UA111709C2 - Застосування похідних n-бензоїлсерину для запобігання або ослаблення пігментації - Google Patents

Застосування похідних n-бензоїлсерину для запобігання або ослаблення пігментації

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Publication number
UA111709C2
UA111709C2 UAA201208560A UAA201208560A UA111709C2 UA 111709 C2 UA111709 C2 UA 111709C2 UA A201208560 A UAA201208560 A UA A201208560A UA A201208560 A UAA201208560 A UA A201208560A UA 111709 C2 UA111709 C2 UA 111709C2
Authority
UA
Ukraine
Prior art keywords
linear
carbon atoms
prevent
application
pigmentation
Prior art date
Application number
UAA201208560A
Other languages
English (en)
Inventor
Юко Саітох
Тіхіро Кондо
Такасі Ямасакі
Original Assignee
Пола Кемікал Індастріз Інк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Пола Кемікал Індастріз Інк. filed Critical Пола Кемікал Індастріз Інк.
Publication of UA111709C2 publication Critical patent/UA111709C2/uk

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/223—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of alpha-aminoacids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
    • A61K8/442—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof substituted by amido group(s)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/57—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of rings other than six-membered aromatic rings
    • C07C233/63—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of rings other than six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/64—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings
    • C07C233/81—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups
    • C07C233/82—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
    • C07C233/83—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom of an acyclic saturated carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
    • C07C235/42—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton
    • C07C235/44—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton with carbon atoms of carboxamide groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring
    • C07C235/52—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton with carbon atoms of carboxamide groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring having the nitrogen atom of at least one of the carboxamide groups bound to an acyclic carbon atom of a hydrocarbon radical substituted by carboxyl groups

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Birds (AREA)
  • Dermatology (AREA)
  • Emergency Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Cosmetics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Задачею даного винаходу була розробка препарату для нанесення на поверхню шкіри, переважно застосовного для запобігання або ослаблення пігментації. Ця задача була вирішена розробкою засобу для запобігання або ослаблення пігментації, що є сполукою наведеної нижче загальної формули (1), її ізомером і/або її фармакологічно прийнятною сіллю, а також препарату для нанесення на поверхню шкіри, що містить цю сполуку як компонент,, (1)де Rє незаміщеною ароматичною групою або ароматичною групою, яка несе який-небудь замісник; Rозначає атом водню, алкільну групу з лінійним або розгалуженим ланцюгом, що включає 1-4 атоми вуглецю, або ацильну групу з лінійним або розгалуженим алкільним ланцюгом, що включає 1-4 атоми вуглецю; і Rявляє собою атом водню або алкільну групу з лінійним або розгалуженим ланцюгом, що включає 1-4 атоми вуглецю.
UAA201208560A 2009-12-16 2010-12-16 Застосування похідних n-бензоїлсерину для запобігання або ослаблення пігментації UA111709C2 (uk)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2009285001 2009-12-16
PCT/JP2010/072689 WO2011074643A1 (ja) 2009-12-16 2010-12-16 色素沈着予防又は改善剤

Publications (1)

Publication Number Publication Date
UA111709C2 true UA111709C2 (uk) 2016-06-10

Family

ID=44167394

Family Applications (1)

Application Number Title Priority Date Filing Date
UAA201208560A UA111709C2 (uk) 2009-12-16 2010-12-16 Застосування похідних n-бензоїлсерину для запобігання або ослаблення пігментації

Country Status (17)

Country Link
US (2) US20120258063A1 (uk)
EP (1) EP2514402B1 (uk)
JP (1) JP5746977B2 (uk)
KR (1) KR101877575B1 (uk)
CN (1) CN102711720B (uk)
AU (1) AU2010331250B2 (uk)
BR (1) BR112012014196B1 (uk)
CA (1) CA2784308C (uk)
ES (1) ES2604104T3 (uk)
HK (1) HK1173662A1 (uk)
IL (1) IL220413B (uk)
MX (1) MX341841B (uk)
MY (1) MY179437A (uk)
RU (1) RU2564897C2 (uk)
SG (1) SG181702A1 (uk)
UA (1) UA111709C2 (uk)
WO (1) WO2011074643A1 (uk)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5908678B2 (ja) * 2011-06-14 2016-04-26 ポーラ化成工業株式会社 皮膚外用剤
JP6255154B2 (ja) * 2012-12-10 2017-12-27 ポーラ化成工業株式会社 皮膚外用剤
JP6249598B2 (ja) * 2012-12-10 2017-12-20 ポーラ化成工業株式会社 皮膚外用剤
IL248114B (en) * 2014-04-03 2022-07-01 Pola Chem Ind Inc A melanogenesis suppressant containing pentotanyl-d alcohol, skin whitening preparations containing it and its uses
KR101651605B1 (ko) * 2015-12-10 2016-08-26 대봉엘에스 주식회사 신규 페놀산류 유도체 화합물, 및 이의 용도
AU2018370478B2 (en) * 2017-11-15 2024-05-09 Pola Chemical Industries, Inc. Oil-based composition
RU2757906C1 (ru) * 2018-05-29 2021-10-22 Пола Кемикал Индастриз, Инк. Агент для отбеливания кожи

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3091270B2 (ja) 1990-09-28 2000-09-25 協和醗酵工業株式会社 美白化粧料
JP3736405B2 (ja) * 1992-12-21 2006-01-18 味の素株式会社 アミノ酸誘導体及び抗活性酸素剤
JP3091045B2 (ja) 1993-03-04 2000-09-25 丸善製薬株式会社 皮膚化粧料
GB9703201D0 (en) * 1997-02-15 1997-04-02 Zeneca Ltd Chemical compounds
JPH10298151A (ja) * 1997-04-30 1998-11-10 Japan Energy Corp Ｃ型肝炎ウイルスプロテアーゼ阻害剤
JPH1149630A (ja) * 1997-07-31 1999-02-23 Shiseido Co Ltd 美白用化粧料
JP3545173B2 (ja) * 1997-07-31 2004-07-21 アマノ株式会社 ダクト管用粉塵堆積防止装置
US5882665A (en) * 1997-11-18 1999-03-16 Elizabeth Arden Co., Division Of Conopco, Inc. Phytosphingosine salicylates in cosmetic compositions
US6238655B1 (en) 1997-12-15 2001-05-29 The Gillette Company α-amides of L-amino acid as fragrance precursors
JPH11310510A (ja) 1998-04-27 1999-11-09 Kanebo Ltd 保湿剤並びに皮膚化粧料及び入浴剤
JP2001247443A (ja) 2000-03-08 2001-09-11 Kanebo Ltd 皮膚化粧料
JP2002087928A (ja) 2000-09-18 2002-03-27 Kyowa Hakko Kogyo Co Ltd 化粧用保湿剤および化粧料
JPWO2003091211A1 (ja) * 2002-03-28 2005-09-02 住友製薬株式会社 新規ヘテロアリール化合物
DE60328286D1 (de) 2002-05-29 2009-08-20 Lilly Co Eli Vitamin-d-rezeptormodulatoren vom phenyl-thiophen-typ
JP2006511445A (ja) 2002-06-07 2006-04-06 コーティカル・ピーティーワイ・リミテッド マクロファージ遊走阻止因子（ｍｉｆ）のサイトカインまたは生物学的活性を阻害するナフタレン誘導体
CN100558712C (zh) * 2002-06-07 2009-11-11 科蒂科股份有限公司 治疗分子及方法-1
JP4286513B2 (ja) 2002-09-26 2009-07-01 株式会社ファンケル 抗老化用組成物
CA2545296C (en) 2003-12-08 2012-10-16 Galderma Research & Development, S.N.C. Biphenyl derivatives useful as ligands that activate the rar receptors, process for preparing them and use thereof in human medicine and in cosmetics
BRPI0516483A (pt) * 2004-10-15 2008-09-02 Bayer Pharmaceuticals Corp preparo e uso de derivados de ácido bifenil-4-il-carbonilamino para o tratamento de obesidade
US20060166901A1 (en) * 2005-01-03 2006-07-27 Yu Ruey J Compositions comprising O-acetylsalicyl derivatives of aminocarbohydrates and amino acids
JP5014592B2 (ja) * 2005-05-25 2012-08-29 株式会社 資生堂 不全角化抑制剤、毛穴縮小剤，肌荒れ防止・改善剤
WO2007013662A1 (ja) * 2005-07-26 2007-02-01 Shiseido Company, Ltd. しわ防止・改善剤
US8367664B2 (en) 2006-01-24 2013-02-05 Allergan, Inc. Substituted 3-(5-membered unsaturated heterocyclyl-1, 3-dihydro-indol-2-one's and derivatives thereof as kinase inhibitors
KR20090060333A (ko) * 2006-09-08 2009-06-11 노파르티스 아게 림프구 상호작용에 의해 매개되는 질환의 치료에 유용한 ｎ-바이아릴 (헤테로)아릴술폰아미드 유도체

Also Published As

Publication number Publication date
US9414998B2 (en) 2016-08-16
AU2010331250B2 (en) 2015-07-30
US20120258063A1 (en) 2012-10-11
KR101877575B1 (ko) 2018-07-12
BR112012014196B1 (pt) 2023-10-03
EP2514402A4 (en) 2014-05-28
MX2012006925A (es) 2012-07-17
CA2784308A1 (en) 2011-06-23
ES2604104T3 (es) 2017-03-03
IL220413A0 (en) 2012-08-30
JP5746977B2 (ja) 2015-07-08
BR112012014196A2 (pt) 2016-05-31
US20140322150A1 (en) 2014-10-30
MY179437A (en) 2020-11-06
HK1173662A1 (en) 2013-05-24
SG181702A1 (en) 2012-07-30
AU2010331250A1 (en) 2012-08-02
CN102711720A (zh) 2012-10-03
CA2784308C (en) 2017-11-28
EP2514402A1 (en) 2012-10-24
CN102711720B (zh) 2014-08-27
KR20120092709A (ko) 2012-08-21
JPWO2011074643A1 (ja) 2013-04-25
RU2564897C2 (ru) 2015-10-10
IL220413B (en) 2018-07-31
WO2011074643A1 (ja) 2011-06-23
RU2012129932A (ru) 2014-01-27
MX341841B (es) 2016-09-05
EP2514402B1 (en) 2016-08-31

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