UA75907C2 - Androgenic 7-substituted-11-halogenated steroids - Google Patents
Androgenic 7-substituted-11-halogenated steroids Download PDFInfo
- Publication number
- UA75907C2 UA75907C2 UA2003087912A UA2003087912A UA75907C2 UA 75907 C2 UA75907 C2 UA 75907C2 UA 2003087912 A UA2003087912 A UA 2003087912A UA 2003087912 A UA2003087912 A UA 2003087912A UA 75907 C2 UA75907 C2 UA 75907C2
- Authority
- UA
- Ukraine
- Prior art keywords
- group
- halogenosteroids
- methylestr
- fluoro
- groups
- Prior art date
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0051—Estrane derivatives
- C07J1/0066—Estrane derivatives substituted in position 17 beta not substituted in position 17 alfa
- C07J1/007—Estrane derivatives substituted in position 17 beta not substituted in position 17 alfa the substituent being an OH group free esterified or etherified
- C07J1/0074—Esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/16—Masculine contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/26—Androgens
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0003—Androstane derivatives
- C07J1/0018—Androstane derivatives substituted in position 17 beta, not substituted in position 17 alfa
- C07J1/0022—Androstane derivatives substituted in position 17 beta, not substituted in position 17 alfa the substituent being an OH group free esterified or etherified
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0003—Androstane derivatives
- C07J1/0018—Androstane derivatives substituted in position 17 beta, not substituted in position 17 alfa
- C07J1/0022—Androstane derivatives substituted in position 17 beta, not substituted in position 17 alfa the substituent being an OH group free esterified or etherified
- C07J1/0025—Esters
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0051—Estrane derivatives
- C07J1/0066—Estrane derivatives substituted in position 17 beta not substituted in position 17 alfa
- C07J1/007—Estrane derivatives substituted in position 17 beta not substituted in position 17 alfa the substituent being an OH group free esterified or etherified
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Endocrinology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Reproductive Health (AREA)
- Diabetes (AREA)
- Gynecology & Obstetrics (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE10104327A DE10104327A1 (de) | 2001-01-24 | 2001-01-24 | 11beta-Halogensteroide, deren Herstellung und Verwendung zur Herstellung von Arzneimitteln sowie 11beta-Halogensteroide enthaltende pharmazeutische Präparate |
PCT/EP2002/000722 WO2002059139A1 (en) | 2001-01-24 | 2002-01-24 | Androgenic 7-substituted 11-halogen steroids |
Publications (1)
Publication Number | Publication Date |
---|---|
UA75907C2 true UA75907C2 (en) | 2006-06-15 |
Family
ID=7672351
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
UA2003087912A UA75907C2 (en) | 2001-01-24 | 2002-01-24 | Androgenic 7-substituted-11-halogenated steroids |
Country Status (34)
Country | Link |
---|---|
US (1) | US7361645B2 (cs) |
EP (1) | EP1353938B1 (cs) |
JP (1) | JP4339591B2 (cs) |
KR (1) | KR100728088B1 (cs) |
CN (1) | CN1234721C (cs) |
AR (1) | AR053299A1 (cs) |
AT (1) | ATE386045T1 (cs) |
AU (1) | AU2002238516B2 (cs) |
BG (1) | BG66133B1 (cs) |
BR (1) | BR0206653A (cs) |
CA (1) | CA2434187C (cs) |
CY (1) | CY1110377T1 (cs) |
CZ (1) | CZ303553B6 (cs) |
DE (2) | DE10104327A1 (cs) |
DK (1) | DK1353938T3 (cs) |
EA (1) | EA006674B1 (cs) |
EE (1) | EE05274B1 (cs) |
ES (1) | ES2300431T3 (cs) |
HR (1) | HRP20030661B1 (cs) |
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IL (2) | IL156807A0 (cs) |
MX (1) | MXPA03006578A (cs) |
NO (1) | NO325754B1 (cs) |
NZ (1) | NZ527041A (cs) |
PE (1) | PE20020848A1 (cs) |
PL (1) | PL207582B1 (cs) |
PT (1) | PT1353938E (cs) |
RS (1) | RS50740B (cs) |
SK (1) | SK287444B6 (cs) |
TW (1) | TWI333494B (cs) |
UA (1) | UA75907C2 (cs) |
UY (1) | UY27133A1 (cs) |
WO (1) | WO2002059139A1 (cs) |
ZA (1) | ZA200306537B (cs) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE10234525A1 (de) * | 2002-07-25 | 2004-02-05 | Schering Ag | Zusammensetzung, enthaltend ein androgenes 11ß-Halogensteroid und ein Gestagen sowie männliches Kontrazeptivum auf Basis dieser Zusammensetzung |
CA2492079C (en) * | 2002-07-24 | 2012-01-10 | Schering Aktiengesellschaft | Microbiological processes for the production of 7 alpha-substituted 11 alpha-hydroxy steroids |
DE10233723A1 (de) | 2002-07-24 | 2004-02-12 | Schering Ag | Mikrobiologische Verfahren zur Herstellung von 7α-substituierten 11α-Hydroxysteroiden, daraus herstellbare 7α,17α-substituierte 11β-Halogensteroide, deren Herstellungsverfahren und Verwendung sowie pharmazeutische Präparate, die diese Verbindungen enthalten, sowie daraus herstellbare 7α-substituierte Estra-1,3,5(10)-triene |
WO2004011008A1 (de) * | 2002-07-25 | 2004-02-05 | Schering Aktiengesellschaft | ZUSAMMENSETZUNG, ENTHALTEND EIN ANDROGENES 11β-HALOGENSTEROID UND EIN GESTAGEN SOWIE MÄNNLICHES KONTRAZEPTIVUM AUF BASIS DIESER ZUSAMMENSETZUNG |
US7879357B2 (en) * | 2003-04-28 | 2011-02-01 | Bayer Schering Pharma Ag | Pharmaceutical composition in the form of a hydrogel for transdermal administration of active ingredients |
JO2492B1 (en) * | 2003-04-28 | 2009-10-05 | شيرينج ايه جي | A pharmaceutical formula in the form of aqueous gel for the skin use of its active ingredients |
CN106188203B (zh) * | 2014-10-08 | 2017-10-24 | 常州大学 | 一种可提高睾酮的收率及大幅减少杂质的合成睾酮方法 |
TWI530504B (zh) * | 2014-12-01 | 2016-04-21 | 臺灣永光化學工業股份有限公司 | 烷基酸睾酮化合物之合成方法 |
US12410209B2 (en) * | 2021-06-29 | 2025-09-09 | Board Of Regents, The University Of Texas System | Modified glucocorticoids |
Family Cites Families (17)
Publication number | Priority date | Publication date | Assignee | Title |
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GB863661A (en) | 1958-06-06 | 1961-03-22 | Upjohn Co | Improvements in or relating to steroids and the manufacture thereof |
CH380118A (de) * | 1959-06-17 | 1964-07-31 | Ciba Geigy | Neue Halogenandrostenverbindungen und Verfahren zu deren Herstellung |
GB1159434A (en) * | 1965-08-16 | 1969-07-23 | Glaxo Lab Ltd | 11beta&;-Fluoro-19-nor-Steroids |
FR1489519A (fr) | 1965-08-16 | 1967-07-21 | Glaxo Lab Ltd | Procédé de préparation de nouveaux 19-nor-stéroïdes et produits obtenus |
US3665021A (en) * | 1966-07-29 | 1972-05-23 | Glaxo Lab Ltd | 9alpha-unsubstituted-11beta-chloro-l9 nos-steroids |
GB1260463A (en) | 1968-01-29 | 1972-01-19 | Glaxo Lab Ltd | 11beta-BROMO-19-NOR-STEROIDS |
DE2410442A1 (de) | 1974-03-01 | 1975-09-11 | Schering Ag | Verfahren zur herstellung von 11-fluorandrostenen |
DE2410443A1 (de) * | 1974-03-01 | 1975-09-11 | Schering Ag | 11beta-fluor-androstene |
DE3214690A1 (de) * | 1982-04-16 | 1983-10-27 | Schering AG, 1000 Berlin und 4709 Bergkamen | 11ss-chlor-(delta)(pfeil hoch)1(pfeil hoch)(pfeil hoch)5(pfeil hoch)-steroide, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate |
GB8721384D0 (en) * | 1987-09-11 | 1987-10-21 | Erba Farmitalia | 17-substituted andro-sta-1 4-dien-3-one derivatives |
US5342834A (en) * | 1989-04-07 | 1994-08-30 | The Population Council, Inc. | Method for androgen supplementation |
US20020012694A1 (en) * | 1997-09-17 | 2002-01-31 | Alfred J. Moo-Young | Transdermal administration of ment |
US6767902B2 (en) * | 1997-09-17 | 2004-07-27 | The Population Council, Inc. | Androgen as a male contraceptive and non-contraceptive androgen replacement |
US5952319A (en) * | 1997-11-26 | 1999-09-14 | Research Triangle Institute | Androgenic steroid compounds and a method of making and using the same |
EP1163259B1 (en) * | 1999-03-08 | 2002-11-20 | Akzo Nobel N.V. | 14.beta.,17-alpha-hydroxymethylandrostane derivatives as androgens |
ES2204613T3 (es) * | 1999-04-06 | 2004-05-01 | Akzo Nobel N.V. | Androgenos 7-alfa alquilo oralmente activos. |
DE19959696A1 (de) * | 1999-12-08 | 2001-06-21 | Jenapharm Gmbh | Ungesättigte 14,15-Cyclopropano-Androstane, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende pharmazeutische Zusammensetzungen |
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2001
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- 2002-01-24 KR KR1020037009732A patent/KR100728088B1/ko not_active Expired - Fee Related
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- 2002-01-24 DE DE60224982T patent/DE60224982T2/de not_active Expired - Lifetime
- 2002-01-24 UA UA2003087912A patent/UA75907C2/uk unknown
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- 2002-01-24 RS YUP-594/03A patent/RS50740B/sr unknown
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2003
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