UA77950C2 - Use of mutants of cc chemokines for treatment of multiple sclerosis - Google Patents

Use of mutants of cc chemokines for treatment of multiple sclerosis Download PDF

Info

Publication number
UA77950C2
UA77950C2 UA2003044038A UA2003044038A UA77950C2 UA 77950 C2 UA77950 C2 UA 77950C2 UA 2003044038 A UA2003044038 A UA 2003044038A UA 2003044038 A UA2003044038 A UA 2003044038A UA 77950 C2 UA77950 C2 UA 77950C2
Authority
UA
Ukraine
Prior art keywords
mutant
chemokine
amino acids
mir
kamte5
Prior art date
Application number
UA2003044038A
Other languages
English (en)
Ukrainian (uk)
Original Assignee
Applied Research Systems
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Applied Research Systems filed Critical Applied Research Systems
Publication of UA77950C2 publication Critical patent/UA77950C2/uk

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19Cytokines; Lymphokines; Interferons
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • C07K14/521Chemokines
    • C07K14/523Beta-chemokines, e.g. RANTES, I-309/TCA-3, MIP-1alpha, MIP-1beta/ACT-2/LD78/SCIF, MCP-1/MCAF, MCP-2, MCP-3, LDCF-1, LDCF-2
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Veterinary Medicine (AREA)
  • Neurosurgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Toxicology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
UA2003044038A 2000-10-04 2001-03-10 Use of mutants of cc chemokines for treatment of multiple sclerosis UA77950C2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP00121665 2000-10-04
PCT/EP2001/011428 WO2002028419A2 (en) 2000-10-04 2001-10-03 Chemokine mutants in the treatment of multiple sclerosis

Publications (1)

Publication Number Publication Date
UA77950C2 true UA77950C2 (en) 2007-02-15

Family

ID=8170011

Family Applications (1)

Application Number Title Priority Date Filing Date
UA2003044038A UA77950C2 (en) 2000-10-04 2001-03-10 Use of mutants of cc chemokines for treatment of multiple sclerosis

Country Status (30)

Country Link
US (1) US7402303B2 (es)
EP (1) EP1326628B1 (es)
JP (1) JP3908165B2 (es)
KR (1) KR100837898B1 (es)
CN (1) CN1285381C (es)
AR (1) AR030854A1 (es)
AT (1) ATE265222T1 (es)
AU (2) AU1591902A (es)
BG (1) BG66137B1 (es)
BR (1) BR0114407A (es)
CA (1) CA2423616C (es)
CZ (1) CZ303409B6 (es)
DE (1) DE60103078T2 (es)
DK (1) DK1326628T3 (es)
EA (1) EA006137B1 (es)
EE (1) EE05174B1 (es)
ES (1) ES2217199T3 (es)
HR (1) HRP20030215B1 (es)
HU (1) HUP0302194A3 (es)
IL (2) IL155178A0 (es)
MX (1) MXPA03003008A (es)
NO (1) NO330278B1 (es)
PL (1) PL204231B1 (es)
PT (1) PT1326628E (es)
RS (1) RS50738B (es)
SI (1) SI1326628T1 (es)
SK (1) SK287523B6 (es)
UA (1) UA77950C2 (es)
WO (1) WO2002028419A2 (es)
ZA (1) ZA200302315B (es)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2320743T3 (es) 2001-12-17 2009-05-28 Laboratoires Serono Sa Mutantes de quimiocina que actuan como antagonistas de quimiocinas.
WO2003084562A1 (en) * 2002-04-04 2003-10-16 Applied Research Systems Ars Holding N.V. Chemokines mutants having improved oral bioavailability
CA2507008A1 (en) * 2002-12-23 2004-07-29 Applied Research Systems Ars Holding N.V. Use of cc-chemokine mutants against liver diseases
ATE415420T1 (de) * 2003-10-22 2008-12-15 Serono Lab Cxcl8-antagonisten
AT412785B (de) * 2003-12-04 2005-07-25 Kungl Andreas J Dr Gag-bindungsproteine
PT1439191E (pt) * 2004-01-19 2006-06-30 Ares Trading Sa Processo para a purificacao de proteinas expressas de forma bacteriana
GB0412400D0 (en) * 2004-06-03 2004-07-07 Univ Newcastle Treatment of inflammatory conditions
EP1760110B1 (en) * 2005-09-03 2011-11-02 Samsung SDI Co., Ltd. Polybenzoxazine-based compound, electrolyte membrane including the same, and fuel cell employing the electrolyte membrane
GB0614755D0 (en) 2006-07-25 2006-09-06 Univ Geneve Cytokine derivatives
US8012474B2 (en) 2007-08-02 2011-09-06 Nov Immune S.A. Anti-RANTES antibodies
EP2539354B1 (en) * 2010-02-08 2017-04-05 The Trustees Of The University Of Pennsylvania Nucleic acid molecules encoding rantes, and compositions comprising and methods of using the same
CN112469430B (zh) 2018-05-28 2024-12-24 日内瓦大学 抑制大脑炎症的方法
US20250186520A1 (en) * 2020-10-26 2025-06-12 City Of Hope Oncolytic virus compositions and methods for the treatment of cancer

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5739103A (en) * 1993-11-12 1998-04-14 Dana-Farber Cancer Institute Chemokine N-terminal deletion mutations
WO1998006751A1 (en) 1996-08-16 1998-02-19 Research Corporation Technologies, Inc. Mcp-3, rantes and mip-1alpha receptor antagonists
EP0906954A1 (en) * 1997-09-29 1999-04-07 Applied Research Systems ARS Holding N.V. Amino-terminal truncated c-c chemokines as chemokine antagonist
DE69832197T2 (de) * 1997-12-23 2006-05-24 Fondazione Centro San Raffaele Del Monte Tabor Rantes-mutanten und therapeutische anwendungen davon
CA2361256A1 (en) * 1999-01-29 2000-08-03 James B. Rottman Method of treating demyelinating inflammatory disease using ccr1 antagonists

Also Published As

Publication number Publication date
IL155178A0 (en) 2003-11-23
MXPA03003008A (es) 2003-07-14
CN1477969A (zh) 2004-02-25
IL155178A (en) 2009-07-20
HUP0302194A2 (hu) 2003-10-28
EA200300439A1 (ru) 2003-08-28
DE60103078D1 (de) 2004-06-03
ZA200302315B (en) 2004-03-25
EP1326628B1 (en) 2004-04-28
JP2004510426A (ja) 2004-04-08
NO20031525D0 (no) 2003-04-03
EA006137B1 (ru) 2005-10-27
ES2217199T3 (es) 2004-11-01
AU1591902A (en) 2002-04-15
US20040101509A1 (en) 2004-05-27
SK287523B6 (sk) 2011-01-04
SK4062003A3 (en) 2003-08-05
CA2423616A1 (en) 2002-04-11
EP1326628A2 (en) 2003-07-16
HRP20030215B1 (en) 2011-09-30
NO20031525L (no) 2003-04-03
EE05174B1 (et) 2009-06-15
DE60103078T2 (de) 2005-04-07
SI1326628T1 (en) 2004-10-31
US7402303B2 (en) 2008-07-22
DK1326628T3 (da) 2004-08-09
ATE265222T1 (de) 2004-05-15
BG66137B1 (bg) 2011-07-29
YU25703A (sh) 2006-05-25
BG107685A (bg) 2003-11-28
HUP0302194A3 (en) 2005-12-28
WO2002028419A3 (en) 2002-06-13
JP3908165B2 (ja) 2007-04-25
CN1285381C (zh) 2006-11-22
PL362350A1 (en) 2004-10-18
PT1326628E (pt) 2004-09-30
AU2002215919B2 (en) 2005-11-24
WO2002028419A2 (en) 2002-04-11
CZ2003947A3 (cs) 2003-11-12
KR100837898B1 (ko) 2008-06-13
KR20030034238A (ko) 2003-05-01
PL204231B1 (pl) 2009-12-31
NO330278B1 (no) 2011-03-21
BR0114407A (pt) 2003-07-29
EE200300139A (et) 2003-06-16
HRP20030215A2 (en) 2005-02-28
HK1062811A1 (en) 2004-11-26
CA2423616C (en) 2010-03-16
AR030854A1 (es) 2003-09-03
RS50738B (sr) 2010-08-31
CZ303409B6 (cs) 2012-09-05

Similar Documents

Publication Publication Date Title
RU2411042C2 (ru) Композиции и способы для лечения острого респираторного синдрома (sars)
US8022176B2 (en) FAS peptide mimetics and uses thereof
UA77950C2 (en) Use of mutants of cc chemokines for treatment of multiple sclerosis
CN110092837B (zh) Uti融合蛋白
JP2007510403A (ja) ケモカイン変異体の治療への使用
CA3091139A1 (en) Dosing for treatment with il-22 fc fusion proteins
EP2358738A2 (en) Modulators of the cx3cr1 receptor and therapeutic uses thereof
AU2002215919A1 (en) Chemokine mutants in the treatment of multiple sclerosis
KR100870296B1 (ko) 융합 단백질
CA2688543C (en) Vegf-d mutants and their use
US20110028399A1 (en) Citrullinated cytokines
US20230303646A1 (en) Analogs of human fibroblast growth factors
US20070161550A1 (en) Antiviral compositions which inhibit paramyxovirus infection
ES2355260T3 (es) Antagonistas de cadherina r selectivos y procedimientos.
WO2005118637A1 (en) Treatment of inflammatory conditions