-09-23 | Opko Renal, Llc | Método de tratamiento y prevención del hiperparatiroidismo secundario |
| WO2009047644A2 (en) | 2007-04-25 | 2009-04-16 | Cytochroma Inc. | Method of treating vitamin d insufficiency and deficiency |
| KR20190028822A (ko) | 2007-04-25 | 2019-03-19 | 사이토크로마 인코포레이티드 | 비타민 ｄ 화합물과 밀랍성 담체를 포함하는 경구 조절성 방출 조성물 |
| WO2008134523A1 (en) | 2007-04-25 | 2008-11-06 | Proventiv Therapeutics, Llc | Method of safely and effectively treating and preventing secondary hyperparathyroidism in chronic kidney disease |
| US8962239B2 (en) | 2008-04-02 | 2015-02-24 | Opko Renal, Llc | Methods useful for vitamin D deficiency and related disorders |
| PL2408436T3 (pl) | 2009-03-18 | 2017-08-31 | Evonik Röhm Gmbh | Kompozycja farmaceutyczna o kontrolowanym uwalnianiu z odpornością na wpływ etanolu, wykorzystująca powłokę zawierającą neutralne polimery winylowe i zaróbki |
| PT2552484T (pt) | 2010-03-29 | 2020-04-03 | Opko Ireland Global Holdings Ltd | Métodos e composições para redução dos níveis de parafróides |
| CN103002881B (zh) | 2010-05-10 | 2015-09-02 | 欧洲凯尔特公司 | 载有活性剂的颗粒与额外活性剂的组合 |
| AU2011252040C1 (en) | 2010-05-10 | 2015-04-02 | Euro-Celtique S.A. | Manufacturing of active-free granules and tablets comprising the same |
| CH705273B1 (de) | 2010-05-10 | 2016-06-15 | Euro Celtique Sa | Pharmazeutische Zusammensetzung – umfassend Hydromorphon und Naloxon. |
| PL2720682T3 (pl) | 2011-06-17 | 2017-05-31 | Evonik Röhm Gmbh | Kompozycja powlekająca odpowiednia do farmaceutycznych lub nutraceutycznych postaci dawkowania |
| KR101799625B1 (ko) | 2011-06-17 | 2017-11-20 | 에보니크 룀 게엠베하 | 제약 또는 기능식품 투여 형태에 적합한 코팅 조성물 |
| WO2012171884A1 (en) * | 2011-06-17 | 2012-12-20 | Evonik Röhm Gmbh | Gastric resistant pharmaceutical or nutraceutical composition with resistance against the influence of ethanol |
| US9155734B2 (en) * | 2012-03-07 | 2015-10-13 | Mallinckrodt Llc | Stability of hydromorphone hydrochloride solutions |
| KR101847947B1 (ko) | 2013-03-15 | 2018-05-28 | 옵코 아이피 홀딩스 Ⅱ 인코포레이티드 | 안정화되고 변형된 비타민 ｄ 방출 제형 |
| CN103271940B (zh) * | 2013-05-03 | 2014-03-12 | 湖北新济药业有限公司 | 复方金属离子补充剂及其制备方法 |
| UA116405C2 (uk) | 2013-11-13 | 2018-03-12 | Євро-Селтік С.А. | Гідроморфон та налоксон для лікування болю та синдрому опіоїдної дисфункції кишечнику |
| WO2015121189A1 (en) * | 2014-02-17 | 2015-08-20 | Evonik Industries Ag | Pharmaceutical or nutraceutical composition with sustained release characteristic and with resistance against the influence of ethanol |
| EP3193925A2 (en) | 2014-08-07 | 2017-07-26 | OPKO Ireland Global Holdings, Ltd. | Adjunctive therapy with 25-hydroxyvitamin d |
| EP3197436B1 (en) * | 2014-09-24 | 2022-03-09 | Vital Beverages Global Inc. | Compositions and methods for selective gi tract delivery |
| IL290855B1 (en) | 2016-03-28 | 2024-02-01 | Eirgen Pharma Ltd | Treatment methods using vitamin D |
| KR101942922B1 (ko) | 2017-01-20 | 2019-01-30 | 한국해양대학교 산학협력단 | 실리콘 나노입자를 포함하는 리튬이차전지용 음극활물질 및 그 제조방법 |
| CA3075204A1 (en) | 2017-09-14 | 2019-03-21 | Thomas Endres | Polymer and dosage form with sustained release properties and resistance against the influence of ethanol |
| US20210007995A1 (en) | 2018-03-09 | 2021-01-14 | Evonik Operations Gmbh | Polymer mixture with resistance against the influence of ethanol |
| CN114949220B (zh) * | 2022-01-30 | 2023-09-22 | 浙江大学 | 一种靶向损伤节段背根神经节的pH响应镇痛药及其应用 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7374779B2 (en) * | 1999-02-26 | 2008-05-20 | Lipocine, Inc. | Pharmaceutical formulations and systems for improved absorption and multistage release of active agents |
| US20030118641A1 (en) * | 2000-07-27 | 2003-06-26 | Roxane Laboratories, Inc. | Abuse-resistant sustained-release opioid formulation |
| NZ517997A (en) | 1999-08-27 | 2002-11-26 | Southern Res Inst | Injectable, slow release partial opioid agonist or antagonist compositions and their use |
| PL361452A1 (en) * | 2001-07-27 | 2004-10-04 | Yamanouchi Pharmaceutical Co.Ltd. | Compositions containing sustained-release fine grains for tablets quickly disintegrable in the oral cavity and process for producing the same |
| DE10250543A1 (de) * | 2002-10-29 | 2004-05-19 | Röhm GmbH & Co. KG | Mehrschichtige Arzneiform |
| MX2007009162A (es) * | 2005-01-28 | 2007-10-23 | Euro Celtique Sa | Formas de dosis rsistente al alcohol. |
| DE102005024614A1 (de) * | 2005-05-25 | 2006-11-30 | Röhm Gmbh | Verwendung von Polymermischungen zur Herstellung von überzogenen Arzneiformen sowie Arzneiform mit polymerem Mischüberzug |
| CN101370485A (zh) | 2006-01-21 | 2009-02-18 | 艾博特股份有限两合公司 | 用于滥用药物给药的剂型和方法 |
| DE102006051020A1 (de) * | 2006-10-26 | 2008-04-30 | Evonik Röhm Gmbh | Verwendung von (Meth)acrylat-Copolymeren in Retard-Arzneiformen zur Verringerung des Einflusses von Ethanol auf die Wirkstofffreisetzung |
| KR101424653B1 (ko) * | 2007-09-21 | 2014-08-06 | 에보니크 룀 게엠베하 | 에탄올의 영향에 대하여 내성을 가지는 ｐｈ-의존성 조절 방출 제약학적 오피오이드 조성물 |
| US9555006B2 (en) * | 2007-09-21 | 2017-01-31 | Evonik Roehm Gmbh | PH-dependent controlled release pharmaceutical composition for non-opioids with resistance against the influence of ethanol |
-
2008
- 2008-09-24 ES ES08804667.7T patent/ES2532877T3/es active Active
- 2008-09-24 PL PL08804667T patent/PL2341899T3/pl unknown
- 2008-09-24 MX MX2011003047A patent/MX2011003047A/es active IP Right Grant
- 2008-09-24 KR KR1020117006638A patent/KR101528957B1/ko active IP Right Grant
- 2008-09-24 WO PCT/EP2008/062761 patent/WO2010034342A1/en active Application Filing
- 2008-09-24 CN CN200880131222.XA patent/CN102164588B/zh not_active Expired - Fee Related
- 2008-09-24 JP JP2011528191A patent/JP5453433B2/ja not_active Expired - Fee Related
- 2008-09-24 SI SI200831386T patent/SI2341899T1/sl unknown
- 2008-09-24 US US13/062,591 patent/US9757343B2/en active Active
- 2008-09-24 CA CA2738078A patent/CA2738078C/en active Active
- 2008-09-24 EP EP08804667.7A patent/EP2341899B1/en active Active
- 2008-09-24 BR BRPI0823096A patent/BRPI0823096B8/pt not_active IP Right Cessation
-
2011
- 2011-02-20 IL IL211306A patent/IL211306A/en active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| BRPI0823096B8 (pt) | 2022-07-05 |
| CN102164588B (zh) | 2015-07-08 |
| JP5453433B2 (ja) | 2014-03-26 |
| US9757343B2 (en) | 2017-09-12 |
| IL211306A (en) | 2015-01-29 |
| MX2011003047A (es) | 2011-04-14 |
| CA2738078A1 (en) | 2010-04-01 |
| JP2012503608A (ja) | 2012-02-09 |
| PL2341899T3 (pl) | 2015-05-29 |
| US20110217383A1 (en) | 2011-09-08 |
| ES2532877T3 (es) | 2015-04-01 |
| EP2341899B1 (en) | 2014-12-17 |
| KR101528957B1 (ko) | 2015-06-17 |
| BRPI0823096A2 (pt) | 2015-06-16 |
| IL211306A0 (en) | 2011-04-28 |
| CA2738078C (en) | 2015-12-29 |
| EP2341899A1 (en) | 2011-07-13 |
| WO2010034342A1 (en) | 2010-04-01 |
| KR20110058835A (ko) | 2011-06-01 |
| BRPI0823096B1 (pt) | 2019-07-02 |
| CN102164588A (zh) | 2011-08-24 |
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