UA103025C2 - Твердая композиция лекарственного средства замедленного высвобождения - Google Patents

Твердая композиция лекарственного средства замедленного высвобождения

Info

Publication number
UA103025C2
UA103025C2 UAA201014638A UAA201014638A UA103025C2 UA 103025 C2 UA103025 C2 UA 103025C2 UA A201014638 A UAA201014638 A UA A201014638A UA A201014638 A UAA201014638 A UA A201014638A UA 103025 C2 UA103025 C2 UA 103025C2
Authority
UA
Ukraine
Prior art keywords
delayed release
solid pharmaceutical
pharmaceutical formulation
animals
particularly suitable
Prior art date
Application number
UAA201014638A
Other languages
English (en)
Ukrainian (uk)
Inventor
Венката-Рангарао КАНИКАНТИ
Томас Бах
Михаэль Тройбель
Гертраут Альтройтер
Мартина РЕХАГЕН
Аксель ШМИДТ
Original Assignee
Баер Интеллекчуел Проперти Гмбх
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=40846135&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=UA103025(C2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Баер Интеллекчуел Проперти Гмбх filed Critical Баер Интеллекчуел Проперти Гмбх
Publication of UA103025C2 publication Critical patent/UA103025C2/ru

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4151,2-Diazoles
    • A61K31/41521,2-Diazoles having oxo groups directly attached to the heterocyclic ring, e.g. antipyrine, phenylbutazone, sulfinpyrazone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4985Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • A61K31/662Phosphorus acids or esters thereof having P—C bonds, e.g. foscarnet, trichlorfon
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/15Depsipeptides; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/2027Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/28Dragees; Coated pills or tablets, e.g. with film or compression coating
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/10Anthelmintics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Abstract

Изобретение касается твердой композиции лекарственного средства с замедленным высвобождением активных веществ, пригодной, в частности, для лечения животных.
UAA201014638A 2008-05-07 2009-04-23 Твердая композиция лекарственного средства замедленного высвобождения UA103025C2 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102008022520A DE102008022520A1 (de) 2008-05-07 2008-05-07 Feste Arzneimittelformulierung mit verzögerter Freisetzung
PCT/EP2009/002951 WO2009135593A2 (de) 2008-05-07 2009-04-23 Feste arzneimittelformulierung mit verzögerter freisetzung

Publications (1)

Publication Number Publication Date
UA103025C2 true UA103025C2 (ru) 2013-09-10

Family

ID=40846135

Family Applications (1)

Application Number Title Priority Date Filing Date
UAA201014638A UA103025C2 (ru) 2008-05-07 2009-04-23 Твердая композиция лекарственного средства замедленного высвобождения

Country Status (30)

Country Link
US (2) US20110046072A1 (ru)
EP (1) EP2285359B1 (ru)
JP (1) JP5539966B2 (ru)
KR (1) KR101663501B1 (ru)
CN (1) CN102215824B (ru)
AR (1) AR071620A1 (ru)
AU (1) AU2009243759B2 (ru)
BR (1) BRPI0912428A2 (ru)
CA (1) CA2723553C (ru)
CL (1) CL2009001016A1 (ru)
CO (1) CO6311067A2 (ru)
DE (1) DE102008022520A1 (ru)
DK (1) DK2285359T3 (ru)
DO (1) DOP2010000331A (ru)
EC (1) ECSP10010588A (ru)
ES (1) ES2393169T3 (ru)
HK (1) HK1162936A1 (ru)
IL (1) IL208486A0 (ru)
MX (1) MX2010012025A (ru)
MY (1) MY159492A (ru)
NI (1) NI201000189A (ru)
NZ (1) NZ589017A (ru)
PE (1) PE20091949A1 (ru)
PL (1) PL2285359T3 (ru)
PT (1) PT2285359E (ru)
RU (1) RU2548733C9 (ru)
TW (1) TWI441644B (ru)
UA (1) UA103025C2 (ru)
UY (1) UY31788A (ru)
WO (1) WO2009135593A2 (ru)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102258769B1 (ko) * 2011-10-14 2021-06-01 지엘팜텍주식회사 장용소화효소제 및 그 제조방법
KR101979049B1 (ko) * 2011-12-21 2019-05-15 바이엘 파마 악티엔게젤샤프트 무정형 에모뎁시드를 함유하는 제제
KR101400791B1 (ko) * 2012-10-04 2014-05-29 주식회사대성미생물연구소 동물용 복합 기능성 항생제 조성물
JP6393274B2 (ja) 2012-12-19 2018-09-19 バイエル・アニマル・ヘルス・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツングBayer Animal Health Gmbh 改良された許容性および良好な保存安定性を有する錠剤
EP3265097A4 (en) * 2015-03-03 2018-11-07 Kindred Biosciences Inc. Compositions and methods for treatment and prevention of pyrexia in horses
JP6899330B2 (ja) 2015-04-02 2021-07-07 ベーリンガー インゲルハイム アニマル ヘルス ユーエスエイ インコーポレイテッド 駆虫剤の組合せ及びその使用方法
LT3298027T (lt) 2015-05-20 2021-08-10 Boehringer Ingelheim Animal Health USA Inc. Antihelmintiniai depsipeptido junginiai
SG11201805368YA (en) 2015-12-28 2018-07-30 Merial Inc Anthelmintic depsipeptide compounds
JP6359234B2 (ja) * 2016-06-09 2018-07-18 Dsファーマアニマルヘルス株式会社 動物用徐放性製剤組成物
WO2018093920A1 (en) 2016-11-16 2018-05-24 Merial, Inc. Anthelmintic depsipeptide compounds
CN108888598A (zh) * 2018-08-01 2018-11-27 江西成必信生物科技有限公司 口服易吸收的布他磷及其制备方法
JP7268340B2 (ja) * 2018-12-06 2023-05-08 コニカミノルタ株式会社 3dプリンター成形用樹脂組成物及びそれを用いた成形体とその製造方法

Family Cites Families (47)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2362539C2 (de) 1973-12-17 1986-05-07 Merck Patent Gmbh, 6100 Darmstadt 2-Acyl-4-oxo-1,2,3,6,7,11b-hexahydro-4H-pyrazino[2,1-a]isochinoline, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
EP0134984B1 (en) 1983-07-16 1988-07-13 Beecham Group Plc Benzazepine and benzoxazepine derivatives
NO176766C (no) * 1989-02-07 1995-05-24 Meiji Seika Kaisha Fremgangsmåte for fremstilling av en forbindelse med anthelmintaktivitet
US5120548A (en) * 1989-11-07 1992-06-09 Merck & Co., Inc. Swelling modulated polymeric drug delivery device
NL9000238A (nl) * 1990-01-31 1991-08-16 Aesculaap Bv Veterinair fenytoinepreparaat.
DE4139963A1 (de) * 1991-12-04 1993-06-09 Basf Ag, 6700 Ludwigshafen, De Redispergierbares dispersionspulver aus n-vinylpyrrolidon-vinylacetat-copolymerisat, dessen herstellung und verwendung
JP2874342B2 (ja) 1992-03-17 1999-03-24 藤沢薬品工業株式会社 デプシペプチド誘導体,その製法およびその用途
SE501389C2 (sv) * 1992-04-24 1995-01-30 Leiras Oy Farmaceutiskt preparat och förfarande för dess framställning
DE4317458A1 (de) * 1992-06-11 1993-12-16 Bayer Ag Verwendung von cyclischen Depsipeptiden mit 18 Ringatomen zur Bekämpfung von Endoparasiten, neue cyclische Depsipeptide mit 18 Ringatomen und Verfahren zu ihrer Herstellung
AU666563B2 (en) * 1992-08-07 1996-02-15 Wisconsin Alumni Research Foundation Preparation of 19-nor-vitamin D compounds
JP3140465B2 (ja) * 1992-09-18 2001-03-05 山之内製薬株式会社 ハイドロゲル徐放性製剤
KR100309091B1 (ko) 1993-02-19 2001-12-28 이치로 키타사토 환상 데프시펩티드 pf 1022의 유도체
DE4317457A1 (de) * 1993-05-26 1994-12-01 Bayer Ag Octacyclodepsipeptide mit endoparasitizider Wirkung
DE4317432A1 (de) 1993-05-26 1994-12-01 Bayer Ag Octacyclodepsipeptide mit endoparasitizider Wirkung
AU686222B2 (en) 1993-09-06 1998-02-05 Astellas Pharma Inc. Cyclodepsipeptide compound
DE4401389A1 (de) * 1994-01-19 1995-07-20 Bayer Ag Verwendung von cyclischen Depsipeptiden mit 12 Ringatomen zur Bekämpfung von Endoparasiten, neue cyclische Depsipeptide mit 12 Ringatomen und Verfahren zu ihrer Herstellung
DE4406025A1 (de) 1994-02-24 1995-08-31 Bayer Ag Milchsäure-haltige cyclische Depsipeptide mit 18 Ringatomen als endoparasitizide Mittel und Verfahren zu ihrer Herstellung
US5747446A (en) * 1994-03-22 1998-05-05 Beth Israel Deaconess Medical Center Modified polypeptides with increased biological activity
KR100232297B1 (ko) * 1994-05-06 1999-12-01 디. 제이. 우드 아지트로마이신의 제어된 방출 투여형 제제
DE4437198A1 (de) 1994-10-18 1996-04-25 Bayer Ag Verfahren zur Sulfonylierung, Sulfenylierung und Phosphorylierung von cyclischen Depsipeptiden
EP0872481B1 (en) 1995-06-30 2009-03-18 Astellas Pharma Inc. Depsipeptide derivative, process for production thereof, and novel intermediate therefor
DE19531684A1 (de) * 1995-08-29 1997-03-06 Bayer Ag Verfahren zur Herstellung von Arzneimittelzubereitungen mit kontrollierter Freisetzung
EP0903347B1 (en) 1995-09-22 2005-07-20 Meiji Seika Kaisha Ltd. Novel cyclic depsipeptide pf1022 derivatives
DE19545639A1 (de) 1995-12-07 1997-06-12 Bayer Ag Verfahren zur Herstellung von substituierten Arylmilchsäure-haltigen Cyclodepsipeptiden mit 24 Ringatomen
AUPP279698A0 (en) * 1998-04-03 1998-04-30 Sunscape Developments Limited Sustained release formulation
IT1303693B1 (it) * 1998-11-03 2001-02-23 Formenti Farmaceutici Spa Composizioni a rilascio controllato di metamizolo.
DE19920415A1 (de) * 1999-05-04 2000-11-09 Hexal Ag Metamizol enthaltende, kontrolliert freisetzende pharmazeutische Zusammensetzung
UY26615A1 (es) * 2000-03-16 2001-10-25 Pfizer Prod Inc Inhibidor de la glucogeno fosforilasa.
DE10031044A1 (de) * 2000-06-26 2002-01-03 Bayer Ag Endoparasitizide Mittel zur freiwilligen oralen Aufnahme durch Tiere
HUP0401079A3 (en) * 2001-07-10 2008-04-28 Teva Pharma Drug delivery system for zero order, zero order-biphasic, ascending or descending drug delivery
US20030190343A1 (en) * 2002-03-05 2003-10-09 Pfizer Inc. Palatable pharmaceutical compositions for companion animals
DE10212864B4 (de) * 2002-03-22 2005-12-22 Beiersdorf Ag Polymermatrizes umfassend ein Mischsystem zur Löslichkeitsvermittlung von pharmazeutischen Wirkstoffen, Verfahren zu deren Herstellung und deren Verwendung
US20040037869A1 (en) * 2002-08-16 2004-02-26 Douglas Cleverly Non-animal product containing veterinary formulations
MXPA05010338A (es) * 2003-04-02 2005-11-17 Boehringer Ingelheim Int Composiciones farmaceuticas para inhibidores de la proteasa del virus de la hepatitis c.
TR200300510A2 (tr) * 2003-04-18 2004-11-22 Sanovel �La� Sanay� Ve T�Caret A.�. Dağılan alendronat mikropartikül formülasyonu
US20050053658A1 (en) * 2003-09-09 2005-03-10 Venkatesh Gopi M. Extended release systems for macrolide antibiotics
US7396819B2 (en) * 2003-08-08 2008-07-08 Virbac Corporation Anthelmintic formulations
DE10351448A1 (de) * 2003-11-04 2005-06-09 Bayer Healthcare Ag Geschmackstoffhaltige Arzneimittelformulierungen mit verbesserten pharmazeutischen Eigenschaften
EP1694305B1 (en) * 2003-12-01 2019-10-16 Recordati Ireland Limited Pharmaceutical compositions comprising lercanidipine
DE10358525A1 (de) * 2003-12-13 2005-07-07 Bayer Healthcare Ag Endoparasitizide Mittel zur topischen Applikation
DE102004055316A1 (de) * 2004-11-16 2006-05-18 Bayer Healthcare Ag Verhinderung vertikaler Endoparasiten-Infektionen
AR055106A1 (es) * 2005-08-05 2007-08-08 Osmotica Pharmaceutical Argent Composicion farmaceutica solida de liberacion extendida que contiene carbidopa y levodopa
US8158152B2 (en) * 2005-11-18 2012-04-17 Scidose Llc Lyophilization process and products obtained thereby
AU2007247480B8 (en) * 2006-04-28 2013-04-11 Grunenthal Gmbh Pharmaceutical combination comprising 3- (3-dimethylamino-1-ethyl-2-methyl-propyl) -phenol and an NSAID
CN101495097A (zh) * 2006-07-26 2009-07-29 旭化成化学株式会社 球形素颗粒及其制造方法
DE102006044694A1 (de) * 2006-09-22 2008-03-27 Krewel Meuselbach Gmbh Perorale feste Schmerzmittelzubereitung
DE102007012644A1 (de) * 2007-03-16 2008-09-18 Bayer Healthcare Ag Stabilisierung von Vitamin B12

Also Published As

Publication number Publication date
US20110046072A1 (en) 2011-02-24
AU2009243759A1 (en) 2009-11-12
AU2009243759B2 (en) 2015-04-16
KR101663501B1 (ko) 2016-10-07
HK1162936A1 (en) 2012-09-07
CO6311067A2 (es) 2011-08-22
ECSP10010588A (es) 2010-12-30
JP5539966B2 (ja) 2014-07-02
CA2723553A1 (en) 2009-11-12
DOP2010000331A (es) 2010-12-15
BRPI0912428A2 (pt) 2016-02-16
EP2285359A2 (de) 2011-02-23
NZ589017A (en) 2012-11-30
PT2285359E (pt) 2012-11-26
RU2010149561A (ru) 2012-06-20
PL2285359T3 (pl) 2013-01-31
WO2009135593A2 (de) 2009-11-12
RU2548733C2 (ru) 2015-04-20
TWI441644B (zh) 2014-06-21
WO2009135593A3 (de) 2011-01-06
TW201010714A (en) 2010-03-16
EP2285359B1 (de) 2012-09-05
IL208486A0 (en) 2010-12-30
CA2723553C (en) 2016-08-30
NI201000189A (es) 2011-08-10
CN102215824A (zh) 2011-10-12
CN102215824B (zh) 2015-06-03
JP2011519878A (ja) 2011-07-14
CL2009001016A1 (es) 2010-08-13
PE20091949A1 (es) 2009-12-25
DE102008022520A1 (de) 2009-11-12
RU2548733C9 (ru) 2015-12-20
US20150150985A1 (en) 2015-06-04
DK2285359T3 (da) 2012-11-26
ES2393169T3 (es) 2012-12-19
UY31788A (es) 2009-12-14
AR071620A1 (es) 2010-06-30
KR20110015592A (ko) 2011-02-16
MY159492A (en) 2017-01-13
MX2010012025A (es) 2010-12-07

Similar Documents

Publication Publication Date Title
UA103025C2 (ru) Твердая композиция лекарственного средства замедленного высвобождения
EP2130552A4 (en) PHARMACEUTICAL COMPOSITION COMPRISING AN ANTI-GRP78 ANTIBODY AS AN ACTIVE SUBSTANCE
IL225637A0 (en) The compositions, tablets containing such compositions, their use and a process for their preparation
EP2522653A4 (en) BIGUANIDE DERIVATIVE, PROCESS FOR PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE BIGUANIDE DERIVATIVE AS AN ACTIVE SUBSTANCE
WO2011130615A3 (en) Preparation of lacosamide
ZA201005015B (en) Solid pharmaceutical dosage form
WO2010021607A3 (en) Pharmaceutical formulation
IL211018A (en) Inhibitors, processes for making them, medicinal preparations containing them and their use
EP2447253A4 (en) DIHYDROPYRIMIDIN COMPOUNDS AND MANUFACTURING METHOD, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF
EP2468771A4 (en) PHARMACEUTICAL COMPOSITION WITH AN ANTIBODY TO HB-EGF AS AN ACTIVE SUBSTANCE
EP2241569A4 (en) THIENOPYRIDAZINE COMPOUNDS, PREPARATIONS THEREOF, PHARMACEUTICAL COMPOSITIONS AND USES
HK1182934A1 (zh) 種抗疲勞的組合物及其製劑和應用
EP2383262A4 (en) PHENYLPYRIMIDONE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, METHOD OF MANUFACTURE AND APPLICATIONS THEREOF
MX344846B (es) Combinacion de granulos cargados activos con activos adicionales.
HK1152651A1 (en) Stable pharmaceutical formulation with limited discoloration
WO2011002422A3 (en) Solubility enhancing pharmaceutical formulation
IL208151A0 (en) Long-term stable pharmaceutical preparation having the active ingredient glycerol trinitrate
IL208788A (en) Pharmacy-based formulation
HK1152652A1 (en) Pharmaceutical solid preparation having active ingredients separated by boundary therein
IL212171A (en) 1-Phenylpyrol compounds, pharmaceuticals containing them and their use
MX2011006721A (es) Formulacion farmaceutica de fenofibrato nanonizado.
MX2014006201A (es) Formas de dosificaciones solidas de imatinib reconstituidas justo antes de usarse.
TR200909785A1 (tr) Aktif ajan olarak sefdinir içeren farmasötik kompozisyonlar.
IL207205A0 (en) Triazolopyridazines as par1 inhibitors, their preparation and use as medicaments
ZA201005316B (en) 2-amino-2-phenyl-alkanol derivatives, their preparation and pharmaceutical compositions containing them