EA027953B9 - АЗОТСОДЕРЖАЩИЕ 5-ЧЛЕННЫЕ ГЕТЕРОЦИКЛЫ, ЗАМЕЩЕННЫЕ КАРБОКСАМИДОМ ИЛИ СУЛЬФОНАМИДОМ, В КАЧЕСТВЕ МОДУЛЯТОРОВ ДЛЯ ЯДЕРНОГО ОРФАНОВОГО РЕЦЕПТОРА RORγ - Google Patents

АЗОТСОДЕРЖАЩИЕ 5-ЧЛЕННЫЕ ГЕТЕРОЦИКЛЫ, ЗАМЕЩЕННЫЕ КАРБОКСАМИДОМ ИЛИ СУЛЬФОНАМИДОМ, В КАЧЕСТВЕ МОДУЛЯТОРОВ ДЛЯ ЯДЕРНОГО ОРФАНОВОГО РЕЦЕПТОРА RORγ

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Publication number
EA027953B9
EA027953B9 EA201590092A EA201590092A EA027953B9 EA 027953 B9 EA027953 B9 EA 027953B9 EA 201590092 A EA201590092 A EA 201590092A EA 201590092 A EA201590092 A EA 201590092A EA 027953 B9 EA027953 B9 EA 027953B9
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Eurasian Patent Office
Prior art keywords
modulators
nuclear receptor
carboxamide
orphan nuclear
substituted nitrogen
Prior art date
Application number
EA201590092A
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English (en)
Russian (ru)
Other versions
EA027953B1 (ru
EA201590092A1 (ru
Inventor
Кристиан Геге
Олаф КИНЦЕЛЬ
Кристоф Штеенек
Джеральд Клейманн
Томас ХОФФМАНН
Original Assignee
Фенекс Фармасьютикалз Аг
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=46754230&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EA027953(B9) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Фенекс Фармасьютикалз Аг filed Critical Фенекс Фармасьютикалз Аг
Publication of EA201590092A1 publication Critical patent/EA201590092A1/ru
Publication of EA027953B1 publication Critical patent/EA027953B1/ru
Publication of EA027953B9 publication Critical patent/EA027953B9/ru

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    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
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    • A61K31/401—Proline; Derivatives thereof, e.g. captopril
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    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
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    • C07D249/10—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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  • Nitrogen Condensed Heterocyclic Rings (AREA)
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EA201590092A 2012-08-09 2013-05-29 АЗОТСОДЕРЖАЩИЕ 5-ЧЛЕННЫЕ ГЕТЕРОЦИКЛЫ, ЗАМЕЩЕННЫЕ КАРБОКСАМИДОМ ИЛИ СУЛЬФОНАМИДОМ, В КАЧЕСТВЕ МОДУЛЯТОРОВ ДЛЯ ЯДЕРНОГО ОРФАНОВОГО РЕЦЕПТОРА RORγ EA027953B9 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261681296P 2012-08-09 2012-08-09
EP12005789 2012-08-09
PCT/EP2013/001594 WO2014023367A1 (en) 2012-08-09 2013-05-29 Carboxamide or sulfonamide substituted nitrogen-containing 5-membered heterocycles as modulators for the orphan nuclear receptor ror gamma

Publications (3)

Publication Number Publication Date
EA201590092A1 EA201590092A1 (ru) 2015-08-31
EA027953B1 EA027953B1 (ru) 2017-09-29
EA027953B9 true EA027953B9 (ru) 2018-01-31

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EA201590092A EA027953B9 (ru) 2012-08-09 2013-05-29 АЗОТСОДЕРЖАЩИЕ 5-ЧЛЕННЫЕ ГЕТЕРОЦИКЛЫ, ЗАМЕЩЕННЫЕ КАРБОКСАМИДОМ ИЛИ СУЛЬФОНАМИДОМ, В КАЧЕСТВЕ МОДУЛЯТОРОВ ДЛЯ ЯДЕРНОГО ОРФАНОВОГО РЕЦЕПТОРА RORγ

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CO (1) CO7310529A2 (enExample)
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