TW593307B - Sulfonamide-substituted benzopyran derivatives, processes for their preparation, their use as a medicament, and pharmaceutical preparations comprising them - Google Patents

Sulfonamide-substituted benzopyran derivatives, processes for their preparation, their use as a medicament, and pharmaceutical preparations comprising them Download PDF

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Publication number
TW593307B
TW593307B TW087118010A TW87118010A TW593307B TW 593307 B TW593307 B TW 593307B TW 087118010 A TW087118010 A TW 087118010A TW 87118010 A TW87118010 A TW 87118010A TW 593307 B TW593307 B TW 593307B
Authority
TW
Taiwan
Prior art keywords
compound
formula
alkyl
patent application
alkoxy
Prior art date
Application number
TW087118010A
Other languages
English (en)
Chinese (zh)
Inventor
Joachim Brendel
Uwe Gerlach
Hans Jochen Lang
Klaus Weidmann
Original Assignee
Aventis Pharma Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Gmbh filed Critical Aventis Pharma Gmbh
Application granted granted Critical
Publication of TW593307B publication Critical patent/TW593307B/zh

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C07D311/70—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with two hydrocarbon radicals attached in position 2 and elements other than carbon and hydrogen in position 6
    • C07D311/72—3,4-Dihydro derivatives having in position 2 at least one methyl radical and in position 6 one oxygen atom, e.g. tocopherols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12—Antidiarrhoeals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
TW087118010A 1997-11-03 1998-10-30 Sulfonamide-substituted benzopyran derivatives, processes for their preparation, their use as a medicament, and pharmaceutical preparations comprising them TW593307B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19748469A DE19748469A1 (de) 1997-11-03 1997-11-03 Sulfonamid-substituierte Benzopyranderivate, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament sowie sie enthaltende pharmazeutische Zubereitungen

Publications (1)

Publication Number Publication Date
TW593307B true TW593307B (en) 2004-06-21

Family

ID=7847428

Family Applications (1)

Application Number Title Priority Date Filing Date
TW087118010A TW593307B (en) 1997-11-03 1998-10-30 Sulfonamide-substituted benzopyran derivatives, processes for their preparation, their use as a medicament, and pharmaceutical preparations comprising them

Country Status (29)

Country Link
US (1) US6008245A (de)
EP (1) EP0913396B1 (de)
JP (1) JP4430749B2 (de)
KR (1) KR19990044961A (de)
CN (1) CN1218050A (de)
AR (1) AR015997A1 (de)
AT (1) ATE250051T1 (de)
AU (1) AU740814B2 (de)
BR (1) BR9805088A (de)
CA (1) CA2252733A1 (de)
CZ (1) CZ293913B6 (de)
DE (2) DE19748469A1 (de)
DK (1) DK0913396T3 (de)
ES (1) ES2203867T3 (de)
HR (1) HRP980576B1 (de)
HU (1) HUP9802518A3 (de)
ID (1) ID21209A (de)
IL (1) IL126855A (de)
MY (1) MY118262A (de)
NO (1) NO985023L (de)
NZ (1) NZ332575A (de)
PL (1) PL329437A1 (de)
PT (1) PT913396E (de)
RU (1) RU2225403C2 (de)
SI (1) SI0913396T1 (de)
SK (1) SK284859B6 (de)
TR (1) TR199802200A3 (de)
TW (1) TW593307B (de)
ZA (1) ZA989982B (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5408940A (en) * 1992-06-25 1995-04-25 Winchell; Paul W. Adjustable height work surface wtih rack and pinion arrangements
DE19858253A1 (de) * 1998-12-17 2000-06-21 Aventis Pharma Gmbh Verwendung von Inhibitoren des KQt1-Kanals zur Herstellung eines Medikaments zur Behandlung von Krankheiten, die durch Helminthen und Ektoparasiten hervorgerufen werden
KR100512486B1 (ko) * 2003-05-28 2005-09-06 동부한농화학 주식회사 싸이옥소벤즈옥사졸 유도체로 치환된 벤조피란 유도체또는 약학적으로 허용되는 염, 이의 제조방법 및 이를포함하는 약학적 조성물
KR100545780B1 (ko) * 2003-05-28 2006-01-24 동부한농화학 주식회사 벤즈이미다졸 유도체로 치환된 벤조피란 유도체 또는약학적으로 허용되는 그의 염, 이의 제조 방법 및 이를포함하는 약학적 조성물
AU2006234295B2 (en) * 2005-04-12 2011-10-13 Solvay Pharmaceuticals Gmbh Aminoalkyl-amidomethyl-substituted 2-(4-sulphonylamino)-3-hydroxy-3,4-dihydro-2H-chromen-6-yl derivatives and their use as potassium channel blockers
EP2595623B1 (de) 2010-07-19 2018-02-28 The U.S.A. as represented by the Secretary, Department of Health and Human Services Verwendung von delta-tocopherol zur behandlung von lysosomale speicherkrankheiten
CN107954848A (zh) 2012-11-16 2018-04-24 美国健康及人类服务部 作为溶酶体贮积症的修复剂的生育酚和生育醌衍生物
WO2015047113A1 (en) * 2013-09-30 2015-04-02 Polfarmex S.A. Novel substituted n, n-dimethylaminoalkyl ethers of isoflavanone oximes as η1-receptor antagonists

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3737195A1 (de) * 1987-11-03 1989-05-18 Bayer Ag Chromanderivate, verfahren zu ihrer herstellung und ihre verwendung in arzneimitteln
GB8808069D0 (en) * 1988-04-07 1988-05-11 Fujisawa Pharmaceutical Co Benzopyran derivatives & processes for preparation thereof
US5104890A (en) * 1989-03-28 1992-04-14 Fujisawa Pharmaceutical Company, Ltd. Benzopyran derivatives and processes for preparation thereof
HRP970255B1 (en) * 1996-05-15 2003-10-31 Hoechst Ag Sulfonamido substituted chromane derivatives, method for their preparation, their use as medicaments or diagnostic agents as well as medicaments containing them
DE19706675A1 (de) * 1997-02-20 1998-08-27 Hoechst Ag Sulfonamid-substituierte Chromane, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament
DE19742509A1 (de) * 1997-09-26 1999-04-01 Hoechst Marion Roussel De Gmbh Sulfonamid-substituierte Chromane, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltende pharmazeutische Zubereitungen
DE19742508A1 (de) * 1997-09-26 1999-04-01 Hoechst Marion Roussel De Gmbh Sulfonamid-substituierte Chromane, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltende pharmazeutische Zubereitungen

Also Published As

Publication number Publication date
HUP9802518A3 (en) 2001-10-29
DK0913396T3 (da) 2003-12-22
RU2225403C2 (ru) 2004-03-10
TR199802200A2 (xx) 1999-05-21
IL126855A0 (en) 1999-09-22
SK284859B6 (sk) 2006-01-05
NO985023L (no) 1999-05-04
PT913396E (pt) 2004-02-27
SK149498A3 (en) 1999-05-07
EP0913396A2 (de) 1999-05-06
HU9802518D0 (en) 1998-12-28
DE19748469A1 (de) 1999-05-06
HRP980576B1 (en) 2002-10-31
JPH11222485A (ja) 1999-08-17
SI0913396T1 (en) 2004-02-29
EP0913396A3 (de) 2001-03-21
CA2252733A1 (en) 1999-05-03
PL329437A1 (en) 1999-05-10
NZ332575A (en) 2000-03-27
AU9043798A (en) 1999-05-20
ATE250051T1 (de) 2003-10-15
CZ293913B6 (cs) 2004-08-18
MY118262A (en) 2004-09-30
BR9805088A (pt) 2000-03-21
CN1218050A (zh) 1999-06-02
AR015997A1 (es) 2001-05-30
HRP980576A2 (en) 1999-06-30
KR19990044961A (ko) 1999-06-25
TR199802200A3 (tr) 1999-05-21
ZA989982B (en) 1999-06-24
DE59809628D1 (de) 2003-10-23
JP4430749B2 (ja) 2010-03-10
AU740814B2 (en) 2001-11-15
NO985023D0 (no) 1998-10-28
US6008245A (en) 1999-12-28
CZ350898A3 (cs) 1999-05-12
IL126855A (en) 2003-03-12
EP0913396B1 (de) 2003-09-17
ES2203867T3 (es) 2004-04-16
HUP9802518A2 (hu) 2000-06-28
ID21209A (id) 1999-05-06

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