TWI488839B - 作爲孤兒核受體RORγ調節物之經甲醯胺或磺醯胺取代之含氮5員雜環 - Google Patents
作爲孤兒核受體RORγ調節物之經甲醯胺或磺醯胺取代之含氮5員雜環 Download PDFInfo
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- TWI488839B TWI488839B TW102119213A TW102119213A TWI488839B TW I488839 B TWI488839 B TW I488839B TW 102119213 A TW102119213 A TW 102119213A TW 102119213 A TW102119213 A TW 102119213A TW I488839 B TWI488839 B TW I488839B
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| TW201803869A (zh) | 2016-04-27 | 2018-02-01 | 健生藥品公司 | 作為RORγT調節劑之6-胺基吡啶-3-基噻唑 |
| EP3526209B1 (en) * | 2016-10-12 | 2025-04-16 | Research Triangle Institute | Heterocyclic apelin receptor (apj) agonists and uses thereof |
| TW201822637A (zh) | 2016-11-07 | 2018-07-01 | 德商拜耳廠股份有限公司 | 用於控制動物害蟲的經取代磺醯胺類 |
| JP2020059651A (ja) * | 2016-12-26 | 2020-04-16 | 科研製薬株式会社 | ピラゾール誘導体及びそれを含有する医薬 |
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| CN109485595B (zh) * | 2017-09-12 | 2022-05-27 | 江苏恒瑞医药股份有限公司 | 亲水性基团取代的吲哚甲酰胺类衍生物、其制备方法及其在医药上的应用 |
| CN111094278B (zh) | 2017-09-13 | 2023-07-14 | 诺华股份有限公司 | 二苯基衍生物及其用途 |
| TW202000650A (zh) * | 2018-02-28 | 2020-01-01 | 日商日本煙草產業股份有限公司 | 4-甲基二氫嘧啶酮化合物及其醫藥用途 |
| ES2928246T3 (es) * | 2018-06-18 | 2022-11-16 | Janssen Pharmaceutica Nv | 6-aminopiridin-3-il pirazoles como moduladores de RORyt |
| CN112292373A (zh) * | 2018-06-18 | 2021-01-29 | 詹森药业有限公司 | 作为RORγt的调节剂的吡啶基吡唑类 |
| US10975037B2 (en) * | 2018-06-18 | 2021-04-13 | Janssen Pharmaceutica Nv | Phenyl substituted pyrazoles as modulators of RORγt |
| JP2021527660A (ja) * | 2018-06-18 | 2021-10-14 | ヤンセン ファーマシューティカ エヌ.ベー. | RORγtのモジュレータとしてのフェニル及びピリジニル置換イミダゾール |
| CN111484505B (zh) * | 2019-01-28 | 2022-11-15 | 正大天晴药业集团股份有限公司 | 一种双环RORγ抑制剂的盐酸盐结晶型 |
| CN114502545B (zh) | 2019-07-23 | 2024-06-28 | 拜耳公司 | 作为农药的新的杂芳基-三唑化合物 |
| WO2021089673A1 (de) | 2019-11-07 | 2021-05-14 | Bayer Aktiengesellschaft | Substituierte sulfonylamide zur bekämpfung tierischer schädlinge |
| TW202136248A (zh) | 2019-11-25 | 2021-10-01 | 德商拜耳廠股份有限公司 | 作為殺蟲劑之新穎雜芳基-三唑化合物 |
| TWI891782B (zh) | 2020-05-06 | 2025-08-01 | 德商拜耳廠股份有限公司 | 作為殺蟲劑之新穎雜芳基三唑化合物 |
| EP4212531A1 (en) | 2022-01-14 | 2023-07-19 | AGV Discovery | Azaindole derivatives and their use as erk kinase inhibitors |
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