UA35562C2 - Похідні 7-ізоіндолінілхінолону і 7-ізоіндолінілнафтирідону - Google Patents

Похідні 7-ізоіндолінілхінолону і 7-ізоіндолінілнафтирідону

Info

Publication number
UA35562C2
UA35562C2 UA93003253A UA93003253A UA35562C2 UA 35562 C2 UA35562 C2 UA 35562C2 UA 93003253 A UA93003253 A UA 93003253A UA 93003253 A UA93003253 A UA 93003253A UA 35562 C2 UA35562 C2 UA 35562C2
Authority
UA
Ukraine
Prior art keywords
carbon atoms
derivatives
hydrogen
isoindolinylquinolone
isoindolinylphthyridone
Prior art date
Application number
UA93003253A
Other languages
English (en)
Russian (ru)
Inventor
Томас Філіппс
Томас Филиппс
Стефан Бартел
Андреас КРЕБС
Уве Петерсен
Томас Шенке
Клаус-Дітер БРЕММ
Клаус-Дитер БРЕММ
Райнер Ендерманн
Райнер Эндерманн
Карл Георг Метцгер
Буркхард Мелке
Original Assignee
Байєр Аг
Байер Аг
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Байєр Аг, Байер Аг filed Critical Байєр Аг
Publication of UA35562C2 publication Critical patent/UA35562C2/uk

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44—Iso-indoles; Hydrogenated iso-indoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/06—Peri-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Quinoline Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

Винахід стосується нових похідних хінолону і нафтирідону, зокрема, до похідних 7-ізоіндолінілхінолону і 7-ізоіндолінилфтиридону загальної формули (І) , (I) (I) де: R1 - алкіл з 1-4 атомами вуглецю, незаміщений або заміщений 1-3 атомами фтору, циклоалкіл з 3-6 атомами вуглецю, феніл, незаміщений або заміщений одним або двома атомами фтору, 3-оксапроп-2-іл; R2 - водень; R3 - гідроксил або група O-R11, де R11 означає алкіл з 1-4 атомами вуглецю; R4 - водень, аміногрупа, алкіламіногрупа з 1-4 атомами вуглецю, диалкіламіногрупа з 1-3 атомами вуглецю в кожній алкільній групі; R5 - водень, галоген; R6 - водень, алкілоксикарбоніл з 1-4 атомами вуглецю в алкільній частині
UA93003253A 1992-09-15 1993-09-14 Похідні 7-ізоіндолінілхінолону і 7-ізоіндолінілнафтирідону UA35562C2 (uk)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4230804A DE4230804A1 (de) 1992-09-15 1992-09-15 7-Isoindolinyl-chinolon- und -naphthyridon-Derivate

Publications (1)

Publication Number Publication Date
UA35562C2 true UA35562C2 (uk) 2001-04-16

Family

ID=6467987

Family Applications (1)

Application Number Title Priority Date Filing Date
UA93003253A UA35562C2 (uk) 1992-09-15 1993-09-14 Похідні 7-ізоіндолінілхінолону і 7-ізоіндолінілнафтирідону

Country Status (27)

Country Link
US (3) US5556979A (uk)
EP (1) EP0588166B1 (uk)
JP (1) JP3199930B2 (uk)
KR (1) KR100288522B1 (uk)
CN (1) CN1044118C (uk)
AT (1) ATE138920T1 (uk)
AU (2) AU668743B2 (uk)
CA (2) CA2105923C (uk)
CZ (1) CZ288493B6 (uk)
DE (2) DE4230804A1 (uk)
DK (1) DK0588166T3 (uk)
ES (1) ES2088618T3 (uk)
FI (1) FI934004A (uk)
GR (1) GR3020484T3 (uk)
HU (1) HU222348B1 (uk)
ID (1) ID23959A (uk)
IL (1) IL106990A (uk)
MX (1) MX9305256A (uk)
MY (1) MY131373A (uk)
NO (1) NO304944B1 (uk)
NZ (2) NZ280374A (uk)
PL (3) PL177140B1 (uk)
RU (1) RU2111964C1 (uk)
SK (1) SK282274B6 (uk)
TW (1) TW316899B (uk)
UA (1) UA35562C2 (uk)
ZA (1) ZA936759B (uk)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2769675C2 (ru) * 2020-07-21 2022-04-04 Сергей Иванович Орлов Устройство передачи информации через барьер гальванической развязки

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NO301165B1 (no) * 1992-12-25 1997-09-22 Daiichi Seiyaku Co Bicykliske aminderivater og antibakterielle midler inneholdende disse
DE4301246A1 (de) * 1993-01-19 1994-07-21 Bayer Ag Chinolon- und Naphthyridoncarbonsäurederivate
US5508424A (en) * 1993-03-26 1996-04-16 Ortho Pharmaceutical Corporation 4-arylisoindole analgesics
WO1994025464A1 (en) * 1993-04-24 1994-11-10 Korea Research Institute Of Chemical Technology Novel quinolone carboxylic acid derivatives and process for preparing the same
KR950018003A (ko) * 1993-12-09 1995-07-22 스미스클라인 비참 피엘씨 신규한 퀴놀론 유도체 및 그의 제조 방법
DE4418510A1 (de) * 1994-05-27 1995-11-30 Bayer Ag 1,9-überbrückte Thiazolol[3,4-a]chinolinderivate
DE4427530A1 (de) * 1994-08-04 1996-02-08 Bayer Ag Chinolon- und Naphthyridoncarbonsäure-Derivate
DE4435479A1 (de) * 1994-10-04 1996-04-11 Bayer Ag Chinolon- und Naphthyridoncarbonsäure-Derivate
DE19500792A1 (de) * 1995-01-13 1996-07-18 Bayer Ag Chinolon- und Naphthyridoncarbonsäure-Derivate
EP0726270B1 (de) * 1995-02-09 2001-05-23 Bayer Ag 1,6-Naphthyridoncarbonsäurederivate
DE19506535A1 (de) * 1995-02-09 1996-08-14 Bayer Ag 1,6-Naphthyridoncarbonsäurederivate
DE19722812C2 (de) * 1997-05-30 2003-02-13 Bat Cigarettenfab Gmbh Ultraleicht-Koaxialcigarette mit mehrteiligem Filter
HUP0100051A3 (en) 1997-09-15 2002-08-28 Procter & Gamble Antimicrobial quinolones, their compositions and uses
DE19751948A1 (de) 1997-11-24 1999-05-27 Bayer Ag Verfahren zur Herstellung von 8-Methoxy-Chinoloncarbonsäuren
US6667406B1 (en) * 1999-03-10 2003-12-23 Ortho-Mcneil Pharmaceutical, Inc. Methods for the synthesis of complex reduced isoindole, isooxyindole and isooxyquinoline libraries
PL363301A1 (en) 2000-12-14 2004-11-15 The Procter & Gamble Company Antimicrobial 2-pyridones, their compositions and uses
JP2004515548A (ja) * 2000-12-14 2004-05-27 ザ プロクター アンド ギャンブル カンパニー 抗微生物キノロン
EP1999106B1 (en) * 2006-03-28 2012-06-27 TaiGen Biotechnology Co., Ltd. A hydride reduction process for preparing quinolone intermediates
BRPI0709220A2 (pt) * 2006-03-28 2011-07-12 Procter & Gamble processo de acoplamento para preparo de intermediários de quinolona
MY148393A (en) * 2006-03-28 2013-04-15 Taigen Biotechnology Co Ltd Malate salts, and polymorphs of (3s, 5s)-7-[3-amino-5-methyl-piperidinyl]-1-cyclopropyl-1,4-dihydro-8-methoxy-4-oxo-3-quinolinecarboxylic acid

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2844079B2 (ja) * 1988-05-23 1999-01-06 塩野義製薬株式会社 ピリドンカルボン酸系抗菌剤
JPH0262875A (ja) * 1988-05-23 1990-03-02 Wakunaga Pharmaceut Co Ltd 新規イソインドリン誘導体
CA2030217A1 (en) * 1989-11-21 1991-05-22 Jun Imose Pyridone-carboxylic acid derivatives useful as veterinary medicines
CA2076982A1 (en) * 1990-12-27 1992-06-28 Akira Okura Pyridonecarboxylic acid derivatives
DE4120646A1 (de) * 1991-06-22 1992-12-24 Bayer Ag 7-isoindolinyl-chinolon- und naphthyridoncarbonsaeure-derivate
DE4123918A1 (de) * 1991-07-19 1993-01-21 Bayer Ag 8-vinyl- und 8-ethinyl-chinoloncarbonsaeuren
US5468742A (en) * 1991-07-19 1995-11-21 Bayer Aktiengesellschaft 8-vinyl- and 9-ethinyl-quinolone-carboxylic acids
DE4301246A1 (de) * 1993-01-19 1994-07-21 Bayer Ag Chinolon- und Naphthyridoncarbonsäurederivate
DE4408212A1 (de) * 1994-03-11 1995-09-14 Bayer Ag 5-Vinyl- und 5-Ethinyl-chinolon- und -naphthyridon-carbonsäuren

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2769675C2 (ru) * 2020-07-21 2022-04-04 Сергей Иванович Орлов Устройство передачи информации через барьер гальванической развязки

Also Published As

Publication number Publication date
EP0588166A3 (uk) 1994-04-27
MX9305256A (es) 1995-01-31
SK282274B6 (sk) 2002-01-07
DE4230804A1 (de) 1994-03-17
CZ190393A3 (en) 1994-04-13
ZA936759B (en) 1994-04-11
NZ280374A (en) 1996-08-27
IL106990A0 (en) 1993-12-28
CN1044118C (zh) 1999-07-14
PL177238B1 (pl) 1999-10-29
EP0588166A2 (de) 1994-03-23
US6018054A (en) 2000-01-25
PL300385A1 (en) 1994-03-21
AU6205996A (en) 1996-10-24
DK0588166T3 (da) 1996-10-07
GR3020484T3 (en) 1996-10-31
NZ248631A (en) 1996-01-26
NO304944B1 (no) 1999-03-08
TW316899B (uk) 1997-10-01
CN1087634A (zh) 1994-06-08
JP3199930B2 (ja) 2001-08-20
CA2105923A1 (en) 1994-03-16
RU2111964C1 (ru) 1998-05-27
CZ288493B6 (en) 2001-06-13
MY131373A (en) 2007-08-30
AU668743B2 (en) 1996-05-16
US5739339A (en) 1998-04-14
ATE138920T1 (de) 1996-06-15
AU4492793A (en) 1994-03-24
PL177140B1 (pl) 1999-09-30
ID23959A (id) 1994-03-10
PL177155B1 (pl) 1999-09-30
US5556979A (en) 1996-09-17
CA2469296A1 (en) 1994-03-16
HU222348B1 (hu) 2003-06-28
KR100288522B1 (ko) 2001-05-02
EP0588166B1 (de) 1996-06-05
HU9302593D0 (en) 1993-11-29
SK99093A3 (en) 1994-04-06
JPH06263755A (ja) 1994-09-20
AU682134B2 (en) 1997-09-18
NO933132D0 (no) 1993-09-02
CA2105923C (en) 2004-12-28
FI934004A (fi) 1994-03-16
HUT65216A (en) 1994-05-02
IL106990A (en) 1997-02-18
DE59302809D1 (de) 1996-07-11
ES2088618T3 (es) 1996-08-16
NO933132L (no) 1994-03-16
FI934004A0 (fi) 1993-09-13
KR940007027A (ko) 1994-04-26

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