UA46697C2 - Похідні ксантину і їх фармакологічно переносимі солі - Google Patents

Похідні ксантину і їх фармакологічно переносимі солі Download PDF

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Publication number
UA46697C2
UA46697C2 UA95038235A UA95038235A UA46697C2 UA 46697 C2 UA46697 C2 UA 46697C2 UA 95038235 A UA95038235 A UA 95038235A UA 95038235 A UA95038235 A UA 95038235A UA 46697 C2 UA46697 C2 UA 46697C2
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UA
Ukraine
Prior art keywords
carbon atoms
values
сно
group
substituted
Prior art date
Application number
UA95038235A
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English (en)
Russian (ru)
Ukrainian (uk)
Inventor
Ульріке Кюфнер-Мюль
Ульрике Кюфнер-Мюль
Хельмут Ензінгер
Йоахім Мірау
Йоахим Мирау
Франц-Йозеф Кун
Еріх Лєр
Енціо Мюллєр
Original Assignee
Берінгер Інгельхейм Кг
Берингер Ингельхейм КГ
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Application filed by Берінгер Інгельхейм Кг, Берингер Ингельхейм КГ filed Critical Берінгер Інгельхейм Кг
Publication of UA46697C2 publication Critical patent/UA46697C2/uk

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
    • C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurosurgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Hospice & Palliative Care (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Laser Surgery Devices (AREA)
  • Radiation-Therapy Devices (AREA)
  • Thermotherapy And Cooling Therapy Devices (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
UA95038235A 1992-08-10 1993-08-05 Похідні ксантину і їх фармакологічно переносимі солі UA46697C2 (uk)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE4226371 1992-08-10
DE4238423 1992-11-13
PCT/EP1993/002077 WO1994003456A1 (de) 1992-08-10 1993-08-05 Unsymmetrisch substituierte xanthine mit adenosinantagonistischen eigenschaften

Publications (1)

Publication Number Publication Date
UA46697C2 true UA46697C2 (uk) 2002-06-17

Family

ID=25917371

Family Applications (1)

Application Number Title Priority Date Filing Date
UA95038235A UA46697C2 (uk) 1992-08-10 1993-08-05 Похідні ксантину і їх фармакологічно переносимі солі

Country Status (21)

Country Link
US (1) US5719279A (en:Method)
EP (1) EP0654033A1 (en:Method)
JP (1) JPH08500344A (en:Method)
KR (1) KR950702988A (en:Method)
CN (1) CN1043348C (en:Method)
AU (1) AU681348B2 (en:Method)
BG (1) BG62618B1 (en:Method)
CA (1) CA2140883A1 (en:Method)
CZ (1) CZ286459B6 (en:Method)
FI (1) FI950542A7 (en:Method)
HU (1) HUT65734A (en:Method)
IL (1) IL106624A (en:Method)
MX (1) MX9304819A (en:Method)
NZ (1) NZ254804A (en:Method)
PL (1) PL176389B1 (en:Method)
RU (1) RU2138500C1 (en:Method)
SG (1) SG55038A1 (en:Method)
SK (1) SK18595A3 (en:Method)
TW (1) TW252044B (en:Method)
UA (1) UA46697C2 (en:Method)
WO (1) WO1994003456A1 (en:Method)

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US6821978B2 (en) * 2000-09-19 2004-11-23 Schering Corporation Xanthine phosphodiesterase V inhibitors
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RU2344137C1 (ru) * 2007-07-18 2009-01-20 Государственное образовательное учреждение высшего профессионального образования "БАШКИРСКИЙ ГОСУДАРСТВЕННЫЙ МЕДИЦИНСКИЙ УНИВЕРСИТЕТ Федерального Агентства по здравоохранению и социальному развитию" (ГОУ ВПО БГМУ РОСЗДРАВА) Производные 8-амино-7-(2-гидроксипропил-1)-1,3-диметилксантина гидрохлорида, проявляющие гемореологическую активность
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JP6615109B2 (ja) 2014-02-28 2019-12-04 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング Ｄｐｐ−４阻害薬の医学的使用
CN109310697A (zh) 2016-06-10 2019-02-05 勃林格殷格翰国际有限公司 利格列汀和二甲双胍的组合
RU2643336C1 (ru) * 2016-10-03 2018-01-31 Общество с Ограниченной Ответственностью "Компания "ЭЛТА" СРЕДСТВО, ПРОЯВЛЯЮЩЕЕ АНТИТРОМБОТИЧЕСКИЙ ЭФФЕКТ ПОСРЕДСТВОМ БЛОКИРОВАНИЯ РЕЦЕПТОРОВ ТРОМБОЦИТОВ ГП IIb-IIIa (ВАРИАНТЫ)
CN109796453A (zh) * 2019-02-12 2019-05-24 南京纽邦生物科技有限公司 一种1,7-二甲基黄嘌呤的制备方法
US20240002416A1 (en) 2020-10-15 2024-01-04 Rheinische-Friedrich-Wilhelms-Universität Bonn MRGPRX4 Agonists and Antagonists

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Also Published As

Publication number Publication date
PL176389B1 (pl) 1999-05-31
HU9302302D0 (en) 1993-10-28
CZ34895A3 (en) 1995-10-18
CA2140883A1 (en) 1994-02-17
BG99489A (bg) 1996-01-31
HUT65734A (en) 1994-07-28
CN1086818A (zh) 1994-05-18
FI950542L (fi) 1995-02-08
KR950702988A (ko) 1995-08-23
US5719279A (en) 1998-02-17
AU4707193A (en) 1994-03-03
EP0654033A1 (de) 1995-05-24
SG55038A1 (en) 1998-12-21
IL106624A0 (en) 1993-12-08
IL106624A (en) 1999-01-26
FI950542A0 (fi) 1995-02-08
TW252044B (en:Method) 1995-07-21
RU95109100A (ru) 1996-12-27
CN1043348C (zh) 1999-05-12
PL307397A1 (en) 1995-05-15
WO1994003456A1 (de) 1994-02-17
MX9304819A (es) 1994-02-28
BG62618B1 (bg) 2000-03-31
JPH08500344A (ja) 1996-01-16
FI950542A7 (fi) 1995-02-08
AU681348B2 (en) 1997-08-28
CZ286459B6 (en) 2000-04-12
RU2138500C1 (ru) 1999-09-27
NZ254804A (en) 1997-01-29
SK18595A3 (en) 1995-07-11

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