TWI448464B - 聚(adp-核糖)聚合酶(parp)之二氫吡啶并酞嗪酮抑制劑 - Google Patents

聚(adp-核糖)聚合酶(parp)之二氫吡啶并酞嗪酮抑制劑 Download PDF

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TWI448464B
TWI448464B TW098126400A TW98126400A TWI448464B TW I448464 B TWI448464 B TW I448464B TW 098126400 A TW098126400 A TW 098126400A TW 98126400 A TW98126400 A TW 98126400A TW I448464 B TWI448464 B TW I448464B
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Taiwan
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phenyl
dihydro
pyrido
methyl
group
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TW098126400A
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Chinese (zh)
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TW201018688A (en
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Bing Wang
Daniel Chu
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Biomarin Pharm Inc
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    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
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    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/50Pyridazines; Hydrogenated pyridazines
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    • A61K31/53771,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
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    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
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TW098126400A 2008-08-06 2009-08-05 聚(adp-核糖)聚合酶(parp)之二氫吡啶并酞嗪酮抑制劑 TWI448464B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US8668708P 2008-08-06 2008-08-06
US15103609P 2009-02-09 2009-02-09
US17308809P 2009-04-27 2009-04-27

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TW201018688A TW201018688A (en) 2010-05-16
TWI448464B true TWI448464B (zh) 2014-08-11

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TW098126400A TWI448464B (zh) 2008-08-06 2009-08-05 聚(adp-核糖)聚合酶(parp)之二氫吡啶并酞嗪酮抑制劑
TW103106940A TW201422617A (zh) 2008-08-06 2009-08-05 聚(adp-核糖)聚合酶(parp)之二氫吡啶并酞嗪酮抑制劑

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TW103106940A TW201422617A (zh) 2008-08-06 2009-08-05 聚(adp-核糖)聚合酶(parp)之二氫吡啶并酞嗪酮抑制劑

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Country Link
US (7) US8012976B2 (enExample)
EP (3) EP2767537B1 (enExample)
JP (3) JP5984389B2 (enExample)
KR (1) KR101846029B1 (enExample)
CN (3) CN104478875B (enExample)
AR (1) AR072970A1 (enExample)
AU (1) AU2009279944B2 (enExample)
BR (1) BRPI0917119B1 (enExample)
CA (1) CA2732797C (enExample)
CY (3) CY1115022T1 (enExample)
DK (2) DK2326650T3 (enExample)
ES (2) ES2625817T3 (enExample)
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GB (1) GB2462361A (enExample)
HR (1) HRP20170982T1 (enExample)
HU (2) HUE035295T2 (enExample)
IL (1) IL211070A (enExample)
LT (2) LT2767537T (enExample)
LU (1) LUC00140I2 (enExample)
MX (1) MX2011001328A (enExample)
NL (1) NL301021I2 (enExample)
NO (1) NO2019042I1 (enExample)
NZ (1) NZ591166A (enExample)
PL (2) PL2767537T3 (enExample)
PT (2) PT2767537T (enExample)
SG (2) SG193842A1 (enExample)
SI (2) SI2326650T1 (enExample)
SM (1) SMT201700312T1 (enExample)
TW (2) TWI448464B (enExample)
WO (1) WO2010017055A2 (enExample)
ZA (1) ZA201100897B (enExample)

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