PL2341899T3 - Opioidowa kompozycja farmaceutyczna o zależnym od pH kontrolowanym uwalnianiu z odpornością na działanie etanolu - Google Patents
Opioidowa kompozycja farmaceutyczna o zależnym od pH kontrolowanym uwalnianiu z odpornością na działanie etanoluInfo
- Publication number
- PL2341899T3 PL2341899T3 PL08804667T PL08804667T PL2341899T3 PL 2341899 T3 PL2341899 T3 PL 2341899T3 PL 08804667 T PL08804667 T PL 08804667T PL 08804667 T PL08804667 T PL 08804667T PL 2341899 T3 PL2341899 T3 PL 2341899T3
- Authority
- PL
- Poland
- Prior art keywords
- ethanol
- influence
- controlled release
- resistance against
- release pharmaceutical
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
- A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/485—Morphinan derivatives, e.g. morphine, codeine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/32—Alcohol-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/36—Opioid-abuse
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP08804667.7A EP2341899B1 (en) | 2008-09-24 | 2008-09-24 | Ph-dependent controlled release pharmaceutical opioid composition with resistance against the influence of ethanol |
| PCT/EP2008/062761 WO2010034342A1 (en) | 2008-09-24 | 2008-09-24 | Ph-dependent controlled release pharmaceutical opioid composition with resistance against the influence of ethanol |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL2341899T3 true PL2341899T3 (pl) | 2015-05-29 |
Family
ID=40691361
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL08804667T PL2341899T3 (pl) | 2008-09-24 | 2008-09-24 | Opioidowa kompozycja farmaceutyczna o zależnym od pH kontrolowanym uwalnianiu z odpornością na działanie etanolu |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US9757343B2 (pl) |
| EP (1) | EP2341899B1 (pl) |
| JP (1) | JP5453433B2 (pl) |
| KR (1) | KR101528957B1 (pl) |
| CN (1) | CN102164588B (pl) |
| BR (1) | BRPI0823096B8 (pl) |
| CA (1) | CA2738078C (pl) |
| ES (1) | ES2532877T3 (pl) |
| IL (1) | IL211306A (pl) |
| MX (1) | MX2011003047A (pl) |
| PL (1) | PL2341899T3 (pl) |
| SI (1) | SI2341899T1 (pl) |
| WO (1) | WO2010034342A1 (pl) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK3095447T3 (da) | 2006-02-03 | 2022-01-31 | Opko Renal Llc | Behandling af vitamin d-insufficiens og -mangel med 25-hydroxyvitamin d2 og 25-hydroxyvitamin d3 |
| PL2679228T3 (pl) | 2006-06-21 | 2018-07-31 | Opko Ireland Global Holdings, Ltd. | Terapia z użyciem środka do uzupełniania witaminy D i środka do zastępowania hormonami witaminy D |
| CN104257667B (zh) | 2007-04-25 | 2019-06-04 | 欧普科Ip 控股Ii 有限公司 | 治疗维生素d不足和缺乏、继发性甲状旁腺功能亢进症和维生素d-响应疾病的方法和组合物 |
| PL2481400T3 (pl) | 2007-04-25 | 2015-04-30 | Opko Ip Holdings Ii Inc | Sposoby i kompozycje dawki doustnej do kontrolowanego uwalniania związku będącego witaminą D |
| EP3225243A1 (en) | 2007-04-25 | 2017-10-04 | Opko Renal, LLC | Method of safely and effectively treating and preventing secondary hyperparathyroidism in chronic kidney disease |
| ES2954932T3 (es) | 2008-04-02 | 2023-11-27 | Eirgen Pharma Ltd | Métodos, composiciones, usos y kits útiles para la deficiencia de vitamina D y trastornos relacionados |
| WO2010105672A1 (en) | 2009-03-18 | 2010-09-23 | Evonik Röhm Gmbh | Controlled release pharmaceutical composition with resistance against the influence of ethanol employing a coating comprising neutral vinyl polymers and excipients |
| CN105796530A (zh) | 2010-03-29 | 2016-07-27 | 赛特克罗公司 | 用于降低甲状旁腺水平的方法和组合物 |
| BR112012028656A2 (pt) | 2010-05-10 | 2016-08-09 | Euro Celtique Sa | combinação de grânulos carregados ativos com ativos adicionais |
| JP5671609B2 (ja) | 2010-05-10 | 2015-02-18 | ユーロ−セルティーク エス．エイ． | ヒドロモルホンおよびナロキソンを含む医薬組成物 |
| WO2011141489A1 (en) | 2010-05-10 | 2011-11-17 | Euro-Celtique S.A. | Manufacturing of active-free granules and tablets comprising the same |
| CN103501767A (zh) * | 2011-06-17 | 2014-01-08 | 赢创罗姆有限公司 | 适合于药物或营养制品剂型的包衣组合物 |
| HUE033111T2 (en) | 2011-06-17 | 2017-11-28 | Evonik Roehm Gmbh | A coating composition for use in pharmaceutical and pharmaceutical dosage forms |
| HUE030548T2 (en) * | 2011-06-17 | 2017-05-29 | Evonik Roehm Gmbh | A stomach-resistant medical or nutritional preparation that is resistant to ethanol |
| US9155734B2 (en) * | 2012-03-07 | 2015-10-13 | Mallinckrodt Llc | Stability of hydromorphone hydrochloride solutions |
| KR101847947B1 (ko) | 2013-03-15 | 2018-05-28 | 옵코 아이피 홀딩스 Ⅱ 인코포레이티드 | 안정화되고 변형된 비타민 ｄ 방출 제형 |
| CN103271940B (zh) * | 2013-05-03 | 2014-03-12 | 湖北新济药业有限公司 | 复方金属离子补充剂及其制备方法 |
| KR102194174B1 (ko) | 2013-11-13 | 2020-12-23 | 유로-셀티큐 에스.에이. | 통증 및 오피오이드 장 기능장애 증후군의 치료를 위한 히드로모르폰 및 날록손 |
| JP6474421B2 (ja) * | 2014-02-17 | 2019-02-27 | エボニック レーム ゲゼルシャフト ミット ベシュレンクテル ハフツングＥｖｏｎｉｋ Ｒｏｅｈｍ ＧｍｂＨ | 持続放出特性を有するとともにエタノールの影響に対する耐性を有する医薬品組成物または栄養機能食品組成物 |
| EP3193925A2 (en) | 2014-08-07 | 2017-07-26 | OPKO Ireland Global Holdings, Ltd. | Adjunctive therapy with 25-hydroxyvitamin d |
| US11229600B2 (en) * | 2014-09-24 | 2022-01-25 | Vital Beverages Global Inc. | Compositions and methods for selective GI tract delivery |
| MX2018011820A (es) | 2016-03-28 | 2019-01-24 | Opko Ireland Global Holdings Ltd | Metodos de tratamiento con vitamina d. |
| KR101942922B1 (ko) | 2017-01-20 | 2019-01-30 | 한국해양대학교 산학협력단 | 실리콘 나노입자를 포함하는 리튬이차전지용 음극활물질 및 그 제조방법 |
| JP2020533468A (ja) | 2017-09-14 | 2020-11-19 | エボニック オペレーションズ ゲーエムベーハー | 持続放出特性およびエタノールの影響に対する耐性を示すポリマーおよび剤形 |
| WO2019170485A1 (en) | 2018-03-09 | 2019-09-12 | Evonik Röhm Gmbh | Polymer mixture with resistance against the influence of ethanol |
| CN114949220B (zh) * | 2022-01-30 | 2023-09-22 | 浙江大学 | 一种靶向损伤节段背根神经节的pH响应镇痛药及其应用 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7374779B2 (en) * | 1999-02-26 | 2008-05-20 | Lipocine, Inc. | Pharmaceutical formulations and systems for improved absorption and multistage release of active agents |
| US20030118641A1 (en) | 2000-07-27 | 2003-06-26 | Roxane Laboratories, Inc. | Abuse-resistant sustained-release opioid formulation |
| DE60015370T2 (de) * | 1999-08-27 | 2006-03-09 | Southern Research Institute, Birmingham | Injizierbare buprenorphinhaltige mikrosphärenzusammensetzungen und ihre verwendung zur reduktion von heroin- und alkoholkonsum |
| ES2351249T3 (es) * | 2001-07-27 | 2011-02-02 | Astellas Pharma Inc. | Composición que comprende partículas finas, de liberación sostenida, para comprimidos de disgregación rápida en la cavidad bucal. |
| DE10250543A1 (de) * | 2002-10-29 | 2004-05-19 | Röhm GmbH & Co. KG | Mehrschichtige Arzneiform |
| CN101132772B (zh) | 2005-01-28 | 2012-05-09 | 欧洲凯尔特公司 | 耐醇剂型 |
| DE102005024614A1 (de) | 2005-05-25 | 2006-11-30 | Röhm Gmbh | Verwendung von Polymermischungen zur Herstellung von überzogenen Arzneiformen sowie Arzneiform mit polymerem Mischüberzug |
| SG169334A1 (en) * | 2006-01-21 | 2011-03-30 | Abbott Gmbh & Co Kg | Dosage form and method for the delivery of drugs of abuse |
| DE102006051020A1 (de) | 2006-10-26 | 2008-04-30 | Evonik Röhm Gmbh | Verwendung von (Meth)acrylat-Copolymeren in Retard-Arzneiformen zur Verringerung des Einflusses von Ethanol auf die Wirkstofffreisetzung |
| BRPI0721990B8 (pt) * | 2007-09-21 | 2022-07-05 | Evonik Roehm Gmbh | composição farmacêutica de liberação controlada dependente de ph, e seu processo de preparação |
| US9555006B2 (en) | 2007-09-21 | 2017-01-31 | Evonik Roehm Gmbh | PH-dependent controlled release pharmaceutical composition for non-opioids with resistance against the influence of ethanol |
-
2008
- 2008-09-24 KR KR1020117006638A patent/KR101528957B1/ko active IP Right Grant
- 2008-09-24 WO PCT/EP2008/062761 patent/WO2010034342A1/en active Application Filing
- 2008-09-24 CA CA2738078A patent/CA2738078C/en active Active
- 2008-09-24 EP EP08804667.7A patent/EP2341899B1/en active Active
- 2008-09-24 BR BRPI0823096A patent/BRPI0823096B8/pt not_active IP Right Cessation
- 2008-09-24 PL PL08804667T patent/PL2341899T3/pl unknown
- 2008-09-24 ES ES08804667.7T patent/ES2532877T3/es active Active
- 2008-09-24 JP JP2011528191A patent/JP5453433B2/ja not_active Expired - Fee Related
- 2008-09-24 US US13/062,591 patent/US9757343B2/en active Active
- 2008-09-24 MX MX2011003047A patent/MX2011003047A/es active IP Right Grant
- 2008-09-24 CN CN200880131222.XA patent/CN102164588B/zh not_active Expired - Fee Related
- 2008-09-24 SI SI200831386T patent/SI2341899T1/sl unknown
-
2011
- 2011-02-20 IL IL211306A patent/IL211306A/en active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| JP2012503608A (ja) | 2012-02-09 |
| IL211306A (en) | 2015-01-29 |
| KR20110058835A (ko) | 2011-06-01 |
| IL211306A0 (en) | 2011-04-28 |
| KR101528957B1 (ko) | 2015-06-17 |
| MX2011003047A (es) | 2011-04-14 |
| EP2341899B1 (en) | 2014-12-17 |
| BRPI0823096B8 (pt) | 2022-07-05 |
| WO2010034342A1 (en) | 2010-04-01 |
| EP2341899A1 (en) | 2011-07-13 |
| CN102164588A (zh) | 2011-08-24 |
| BRPI0823096B1 (pt) | 2019-07-02 |
| CA2738078A1 (en) | 2010-04-01 |
| ES2532877T3 (es) | 2015-04-01 |
| SI2341899T1 (sl) | 2015-04-30 |
| CA2738078C (en) | 2015-12-29 |
| US9757343B2 (en) | 2017-09-12 |
| BRPI0823096A2 (pt) | 2015-06-16 |
| CN102164588B (zh) | 2015-07-08 |
| JP5453433B2 (ja) | 2014-03-26 |
| US20110217383A1 (en) | 2011-09-08 |
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