UA115043C2 - Амідні похідні n-карбамідзаміщених амінокислот як модулятори формілпептидного рецептора 1 (fprl-1) - Google Patents

Амідні похідні n-карбамідзаміщених амінокислот як модулятори формілпептидного рецептора 1 (fprl-1)

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Publication number
UA115043C2
UA115043C2 UAA201405510A UAA201405510A UA115043C2 UA 115043 C2 UA115043 C2 UA 115043C2 UA A201405510 A UAA201405510 A UA A201405510A UA A201405510 A UAA201405510 A UA A201405510A UA 115043 C2 UA115043 C2 UA 115043C2
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UA
Ukraine
Prior art keywords
receptor
fprl
substituted amino
formilpeptide
amydides
Prior art date
Application number
UAA201405510A
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English (en)
Inventor
Річард Л. Бірд
Тьєн Т. Дуонг
Джон Е. ДОНЕЛЛО
Веєна Вісванат
Майкл Е. ГАРСТ
Original Assignee
Аллерган, Інк.
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Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=47116500&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=UA115043(C2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Аллерган, Інк. filed Critical Аллерган, Інк.
Publication of UA115043C2 publication Critical patent/UA115043C2/uk

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    • C07C275/30—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by halogen atoms, or by nitro or nitroso groups
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    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/417—Imidazole-alkylamines, e.g. histamine, phentolamine
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    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/17—Amides, e.g. hydroxamic acids having the group >N—C(O)—N< or >N—C(S)—N<, e.g. urea, thiourea, carmustine
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Abstract

Даний винахід належить до нових амідних похідних N-карбамідзаміщених амінокислот, способів їх одержання, фармацевтичних композицій, що їх містять, а також до їх застосування як фармацевтичних засобів для модуляції N-формілпептидного рецептора 1 (FPRL-1).
UAA201405510A 2011-10-26 2012-10-23 Амідні похідні n-карбамідзаміщених амінокислот як модулятори формілпептидного рецептора 1 (fprl-1) UA115043C2 (uk)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161551772P 2011-10-26 2011-10-26
PCT/US2012/061448 WO2013062947A1 (en) 2011-10-26 2012-10-23 Amide derivatives of n-urea substituted amino acids as formyl peptide receptor like-1 (fprl-1) receptor modulators

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UA115043C2 true UA115043C2 (uk) 2017-09-11

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UAA201405510A UA115043C2 (uk) 2011-10-26 2012-10-23 Амідні похідні n-карбамідзаміщених амінокислот як модулятори формілпептидного рецептора 1 (fprl-1)

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US (9) US8658803B2 (uk)
EP (2) EP3078656B1 (uk)
JP (3) JP5982001B2 (uk)
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