TWI308492B - - Google Patents
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- TWI308492B TWI308492B TW091102095A TW91102095A TWI308492B TW I308492 B TWI308492 B TW I308492B TW 091102095 A TW091102095 A TW 091102095A TW 91102095 A TW91102095 A TW 91102095A TW I308492 B TWI308492 B TW I308492B
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- trap
- decoy
- ointment
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- skin
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Classifications
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7088—Compounds having three or more nucleosides or nucleotides
- A61K31/711—Natural deoxyribonucleic acids, i.e. containing only 2'-deoxyriboses attached to adenine, guanine, cytosine or thymine and having 3'-5' phosphodiester links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/04—Antipruritics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/13—Decoys
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
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- Biomedical Technology (AREA)
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- General Chemical & Material Sciences (AREA)
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- Epidemiology (AREA)
- Biotechnology (AREA)
- Wood Science & Technology (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Dermatology (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Marine Sciences & Fisheries (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Microbiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2001044350 | 2001-02-20 |
Publications (1)
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| TWI308492B true TWI308492B (enExample) | 2009-04-11 |
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Country Status (11)
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| EP (2) | EP1690544B1 (enExample) |
| JP (2) | JP3778357B2 (enExample) |
| AT (1) | ATE390938T1 (enExample) |
| CY (1) | CY1108165T1 (enExample) |
| DE (1) | DE60225899T2 (enExample) |
| DK (1) | DK1362600T3 (enExample) |
| ES (1) | ES2307733T3 (enExample) |
| PT (1) | PT1362600E (enExample) |
| TW (1) | TWI308492B (enExample) |
| WO (1) | WO2002066070A1 (enExample) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE69435100D1 (de) * | 1993-10-29 | 2008-06-26 | Brigham & Womens Hospital | Therapeutische verwendung von cis-element-fallen in vivo |
| PT1362600E (pt) | 2001-02-20 | 2008-07-09 | Anges Mg Inc | Utilização tópica de iscos de nf-kb para o tratamento da dermatite atópica |
| DE10148886A1 (de) * | 2001-10-04 | 2003-04-30 | Avontec Gmbh | Inhibition von STAT-1 |
| WO2004110533A1 (ja) * | 2003-05-09 | 2004-12-23 | Anges Mg, Inc. | 薬剤が収容された針無注射器 |
| WO2005004913A1 (ja) * | 2003-07-09 | 2005-01-20 | Anges Mg, Inc. | デコイを含む薬学的組成物およびその使用方法 |
| AU2004268457A1 (en) * | 2003-08-29 | 2005-03-10 | Anges Mg, Inc. | Gene therapy for skin disorders using needleless syringes |
| US7378509B2 (en) * | 2003-12-02 | 2008-05-27 | Anesiva, Inc. | NF-kappaB oligonucleotide decoy molecules |
| WO2005084180A2 (en) | 2003-12-19 | 2005-09-15 | University Of Cincinnati | Polyamides and polyamide complexes for delivery of oligonucleotide decoys |
| EP1799271A4 (en) * | 2004-09-21 | 2010-05-05 | Anesiva Inc | DISPOSAL OF POLYNUCLEOTIDES |
| ATE509100T1 (de) | 2004-10-22 | 2011-05-15 | Anges Mg Inc | Chimäre (doppel-) attrappe |
| US20060258604A1 (en) * | 2005-05-10 | 2006-11-16 | Warren Strober | Compositions and methods for the treatment of inflammatory bowel disease utilizing NF-kappaB decoy polynucleotides |
| US20090214630A1 (en) * | 2005-05-10 | 2009-08-27 | Warren Strober | Compositions and Methods for the Treatment of Inflammatory Bowel Disease Utilizing NF-KappaB Decoy Polynucleotides |
| CA2614295A1 (en) * | 2005-06-06 | 2006-12-14 | Anges Mg, Inc. | Transcription factor decoy |
| US20100035793A1 (en) * | 2005-07-27 | 2010-02-11 | Cheh Peng Lim | Modulators |
| CA2634291A1 (en) * | 2005-12-22 | 2007-06-28 | Institut De Cardiologie De Montreal | Transcription factor decoy oligodeoxynucleotides having multiple cis elements |
| JPWO2007072909A1 (ja) | 2005-12-22 | 2009-06-04 | アンジェスＭｇ株式会社 | 新規オリゴヌクレオチド及びそれから成るＮＦ−κＢデコイ |
| JP4602298B2 (ja) * | 2006-08-31 | 2010-12-22 | ホソカワミクロン株式会社 | 医薬製剤 |
| US20100105762A1 (en) | 2007-02-16 | 2010-04-29 | Ryuichi Morishita | Therapeutic agent for periodontal disease and alveolar bone loss due to surgery |
| US20080249044A1 (en) * | 2007-04-03 | 2008-10-09 | Masaya Tanaka | Nucleic acid external skin formulation |
| DK2158316T3 (en) | 2007-05-11 | 2015-07-20 | Adynxx Inc | Gene expression and pain |
| WO2009119836A1 (ja) * | 2008-03-28 | 2009-10-01 | アンジェスＭｇ株式会社 | 転写因子デコイを有効成分とする外用剤組成物 |
| RU2668136C2 (ru) | 2012-05-10 | 2018-09-26 | Эйдинкс, Инк. | Композиции для доставки активных ингредиентов |
| JP6705807B2 (ja) | 2014-08-15 | 2020-06-03 | エーダイニクス インコーポレイテッド | 疼痛を治療するためのオリゴヌクレオチドデコイ |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2361756A (en) * | 1942-03-31 | 1944-10-31 | George W Fiero | Ointments and the like |
| JPS56135416A (en) * | 1980-03-27 | 1981-10-22 | Mitsubishi Chem Ind Ltd | Pharmaceutical preparation for skin |
| US4301145A (en) * | 1980-07-28 | 1981-11-17 | Cestari Joseph E | Antiseptic skin cream |
| US6410516B1 (en) * | 1986-01-09 | 2002-06-25 | President & Fellows Of Harvard College | Nuclear factors associated with transcriptional regulation |
| JPH05331066A (ja) * | 1992-05-25 | 1993-12-14 | Toko Yakuhin Kogyo Kk | 尋常性ざ瘡治療用組成物 |
| DE69435100D1 (de) * | 1993-10-29 | 2008-06-26 | Brigham & Womens Hospital | Therapeutische verwendung von cis-element-fallen in vivo |
| US6399376B1 (en) * | 1993-11-05 | 2002-06-04 | Isis Pharmaceuticals, Inc. | Modulation of vascular cell adhesive molecule expression through oligonucleotide interactions |
| US5869088A (en) * | 1994-10-24 | 1999-02-09 | Nikken Chemicals Co., Ltd | Transdermal administration preparation of a 9-aminocyclopenta (b) quinoline |
| ATE357922T1 (de) * | 1995-05-12 | 2007-04-15 | Anges Mg Inc | Heilung und vorbeugung von durch nf-kappab verursachten erkrankungen |
| CA2236825A1 (en) * | 1995-11-21 | 1997-05-29 | Icn Pharmaceuticals, Inc. | Inhibition of tumor growth by antisense oligonucleotides for il-8 and il-8 receptor |
| AU731909B2 (en) * | 1997-07-01 | 2001-04-05 | Isis Pharmaceuticals, Inc. | Compositions and methods for the delivery of oligonucleotides via the alimentary canal |
| JP2001055331A (ja) | 1999-06-11 | 2001-02-27 | Toyama Chem Co Ltd | アトピー性皮膚炎治療剤 |
| CN100542614C (zh) * | 2000-02-02 | 2009-09-23 | 安增子摩祺株式会社 | 用于基因转移的病毒包膜载体 |
| DE10049549A1 (de) | 2000-10-06 | 2002-05-02 | Markus Hecker | Modulation der Transkription pro-inflammatorischer Genprodukte |
| PT1362600E (pt) | 2001-02-20 | 2008-07-09 | Anges Mg Inc | Utilização tópica de iscos de nf-kb para o tratamento da dermatite atópica |
| JPWO2003063911A1 (ja) * | 2002-02-01 | 2006-01-19 | アンジェスＭｇ株式会社 | デコイを含む薬学的組成物およびその使用方法 |
| JP4971609B2 (ja) | 2004-08-27 | 2012-07-11 | アンジェスＭｇ株式会社 | 核酸皮膚外用製剤 |
| JP2006111591A (ja) | 2004-10-15 | 2006-04-27 | Anges Mg Inc | 核酸医薬を標的特異的に細胞内送達するための製剤 |
-
2002
- 2002-02-06 PT PT02711351T patent/PT1362600E/pt unknown
- 2002-02-06 EP EP06004446.8A patent/EP1690544B1/en not_active Expired - Lifetime
- 2002-02-06 JP JP2002565628A patent/JP3778357B2/ja not_active Expired - Lifetime
- 2002-02-06 DK DK02711351T patent/DK1362600T3/da active
- 2002-02-06 ES ES02711351T patent/ES2307733T3/es not_active Expired - Lifetime
- 2002-02-06 AT AT02711351T patent/ATE390938T1/de active
- 2002-02-06 EP EP02711351A patent/EP1362600B1/en not_active Expired - Lifetime
- 2002-02-06 DE DE60225899T patent/DE60225899T2/de not_active Expired - Lifetime
- 2002-02-06 WO PCT/JP2002/000990 patent/WO2002066070A1/ja not_active Ceased
- 2002-02-06 TW TW091102095A patent/TWI308492B/zh not_active IP Right Cessation
- 2002-02-06 US US10/468,717 patent/US9012417B2/en not_active Expired - Fee Related
-
2008
- 2008-06-30 CY CY20081100682T patent/CY1108165T1/el unknown
- 2008-12-02 US US12/314,009 patent/US20090105183A1/en not_active Abandoned
-
2009
- 2009-02-06 JP JP2009026797A patent/JP4987022B2/ja not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| EP1362600A1 (en) | 2003-11-19 |
| DE60225899T2 (de) | 2009-04-09 |
| EP1690544A3 (en) | 2012-03-07 |
| US9012417B2 (en) | 2015-04-21 |
| CY1108165T1 (el) | 2014-02-12 |
| EP1690544B1 (en) | 2017-09-13 |
| EP1362600A4 (en) | 2005-09-21 |
| ATE390938T1 (de) | 2008-04-15 |
| EP1362600B1 (en) | 2008-04-02 |
| PT1362600E (pt) | 2008-07-09 |
| JP2009102428A (ja) | 2009-05-14 |
| JPWO2002066070A1 (ja) | 2004-06-17 |
| JP3778357B2 (ja) | 2006-05-24 |
| ES2307733T3 (es) | 2008-12-01 |
| US20090105183A1 (en) | 2009-04-23 |
| WO2002066070A1 (fr) | 2002-08-29 |
| EP1690544A2 (en) | 2006-08-16 |
| US20040162251A1 (en) | 2004-08-19 |
| DE60225899D1 (de) | 2008-05-15 |
| JP4987022B2 (ja) | 2012-07-25 |
| DK1362600T3 (da) | 2008-07-28 |
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