TW201313743A - 抗親和性複合體之抗體 - Google Patents
抗親和性複合體之抗體 Download PDFInfo
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- TW201313743A TW201313743A TW101124860A TW101124860A TW201313743A TW 201313743 A TW201313743 A TW 201313743A TW 101124860 A TW101124860 A TW 101124860A TW 101124860 A TW101124860 A TW 101124860A TW 201313743 A TW201313743 A TW 201313743A
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- antibody
- affinity complex
- vitamin
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- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/26—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against hormones ; against hormone releasing or inhibiting factors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/44—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material not provided for elsewhere, e.g. haptens, metals, DNA, RNA, amino acids
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- G—PHYSICS
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- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
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- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/531—Production of immunochemical test materials
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
- G01N33/743—Steroid hormones
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
- G01N33/78—Thyroid gland hormones, e.g. T3, T4, TBH, TBG or their receptors
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/82—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving vitamins or their receptors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/32—Immunoglobulins specific features characterized by aspects of specificity or valency specific for a neo-epitope on a complex, e.g. antibody-antigen or ligand-receptor
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
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- Physics & Mathematics (AREA)
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- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
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| US10983136B2 (en) | 2013-01-28 | 2021-04-20 | Diasorin S.P.A. | Use of 1,25-dihydroxyvitamin D values in ratio with PTH as a prognostic biomarker |
| PT2759550T (pt) | 2013-01-28 | 2018-11-16 | Diasorin S P A | Método e kit para detetar 1,25-di-hidroxivitamina d e anticorpos relacionados |
| US11261257B2 (en) | 2013-01-28 | 2022-03-01 | Diasorin S.P.A. | Methods for detecting 1,25-dihydroxyvitamin D and related antibodies |
| JP6281497B2 (ja) | 2013-02-06 | 2018-02-21 | 富士レビオ株式会社 | ビタミンｄの測定方法および測定用キット |
| TW201536801A (zh) * | 2014-02-25 | 2015-10-01 | Fujirebio Kk | 改質單體ＩｇＭ |
| CA3047691C (en) | 2015-12-21 | 2022-12-06 | Turun Yliopisto | Antibodies against immunocomplexes comprising cyanobacterial cyclic peptide hepatotoxins |
| KR20180104080A (ko) * | 2016-01-22 | 2018-09-19 | 아피메딕스, 인코포레이티드 | 비타민 d 대사산물 검출용 장치 |
| CN106244562B (zh) * | 2016-05-20 | 2019-07-23 | 杭州奥泰生物技术股份有限公司 | 杂交瘤细胞株及其分泌的抗25羟基维生素d3单克隆抗体和应用 |
| US11435367B2 (en) * | 2016-07-29 | 2022-09-06 | Diazyme Laboratories, Inc. | Methods and kits for assaying a vitamin D moiety |
| EP3624811A4 (en) * | 2017-05-19 | 2021-03-10 | The Regents of The University of California | ANTIBODY-BASED CHEMICAL INDUCED DIMERIZER (ABCID) AS A MOLECULAR SWITCH FOR REGULATING CELL THERAPIES |
| JP7325336B2 (ja) | 2017-12-25 | 2023-08-14 | 富士レビオ株式会社 | マクロライド系免疫抑制剤についての血液検査方法 |
| JP7434824B2 (ja) * | 2019-11-20 | 2024-02-21 | 東ソー株式会社 | 抗イムノコンプレックス抗体を用いた測定方法 |
| CN114746754A (zh) * | 2019-11-20 | 2022-07-12 | 东曹株式会社 | 使用抗免疫复合物抗体的测定方法 |
| JP7683188B2 (ja) * | 2019-11-29 | 2025-05-27 | 東ソー株式会社 | 抗イムノコンプレックス抗体を用いた測定法 |
| CN113125696B (zh) * | 2019-12-31 | 2024-03-26 | 科美博阳诊断技术(上海)有限公司 | 一种雌二醇均相化学发光检测试剂盒及其应用 |
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| DE69233745D1 (de) | 1991-12-02 | 2008-10-23 | Cambridge Antibody Tech | Herstellung von Autoantikörpern auf Phagenoberflächen ausgehend von Antikörpersegmentbibliotheken |
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| US5639641A (en) | 1992-09-09 | 1997-06-17 | Immunogen Inc. | Resurfacing of rodent antibodies |
| ATE390933T1 (de) | 1995-04-27 | 2008-04-15 | Amgen Fremont Inc | Aus immunisierten xenomäusen stammende menschliche antikörper gegen il-8 |
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| JP2009082033A (ja) | 2007-09-28 | 2009-04-23 | Kaneka Corp | 完全ヒト型抗体生産法 |
| FI20085579A0 (fi) * | 2008-06-12 | 2008-06-12 | Valtion Teknillinen | Kannabiskäytön toteaminen |
| US20110097733A1 (en) * | 2009-10-27 | 2011-04-28 | Michel Anciaux | Process for the production of a hybridoma and antibody obtained therefrom, able to recognize more than one vitamin d metabolite |
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| WO2013042426A1 (ja) | 2013-03-28 |
| EP2759551A1 (en) | 2014-07-30 |
| BR112014006405A2 (pt) | 2017-04-04 |
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| JP6156144B2 (ja) | 2017-07-05 |
| EP2759551A4 (en) | 2015-03-04 |
| US9599608B2 (en) | 2017-03-21 |
| AU2012310880B2 (en) | 2015-12-03 |
| RU2014115676A (ru) | 2015-10-27 |
| EP2759551B1 (en) | 2019-05-22 |
| CN103827145A (zh) | 2014-05-28 |
| AU2012310880A1 (en) | 2014-04-10 |
| IL231404A0 (en) | 2014-04-30 |
| CA2849274C (en) | 2018-12-04 |
| IN2014CN02113A (cg-RX-API-DMAC7.html) | 2015-05-29 |
| US20150037813A1 (en) | 2015-02-05 |
| JPWO2013042426A1 (ja) | 2015-03-26 |
| KR20140044940A (ko) | 2014-04-15 |
| CA2849274A1 (en) | 2013-03-28 |
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