TWI702232B - Pd-1結合蛋白及其使用方法 - Google Patents

Pd-1結合蛋白及其使用方法 Download PDF

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TWI702232B
TWI702232B TW105131416A TW105131416A TWI702232B TW I702232 B TWI702232 B TW I702232B TW 105131416 A TW105131416 A TW 105131416A TW 105131416 A TW105131416 A TW 105131416A TW I702232 B TWI702232 B TW I702232B
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antibody
seq
antigen
binding fragment
acid sequence
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TW105131416A
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TW201718653A (zh
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布萊登 班奈特
菲利浦 保羅 簡柏蘭
坎德薩米 海瑞哈倫
拜爾吉姆 傑克森
瑪莉恩 凱瑞
蘿利 凱特瑞
慧羚 梁
莉莎 摩瑞森
廷勳 宣
莎娜 多瑞斯
顯理 陳
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美商西建公司
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    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2818Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD28 or CD152
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
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    • C07K2317/00Immunoglobulins specific features
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    • C07K2317/00Immunoglobulins specific features
    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

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  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
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TW105131416A 2015-09-29 2016-09-29 Pd-1結合蛋白及其使用方法 TWI702232B (zh)

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US201562234535P 2015-09-29 2015-09-29
US62/234,535 2015-09-29

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TWI702232B true TWI702232B (zh) 2020-08-21

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US (3) US10428145B2 (enExample)
EP (1) EP3355920A4 (enExample)
JP (2) JP6843868B2 (enExample)
KR (1) KR20180054824A (enExample)
CN (1) CN108289953B (enExample)
AR (1) AR106184A1 (enExample)
AU (1) AU2016332725A1 (enExample)
BR (1) BR112018006237A2 (enExample)
CA (1) CA2997963A1 (enExample)
CL (1) CL2018000778A1 (enExample)
CO (1) CO2018003973A2 (enExample)
EA (1) EA201890790A1 (enExample)
EC (1) ECSP18030970A (enExample)
HK (1) HK1251158A1 (enExample)
IL (1) IL258273A (enExample)
MX (1) MX2018003689A (enExample)
TW (1) TWI702232B (enExample)
WO (1) WO2017058859A1 (enExample)

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